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Volumn 40, Issue 5, 1997, Pages 487-495

The pancreatic beta-cell as a fuel sensor: An electrophysiologist's viewpoint

Author keywords

ATP; exocytosis; insulin; ion channels; pancreas

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; INSULIN; POTASSIUM CHANNEL; SULFONYLUREA DERIVATIVE;

EID: 0030894850     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250050706     Document Type: Review
Times cited : (249)

References (56)
  • 1
    • 84944811856 scopus 로고
    • A further contribution regarding the influence of the different constituents of blood on the contraction of the heart
    • Ringer S (1883) A further contribution regarding the influence of the different constituents of blood on the contraction of the heart. J Physiol 4: 29-42
    • (1883) J Physiol , vol.4 , pp. 29-42
    • Ringer, S.1
  • 2
    • 0014432182 scopus 로고
    • Electrical activity in pancreatic islet cells
    • Dean PM, Matthews EK (1968) Electrical activity in pancreatic islet cells. Nature 219: 389-390
    • (1968) Nature , vol.219 , pp. 389-390
    • Dean, P.M.1    Matthews, E.K.2
  • 3
    • 0017670643 scopus 로고
    • Action potentials occur in cells of the normal anterior pituitary gland and are stimulated by the hypophysiotropic peptide thyrotropin releasing hormone
    • Taraskevich PS, Douglas WW (1977) Action potentials occur in cells of the normal anterior pituitary gland and are stimulated by the hypophysiotropic peptide thyrotropin releasing hormone. Proc Natl Acad Sci USA 74: 4064-4067
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 4064-4067
    • Taraskevich, P.S.1    Douglas, W.W.2
  • 5
    • 0021679735 scopus 로고
    • Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic B-cells
    • Henquin JC, Meissner HP (1984) Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic B-cells. Experientia 40: 1043-1052
    • (1984) Experientia , vol.40 , pp. 1043-1052
    • Henquin, J.C.1    Meissner, H.P.2
  • 6
  • 7
    • 0019441262 scopus 로고
    • Improved patch-clamp techniques for the recording from cells and cell-free membrane patches
    • Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ (1981) Improved patch-clamp techniques for the recording from cells and cell-free membrane patches. Pflügers Arch 291: 85-100
    • (1981) Pflügers Arch , vol.291 , pp. 85-100
    • Hamill, O.P.1    Marty, A.2    Neher, E.3    Sakmann, B.4    Sigworth, F.J.5
  • 8
    • 0021187646 scopus 로고
    • +-channels in pancreatic B-cells
    • +-channels in pancreatic B-cells. Nature 312: 271-273
    • (1984) Nature , vol.312 , pp. 271-273
    • Cook, D.L.1    Hales, C.N.2
  • 9
    • 0021741559 scopus 로고
    • Glucose induces closure of single potassium channels in isolated rat pancreatic β-cells
    • Ashcroft FM, Harrison DE, Ashcroft SJH (1984) Glucose induces closure of single potassium channels in isolated rat pancreatic β-cells. Nature 312: 446-448
    • (1984) Nature , vol.312 , pp. 446-448
    • Ashcroft, F.M.1    Harrison, D.E.2    Ashcroft, S.J.H.3
  • 10
    • 0022375444 scopus 로고
    • +-channels in pancreatic β-cells are regulated by intracellular ATP
    • +-channels in pancreatic β-cells are regulated by intracellular ATP. Pflügers Arch 405: 305-309
    • (1985) Pflügers Arch , vol.405 , pp. 305-309
    • Rorsman, P.1    Trube, G.2
  • 12
    • 0022977359 scopus 로고
    • +-channels that are inhibited by ATP in an insulin-secreting cell line
    • +-channels that are inhibited by ATP in an insulin-secreting cell line. FEBS Lett 208: 59-62
    • (1986) FEBS Lett , vol.208 , pp. 59-62
    • Dunne, M.J.1    Petersen, O.H.2
  • 13
    • 0022557304 scopus 로고
    • Calcium and potassium currents in mouse pancreatic β-cells under voltage-clamp conditions
    • Rorsman P, Trube G (1986) Calcium and potassium currents in mouse pancreatic β-cells under voltage-clamp conditions. J Physiol 374: 531-550
    • (1986) J Physiol , vol.374 , pp. 531-550
    • Rorsman, P.1    Trube, G.2
  • 14
    • 0023734073 scopus 로고
    • Single Ca channel currents in mouse pancreatic B-cells
    • Rorsman P, Ashcroft FM, Trube G (1988) Single Ca channel currents in mouse pancreatic B-cells. Pflügers Arch 412: 597-603
    • (1988) Pflügers Arch , vol.412 , pp. 597-603
    • Rorsman, P.1    Ashcroft, F.M.2    Trube, G.3
  • 17
    • 0021840516 scopus 로고
    • The sulfonylurea receptor may be an ATP-sensitive potassium channel
    • Sturgess NC, Ashford MLJ, Cook DL, Hales CN (1985) The sulfonylurea receptor may be an ATP-sensitive potassium channel. Lancet II: 474-475
    • (1985) Lancet , vol.2 , pp. 474-475
    • Sturgess, N.C.1    Ashford, M.L.J.2    Cook, D.L.3    Hales, C.N.4
  • 20
    • 0029024314 scopus 로고
    • Cloning of the β-cell high-affinity sulfonylurea receptor: A regulator of insulin secretion
    • Aguilar-Bryan L, Nichols CG, Herrera-Sosa H, Nguy K, Bryan J, Nelson DA (1995) Cloning of the β-cell high-affinity sulfonylurea receptor: a regulator of insulin secretion. Science 268: 423-426
    • (1995) Science , vol.268 , pp. 423-426
    • Aguilar-Bryan, L.1    Nichols, C.G.2    Herrera-Sosa, H.3    Nguy, K.4    Bryan, J.5    Nelson, D.A.6
  • 21
    • 0028972501 scopus 로고
    • KATP: An inward rectifier subunit plus the sulfonylurea receptor
    • KATP: an inward rectifier subunit plus the sulfonylurea receptor. Science 270: 1166-1170
    • (1995) Science , vol.270 , pp. 1166-1170
    • Inagaki, N.1    Gonoi, T.2    Clement IV, J.P.3
  • 22
    • 0029561629 scopus 로고    scopus 로고
    • Cloning and the functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic β-cells, brain, heart and skeletal muscle
    • Sakura H, Ämmälä C, Smith PA, Gribble FM, Ashcroft FM (1996) Cloning and the functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic β-cells, brain, heart and skeletal muscle. FEBS Lett 377: 338-344
    • (1996) FEBS Lett , vol.377 , pp. 338-344
    • Sakura, H.1    Ämmälä, C.2    Smith, P.A.3    Gribble, F.M.4    Ashcroft, F.M.5
  • 23
    • 0030016913 scopus 로고    scopus 로고
    • Adenosine diphosphate as an intracellular regulator of insulin secretion
    • Nichols CG, Shyng SL, Nestorowicz A et al. (1996) Adenosine diphosphate as an intracellular regulator of insulin secretion. Science 272: 1785-1787
    • (1996) Science , vol.272 , pp. 1785-1787
    • Nichols, C.G.1    Shyng, S.L.2    Nestorowicz, A.3
  • 24
    • 0026766318 scopus 로고
    • Cytoplasmic calcium transients due to single action potentials and voltage-clamp depolarizations in mouse pancreatic B-cells
    • Rorsman P, Ämmälä C, Berggren PO, Bokvist K, Larsson O (1992) Cytoplasmic calcium transients due to single action potentials and voltage-clamp depolarizations in mouse pancreatic B-cells. EMBO J 11: 2877-2884
    • (1992) EMBO J , vol.11 , pp. 2877-2884
    • Rorsman, P.1    Ämmälä, C.2    Berggren, P.O.3    Bokvist, K.4    Larsson, O.5
  • 25
    • 0029658788 scopus 로고    scopus 로고
    • ATP channels in pancreatic β-cells causes persistent hyperinsulinemic hypoglycemia of infancy
    • ATP channels in pancreatic β-cells causes persistent hyperinsulinemic hypoglycemia of infancy. Nature Med 2: 1344-1347
    • (1996) Nature Med , vol.2 , pp. 1344-1347
    • Kane, C.1    Shepherd, R.M.2    Squires, P.E.3
  • 26
    • 0029021696 scopus 로고
    • Mutations of the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy
    • Thomas PM, Cote GJ, Wohlik N et al. (1995) Mutations of the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy. Science 268: 426-429
    • (1995) Science , vol.268 , pp. 426-429
    • Thomas, P.M.1    Cote, G.J.2    Wohlik, N.3
  • 27
    • 0024332004 scopus 로고
    • 2+-channels by glucose metabolism in mouse pancreatic B-cells
    • 2+-channels by glucose metabolism in mouse pancreatic B-cells. Nature 342: 550-553
    • (1989) Nature , vol.342 , pp. 550-553
    • Smith, P.A.1    Rorsman, P.2    Ashcroft, F.M.3
  • 28
    • 0028140161 scopus 로고
    • Two sites of glucose control of insulin release with distinct dependence on the energy state in pancreatic B-cells
    • Detimary P, Gilon P, Nenquin M, Henquin JC (1994) Two sites of glucose control of insulin release with distinct dependence on the energy state in pancreatic B-cells. Biochem J 297: 455-461
    • (1994) Biochem J , vol.297 , pp. 455-461
    • Detimary, P.1    Gilon, P.2    Nenquin, M.3    Henquin, J.C.4
  • 29
    • 0013657423 scopus 로고
    • Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine chromaffin cells
    • Neher E, Marty A (1982) Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine chromaffin cells. Proc Natl Acad Sci USA 79: 6712-6716
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 6712-6716
    • Neher, E.1    Marty, A.2
  • 30
    • 0015610440 scopus 로고
    • Ultrastructural morphometry of the pancreatic beta-cell
    • Dean PM (1973) Ultrastructural morphometry of the pancreatic beta-cell. Diabetologia 9: 115-119
    • (1973) Diabetologia , vol.9 , pp. 115-119
    • Dean, P.M.1
  • 31
    • 0027763496 scopus 로고
    • Exocytosis elicited by action potentials and voltage-clamp calcium currents in individual mouse pancreatic B-cells
    • Ämmälä C, Eliasson L, Bokvist K, Larsson O, Ashcroft FM, Rorsman P (1993) Exocytosis elicited by action potentials and voltage-clamp calcium currents in individual mouse pancreatic B-cells. J Physiol 472: 665-688
    • (1993) J Physiol , vol.472 , pp. 665-688
    • Ämmälä, C.1    Eliasson, L.2    Bokvist, K.3    Larsson, O.4    Ashcroft, F.M.5    Rorsman, P.6
  • 32
    • 0028984692 scopus 로고
    • 2+-channels and insulin-containing granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells
    • 2+-channels and insulin-containing granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells. EMBO J 14: 50-57
    • (1995) EMBO J , vol.14 , pp. 50-57
    • Bokvist, K.1    Eliasson, L.2    Ämmälä, C.3    Renström, E.4    Rorsman, P.5
  • 33
    • 0030004317 scopus 로고    scopus 로고
    • Cooling inhibits exocytosis in single mouse B-cells by suppression of granule mobilization
    • Renström E, Eliasson L, Bokvist K, Rorsman P (1996) Cooling inhibits exocytosis in single mouse B-cells by suppression of granule mobilization. J Physiol 494: 41-52
    • (1996) J Physiol , vol.494 , pp. 41-52
    • Renström, E.1    Eliasson, L.2    Bokvist, K.3    Rorsman, P.4
  • 34
    • 0027235323 scopus 로고
    • 2+-independent potentiation of insulin release by cyclic AMP in pancreatic β-cells
    • 2+-independent potentiation of insulin release by cyclic AMP in pancreatic β-cells. Nature 363: 556-558
    • (1993) Nature , vol.363 , pp. 556-558
    • Ämmälä, C.1    Ashcroft, F.M.2    Rorsman, P.3
  • 35
    • 0028205382 scopus 로고
    • Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in insulin-secreting mouse pancreatic B-cells
    • Ämmälä C, Eliasson L, Bokvist K et al. (1994) Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in insulin-secreting mouse pancreatic B-cells. Proc Natl Acad Sci USA 91: 4343-4347
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4343-4347
    • Ämmälä, C.1    Eliasson, L.2    Bokvist, K.3
  • 36
    • 0030015561 scopus 로고    scopus 로고
    • Endocytosis of secretory granules in pancreatic β-cells evoked by transient elevation of cytosolic calcium
    • Eliasson L, Proks L, Ämmälä C et al. (1996) Endocytosis of secretory granules in pancreatic β-cells evoked by transient elevation of cytosolic calcium. J Physiol 493: 755-767
    • (1996) J Physiol , vol.493 , pp. 755-767
    • Eliasson, L.1    Proks, L.2    Ämmälä, C.3
  • 38
    • 0030245732 scopus 로고    scopus 로고
    • Neurotransmitter-induced inhibition of exocytosis in insulin-secreting β-cells by activation of calcineurin
    • Renström E, Ding WG, Bokvist K, Rorsman P (1996) Neurotransmitter-induced inhibition of exocytosis in insulin-secreting β-cells by activation of calcineurin. Neuron 17: 513-522
    • (1996) Neuron , vol.17 , pp. 513-522
    • Renström, E.1    Ding, W.G.2    Bokvist, K.3    Rorsman, P.4
  • 39
    • 13344269671 scopus 로고    scopus 로고
    • PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic β cells
    • Eliasson L, Renström E, Ämmälä C et al. (1996) PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic β cells. Science 271: 813-815
    • (1996) Science , vol.271 , pp. 813-815
    • Eliasson, L.1    Renström, E.2    Ämmälä, C.3
  • 42
    • 0028821526 scopus 로고
    • Intracellular localization and molecular heterogeneity of the sulphonylurea receptor in insulin-secreting cells
    • Ozanne SE, Guest PC, Hutton JC, Hales CN (1995) Intracellular localization and molecular heterogeneity of the sulphonylurea receptor in insulin-secreting cells. Diabetologia 38: 277-282
    • (1995) Diabetologia , vol.38 , pp. 277-282
    • Ozanne, S.E.1    Guest, P.C.2    Hutton, J.C.3    Hales, C.N.4
  • 43
    • 0026668998 scopus 로고
    • + conductance in pancreatic zymogen granules: Block by glyburide and activation by diazoxide
    • + conductance in pancreatic zymogen granules: block by glyburide and activation by diazoxide. J Membr Biol 129: 253-256
    • (1992) J Membr Biol , vol.129 , pp. 253-256
    • Thévenod, F.1    Chathadi, K.V.2    Jiang, B.3    Hopfer, U.4
  • 44
    • 0343602237 scopus 로고    scopus 로고
    • Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels
    • Ämmälä C, Moorhouse A, Gribble F et al. (1996) Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels. Nature 379: 545-548
    • (1996) Nature , vol.379 , pp. 545-548
    • Ämmälä, C.1    Moorhouse, A.2    Gribble, F.3
  • 45
    • 0029062006 scopus 로고
    • Stimulation of glucose uptake and increased plasma membrane content of glucose transporters in L6 skeletal muscle cells by the sulfonylureas gliclazide and glyburide
    • Tsiani E, Ramlal T, Leiter LA, Klip A, Fantus IG (1995) Stimulation of glucose uptake and increased plasma membrane content of glucose transporters in L6 skeletal muscle cells by the sulfonylureas gliclazide and glyburide. Endocrinology 136: 2505-2512
    • (1995) Endocrinology , vol.136 , pp. 2505-2512
    • Tsiani, E.1    Ramlal, T.2    Leiter, L.A.3    Klip, A.4    Fantus, I.G.5
  • 46
    • 0027449203 scopus 로고
    • The sulfonylurea drug, glimepiride, stimulates glucose transport, glucose transporter translocation, and dephosphorylation in insulin-resistant rat adipocytes in vitro
    • Müller G, Wied S (1993) The sulfonylurea drug, glimepiride, stimulates glucose transport, glucose transporter translocation, and dephosphorylation in insulin-resistant rat adipocytes in vitro. Diabetes 42: 1852-1867
    • (1993) Diabetes , vol.42 , pp. 1852-1867
    • Müller, G.1    Wied, S.2
  • 48
    • 0022555836 scopus 로고
    • Hormonal regulation of mammalian glucose transport
    • Simpson IA, Cushman SW (1986) Hormonal regulation of mammalian glucose transport. Ann Rev Biochem 55: 1055-1089
    • (1986) Ann Rev Biochem , vol.55 , pp. 1055-1089
    • Simpson, I.A.1    Cushman, S.W.2
  • 49
    • 1442295107 scopus 로고
    • Regulation of cellular membrane transport by the exocytotic insertion and endocytotic retrieval of transporters
    • Lienhard GE (1983) Regulation of cellular membrane transport by the exocytotic insertion and endocytotic retrieval of transporters. Trends Biochem Sci 8: 125-127
    • (1983) Trends Biochem Sci , vol.8 , pp. 125-127
    • Lienhard, G.E.1
  • 50
    • 11944258877 scopus 로고
    • 2+ but not for GTPγS induced insulin secretion
    • 2+ but not for GTPγS induced insulin secretion. EMBO J 14: 2723-2730
    • (1995) EMBO J , vol.14 , pp. 2723-2730
    • Regazzi, R.1    Wollheim, C.B.2    Lang, J.3
  • 51
    • 0028862292 scopus 로고
    • Docked granules, the exocytotic burst and the need for ATP hydrolysis in endocrine cells
    • Parsons TD, Coorssen JR, Horstmann H, Almers W (1995) Docked granules, the exocytotic burst and the need for ATP hydrolysis in endocrine cells. Neuron 15: 1085-1096
    • (1995) Neuron , vol.15 , pp. 1085-1096
    • Parsons, T.D.1    Coorssen, J.R.2    Horstmann, H.3    Almers, W.4
  • 52
    • 0027409301 scopus 로고
    • Multiple calcium dependent processes related to secretion in bovine chromaffin cells
    • Neher E, Zucker RS (1993) Multiple calcium dependent processes related to secretion in bovine chromaffin cells. Neuron 10: 21-30
    • (1993) Neuron , vol.10 , pp. 21-30
    • Neher, E.1    Zucker, R.S.2
  • 53
    • 0002084588 scopus 로고
    • An update on implications of phasic insulin secretion
    • Pickup J, Williams G (eds) Blackwell Scientific Publications, Oxford
    • Grodsky GM (1994) An update on implications of phasic insulin secretion. In: Pickup J, Williams G (eds) Textbook of diabetes. Blackwell Scientific Publications, Oxford, Vol. 1, pp. 421-430
    • (1994) Textbook of Diabetes , vol.1 , pp. 421-430
    • Grodsky, G.M.1
  • 54
    • 0006736211 scopus 로고
    • Increased activity of the glucose cycle in the liver: Early characteristic of type 2 diabetes
    • Efendic S, Wajngot A, Vranic M (1985) Increased activity of the glucose cycle in the liver: early characteristic of type 2 diabetes. Proc Natl Acad Sci USA 82: 2965-2969
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 2965-2969
    • Efendic, S.1    Wajngot, A.2    Vranic, M.3
  • 56
    • 0008475916 scopus 로고
    • Pancreatic abnormalities in non-insulin-dependent diabetes mellitus
    • Pickup J, Williams G (eds) Blackwell Scientific Publications, Oxford
    • Ramirez LC, Raskin P (1991) Pancreatic abnormalities in non-insulin-dependent diabetes mellitus. In: Pickup J, Williams G (eds) Textbook of diabetes. Blackwell Scientific Publications, Oxford, Vol. 1, pp. 198-204
    • (1991) Textbook of Diabetes , vol.1 , pp. 198-204
    • Ramirez, L.C.1    Raskin, P.2


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