-
1
-
-
0023198005
-
Recombinant human tissue-type plasminogen activator therapy in acute thromboembolic stroke
-
Papadopoulos, S.M.; Chandler, W.F.; Salamat, M.S.; Topol, E.J.; Sackellares, J.C. Recombinant human tissue-type plasminogen activator therapy in acute thromboembolic stroke. J. Neurosurg. 1987, 67, 394-398.
-
(1987)
J. Neurosurg
, vol.67
, pp. 394-398
-
-
Papadopoulos, S.M.1
Chandler, W.F.2
Salamat, M.S.3
Topol, E.J.4
Sackellares, J.C.5
-
2
-
-
84870397199
-
Tissue Plasminogen Activator and Stroke: Review of the Literature for the Clinician
-
Demers, G.; Meurer, W.J.; Shih, R.; Rosenbaum, S.; Vilke, G.M. Tissue Plasminogen Activator and Stroke: Review of the Literature for the Clinician. J. Emerg. Med. 2012, 43, 1149-1154.
-
(2012)
J. Emerg. Med
, vol.43
, pp. 1149-1154
-
-
Demers, G.1
Meurer, W.J.2
Shih, R.3
Rosenbaum, S.4
Vilke, G.M.5
-
3
-
-
49349107361
-
-
World Health Organizition (WHO), Available online, accessed on 9 December
-
World Health Organizition (WHO). The top 10 causes of death. Available online: http://www.who.int/mediacentre/factsheets/fs310/en/index.html (accessed on 9 December 2012).
-
(2012)
The Top 10 Causes of Death
-
-
-
4
-
-
27744548575
-
Ghrelin, the same peptide for different functions: Player or bystander?
-
Lago, F.; Gonzalez-Juanatey, J.R.; Casanueva, F.F.; Gomez-Reino, J.; Dieguez, C.; Gualillo, O. Ghrelin, the same peptide for different functions: Player or bystander? Vitam. Horm. 2005, 71, 405-432.
-
(2005)
Vitam. Horm
, vol.71
, pp. 405-432
-
-
Lago, F.1
Gonzalez-Juanatey, J.R.2
Casanueva, F.F.3
Gomez-Reino, J.4
Dieguez, C.5
Gualillo, O.6
-
5
-
-
0033540056
-
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
-
Kojima, M.; Hosoda, H.; Date, Y.; Nakazato, M.; Matsuo, H.; Kangawa, K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999, 402, 656-660.
-
(1999)
Nature
, vol.402
, pp. 656-660
-
-
Kojima, M.1
Hosoda, H.2
Date, Y.3
Nakazato, M.4
Matsuo, H.5
Kangawa, K.6
-
6
-
-
38849090670
-
Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone
-
Yang, J.; Brown, M.S.; Liang, G.; Grishin, N.V.; Goldstein, J.L. Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. Cell 2008, 132, 387-396.
-
(2008)
Cell
, vol.132
, pp. 387-396
-
-
Yang, J.1
Brown, M.S.2
Liang, G.3
Grishin, N.V.4
Goldstein, J.L.5
-
7
-
-
44049094269
-
Ghrelin octanoylation mediated by an orphan lipid transferase
-
Gutierrez, J.A.; Solenberg, P.J.; Perkins, D.R.; Willency, J.A.; Knierman, M.D.; Jin, Z.; Witcher, D.R.; Luo, S.; Onyia, J.E.; Hale, J.E. Ghrelin octanoylation mediated by an orphan lipid transferase. Proc. Natl. Acad. Sci. USA 2008, 105, 6320-6325.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 6320-6325
-
-
Gutierrez, J.A.1
Solenberg, P.J.2
Perkins, D.R.3
Willency, J.A.4
Knierman, M.D.5
Jin, Z.6
Witcher, D.R.7
Luo, S.8
Onyia, J.E.9
Hale, J.E.10
-
8
-
-
33746739498
-
Ghrelin and the short- and long-term regulation of appetite and body weight
-
Cummings, D.E. Ghrelin and the short- and long-term regulation of appetite and body weight. Physiol. Behav. 2006, 89, 71-84.
-
(2006)
Physiol. Behav
, vol.89
, pp. 71-84
-
-
Cummings, D.E.1
-
9
-
-
0034687376
-
Ghrelin induces adiposity in rodents
-
Tschop, M.; Smiley, D.L.; Heiman, M.L. Ghrelin induces adiposity in rodents. Nature 2000, 407, 908-913.
-
(2000)
Nature
, vol.407
, pp. 908-913
-
-
Tschop, M.1
Smiley, D.L.2
Heiman, M.L.3
-
10
-
-
0037456519
-
The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis
-
Cowley, M.A.; Smith, R.G.; Diano, S.; Tschop, M.; Pronchuk, N.; Grove, K.L.; Strasburger, C.J.; Bidlingmaier, M.; Esterman, M.; Heiman, M.L.; et al. The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron 2003, 37, 649-661.
-
(2003)
Neuron
, vol.37
, pp. 649-661
-
-
Cowley, M.A.1
Smith, R.G.2
Diano, S.3
Tschop, M.4
Pronchuk, N.5
Grove, K.L.6
Strasburger, C.J.7
Bidlingmaier, M.8
Esterman, M.9
Heiman, M.L.10
-
11
-
-
79951682389
-
Metabolic status regulates ghrelin function on energy homeostasis
-
Briggs, D.I.; Andrews, Z.B. Metabolic status regulates ghrelin function on energy homeostasis. Neuroendocrinology 2011, 93, 48-57.
-
(2011)
Neuroendocrinology
, vol.93
, pp. 48-57
-
-
Briggs, D.I.1
Andrews, Z.B.2
-
12
-
-
81755172024
-
Central mechanisms involved in the orexigenic actions of ghrelin
-
Andrews, Z.B. Central mechanisms involved in the orexigenic actions of ghrelin. Peptides 2011, 32, 2248-2255.
-
(2011)
Peptides
, vol.32
, pp. 2248-2255
-
-
Andrews, Z.B.1
-
13
-
-
33748560432
-
Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite
-
Abizaid, A.; Liu, Z.W.; Andrews, Z.B.; Shanabrough, M.; Borok, E.; Elsworth, J.D.; Roth, R.H.; Sleeman, M.W.; Picciotto, M.R.; Tschop, M.H.; et al. Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite. J. Clin. Invest. 2006, 116, 3229-3239.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 3229-3239
-
-
Abizaid, A.1
Liu, Z.W.2
Andrews, Z.B.3
Shanabrough, M.4
Borok, E.5
Elsworth, J.D.6
Roth, R.H.7
Sleeman, M.W.8
Picciotto, M.R.9
Tschop, M.H.10
-
14
-
-
27744593324
-
Ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens
-
Naleid, A.M.; Grace, M.K.; Cummings, D.E.; Levine, A.S. Ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens. Peptides 2005, 26, 2274-2279.
-
(2005)
Peptides
, vol.26
, pp. 2274-2279
-
-
Naleid, A.M.1
Grace, M.K.2
Cummings, D.E.3
Levine, A.S.4
-
15
-
-
33344479006
-
Ghrelin controls hippocampal spine synapse density and memory performance
-
Diano, S.; Farr, S.A.; Benoit, S.C.; McNay, E.C.; da Silva, I.; Horvath, B.; Gaskin, F.S.; Nonaka, N.; Jaeger, L.B.; Banks, W.A.; et al. Ghrelin controls hippocampal spine synapse density and memory performance. Nat. Neurosci. 2006, 9, 381-388.
-
(2006)
Nat. Neurosci
, vol.9
, pp. 381-388
-
-
Diano, S.1
Farr, S.A.2
Benoit, S.C.3
McNay, E.C.4
da Silva, I.5
Horvath, B.6
Gaskin, F.S.7
Nonaka, N.8
Jaeger, L.B.9
Banks, W.A.10
-
16
-
-
84865205876
-
Ghrelin regulates the hypothalamic-pituitary-adrenal axis and restricts anxiety after acute stress
-
Spencer, S.J.; Xu, L.; Clarke, M.A.; Lemus, M.; Reichenbach, A.; Geenen, B.; Kozicz, T.; Andrews, Z.B. Ghrelin regulates the hypothalamic-pituitary-adrenal axis and restricts anxiety after acute stress. Biol. Psychiatry 2012, 72, 457-465.
-
(2012)
Biol. Psychiatry
, vol.72
, pp. 457-465
-
-
Spencer, S.J.1
Xu, L.2
Clarke, M.A.3
Lemus, M.4
Reichenbach, A.5
Geenen, B.6
Kozicz, T.7
Andrews, Z.B.8
-
17
-
-
46049083776
-
The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress
-
Lutter, M.; Sakata, I.; Osborne-Lawrence, S.; Rovinsky, S.A.; Anderson, J.G.; Jung, S.; Birnbaum, S.; Yanagisawa, M.; Elmquist, J.K.; Nestler, E.J.; Zigman, J.M. The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress. Nat. Neurosci. 2008, 11, 752-753.
-
(2008)
Nat. Neurosci
, vol.11
, pp. 752-753
-
-
Lutter, M.1
Sakata, I.2
Osborne-Lawrence, S.3
Rovinsky, S.A.4
Anderson, J.G.5
Jung, S.6
Birnbaum, S.7
Yanagisawa, M.8
Elmquist, J.K.9
Nestler, E.J.10
Zigman, J.M.11
-
18
-
-
15544385058
-
Ghrelin: Structure and function
-
Kojima, M.; Kangawa, K. Ghrelin: Structure and function. Physiol. Rev. 2005, 85, 495-522.
-
(2005)
Physiol. Rev
, vol.85
, pp. 495-522
-
-
Kojima, M.1
Kangawa, K.2
-
19
-
-
0030762351
-
Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues
-
Guan, X.M.; Yu, H.; Palyha, O.C.; McKee, K.K.; Feighner, S.D.; Sirinathsinghji, D.J.; Smith, R.G.; van der Ploeg, L.H.; Howard, A.D. Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues. Brain Res. Mol. Brain Res. 1997, 48, 23-29.
-
(1997)
Brain Res. Mol. Brain Res
, vol.48
, pp. 23-29
-
-
Guan, X.M.1
Yu, H.2
Palyha, O.C.3
McKee, K.K.4
Feighner, S.D.5
Sirinathsinghji, D.J.6
Smith, R.G.7
van der Ploeg, L.H.8
Howard, A.D.9
-
20
-
-
40349098110
-
Insulin regulation of growth hormone receptor gene expression: Involvement of both the PI-3 kinase and MEK/ERK signaling pathways
-
Bennett, W.L.; Keeton, A.B.; Ji, S.; Xu, J.; Messina, J.L. Insulin regulation of growth hormone receptor gene expression: Involvement of both the PI-3 kinase and MEK/ERK signaling pathways. Endocrine 2007, 32, 219-226.
-
(2007)
Endocrine
, vol.32
, pp. 219-226
-
-
Bennett, W.L.1
Keeton, A.B.2
Ji, S.3
Xu, J.4
Messina, J.L.5
-
21
-
-
29044434688
-
Expression of ghrelin receptor mRNA in the rat and the mouse brain
-
Zigman, J.M.; Jones, J.E.; Lee, C.E.; Saper, C.B.; Elmquist, J.K. Expression of ghrelin receptor mRNA in the rat and the mouse brain. J. Comp. Neurol. 2006, 494, 528-548.
-
(2006)
J. Comp. Neurol
, vol.494
, pp. 528-548
-
-
Zigman, J.M.1
Jones, J.E.2
Lee, C.E.3
Saper, C.B.4
Elmquist, J.K.5
-
22
-
-
0035843183
-
A role for ghrelin in the central regulation of feeding
-
Nakazato, M.; Murakami, N.; Date, Y.; Kojima, M.; Matsuo, H.; Kangawa, K.; Matsukura, S. A role for ghrelin in the central regulation of feeding. Nature 2001, 409, 194-198.
-
(2001)
Nature
, vol.409
, pp. 194-198
-
-
Nakazato, M.1
Murakami, N.2
Date, Y.3
Kojima, M.4
Matsuo, H.5
Kangawa, K.6
Matsukura, S.7
-
23
-
-
33644863678
-
Cell biology of the ghrelin receptor
-
Camina, J.P. Cell biology of the ghrelin receptor. J. Neuroendocrinol. 2006, 18, 65-76.
-
(2006)
J. Neuroendocrinol
, vol.18
, pp. 65-76
-
-
Camina, J.P.1
-
24
-
-
9444246501
-
A receptor in pituitary and hypothalamus that functions in growth hormone release
-
Howard, A.D.; Feighner, S.D.; Cully, D.F.; Arena, J.P.; Liberator, P.A.; Rosenblum, C.I.; Hamelin, M.; Hreniuk, D.L.; Palyha, O.C.; Anderson, J.; et al. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science 1996, 273, 974-977.
-
(1996)
Science
, vol.273
, pp. 974-977
-
-
Howard, A.D.1
Feighner, S.D.2
Cully, D.F.3
Arena, J.P.4
Liberator, P.A.5
Rosenblum, C.I.6
Hamelin, M.7
Hreniuk, D.L.8
Palyha, O.C.9
Anderson, J.10
-
25
-
-
0031003664
-
Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors
-
McKee, K.K.; Palyha, O.C.; Feighner, S.D.; Hreniuk, D.L.; Tan, C.P.; Phillips, M.S.; Smith, R.G.; van der Ploeg, L.H.; Howard, A.D. Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors. Mol. Endocrinol. 1997, 11, 415-423.
-
(1997)
Mol. Endocrinol
, vol.11
, pp. 415-423
-
-
McKee, K.K.1
Palyha, O.C.2
Feighner, S.D.3
Hreniuk, D.L.4
Tan, C.P.5
Phillips, M.S.6
Smith, R.G.7
van der Ploeg, L.H.8
Howard, A.D.9
-
26
-
-
70350291952
-
In vivo characterization of high Basal signaling from the ghrelin receptor
-
Petersen, P.S.; Woldbye, D.P.; Madsen, A.N.; Egerod, K.L.; Jin, C.; Lang, M.; Rasmussen, M.; Beck-Sickinger, A.G.; Holst, B. In vivo characterization of high Basal signaling from the ghrelin receptor. Endocrinology 2009, 150, 4920-4930.
-
(2009)
Endocrinology
, vol.150
, pp. 4920-4930
-
-
Petersen, P.S.1
Woldbye, D.P.2
Madsen, A.N.3
Egerod, K.L.4
Jin, C.5
Lang, M.6
Rasmussen, M.7
Beck-Sickinger, A.G.8
Holst, B.9
-
27
-
-
84863010954
-
Apo-ghrelin receptor forms heteromers with DRD2 in hypothalamic neurons and is essential for anorexigenic effects of DRD2 agonism
-
Kern, A.; Albarran-Zeckler, R.; Walsh, H.E.; Smith, R.G. Apo-ghrelin receptor forms heteromers with DRD2 in hypothalamic neurons and is essential for anorexigenic effects of DRD2 agonism. Neuron 2012, 73, 317-332.
-
(2012)
Neuron
, vol.73
, pp. 317-332
-
-
Kern, A.1
Albarran-Zeckler, R.2
Walsh, H.E.3
Smith, R.G.4
-
28
-
-
80655149447
-
Mutually opposite signal modulation by hypothalamic heterodimerization of ghrelin and melanocortin-3 receptors
-
Rediger, A.; Piechowski, C.L.; Yi, C.X.; Tarnow, P.; Strotmann, R.; Gruters, A.; Krude, H.; Schoneberg, T.; Tschop, M.H.; Kleinau, G.; Biebermann, H. Mutually opposite signal modulation by hypothalamic heterodimerization of ghrelin and melanocortin-3 receptors. J. Biol. Chem. 2011, 286, 39623-39631.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 39623-39631
-
-
Rediger, A.1
Piechowski, C.L.2
Yi, C.X.3
Tarnow, P.4
Strotmann, R.5
Gruters, A.6
Krude, H.7
Schoneberg, T.8
Tschop, M.H.9
Kleinau, G.10
Biebermann, H.11
-
29
-
-
0036073405
-
Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure
-
Banks, W.A.; Tschop, M.; Robinson, S.M.; Heiman, M.L. Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure. J. Pharmacol. Exp. Ther. 2002, 302, 822-827.
-
(2002)
J. Pharmacol. Exp. Ther
, vol.302
, pp. 822-827
-
-
Banks, W.A.1
Tschop, M.2
Robinson, S.M.3
Heiman, M.L.4
-
30
-
-
0037066587
-
Neuroendocrine and peripheral activities of ghrelin: Implications in metabolism and obesity
-
Muccioli, G.; Tschop, M.; Papotti, M.; Deghenghi, R.; Heiman, M.; Ghigo, E. Neuroendocrine and peripheral activities of ghrelin: Implications in metabolism and obesity. Eur. J. Pharmacol. 2002, 440, 235-254.
-
(2002)
Eur. J. Pharmacol
, vol.440
, pp. 235-254
-
-
Muccioli, G.1
Tschop, M.2
Papotti, M.3
Deghenghi, R.4
Heiman, M.5
Ghigo, E.6
-
31
-
-
0037164747
-
Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT
-
Baldanzi, G.; Filigheddu, N.; Cutrupi, S.; Catapano, F.; Bonissoni, S.; Fubini, A.; Malan, D.; Baj, G.; Granata, R.; Broglio, F.; et al. Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT. J. Cell Biol. 2002, 159, 1029-1037.
-
(2002)
J. Cell Biol
, vol.159
, pp. 1029-1037
-
-
Baldanzi, G.1
Filigheddu, N.2
Cutrupi, S.3
Catapano, F.4
Bonissoni, S.5
Fubini, A.6
Malan, D.7
Baj, G.8
Granata, R.9
Broglio, F.10
-
32
-
-
1642581469
-
Protective effects of ghrelin on ischemia/reperfusion injury in the isolated rat heart
-
Chang, L.; Ren, Y.; Liu, X.; Li, W.G.; Yang, J.; Geng, B.; Weintraub, N.L.; Tang, C. Protective effects of ghrelin on ischemia/reperfusion injury in the isolated rat heart. J. Cardiovasc. Pharmacol. 2004, 43, 165-170.
-
(2004)
J. Cardiovasc. Pharmacol
, vol.43
, pp. 165-170
-
-
Chang, L.1
Ren, Y.2
Liu, X.3
Li, W.G.4
Yang, J.5
Geng, B.6
Weintraub, N.L.7
Tang, C.8
-
33
-
-
0242383502
-
Effect of ghrelin and synthetic growth hormone secretagogues in normal and ischemic rat heart
-
Frascarelli, S.; Ghelardoni, S.; Ronca-Testoni, S.; Zucchi, R. Effect of ghrelin and synthetic growth hormone secretagogues in normal and ischemic rat heart. Basic Res. Cardiol. 2003, 98, 401-405.
-
(2003)
Basic Res. Cardiol
, vol.98
, pp. 401-405
-
-
Frascarelli, S.1
Ghelardoni, S.2
Ronca-Testoni, S.3
Zucchi, R.4
-
34
-
-
78650743194
-
The extra-hypothalamic actions of ghrelin on neuronal function
-
Andrews, Z.B. The extra-hypothalamic actions of ghrelin on neuronal function. Trends Neurosci. 2010, 34, 31-40.
-
(2010)
Trends Neurosci
, vol.34
, pp. 31-40
-
-
Andrews, Z.B.1
-
35
-
-
47349087292
-
Ghrelin antagonizes MPTP-induced neurotoxicity to the dopaminergic neurons in mouse substantia nigra
-
Jiang, H.; Li, L.J.; Wang, J.; Xie, J.X. Ghrelin antagonizes MPTP-induced neurotoxicity to the dopaminergic neurons in mouse substantia nigra. Exp. Neurol. 2008, 212, 532-537.
-
(2008)
Exp. Neurol
, vol.212
, pp. 532-537
-
-
Jiang, H.1
Li, L.J.2
Wang, J.3
Xie, J.X.4
-
36
-
-
70449673061
-
Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism
-
Andrews, Z.B.; Erion, D.; Beiler, R.; Liu, Z.W.; Abizaid, A.; Zigman, J.; Elsworth, J.D.; Savitt, J.M.; DiMarchi, R.; Tschoep, M.; et al. Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism. J. Neurosci. 2009, 29, 14057-14065.
-
(2009)
J. Neurosci
, vol.29
, pp. 14057-14065
-
-
Andrews, Z.B.1
Erion, D.2
Beiler, R.3
Liu, Z.W.4
Abizaid, A.5
Zigman, J.6
Elsworth, J.D.7
Savitt, J.M.8
Dimarchi, R.9
Tschoep, M.10
-
37
-
-
70449527787
-
Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation
-
Moon, M.; Kim, H.G.; Hwang, L.; Seo, J.H.; Kim, S.; Hwang, S.; Lee, D.; Chung, H.; Oh, M.S.; Lee, K.T.; Park, S. Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation. Neurotox. Res. 2009, 15, 332-347.
-
(2009)
Neurotox. Res
, vol.15
, pp. 332-347
-
-
Moon, M.1
Kim, H.G.2
Hwang, L.3
Seo, J.H.4
Kim, S.5
Hwang, S.6
Lee, D.7
Chung, H.8
Oh, M.S.9
Lee, K.T.10
Park, S.11
-
38
-
-
79959846783
-
Postprandial ghrelin response is reduced in patients with Parkinson's disease and idiopathic REM sleep behaviour disorder: A peripheral biomarker for early Parkinson's disease?
-
Unger, M.M.; Moller, J.C.; Mankel, K.; Eggert, K.M.; Bohne, K.; Bodden, M.; Stiasny-Kolster, K.; Kann, P.H.; Mayer, G.; Tebbe, J.J.; Oertel, W.H. Postprandial ghrelin response is reduced in patients with Parkinson's disease and idiopathic REM sleep behaviour disorder: A peripheral biomarker for early Parkinson's disease? J. Neurol. 2011, 258, 982-990.
-
(2011)
J. Neurol
, vol.258
, pp. 982-990
-
-
Unger, M.M.1
Moller, J.C.2
Mankel, K.3
Eggert, K.M.4
Bohne, K.5
Bodden, M.6
Stiasny-Kolster, K.7
Kann, P.H.8
Mayer, G.9
Tebbe, J.J.10
Oertel, W.H.11
-
39
-
-
33745713317
-
Plasma levels of neuropeptides in Alzheimer's disease
-
Proto, C.; Romualdi, D.; Cento, R.M.; Spada, R.S.; Di Mento, G.; Ferri, R.; Lanzone, A. Plasma levels of neuropeptides in Alzheimer's disease. Gynecol. Endocrinol. 2006, 22, 213-218.
-
(2006)
Gynecol. Endocrinol
, vol.22
, pp. 213-218
-
-
Proto, C.1
Romualdi, D.2
Cento, R.M.3
Spada, R.S.4
Di Mento, G.5
Ferri, R.6
Lanzone, A.7
-
40
-
-
78650637671
-
Expression of the ghrelin and neurotensin systems is altered in the temporal lobe of Alzheimer's disease patients
-
Gahete, M.D.; Rubio, A.; Cordoba-Chacon, J.; Gracia-Navarro, F.; Kineman, R.D.; Avila, J.; Luque, R.M.; Castano, J.P. Expression of the ghrelin and neurotensin systems is altered in the temporal lobe of Alzheimer's disease patients. J. Alzheimers Dis. 2010, 22, 819-828.
-
(2010)
J. Alzheimers Dis
, vol.22
, pp. 819-828
-
-
Gahete, M.D.1
Rubio, A.2
Cordoba-Chacon, J.3
Gracia-Navarro, F.4
Kineman, R.D.5
Avila, J.6
Luque, R.M.7
Castano, J.P.8
-
41
-
-
78651359641
-
Ghrelin ameliorates cognitive dysfunction and neurodegeneration in intrahippocampal amyloid-beta1-42 oligomer-injected mice
-
Moon, M.; Choi, J.G.; Nam, D.W.; Hong, H.S.; Choi, Y.J.; Oh, M.S.; Mook-Jung, I. Ghrelin ameliorates cognitive dysfunction and neurodegeneration in intrahippocampal amyloid-beta1-42 oligomer-injected mice. J. Alzheimers Dis. 2011, 23, 147-159.
-
(2011)
J. Alzheimers Dis
, vol.23
, pp. 147-159
-
-
Moon, M.1
Choi, J.G.2
Nam, D.W.3
Hong, H.S.4
Choi, Y.J.5
Oh, M.S.6
Mook-Jung, I.7
-
42
-
-
77954470483
-
Ghrelin modulates insulin sensitivity and tau phosphorylation in high glucose-induced hippocampal neurons
-
Chen, Y.; Cao, C.P.; Li, C.R.; Wang, W.; Zhang, D.; Han, L.L.; Zhang, X.Q.; Kim, A.; Kim, S.; Liu, G.L. Ghrelin modulates insulin sensitivity and tau phosphorylation in high glucose-induced hippocampal neurons. Biol. Pharm. Bull. 2010, 33, 1165-1169.
-
(2010)
Biol. Pharm. Bull
, vol.33
, pp. 1165-1169
-
-
Chen, Y.1
Cao, C.P.2
Li, C.R.3
Wang, W.4
Zhang, D.5
Han, L.L.6
Zhang, X.Q.7
Kim, A.8
Kim, S.9
Liu, G.L.10
-
43
-
-
26844433631
-
Growth hormone-releasing peptide hexarelin reduces neonatal brain injury and alters Akt/glycogen synthase kinase-3beta phosphorylation
-
Brywe, K.G.; Leverin, A.L.; Gustavsson, M.; Mallard, C.; Granata, R.; Destefanis, S.; Volante, M.; Hagberg, H.; Ghigo, E.; Isgaard, J. Growth hormone-releasing peptide hexarelin reduces neonatal brain injury and alters Akt/glycogen synthase kinase-3beta phosphorylation. Endocrinology 2005, 146, 4665-4672.
-
(2005)
Endocrinology
, vol.146
, pp. 4665-4672
-
-
Brywe, K.G.1
Leverin, A.L.2
Gustavsson, M.3
Mallard, C.4
Granata, R.5
Destefanis, S.6
Volante, M.7
Hagberg, H.8
Ghigo, E.9
Isgaard, J.10
-
44
-
-
33947513078
-
Ghrelin reduces injury of hippocampal neurons in a rat model of cerebral ischemia/reperfusion
-
Liu, Y.; Wang, P.S.; Xie, D.; Liu, K.; Chen, L. Ghrelin reduces injury of hippocampal neurons in a rat model of cerebral ischemia/reperfusion. Chin. J. Physiol. 2006, 49, 244-250.
-
(2006)
Chin. J. Physiol
, vol.49
, pp. 244-250
-
-
Liu, Y.1
Wang, P.S.2
Xie, D.3
Liu, K.4
Chen, L.5
-
45
-
-
34250205262
-
Ghrelin protects cortical neuron against focal ischemia/reperfusion in rats
-
Miao, Y.; Xia, Q.; Hou, Z.; Zheng, Y.; Pan, H.; Zhu, S. Ghrelin protects cortical neuron against focal ischemia/reperfusion in rats. Biochem. Biophys. Res. Commun. 2007, 359, 795-800.
-
(2007)
Biochem. Biophys. Res. Commun
, vol.359
, pp. 795-800
-
-
Miao, Y.1
Xia, Q.2
Hou, Z.3
Zheng, Y.4
Pan, H.5
Zhu, S.6
-
46
-
-
79952157408
-
Ghrelin suppresses inflammation and neuronal nitric oxide synthase in focal cerebral ischemia via the vagus nerve
-
Cheyuo, C.; Wu, R.; Zhou, M.; Jacob, A.; Coppa, G.; Wang, P. Ghrelin suppresses inflammation and neuronal nitric oxide synthase in focal cerebral ischemia via the vagus nerve. Shock 2011, 35, 258-265.
-
(2011)
Shock
, vol.35
, pp. 258-265
-
-
Cheyuo, C.1
Wu, R.2
Zhou, M.3
Jacob, A.4
Coppa, G.5
Wang, P.6
-
47
-
-
84857438430
-
Leptin, adiponectin and ghrelin, new potential mediators of ischemic stroke
-
Kantorova, E.; Chomova, M.; Kurca, E.; Sivak, S.; Zelenak, K.; Kucera, P.; Galajda, P. Leptin, adiponectin and ghrelin, new potential mediators of ischemic stroke. Neuro Endocrinol. Lett. 2011, 32, 716-721.
-
(2011)
Neuro Endocrinol. Lett
, vol.32
, pp. 716-721
-
-
Kantorova, E.1
Chomova, M.2
Kurca, E.3
Sivak, S.4
Zelenak, K.5
Kucera, P.6
Galajda, P.7
-
48
-
-
80052502402
-
Death and survival of neuronal and astrocytic cells in ischemic brain injury: A role of autophagy
-
Xu, M.; Zhang, H.L. Death and survival of neuronal and astrocytic cells in ischemic brain injury: A role of autophagy. Acta Pharmacol. Sin. 2011, 32, 1089-1099.
-
(2011)
Acta Pharmacol. Sin
, vol.32
, pp. 1089-1099
-
-
Xu, M.1
Zhang, H.L.2
-
49
-
-
65549098614
-
Apoptotic mechanisms after cerebral ischemia
-
Broughton, B.R.; Reutens, D.C.; Sobey, C.G. Apoptotic mechanisms after cerebral ischemia. Stroke 2009, 40, e331-e339.
-
(2009)
Stroke
, vol.40
-
-
Broughton, B.R.1
Reutens, D.C.2
Sobey, C.G.3
-
50
-
-
84878594028
-
Transient Global Cerebral Ischemia Produces Morphologically Necrotic, Not Apoptotic Neurons
-
Fujikawa, D.G., Ed.; Springer Science + Business Media: Berlin, Germany
-
Colbourne, F.; Auer, R.N. Transient Global Cerebral Ischemia Produces Morphologically Necrotic, Not Apoptotic Neurons. In Acute Neuronal Injury: The Role of Excitotoxic Programmed Cell Death Mechanisms; Fujikawa, D.G., Ed.; Springer Science + Business Media: Berlin, Germany, 2010.
-
(2010)
Acute Neuronal Injury: The Role of Excitotoxic Programmed Cell Death Mechanisms
-
-
Colbourne, F.1
Auer, R.N.2
-
51
-
-
56349126024
-
Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury
-
Carloni, S.; Buonocore, G.; Balduini, W. Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury. Neurobiol. Dis. 2008, 32, 329-339.
-
(2008)
Neurobiol. Dis
, vol.32
, pp. 329-339
-
-
Carloni, S.1
Buonocore, G.2
Balduini, W.3
-
52
-
-
0035052664
-
Evidence for the involvement of Par-4 in ischemic neuron cell death
-
Culmsee, C.; Zhu, Y.; Krieglstein, J.; Mattson, M.P. Evidence for the involvement of Par-4 in ischemic neuron cell death. J. Cereb. Blood Flow Metab. 2001, 21, 334-343.
-
(2001)
J. Cereb. Blood Flow Metab
, vol.21
, pp. 334-343
-
-
Culmsee, C.1
Zhu, Y.2
Krieglstein, J.3
Mattson, M.P.4
-
53
-
-
0035039678
-
A structural view of mitochondria-mediated apoptosis
-
Shi, Y. A structural view of mitochondria-mediated apoptosis. Nat. Struct. Biol. 2001, 8, 394-401.
-
(2001)
Nat. Struct. Biol
, vol.8
, pp. 394-401
-
-
Shi, Y.1
-
54
-
-
0032544564
-
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
-
Yoshida, H.; Kong, Y.Y.; Yoshida, R.; Elia, A.J.; Hakem, A.; Hakem, R.; Penninger, J.M.; Mak, T.W. Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell 1998, 94, 739-750.
-
(1998)
Cell
, vol.94
, pp. 739-750
-
-
Yoshida, H.1
Kong, Y.Y.2
Yoshida, R.3
Elia, A.J.4
Hakem, A.5
Hakem, R.6
Penninger, J.M.7
Mak, T.W.8
-
55
-
-
0032510758
-
Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
-
Offen, D.; Beart, P.M.; Cheung, N.S.; Pascoe, C.J.; Hochman, A.; Gorodin, S.; Melamed, E.; Bernard, R.; Bernard, O. Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. Proc. Natl. Acad. Sci. USA 1998, 95, 5789-5794.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 5789-5794
-
-
Offen, D.1
Beart, P.M.2
Cheung, N.S.3
Pascoe, C.J.4
Hochman, A.5
Gorodin, S.6
Melamed, E.7
Bernard, R.8
Bernard, O.9
-
56
-
-
53349175016
-
Phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3 beta and ERK1/2 pathways mediate protective effects of acylated and unacylated ghrelin against oxygen-glucose deprivation-induced apoptosis in primary rat cortical neuronal cells
-
Chung, H.; Seo, S.; Moon, M.; Park, S. Phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3 beta and ERK1/2 pathways mediate protective effects of acylated and unacylated ghrelin against oxygen-glucose deprivation-induced apoptosis in primary rat cortical neuronal cells. J. Endocrinol. 2008, 198, 511-521.
-
(2008)
J. Endocrinol
, vol.198
, pp. 511-521
-
-
Chung, H.1
Seo, S.2
Moon, M.3
Park, S.4
-
57
-
-
49649122302
-
UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals
-
Andrews, Z.B.; Liu, Z.W.; Walllingford, N.; Erion, D.M.; Borok, E.; Friedman, J.M.; Tschop, M.H.; Shanabrough, M.; Cline, G.; Shulman, G.I.; et al. UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals. Nature 2008, 454, 846-851.
-
(2008)
Nature
, vol.454
, pp. 846-851
-
-
Andrews, Z.B.1
Liu, Z.W.2
Walllingford, N.3
Erion, D.M.4
Borok, E.5
Friedman, J.M.6
Tschop, M.H.7
Shanabrough, M.8
Cline, G.9
Shulman, G.I.10
-
58
-
-
84869508865
-
Early ghrelin treatment attenuates disruption of the blood brain barrier and apoptosis after traumatic brain injury through a UCP-2 mechanism
-
Lopez, N.E.; Gaston, L.; Lopez, K.R.; Coimbra, R.C.; Hageny, A.; Putnam, J.; Eliceiri, B.; Coimbra, R.; Bansal, V. Early ghrelin treatment attenuates disruption of the blood brain barrier and apoptosis after traumatic brain injury through a UCP-2 mechanism. Brain Res. 2012, 1489, 140-148.
-
(2012)
Brain Res
, vol.1489
, pp. 140-148
-
-
Lopez, N.E.1
Gaston, L.2
Lopez, K.R.3
Coimbra, R.C.4
Hageny, A.5
Putnam, J.6
Eliceiri, B.7
Coimbra, R.8
Bansal, V.9
-
59
-
-
68449105015
-
Neuroprotective effect of ghrelin is associated with decreased expression of prostate apoptosis response-4
-
Hwang, S.; Moon, M.; Kim, S.; Hwang, L.; Ahn, K.J.; Park, S. Neuroprotective effect of ghrelin is associated with decreased expression of prostate apoptosis response-4. Endocrine J. 2009, 56, 609-617.
-
(2009)
Endocrine J
, vol.56
, pp. 609-617
-
-
Hwang, S.1
Moon, M.2
Kim, S.3
Hwang, L.4
Ahn, K.J.5
Park, S.6
-
60
-
-
79958034644
-
Ghrelin suppresses tunicamycinor thapsigargin-triggered endoplasmic reticulum stress-mediated apoptosis in primary cultured rat cortical neuronal cells
-
Chung, H.; Chung, H.Y.; Bae, C.W.; Kim, C.J.; Park, S. Ghrelin suppresses tunicamycinor thapsigargin-triggered endoplasmic reticulum stress-mediated apoptosis in primary cultured rat cortical neuronal cells. Endocrine J. 2011, 58, 409-420.
-
(2011)
Endocrine J
, vol.58
, pp. 409-420
-
-
Chung, H.1
Chung, H.Y.2
Bae, C.W.3
Kim, C.J.4
Park, S.5
-
61
-
-
81855161546
-
Ghrelin prevents neuronal apoptosis and cognitive impairments in sepsis-associated encephalopathy
-
Wang, G.; Wang, W.; Zhao, J.; Ni, Y.; Zhou, X.; Zhang, W. Ghrelin prevents neuronal apoptosis and cognitive impairments in sepsis-associated encephalopathy. Neuroreport 2011, 22, 959-964.
-
(2011)
Neuroreport
, vol.22
, pp. 959-964
-
-
Wang, G.1
Wang, W.2
Zhao, J.3
Ni, Y.4
Zhou, X.5
Zhang, W.6
-
62
-
-
33845910446
-
Ghrelin inhibits apoptosis in hypothalamic neuronal cells during oxygen-glucose deprivation
-
Chung, H.; Kim, E.; Lee, D.H.; Seo, S.; Ju, S.; Lee, D.; Kim, H.; Park, S. Ghrelin inhibits apoptosis in hypothalamic neuronal cells during oxygen-glucose deprivation. Endocrinology 2007, 148, 148-159.
-
(2007)
Endocrinology
, vol.148
, pp. 148-159
-
-
Chung, H.1
Kim, E.2
Lee, D.H.3
Seo, S.4
Ju, S.5
Lee, D.6
Kim, H.7
Park, S.8
-
63
-
-
84856479437
-
Ghrelin protects musculocutaneous tissue from ischemic necrosis by improving microvascular perfusion
-
Rezaeian, F.; Wettstein, R.; Scheuer, C.; Baumker, K.; Bachle, A.; Vollmar, B.; Menger, M.D.; Harder, Y. Ghrelin protects musculocutaneous tissue from ischemic necrosis by improving microvascular perfusion. Am. J. Physiol. Heart Circ. Physiol. 2012, 302, H603-H610.
-
(2012)
Am. J. Physiol. Heart Circ. Physiol
, vol.302
-
-
Rezaeian, F.1
Wettstein, R.2
Scheuer, C.3
Baumker, K.4
Bachle, A.5
Vollmar, B.6
Menger, M.D.7
Harder, Y.8
-
64
-
-
84868695895
-
Ghrelin protects against cobalt chloride-induced hypoxic injury in cardiac H9c2 cells by inhibiting oxidative stress and inducing autophagy
-
Tong, X.X.; Wu, D.; Wang, X.; Chen, H.L.; Chen, J.X.; Wang, X.X.; Wang, X.L.; Gan, L.; Guo, Z.Y.; Shi, G.X.; et al. Ghrelin protects against cobalt chloride-induced hypoxic injury in cardiac H9c2 cells by inhibiting oxidative stress and inducing autophagy. Peptides 2012, 38, 217-337.
-
(2012)
Peptides
, vol.38
, pp. 217-337
-
-
Tong, X.X.1
Wu, D.2
Wang, X.3
Chen, H.L.4
Chen, J.X.5
Wang, X.X.6
Wang, X.L.7
Gan, L.8
Guo, Z.Y.9
Shi, G.X.10
-
65
-
-
84864990336
-
Acute effect of ghrelin on ischemia/reperfusion injury in the rat spinal cord
-
Zhang, Q.; Huang, C.; Meng, B.; Tang, T.; Shi, Q.; Yang, H. Acute effect of ghrelin on ischemia/reperfusion injury in the rat spinal cord. Int. J. Mol. Sci. 2012, 13, 9864-9876.
-
(2012)
Int. J. Mol. Sci
, vol.13
, pp. 9864-9876
-
-
Zhang, Q.1
Huang, C.2
Meng, B.3
Tang, T.4
Shi, Q.5
Yang, H.6
-
66
-
-
33847644971
-
The inflammatory response in stroke
-
Wang, Q.; Tang, X.N.; Yenari, M.A. The inflammatory response in stroke. J. Neuroimmunol. 2007, 184, 53-68.
-
(2007)
J. Neuroimmunol
, vol.184
, pp. 53-68
-
-
Wang, Q.1
Tang, X.N.2
Yenari, M.A.3
-
67
-
-
0029692418
-
Significance of the inflammatory response in brain ischemia
-
Hallenbeck, J.M. Significance of the inflammatory response in brain ischemia. Acta Neurochir. Suppl. 1996, 66, 27-31.
-
(1996)
Acta Neurochir. Suppl
, vol.66
, pp. 27-31
-
-
Hallenbeck, J.M.1
-
68
-
-
0029121104
-
Microglia as a unique cellular target in the treatment of stroke: Potential neurotoxic mediators produced by activated microglia
-
Wood, P.L. Microglia as a unique cellular target in the treatment of stroke: Potential neurotoxic mediators produced by activated microglia. Neurol. Res. 1995, 17, 242-248.
-
(1995)
Neurol. Res
, vol.17
, pp. 242-248
-
-
Wood, P.L.1
-
69
-
-
0034726019
-
Protective effect of microglial conditioning medium on neuronal damage induced by glutamate
-
Watanabe, H.; Abe, H.; Takeuchi, S.; Tanaka, R. Protective effect of microglial conditioning medium on neuronal damage induced by glutamate. Neurosci. Lett. 2000, 289, 53-56.
-
(2000)
Neurosci. Lett
, vol.289
, pp. 53-56
-
-
Watanabe, H.1
Abe, H.2
Takeuchi, S.3
Tanaka, R.4
-
70
-
-
26444572289
-
Ghrelin improves tissue perfusion in severe sepsis via downregulation of endothelin-1
-
Wu, R.; Dong, W.; Zhou, M.; Cui, X.; Hank Simms, H.; Wang, P. Ghrelin improves tissue perfusion in severe sepsis via downregulation of endothelin-1. Cardiovasc. Res. 2005, 68, 318-326.
-
(2005)
Cardiovasc. Res
, vol.68
, pp. 318-326
-
-
Wu, R.1
Dong, W.2
Zhou, M.3
Cui, X.4
Hank, S.H.5
Wang, P.6
-
71
-
-
84878619468
-
Administration of ghrelin improves inflammation, oxidative stress, and apoptosis during and after non-alcoholic fatty liver disease development
-
doi:10.1007/s12020-012-9761-5
-
Li, Y.; Hai, J.; Li, L.; Chen, X.; Peng, H.; Cao, M.; Zhang, Q. Administration of ghrelin improves inflammation, oxidative stress, and apoptosis during and after non-alcoholic fatty liver disease development. Endocrine 2012, doi:10.1007/s12020-012-9761-5.
-
(2012)
Endocrine
-
-
Li, Y.1
Hai, J.2
Li, L.3
Chen, X.4
Peng, H.5
Cao, M.6
Zhang, Q.7
-
72
-
-
44649155632
-
Ghrelin improves burn-induced multiple organ injury by depressing neutrophil infiltration and the release of pro-inflammatory cytokines
-
Sehirli, O.; Sener, E.; Sener, G.; Cetinel, S.; Erzik, C.; Yegen, B.C. Ghrelin improves burn-induced multiple organ injury by depressing neutrophil infiltration and the release of pro-inflammatory cytokines. Peptides 2008, 29, 1231-1240.
-
(2008)
Peptides
, vol.29
, pp. 1231-1240
-
-
Sehirli, O.1
Sener, E.2
Sener, G.3
Cetinel, S.4
Erzik, C.5
Yegen, B.C.6
-
73
-
-
84859034518
-
Ghrelin attenuates brain injury after traumatic brain injury and uncontrolled hemorrhagic shock in rats
-
Qi, L.; Cui, X.; Dong, W.; Barrera, R.; Nicastro, J.; Coppa, G.F.; Wang, P.; Wu, R. Ghrelin attenuates brain injury after traumatic brain injury and uncontrolled hemorrhagic shock in rats. Mol. Med. 2012, 18, 186-193.
-
(2012)
Mol. Med
, vol.18
, pp. 186-193
-
-
Qi, L.1
Cui, X.2
Dong, W.3
Barrera, R.4
Nicastro, J.5
Coppa, G.F.6
Wang, P.7
Wu, R.8
-
74
-
-
77953929950
-
The anti-inflammatory and neuroprotective effects of ghrelin in subarachnoid hemorrhage-induced oxidative brain damage in rats
-
Ersahin, M.; Toklu, H.Z.; Erzik, C.; Cetinel, S.; Akakin, D.; Velioglu-Ogunc, A.; Tetik, S.; Ozdemir, Z.N.; Sener, G.; Yegen, B.C. The anti-inflammatory and neuroprotective effects of ghrelin in subarachnoid hemorrhage-induced oxidative brain damage in rats. J. Neurotrauma 2010, 27, 1143-1155.
-
(2010)
J. Neurotrauma
, vol.27
, pp. 1143-1155
-
-
Ersahin, M.1
Toklu, H.Z.2
Erzik, C.3
Cetinel, S.4
Akakin, D.5
Velioglu-Ogunc, A.6
Tetik, S.7
Ozdemir, Z.N.8
Sener, G.9
Yegen, B.C.10
-
75
-
-
84859061180
-
Vagal stimulation modulates inflammation through a ghrelin mediated mechanism in traumatic brain injury
-
Bansal, V.; Ryu, S.Y.; Lopez, N.; Allexan, S.; Krzyzaniak, M.; Eliceiri, B.; Baird, A.; Coimbra, R. Vagal stimulation modulates inflammation through a ghrelin mediated mechanism in traumatic brain injury. Inflammation 2012, 35, 214-220.
-
(2012)
Inflammation
, vol.35
, pp. 214-220
-
-
Bansal, V.1
Ryu, S.Y.2
Lopez, N.3
Allexan, S.4
Krzyzaniak, M.5
Eliceiri, B.6
Baird, A.7
Coimbra, R.8
-
76
-
-
0038699022
-
The endocrine response to ghrelin as a function of gender in humans in young and elderly subjects
-
Broglio, F.; Benso, A.; Castiglioni, C.; Gottero, C.; Prodam, F.; Destefanis, S.; Gauna, C.; van der Lely, A.J.; Deghenghi, R.; Bo, M.; et al. The endocrine response to ghrelin as a function of gender in humans in young and elderly subjects. J. Clin. Endocrinol. Metab. 2003, 88, 1537-1542.
-
(2003)
J. Clin. Endocrinol. Metab
, vol.88
, pp. 1537-1542
-
-
Broglio, F.1
Benso, A.2
Castiglioni, C.3
Gottero, C.4
Prodam, F.5
Destefanis, S.6
Gauna, C.7
van der Lely, A.J.8
Deghenghi, R.9
Bo, M.10
-
77
-
-
0028033954
-
Neuroendocrine responses to a novel growth hormone secretagogue, L-692,429, in healthy older subjects
-
Aloi, J.A.; Gertz, B.J.; Hartman, M.L.; Huhn, W.C.; Pezzoli, S.S.; Wittreich, J.M.; Krupa, D.A.; Thorner, M.O. Neuroendocrine responses to a novel growth hormone secretagogue, L-692,429, in healthy older subjects. J. Clin. Endocrinol. Metab. 1994, 79, 943-949.
-
(1994)
J. Clin. Endocrinol. Metab
, vol.79
, pp. 943-949
-
-
Aloi, J.A.1
Gertz, B.J.2
Hartman, M.L.3
Huhn, W.C.4
Pezzoli, S.S.5
Wittreich, J.M.6
Krupa, D.A.7
Thorner, M.O.8
-
78
-
-
33645514977
-
Effect of aging on the response of ghrelin to acute weight loss
-
Yukawa, M.; Cummings, D.E.; Matthys, C.C.; Callahan, H.S.; Frayo, R.S.; Spiekerman, C.F.; Weigle, D.S. Effect of aging on the response of ghrelin to acute weight loss. J. Am. Geriatr. Soc. 2006, 54, 648-653.
-
(2006)
J. Am. Geriatr. Soc
, vol.54
, pp. 648-653
-
-
Yukawa, M.1
Cummings, D.E.2
Matthys, C.C.3
Callahan, H.S.4
Frayo, R.S.5
Spiekerman, C.F.6
Weigle, D.S.7
-
79
-
-
77957274035
-
Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons
-
Briggs, D.I.; Enriori, P.J.; Lemus, M.B.; Cowley, M.A.; Andrews, Z.B. Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons. Endocrinology 2010, 151, 4745-4755.
-
(2010)
Endocrinology
, vol.151
, pp. 4745-4755
-
-
Briggs, D.I.1
Enriori, P.J.2
Lemus, M.B.3
Cowley, M.A.4
Andrews, Z.B.5
-
80
-
-
0035082265
-
Circulating ghrelin levels are decreased in human obesity
-
Tschop, M.; Weyer, C.; Tataranni, P.A.; Devanarayan, V.; Ravussin, E.; Heiman, M.L. Circulating ghrelin levels are decreased in human obesity. Diabetes 2001, 50, 707-709.
-
(2001)
Diabetes
, vol.50
, pp. 707-709
-
-
Tschop, M.1
Weyer, C.2
Tataranni, P.A.3
Devanarayan, V.4
Ravussin, E.5
Heiman, M.L.6
-
81
-
-
0141643291
-
Low plasma ghrelin is associated with insulin resistance, hypertension, and the prevalence of type 2 diabetes
-
Poykko, S.M.; Kellokoski, E.; Horkko, S.; Kauma, H.; Kesaniemi, Y.A.; Ukkola, O. Low plasma ghrelin is associated with insulin resistance, hypertension, and the prevalence of type 2 diabetes. Diabetes 2003, 52, 2546-2553.
-
(2003)
Diabetes
, vol.52
, pp. 2546-2553
-
-
Poykko, S.M.1
Kellokoski, E.2
Horkko, S.3
Kauma, H.4
Kesaniemi, Y.A.5
Ukkola, O.6
-
82
-
-
0037955956
-
Ghrelin Arg51Gln mutation is a risk factor for Type 2 diabetes and hypertension in a random sample of middle-aged subjects
-
Poykko, S.; Ukkola, O.; Kauma, H.; Savolainen, M.J.; Kesaniemi, Y.A. Ghrelin Arg51Gln mutation is a risk factor for Type 2 diabetes and hypertension in a random sample of middle-aged subjects. Diabetologia 2003, 46, 455-458.
-
(2003)
Diabetologia
, vol.46
, pp. 455-458
-
-
Poykko, S.1
Ukkola, O.2
Kauma, H.3
Savolainen, M.J.4
Kesaniemi, Y.A.5
-
83
-
-
4644249772
-
Regulation of growth hormone secretagogue receptor gene expression in the arcuate nuclei of the rat by leptin and ghrelin
-
Nogueiras, R.; Tovar, S.; Mitchell, S.E.; Rayner, D.V.; Archer, Z.A.; Dieguez, C.; Williams, L.M. Regulation of growth hormone secretagogue receptor gene expression in the arcuate nuclei of the rat by leptin and ghrelin. Diabetes 2004, 53, 2552-2558.
-
(2004)
Diabetes
, vol.53
, pp. 2552-2558
-
-
Nogueiras, R.1
Tovar, S.2
Mitchell, S.E.3
Rayner, D.V.4
Archer, Z.A.5
Dieguez, C.6
Williams, L.M.7
-
84
-
-
33750625913
-
Translational research on the clinical applications of ghrelin
-
Akamizu, T.; Kangawa, K. Translational research on the clinical applications of ghrelin. Endocrine J. 2006, 53, 585-591.
-
(2006)
Endocrine J
, vol.53
, pp. 585-591
-
-
Akamizu, T.1
Kangawa, K.2
-
85
-
-
34447545671
-
Constant intravenous ghrelin infusion in healthy young men: Clinical pharmacokinetics and metabolic effects
-
Vestergaard, E.T.; Hansen, T.K.; Gormsen, L.C.; Jakobsen, P.; Moller, N.; Christiansen, J.S.; Jorgensen, J.O. Constant intravenous ghrelin infusion in healthy young men: Clinical pharmacokinetics and metabolic effects. Am. J. Physiol. Endocrinol. Metab. 2007, 292, E1829-E1836.
-
(2007)
Am. J. Physiol. Endocrinol. Metab
, vol.292
-
-
Vestergaard, E.T.1
Hansen, T.K.2
Gormsen, L.C.3
Jakobsen, P.4
Moller, N.5
Christiansen, J.S.6
Jorgensen, J.O.7
-
86
-
-
0032845121
-
Ischemic cell death in brain neurons
-
Lipton, P. Ischemic cell death in brain neurons. Physiol. Rev. 1999, 79, 1431-1568.
-
(1999)
Physiol. Rev
, vol.79
, pp. 1431-1568
-
-
Lipton, P.1
-
87
-
-
78649951449
-
Glutamatergic regulation of ghrelin-induced activation of the mesolimbic dopamine system
-
Jerlhag, E.; Egecioglu, E.; Dickson, S.L.; Engel, J.A. Glutamatergic regulation of ghrelin-induced activation of the mesolimbic dopamine system. Addict. Biol. 2011, 16, 82-91.
-
(2011)
Addict. Biol
, vol.16
, pp. 82-91
-
-
Jerlhag, E.1
Egecioglu, E.2
Dickson, S.L.3
Engel, J.A.4
-
88
-
-
0034065936
-
Glutamate as a neurotransmitter in the brain: Review of physiology and pathology
-
Meldrum, B.S. Glutamate as a neurotransmitter in the brain: Review of physiology and pathology. J. Nutr. 2000, 130, 1007S-1015S.
-
(2000)
J. Nutr
, vol.130
-
-
Meldrum, B.S.1
-
89
-
-
80054978194
-
Body weight after stroke: Lessons from the obesity paradox
-
Scherbakov, N.; Dirnagl, U.; Doehner, W. Body weight after stroke: Lessons from the obesity paradox. Stroke 2011, 42, 3646-3650.
-
(2011)
Stroke
, vol.42
, pp. 3646-3650
-
-
Scherbakov, N.1
Dirnagl, U.2
Doehner, W.3
|