XRCC1 phosphorylation by CK2 is required for its stability and efficient DNA repair

DNA Repair

Volumn 9, Issue 7, 2010, Pages 835-841

  Parsons, Jason L ^a   Dianova, Irina I ^a   Finch, David ^a   Tait, Phillip S ^a   Ström, Cecilia E ^b   Helleday, Thomas ^a,b   Dianov, Grigory L ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Base excision repair; Phosphorylation; Protein stability; XRCC1

Indexed keywords

CASEIN KINASE II; SMALL INTERFERING RNA; XRCC1 PROTEIN;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME ACTIVITY; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY;

CASEIN KINASE II; CELL LINE; CYTOPLASM; DNA LIGASES; DNA REPAIR; DNA-BINDING PROTEINS; HUMANS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STABILITY; RNA, SMALL INTERFERING; UBIQUITINATION;

EID: 77953364327     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2010.04.008     Document Type: Article

References (26)

1. Ahmed K., Gerber D.A., and Cochet C. Joining the cell survival squad: an emerging role for protein kinase CK2. Trends Cell Biol. 12 (2002) 226-230
2. Ahn B., Harrigan J.A., Indig F.E., Wilson III D.M., and Bohr V.A. Regulation of WRN helicase activity in human base excision repair. J. Biol. Chem. 279 (2004) 53465-53474
3. Barz T., Ackermann K., Dubois G., Eils R., and Pyerin W. Genome-wide expression screens indicate a global role for protein kinase CK2 in chromatin remodeling. J. Cell Sci. 116 (2003) 1563-1577
4. Caldecott K.W. XRCC1 and DNA strand break repair. DNA Repair (Amst.) 2 (2003) 955-969
5. Caldecott K.W., Aoufouchi S., Johnson P., and Shall S. XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly(ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro. Nucl. Acids Res. 24 (1996) 4387-4394
6. Caldecott K.W., McKeown C.K., Tucker J.D., Ljungquist S., and Thompson L.H. An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III. Mol. Cell Biol. 14 (1994) 68-76
7. Cappelli E., Taylor R., Cevasco M., Abbondandolo A., Caldecott K., and Frosina G. Involvement of XRCC1 and DNA ligase III gene products in DNA base excision repair. J. Biol. Chem. 272 (1997) 23970-23975
8. Chou W.C., Wang H.C., Wong F.H., Ding S.L., Wu P.E., Shieh S.Y., and Shen C.Y. Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair. EMBO J. 27 (2008) 3140-3150
9. Dianov G.L., and Parsons J.L. Co-ordination of DNA single strand break repair. DNA Repair (Amst.) 6 (2007) 454-460
10. Dianov G.L., Sleeth K.M., Dianova I.I., and Allinson S.L. Repair of abasic sites in DNA. Mutat. Res. 531 (2003) 157-163
11. Fan J., Otterlei M., Wong H.K., Tomkinson A.E., and Wilson III D.M. XRCC1 co-localizes and physically interacts with PCNA. Nucl. Acids Res. 32 (2004) 2193-2201
12. Hunter T. The age of crosstalk: phosphorylation, ubiquitination, and beyond. Mol. Cell 28 (2007) 730-738
13. Johansson F., Lagerqvist A., Erixon K., and Jenssen D. A method to monitor replication fork progression in mammalian cells: nucleotide excision repair enhances and homologous recombination delays elongation along damaged DNA. Nucl. Acids Res. 32 (2004) e157
14. Kubota Y., and Horiuchi S. Independent roles of XRCC1's two BRCT motifs in recovery from methylation damage. DNA Repair (Amst.) 2 (2003) 407-415
15. Levy N., Martz A., Bresson A., Spenlehauer C., de Murcia G., and Menissier-de Murcia J. XRCC1 is phosphorylated by DNA-dependent protein kinase in response to DNA damage. Nucl. Acids Res. 34 (2006) 32-41
16. Lindahl T. Instability and decay of the primary structure of DNA. Nature 362 (1993) 709-715
17. Litchfield D.W. Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. Biochem. J. 369 (2003) 1-15
18. Loizou J.I., El-Khamisy S.F., Zlatanou A., Moore D.J., Chan D.W., Qin J., Sarno S., Meggio F., Pinna L.A., and Caldecott K.W. The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks. Cell 117 (2004) 17-28
19. Luo H., Chan D.W., Yang T., Rodriguez M., Chen B.P., Leng M., Mu J.J., Chen D., Songyang Z., Wang Y., and Qin J. A new XRCC1-containing complex and its role in cellular survival of methyl methanesulfonate treatment. Mol. Cell Biol. 24 (2004) 8356-8365
20. Marintchev A., Mullen M.A., Maciejewski M.W., Pan B., Gryk M.R., and Mullen G.P. Solution structure of the single-strand break repair protein XRCC1 N-terminal domain. Nat. Struct. Biol. 6 (1999) 884-893
21. Masson M., Niedergang C., Schreiber V., Muller S., Menissier-de Murcia J., and de Murcia G. XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage. Mol. Cell Biol. 18 (1998) 3563-3571
22. Parsons J.L., Tait P.S., Finch D., Dianova I.I., Allinson S.L., and Dianov G.L. CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins. Mol. Cell 29 (2008) 477-487
23. Schreiber V., Ame J.C., Dolle P., Schultz I., Rinaldi B., Fraulob V., Menissier-de Murcia J., and de Murcia G. Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1. J. Biol. Chem. 277 (2002) 23028-23036
24. Tanaka M., Lai J.S., and Herr W. Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an Snrna and Messenger-Rna promoter. Cell 68 (1992) 755-767
25. Vidal A.E., Boiteux S., Hickson I.D., and Radicella J.P. XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions. EMBO J. 20 (2001) 6530-6539
26. Whitehouse C.J., Taylor R.M., Thistlethwaite A., Zhang H., Karimi-Busheri F., Lasko D.D., Weinfeld M., and Caldecott K.W. XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair. Cell 104 (2001) 107-117