메뉴 건너뛰기




Volumn 59, Issue 7, 2010, Pages 1674-1685

The transcription factor Rfx3 regulates β-cell differentiation, function, and glucokinase expression

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOKINASE; GLUCOSE TRANSPORTER 2; INSULIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RFX3; UNCLASSIFIED DRUG;

EID: 77954285845     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db09-0986     Document Type: Article
Times cited : (57)

References (49)
  • 1
    • 0034652287 scopus 로고    scopus 로고
    • Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
    • Gradwohl G, Dierich A, LeMeur M, Guillemot F. Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A 2000;97:1607-1611
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1607-1611
    • Gradwohl, G.1    Dierich, A.2    LeMeur, M.3    Guillemot, F.4
  • 2
    • 33847217554 scopus 로고    scopus 로고
    • Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types
    • Johansson KA, Dursun U, Jordan N, Gu G, Beermann F, Gradwohl G, Grapin-Botton A. Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types. Dev Cell 2007;12:457-465
    • (2007) Dev Cell , vol.12 , pp. 457-465
    • Johansson, K.A.1    Dursun, U.2    Jordan, N.3    Gu, G.4    Beermann, F.5    Gradwohl, G.6    Grapin-Botton, A.7
  • 4
    • 0030886674 scopus 로고    scopus 로고
    • Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice
    • Naya FJ, Huang HP, Qiu Y, Mutoh H, DeMayo FJ, Leiter AB, Tsai MJ. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Genes Dev 1997;11:2323-2334 (Pubitemid 27408530)
    • (1997) Genes and Development , vol.11 , Issue.18 , pp. 2323-2334
    • Naya, F.J.1    Huang, H.-P.2    Qiu, Y.3    Mutoh, H.4    Demayo, F.J.5    Leiter, A.B.6    Tsai, M.-J.7
  • 6
    • 0031843386 scopus 로고    scopus 로고
    • Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells
    • Sussel L, Kalamaras J, Hartigan-O'Connor DJ, Meneses JJ, Pedersen RA, Rubenstein JL, German MS. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development 1998;125:2213-2221 (Pubitemid 28336383)
    • (1998) Development , vol.125 , Issue.12 , pp. 2213-2221
    • Sussel, L.1    Kalamaras, J.2    Hartigan-O'Connor, D.J.3    Meneses, J.J.4    Pedersen, R.A.5    Rubenstein, J.L.R.6    German, M.S.7
  • 10
    • 24144479748 scopus 로고    scopus 로고
    • Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas
    • Holland AM, Gonez LJ, Naselli G, Macdonald RJ, Harrison LC. Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas. Diabetes 2005;54:2586-2595
    • (2005) Diabetes , vol.54 , pp. 2586-2595
    • Holland, A.M.1    Gonez, L.J.2    Naselli, G.3    Macdonald, R.J.4    Harrison, L.C.5
  • 11
    • 51649112751 scopus 로고    scopus 로고
    • Identification and characterization of novel human tissue-specific RFX transcription factors
    • Aftab S, Semenec L, Chu JS, Chen N. Identification and characterization of novel human tissue-specific RFX transcription factors. BMC Evol Biol 2008;8:226
    • (2008) BMC Evol Biol , vol.8 , pp. 226
    • Aftab, S.1    Semenec, L.2    Chu, J.S.3    Chen, N.4
  • 12
    • 0029997190 scopus 로고    scopus 로고
    • RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom
    • Emery P, Durand B, Mach B, Reith W. RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom. Nucleic Acid Res 1996;24:803-807
    • (1996) Nucleic Acid Res , vol.24 , pp. 803-807
    • Emery, P.1    Durand, B.2    Mach, B.3    Reith, W.4
  • 13
    • 0028057841 scopus 로고
    • RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins
    • Reith W, Ucla C, Barras E, Gaud A, Durand B, Herrero-Sanchez C, Kobr M, Mach B. RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins. Mol Cell Biol 1994;14:1230-1244 (Pubitemid 24036574)
    • (1994) Molecular and Cellular Biology , vol.14 , Issue.2 , pp. 1230-1244
    • Reith, W.1    Ucla, C.2    Barras, E.3    Gaud, A.4    Durand, B.5    Herrero-Sanchez, C.6    Kobr, M.7    Mach, B.8
  • 14
    • 0035064073 scopus 로고    scopus 로고
    • The bare lymphocyte syndrome and the regulation of MHC expression
    • DOI 10.1146/annurev.immunol.19.1.331
    • Reith W, Mach B. The bare lymphocyte syndrome and the regulation of MHC expression. Annu Rev Immunol 2001;19:331-373 (Pubitemid 32368039)
    • (2001) Annual Review of Immunology , vol.19 , pp. 331-373
    • Reith, W.1    Mach, B.2
  • 15
    • 0142074402 scopus 로고    scopus 로고
    • Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4
    • Blackshear PJ, Graves JP, Stumpo DJ, Cobos I, Rubenstein JL, Zeldin DC. Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4. Development 2003;130:4539-4552
    • (2003) Development , vol.130 , pp. 4539-4552
    • Blackshear, P.J.1    Graves, J.P.2    Stumpo, D.J.3    Cobos, I.4    Rubenstein, J.L.5    Zeldin, D.C.6
  • 21
    • 0036340074 scopus 로고    scopus 로고
    • Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
    • Gu G, Dubauskaite J, Melton DA. Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 2002;129:2447-2457
    • (2002) Development , vol.129 , pp. 2447-2457
    • Gu, G.1    Dubauskaite, J.2    Melton, D.A.3
  • 23
    • 34548188298 scopus 로고    scopus 로고
    • Activation of RalA is required for insulin-stimulated Glut4 trafficking to the plasma membrane via the exocyst and the motor protein Myo1c
    • Chen XW, Leto D, Chiang SH, Wang Q, Saltiel AR. Activation of RalA is required for insulin-stimulated Glut4 trafficking to the plasma membrane via the exocyst and the motor protein Myo1c. Dev Cell 2007;13:391-404
    • (2007) Dev Cell , vol.13 , pp. 391-404
    • Chen, X.W.1    Leto, D.2    Chiang, S.H.3    Wang, Q.4    Saltiel, A.R.5
  • 24
    • 0043210428 scopus 로고    scopus 로고
    • Conditional suppression of cellular genes: Lentivirus vector-mediated drug-inducible RNA interference
    • DOI 10.1128/JVI.77.16.8957-8951.2003
    • Wiznerowicz M, Trono D. Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. J Virol 2003;77:8957-8961 (Pubitemid 36936105)
    • (2003) Journal of Virology , vol.77 , Issue.16 , pp. 8957-8961
    • Wiznerowicz, M.1    Trono, D.2
  • 25
    • 0037315584 scopus 로고    scopus 로고
    • 2+ oscillations and insulin secretion in MIN6 cells
    • DOI 10.2337/diabetes.52.2.417
    • Calabrese A, Zhang M, Serre-Beinier V, Caton D, Mas C, Satin LS, Meda P. Connexin 36 controls synchronization of Ca2+ oscillations and insulin secretion in MIN6 cells. Diabetes 2003;52:417-424 (Pubitemid 36173198)
    • (2003) Diabetes , vol.52 , Issue.2 , pp. 417-424
    • Calabrese, A.1    Zhang, M.2    Serre-Beinier, V.3    Caton, D.4    Mas, C.5    Satin, L.S.6    Meda, P.7
  • 26
    • 0037320461 scopus 로고    scopus 로고
    • Chromatin remodeling and extragenic transcription at the MHC class II locus control region
    • DOI 10.1038/ni883
    • Masternak K, Peyraud N, Krawczyk M, Barras E, Reith W. Chromatin remodeling and extragenic transcription at the MHC class II locus control region. Nat Immunol 2003;4:132-137 (Pubitemid 36193014)
    • (2003) Nature Immunology , vol.4 , Issue.2 , pp. 132-137
    • Masternak, K.1    Peyraud, N.2    Krawczyk, M.3    Barras, E.4    Reith, W.5
  • 28
    • 0034121735 scopus 로고    scopus 로고
    • Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages
    • Herrera PL. Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development 2000;127:2317-2322
    • (2000) Development , vol.127 , pp. 2317-2322
    • Herrera, P.L.1
  • 29
    • 0032428685 scopus 로고    scopus 로고
    • Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein
    • Nonaka S, Tanaka Y, Okada Y, Takeda S, Harada A, Kanai Y, Kido M, Hirokawa N. Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell 1998;95:829-837
    • (1998) Cell , vol.95 , pp. 829-837
    • Nonaka, S.1    Tanaka, Y.2    Okada, Y.3    Takeda, S.4    Harada, A.5    Kanai, Y.6    Kido, M.7    Hirokawa, N.8
  • 30
    • 0029982706 scopus 로고    scopus 로고
    • A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity
    • Emery P, Strubin M, Hofmann K, Bucher P, Mach B, Reith W. A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity. Mol Cell Biol 1996;16:4486-4494
    • (1996) Mol Cell Biol , vol.16 , pp. 4486-4494
    • Emery, P.1    Strubin, M.2    Hofmann, K.3    Bucher, P.4    Mach, B.5    Reith, W.6
  • 31
    • 0028101926 scopus 로고
    • Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut
    • Jetton TL, Liang Y, Pettepher CC, Zimmerman EC, Cox FG, Horvath K, Matschinsky FM, Magnuson MA. Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut. J Biol Chem 1994;269:3641-3654
    • (1994) J Biol Chem , vol.269 , pp. 3641-3654
    • Jetton, T.L.1    Liang, Y.2    Pettepher, C.C.3    Zimmerman, E.C.4    Cox, F.G.5    Horvath, K.6    Matschinsky, F.M.7    Magnuson, M.A.8
  • 33
    • 0028057602 scopus 로고
    • Positive and negative regulatory elements are involved in transcriptional control of the rat glucokinase gene in the insulin producing cell line HIT M2.2.2
    • Leibiger IB, Walther R, Pett U, Leibiger B. Positive and negative regulatory elements are involved in transcriptional control of the rat glucokinase gene in the insulin producing cell line HIT M2.2.2. FEBS Lett 1994;337:161-166
    • (1994) FEBS Lett , vol.337 , pp. 161-166
    • Leibiger, I.B.1    Walther, R.2    Pett, U.3    Leibiger, B.4
  • 34
    • 0026687778 scopus 로고
    • Multiple elements in the upstream glucokinase promoter contribute to transcription in insulinoma cells
    • Shelton KD, Franklin AJ, Khoor A, Beechem J, Magnuson MA. Multiple elements in the upstream glucokinase promoter contribute to transcription in insulinoma cells. Mol Cell Biol 1992;12:4578-4589
    • (1992) Mol Cell Biol , vol.12 , pp. 4578-4589
    • Shelton, K.D.1    Franklin, A.J.2    Khoor, A.3    Beechem, J.4    Magnuson, M.A.5
  • 35
    • 0029938124 scopus 로고    scopus 로고
    • Characterization of the Pal motifs in the upstream glucokinase promoter: Binding of a cell type-specific protein complex correlates with transcriptional activation
    • Moates JM, Shelton KD, Magnuson MA. Characterization of the Pal motifs in the upstream glucokinase promoter: binding of a cell type-specific protein complex correlates with transcriptional activation. Mol Endocrinol 1996;10:723-731
    • (1996) Mol Endocrinol , vol.10 , pp. 723-731
    • Moates, J.M.1    Shelton, K.D.2    Magnuson, M.A.3
  • 36
    • 33746163080 scopus 로고    scopus 로고
    • Transcriptional regulation of glucose sensors in pancreatic beta cells and liver
    • Im SS, Kim SY, Kim HI, Ahn YH. Transcriptional regulation of glucose sensors in pancreatic beta cells and liver. Curr Diabetes Rev 2006;2:11-18
    • (2006) Curr Diabetes Rev , vol.2 , pp. 11-18
    • Im, S.S.1    Kim, S.Y.2    Kim, H.I.3    Ahn, Y.H.4
  • 37
    • 34249051680 scopus 로고    scopus 로고
    • Immunohistochemical evidence for the presence of glucokinase in the gonadotropes and thyrotropes of the anterior pituitary gland of rat and monkey
    • Sorenson RL, Stout LE, Brelje TC, Jetton TL, Matschinsky FM. Immunohistochemical evidence for the presence of glucokinase in the gonadotropes and thyrotropes of the anterior pituitary gland of rat and monkey. J Histochem Cytochem 2007;55:555-566
    • (2007) J Histochem Cytochem , vol.55 , pp. 555-566
    • Sorenson, R.L.1    Stout, L.E.2    Brelje, T.C.3    Jetton, T.L.4    Matschinsky, F.M.5
  • 39
    • 5644297238 scopus 로고    scopus 로고
    • The Pal elements in the upstream glucokinase promoter exhibit dyad symmetry and display cell-specific enhancer activity when multimerised
    • Moates JM, Magnuson MA. The Pal elements in the upstream glucokinase promoter exhibit dyad symmetry and display cell-specific enhancer activity when multimerised. Diabetologia 2004;47:1632-1640
    • (2004) Diabetologia , vol.47 , pp. 1632-1640
    • Moates, J.M.1    Magnuson, M.A.2
  • 40
    • 0037315195 scopus 로고    scopus 로고
    • BETA2 activates transcription from the upstream glucokinase gene promoter in islet beta-cells and gut endocrine cells
    • DOI 10.2337/diabetes.52.2.403
    • Moates JM, Nanda S, Cissell MA, Tsai MJ, Stein R. BETA2 activates transcription from the upstream glucokinase gene promoter in islet beta-cells and gut endocrine cells. Diabetes 2003;52:403-408 (Pubitemid 36173196)
    • (2003) Diabetes , vol.52 , Issue.2 , pp. 403-408
    • Moates, J.M.1    Nanda, S.2    Cissell, M.A.3    Tsai, M.-J.4    Stein, R.5
  • 41
    • 0029909387 scopus 로고    scopus 로고
    • The human glucokinase gene beta-cell-type promoter: An essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells
    • Watada H, Kajimoto Y, Umayahara Y, Matsuoka T, Kaneto H, Fujitani Y, Kamada T, Kawamori R, Yamasaki Y. The human glucokinase gene beta-cell-type promoter: an essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells. Diabetes 1996;45:1478-1488 (Pubitemid 26357538)
    • (1996) Diabetes , vol.45 , Issue.11 , pp. 1478-1488
    • Watada, H.1    Kajimoto, Y.2    Umayahara, Y.3    Matsuoka, T.-A.4    Kaneto, H.5    Fujitani, Y.6    Kamada, T.7    Kawamori, R.8    Yamasaki, Y.9
  • 42
    • 0029417331 scopus 로고
    • Pancreatic beta-cell-specific targeted disruption of glucokinase gene: Diabetes mellitus due to defective insulin secretion to glucose
    • Terauchi Y, Sakura H, Yasuda K, Iwamoto K, Takahashi N, Ito K, Kasai H, Suzuki H, Ueda O, Kamada N, et al. Pancreatic beta-cell-specific targeted disruption of glucokinase gene: diabetes mellitus due to defective insulin secretion to glucose. J Biol Chem 1995;270:30253-30256
    • (1995) J Biol Chem , vol.270 , pp. 30253-30256
    • Terauchi, Y.1    Sakura, H.2    Yasuda, K.3    Iwamoto, K.4    Takahashi, N.5    Ito, K.6    Kasai, H.7    Suzuki, H.8    Ueda, O.9    Kamada, N.10
  • 44
    • 0242384237 scopus 로고    scopus 로고
    • Glucokinase (GCK) mutations in hyper- and hypoglycemia: Maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemia of infancy
    • Gloyn AL. Glucokinase (GCK) mutations in hyper- and hypoglycemia: maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemia of infancy. Hum Mutat 2003;22:353-362
    • (2003) Hum Mutat , vol.22 , pp. 353-362
    • Gloyn, A.L.1
  • 46
    • 53149104775 scopus 로고    scopus 로고
    • Glucose regulation of insulin gene expression in pancreatic beta-cells
    • Andrali SS, Sampley ML, Vanderford NL, Ozcan S. Glucose regulation of insulin gene expression in pancreatic beta-cells. Biochem J 2008;415:1-10
    • (2008) Biochem J , vol.415 , pp. 1-10
    • Andrali, S.S.1    Sampley, M.L.2    Vanderford, N.L.3    Ozcan, S.4
  • 47
    • 33845661591 scopus 로고    scopus 로고
    • Primary cilia deletion in pancreatic epithelial cells results in cyst formation and pancreatitis
    • Cano DA, Sekine S, Hebrok M. Primary cilia deletion in pancreatic epithelial cells results in cyst formation and pancreatitis. Gastroenterology 2006;131:1856-1869
    • (2006) Gastroenterology , vol.131 , pp. 1856-1869
    • Cano, D.A.1    Sekine, S.2    Hebrok, M.3
  • 48


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.