A brief history of brain iron research

Journal of the Neurological Sciences

Volumn 207, Issue 1-2, 2003, Pages 95-97

  Koeppen, Arnulf H ^a  

^a STRATTON VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FERRITIN; FRATAXIN; IRON; MESSENGER RNA; METAL TRANSPORTER PROTEIN 1; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; PROTEIN; TRANSFERRIN; UNCLASSIFIED DRUG;

BRAIN LEVEL; BRAIN REGION; BRAIN TISSUE; CENTRAL NERVOUS SYSTEM DISEASE; CONFERENCE PAPER; HISTORY OF MEDICINE; HUMAN; IMMUNOHISTOCHEMISTRY; IRON OVERLOAD; NONHUMAN; PRIORITY JOURNAL; STAINING; TISSUE SECTION;

ANIMALS; BRAIN; HUMANS; IRON;

EID: 12244269061     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(02)00429-X     Document Type: Conference Paper

References (36)

1. Perls M. Nachweis von Eisenoxyd in gewissen Pigmenten (Demonstration of iron oxide in certain pigments). Virchows Arch. Pathol. Anat. Physiol. Klin. Med. 39:1867;42-48.
2. Nguyen-Legros J., Bizot J., Bolesse M., Pulicani J.-P. «Noir de diaminobenzidine»: Une nouvelle méthode histochimique de revelation du fer exogène. «Diaminobenzidine black»: A new histochemical method for the visualization of exogenous iron Histochemistry. 66:1980;239-244.
3. Hill J.M., Switzer R.C. The regional distribution and cellular localization of iron in the rat brain. Neuroscience. 11:1984;595-603.
4. Zaleski S.S. Das Eisen der Organe beim Morbus maculosus Werlhofii. The iron of the organs in Werlhof's morbus maculosus Arch. Exp. Pathol. Pharmakol. 23:1886;77-90.
5. Diezel B. Iron in the brain: a chemical and histochemical examination. Waelsch H. Biochemistry of the developing nervous system. 1955;145-152 Academic Press, New York.
6. Guizzetti P. Principali resultati dell'applicazione grossolana a fresco delle reazione istochimiche del ferro sul sistema nervoso centrale dell'uomo e di alcuni mammiferi domestici. Principal results of the application of the histochemical reactions for iron to gross fresh tissue of the central nervous system of man and some domestic animals Riv. Patol. Nerv. Ment. 20:1915;103-117.
7. Spatz H. Über den Eisennachweis in Gehirn, besonders in Zentren des extrapyramidal-motorischen Systems. On the visualization of iron in the brain, especially in the centers of the extrapyramidal motor system Z. Ges. Neurol. Psychiatr. 77:1922;261-390.
8. Patino M.M., Walden W.E. Cloning of a functional cDNA for the rabbit ferritin mRNA repressor protein. J. Biol. Chem. 267:1992;19011-19016.
9. Guo B., Yu Y., Leibold E.A. Iron regulates cytoplasmic levels of a novel iron-responsive element binding protein without aconitase activity. J. Biol. Chem. 269:1994;24252-24260.
10. Guo B., Brown F.M., Phillips J.D., Yu Y., Leibold E.A. Characterization and expression of iron regulatory protein 2 (IRP2). J. Biol. Chem. 270:1995;16529-16535.
11. Koeppen A.H., Dickson A.C., Chu R.C., Thach R.E. The pathogenesis of superficial siderosis of the central nervous system. Ann. Neurol. 34:1993;646-653.
12. Bloch B., Popovici T., Levin M.J.et al. Transferrin gene expression visualized in oligodendrocytes of the rat brain by using in situ hybridization and immunohistochemistry. Proc. Nat. Acad. Sci. U. S. A. 82:1985;6706-6710.
13. Dwork A.J., Schon E.A., Herbert J. Nonidentical distribution of transferrin and ferric iron in human brain. Neuroscience. 27:1988;333-345.
14. Koeppen A.H., Dickson A.C., McEvoy J.A. The heterogeneous distribution of brain transferrin. J. Neuropathol. Exp. Neurol. 54:1995;395-403.
15. Jefferies W.A., Brandon M.R., Hunt A.F.et al. Transferrin receptor on endothelium of brain capillaries. Nature. 312:1984;162-163.
16. Kaplan J., Kushner J.P. Mining the genome for iron. Nature. 403:2000;711-713.
17. Moos T., Trinder D., Morgan E.H. Cellular distribution of ferric iron, ferritin, transferrin and divalent metal transporter 1 (DMT1) in substantia nigra and basal ganglia of normal and β-2-microglobulin deficient mouse brain. Cell. Mol. Biol. 46:2000;549-561.
18. Burdo J.R., Menzies S.L., Simpson I.A.et al. Distribution of divalent metal transporter 1 and metal transport protein 1 in the normal and Belgrade rat. J. Neurosci. Res. 66:2001;1198-1207.
19. Campuzano V., Montermini L., Molto M.D.et al. Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion. Science. 271:1996;1423-1427.
20. Cammermeyer J. Deposition of iron in paraventricular areas of the human brain in hemochromatosis. J. Neuropathol. Exp. Neurol. 6:1947;111-127.
21. McDougal D.B., Adams R.D. The neuropathological changes in hemochromatosis. J. Neuropathol. Exp. Neurol. 9:1950;117-118.
22. Dallman P.R., Siimes M.A., Manies E.C. Brain iron: persistent deficiency following short-term iron deprivation in the young rat. Brit. J. Haematol. 31:1975;209-215.
23. Roeser H.P., Lee G.R., Nacht S., Cartwright G.E. The role of ceruloplasmin in iron metabolism. J. Clin. Invest. 49:1970;2408-2417.
24. Harris Z.L., Klomp L.W.J., Gitlin J.D. Aceruloplasminemia: an inherited neurodegenerative disease with impairment of iron homeostasis. Am. J. Clin. Nutr. 67(Suppl.):1998;972S-977S.
25. Brittenham G.M., Weiss G., Brissot P.et al. Clinical consequences of new insights in the pathophysiology of disorders of iron and heme metabolism. Hematology. 2000;39-50. [Am. Soc. Hematol. Ed. Program].
26. Zhou B., Westaway S.K., Levinson B.et al. A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome. Nat. Genet. 28:2001;345-349.
27. Goodman L. Alzheimer's disease. A clinico-pathologic analysis of twenty-three cases with a theory on pathogenesis. J. Nerv. Ment. Dis. 117:1953;97-130.
28. Koeppen A.H., Dentinger M.P. Brain hemosiderin and superficial siderosis of the central nervous system. J. Neuropathol. Exp. Neurol. 47:1988;249-270.
29. Kaneko Y., Kitamoto J., Tateishi J., Yamaguchi K. Ferritin immunohistochemistry as a marker for microglia. Acta Neuropathol. (Berl.). 79:1989;129-136.
30. Hallgren B., Sourander P. The non-haemin iron in the cerebral cortex in Alzheimer's disease. J. Neurochem. 3:1958;41-51.
31. Waldvogel D., van Gelderen P., Hallett M. Increased iron in the dentate nucleus of patients with Friedreich's ataxia. Ann. Neurol. 46:1999;123-125.
32. Koeppen A.H. Neuropathology of the inherited ataxias. Manto M.U., Pandolfo M. The cerebellum and its disorders. 2002;387-405 Cambridge Univ. Press, Cambridge.
33. Puccio H., Simon D., Cossée M.et al. Mouse models of Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits. Nat. Genet. 27:2001;181-186.
34. Morita H., Ikeda S.-I., Yamamoto K.et al. Hereditary ceruloplasmin deficiency with hemosiderosis: a clinicopathological study of a Japanese family. Ann. Neurol. 37:1995;646-656.
35. Kawanami T., Kato T., Daimon M.et al. Hereditary caeruloplasmin deficiency: clinicopathological study of a patient. J. Neurol. Neurosurg. Psychiatr. 61:1996;506-509.
36. Curtis A.R.J., Fey C., Morris C.M.et al. Mutations in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease. Nat. Genet. 28:2001;350-354.