메뉴 건너뛰기




Volumn 89, Issue 1, 2015, Pages 181-194

Insight into the mechanism of inhibition of adeno-associated virus by the Mre11/Rad50/Nbs1 complex

Author keywords

[No Author keywords available]

Indexed keywords

MRE11 PROTEIN; NIBRIN; RAD50 PROTEIN; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; DNA LIGASE; E1B55K PROTEIN, ADENOVIRUS; E4ORF6 PROTEIN, ADENOVIRUS; MRE11A PROTEIN, HUMAN; NBN PROTEIN, HUMAN; NUCLEAR PROTEIN; RAD50 PROTEIN, HUMAN; VIRUS PROTEIN;

EID: 84919448546     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01990-14     Document Type: Article
Times cited : (40)

References (83)
  • 1
    • 0018856473 scopus 로고
    • Nucleotide sequence of the inverted terminal repetition in adeno-associated virus DNA
    • Lusby E, Fife KH, Berns KI. 1980. Nucleotide sequence of the inverted terminal repetition in adeno-associated virus DNA. J Virol 34:402-409.
    • (1980) J Virol , vol.34 , pp. 402-409
    • Lusby, E.1    Fife, K.H.2    Berns, K.I.3
  • 2
    • 0017167291 scopus 로고
    • Rolling hairpin model for replication of parvovirus and linear chromosomal DNA
    • Tattersall P, Ward DC. 1976. Rolling hairpin model for replication of parvovirus and linear chromosomal DNA. Nature 263:106-109. http://dx.doi.org/10.1038/263106a0.
    • (1976) Nature , vol.263 , pp. 106-109
    • Tattersall, P.1    Ward, D.C.2
  • 3
    • 0024311525 scopus 로고
    • Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression
    • Samulski RJ, Chang LS, Shenk T. 1989. Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression. J Virol 63:3822-3828.
    • (1989) J Virol , vol.63 , pp. 3822-3828
    • Samulski, R.J.1    Chang, L.S.2    Shenk, T.3
  • 4
    • 0020684648 scopus 로고
    • Nucleotide sequence and organization of the adeno-associated virus 2 genome
    • Srivastava A, Lusby EW, Berns KI. 1983. Nucleotide sequence and organization of the adeno-associated virus 2 genome. J Virol 45:555-564.
    • (1983) J Virol , vol.45 , pp. 555-564
    • Srivastava, A.1    Lusby, E.W.2    Berns, K.I.3
  • 5
    • 38349096769 scopus 로고    scopus 로고
    • Complete in vitro reconstitution of adeno-associated virus DNA replication requires the minichromosome maintenance complex proteins
    • Nash K, Chen W, Muzyczka N. 2008. Complete in vitro reconstitution of adeno-associated virus DNA replication requires the minichromosome maintenance complex proteins. J Virol 82:1458-1464. http://dx.doi.org/10.1128/JVI.01968-07.
    • (2008) J Virol , vol.82 , pp. 1458-1464
    • Nash, K.1    Chen, W.2    Muzyczka, N.3
  • 6
    • 21244466776 scopus 로고    scopus 로고
    • Helper functions required for wild type and recombinant adeno-associated virus growth
    • Geoffroy MC, Salvetti A. 2005. Helper functions required for wild type and recombinant adeno-associated virus growth. Curr Gene Ther 5:265-271. http://dx.doi.org/10.2174/1566523054064977.
    • (2005) Curr Gene Ther , vol.5 , pp. 265-271
    • Geoffroy, M.C.1    Salvetti, A.2
  • 7
    • 77957951602 scopus 로고    scopus 로고
    • Genomes in conflict: maintaining genome integrity during virus infection
    • Weitzman MD, Lilley CE, Chaurushiya MS. 2010. Genomes in conflict: maintaining genome integrity during virus infection. Annu Rev Microbiol 64:61-81. http://dx.doi.org/10.1146/annurev.micro.112408.134016.
    • (2010) Annu Rev Microbiol , vol.64 , pp. 61-81
    • Weitzman, M.D.1    Lilley, C.E.2    Chaurushiya, M.S.3
  • 8
    • 84866324649 scopus 로고    scopus 로고
    • DNA viruses and the cellular DNA-damage response
    • Turnell AS, Grand RJ. 2012. DNA viruses and the cellular DNA-damage response. J Gen Virol 93:2076-2097. http://dx.doi.org/10.1099/vir.0.044412-0.
    • (2012) J Gen Virol , vol.93 , pp. 2076-2097
    • Turnell, A.S.1    Grand, R.J.2
  • 9
    • 47749127769 scopus 로고    scopus 로고
    • Recombinant adeno-associated viral vectors are deficient in provoking a DNA damage response
    • Fragkos M, Breuleux M, Clement N, Beard P. 2008. Recombinant adeno-associated viral vectors are deficient in provoking a DNA damage response. J Virol 82:7379-7387. http://dx.doi.org/10.1128/JVI.00358-08.
    • (2008) J Virol , vol.82 , pp. 7379-7387
    • Fragkos, M.1    Breuleux, M.2    Clement, N.3    Beard, P.4
  • 10
    • 66149143110 scopus 로고    scopus 로고
    • Adenoassociated virus replication induces a DNA damage response coordinated by DNA-dependent protein kinase
    • Schwartz RA, Carson CT, Schuberth C, Weitzman MD. 2009. Adenoassociated virus replication induces a DNA damage response coordinated by DNA-dependent protein kinase. J Virol 83:6269-6278. http://dx.doi.org/10.1128/JVI.00318-09.
    • (2009) J Virol , vol.83 , pp. 6269-6278
    • Schwartz, R.A.1    Carson, C.T.2    Schuberth, C.3    Weitzman, M.D.4
  • 11
    • 0033567129 scopus 로고    scopus 로고
    • Structural analysis of adeno-associated virus transduction circular intermediates
    • Duan D, Yan Z, Yue Y, Engelhardt JF. 1999. Structural analysis of adeno-associated virus transduction circular intermediates. Virology 261: 8-14. http://dx.doi.org/10.1006/viro.1999.9821.
    • (1999) Virology , vol.261 , pp. 8-14
    • Duan, D.1    Yan, Z.2    Yue, Y.3    Engelhardt, J.F.4
  • 12
    • 10944269753 scopus 로고    scopus 로고
    • Integration of adenoassociated virus (AAV) and recombinant AAV vectors
    • McCarty DM, Young SM, Jr, Samulski RJ. 2004. Integration of adenoassociated virus (AAV) and recombinant AAV vectors. Annu Rev Genet 38:819-845. http://dx.doi.org/10.1146/annurev.genet.37.110801.143717.
    • (2004) Annu Rev Genet , vol.38 , pp. 819-845
    • McCarty, D.M.1    Young Jr., S.M.2    Samulski, R.J.3
  • 13
    • 69249217762 scopus 로고    scopus 로고
    • Adeno-associated virus and adenovirus coinfection induces a cellular DNA damage and repair response via redundant phosphatidylinositol 3-like kinase pathways
    • Collaco RF, Bevington JM, Bhrigu V, Kalman-Maltese V, Trempe JP. 2009. Adeno-associated virus and adenovirus coinfection induces a cellular DNA damage and repair response via redundant phosphatidylinositol 3-like kinase pathways. Virology 392:24-33. http://dx.doi.org/10.1016/j.virol.2009.06.005.
    • (2009) Virology , vol.392 , pp. 24-33
    • Collaco, R.F.1    Bevington, J.M.2    Bhrigu, V.3    Kalman-Maltese, V.4    Trempe, J.P.5
  • 14
    • 78650859568 scopus 로고    scopus 로고
    • The effect of DNA-dependent protein kinase on adeno-associated virus replication
    • Choi YK, Nash K, Byrne BJ, Muzyczka N, Song S. 2010. The effect of DNA-dependent protein kinase on adeno-associated virus replication. PLoS One 5:e15073. http://dx.doi.org/10.1371/journal.pone.0015073.
    • (2010) PLoS One , vol.5
    • Choi, Y.K.1    Nash, K.2    Byrne, B.J.3    Muzyczka, N.4    Song, S.5
  • 15
    • 35148863458 scopus 로고    scopus 로고
    • The role of DNA-PKcs and Artemis in opening viral DNA hairpin termini in various tissues in mice
    • Inagaki K, Ma C, Storm TA, Kay MA, Nakai H. 2007. The role of DNA-PKcs and Artemis in opening viral DNA hairpin termini in various tissues in mice. J Virol 81:11304-11321. http://dx.doi.org/10.1128/JVI.01225-07.
    • (2007) J Virol , vol.81 , pp. 11304-11321
    • Inagaki, K.1    Ma, C.2    Storm, T.A.3    Kay, M.A.4    Nakai, H.5
  • 16
    • 36348963101 scopus 로고    scopus 로고
    • The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication
    • Schwartz RA, Palacios JA, Cassell GD, Adam S, Giacca M, Weitzman MD. 2007. The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication. J Virol 81:12936-12945. http://dx.doi.org/10.1128/JVI.01523-07.
    • (2007) J Virol , vol.81 , pp. 12936-12945
    • Schwartz, R.A.1    Palacios, J.A.2    Cassell, G.D.3    Adam, S.4    Giacca, M.5    Weitzman, M.D.6
  • 17
    • 84896064537 scopus 로고    scopus 로고
    • What's the damage? The impact of pathogens on pathways that maintain host genome integrity
    • Weitzman MD, Weitzman JB. 2014. What's the damage?. The impact of pathogens on pathways that maintain host genome integrity. Cell Host Microbe 15:283-294. http://dx.doi.org/10.1016/j.chom.2014.02.010.
    • (2014) Cell Host Microbe , vol.15 , pp. 283-294
    • Weitzman, M.D.1    Weitzman, J.B.2
  • 18
    • 6944226229 scopus 로고    scopus 로고
    • MRE11/RAD50/NBS1: complex activities
    • Assenmacher N, Hopfner KP. 2004. MRE11/RAD50/NBS1: complex activities. Chromosoma 113:157-166. http://dx.doi.org/10.1007/s00412-004-0306-4.
    • (2004) Chromosoma , vol.113 , pp. 157-166
    • Assenmacher, N.1    Hopfner, K.P.2
  • 19
    • 77955841725 scopus 로고    scopus 로고
    • The MRN complex in double-strand break repair and telomere maintenance
    • Lamarche BJ, Orazio NI, Weitzman MD. 2010. The MRN complex in double-strand break repair and telomere maintenance. FEBS Lett 584: 3682-3695. http://dx.doi.org/10.1016/j.febslet.2010.07.029.
    • (2010) FEBS Lett , vol.584 , pp. 3682-3695
    • Lamarche, B.J.1    Orazio, N.I.2    Weitzman, M.D.3
  • 20
    • 68249138694 scopus 로고    scopus 로고
    • Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells
    • Rass E, Grabarz A, Plo I, Gautier J, Bertrand P, Lopez BS. 2009. Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells. Nat Struct Mol Biol 16:819-824. http://dx.doi.org/10.1038/nsmb.1641.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 819-824
    • Rass, E.1    Grabarz, A.2    Plo, I.3    Gautier, J.4    Bertrand, P.5    Lopez, B.S.6
  • 21
    • 78951474460 scopus 로고    scopus 로고
    • The MRE11 complex: starting from the ends
    • Stracker TH, Petrini JH. 2011. The MRE11 complex: starting from the ends. Nat Rev Mol Cell Biol 12:90-103. http://dx.doi.org/10.1038/nrm3047.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 90-103
    • Stracker, T.H.1    Petrini, J.H.2
  • 22
    • 0037341599 scopus 로고    scopus 로고
    • Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNAdamage
    • Lukas C, Falck J, Bartkova J, Bartek J, Lukas J. 2003. Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNAdamage. Nat Cell Biol 5:255-260. http://dx.doi.org/10.1038/ncb945.
    • (2003) Nat Cell Biol , vol.5 , pp. 255-260
    • Lukas, C.1    Falck, J.2    Bartkova, J.3    Bartek, J.4    Lukas, J.5
  • 23
    • 0032562595 scopus 로고    scopus 로고
    • In situ visualization of DNA double-strand break repair in human fibroblasts
    • Nelms BE, Maser RS, MacKay JF, Lagally MG, Petrini JH. 1998. In situ visualization of DNA double-strand break repair in human fibroblasts. Science 280:590-592. http://dx.doi.org/10.1126/science.280.5363.590.
    • (1998) Science , vol.280 , pp. 590-592
    • Nelms, B.E.1    Maser, R.S.2    MacKay, J.F.3    Lagally, M.G.4    Petrini, J.H.5
  • 24
    • 0142136826 scopus 로고    scopus 로고
    • Requirement of the MRN complex for ATM activation by DNA damage
    • Uziel T, Lerenthal Y, Moyal L, Andegeko Y, Mittelman L, Shiloh Y. 2003. Requirement of the MRN complex for ATM activation by DNA damage. EMBO J 22:5612-5621. http://dx.doi.org/10.1093/emboj/cdg541.
    • (2003) EMBO J , vol.22 , pp. 5612-5621
    • Uziel, T.1    Lerenthal, Y.2    Moyal, L.3    Andegeko, Y.4    Mittelman, L.5    Shiloh, Y.6
  • 25
    • 34547950170 scopus 로고    scopus 로고
    • The Mre11-Rad50-Nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and Rad3-related protein (ATR) to regulate the S-phase checkpoint following UV treatment
    • Olson E, Nievera CJ, Lee AY, Chen L, Wu X. 2007. The Mre11-Rad50-Nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and Rad3-related protein (ATR) to regulate the S-phase checkpoint following UV treatment. J Biol Chem 282:22939-22952. http://dx.doi.org/10.1074/jbc.M702162200.
    • (2007) J Biol Chem , vol.282 , pp. 22939-22952
    • Olson, E.1    Nievera, C.J.2    Lee, A.Y.3    Chen, L.4    Wu, X.5
  • 26
    • 0345732687 scopus 로고    scopus 로고
    • The Mre11 complex is required for ATM activation and the G2/M checkpoint
    • Carson CT, Schwartz RA, Stracker TH, Lilley CE, Lee DV, Weitzman MD. 2003. The Mre11 complex is required for ATM activation and the G2/M checkpoint. EMBO J 22:6610-6620. http://dx.doi.org/10.1093/emboj/cdg630.
    • (2003) EMBO J , vol.22 , pp. 6610-6620
    • Carson, C.T.1    Schwartz, R.A.2    Stracker, T.H.3    Lilley, C.E.4    Lee, D.V.5    Weitzman, M.D.6
  • 27
    • 40549138765 scopus 로고    scopus 로고
    • Processing of recombinant AAV genomes occurs in specific nuclear structures that overlap with foci of DNA-damage-response proteins
    • Cervelli T, Palacios JA, Zentilin L, Mano M, Schwartz RA, Weitzman MD, Giacca M. 2008. Processing of recombinant AAV genomes occurs in specific nuclear structures that overlap with foci of DNA-damage-response proteins. J Cell Sci 121:349-357. http://dx.doi.org/10.1242/jcs.003632.
    • (2008) J Cell Sci , vol.121 , pp. 349-357
    • Cervelli, T.1    Palacios, J.A.2    Zentilin, L.3    Mano, M.4    Schwartz, R.A.5    Weitzman, M.D.6    Giacca, M.7
  • 28
    • 84869083816 scopus 로고    scopus 로고
    • Terminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins
    • Lovric J, Mano M, Zentilin L, Eulalio A, Zacchigna S, Giacca M. 2012. Terminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins. Mol Ther 20:2087-2097. http://dx.doi.org/10.1038/mt.2012.144.
    • (2012) Mol Ther , vol.20 , pp. 2087-2097
    • Lovric, J.1    Mano, M.2    Zentilin, L.3    Eulalio, A.4    Zacchigna, S.5    Giacca, M.6
  • 29
  • 30
    • 24044489232 scopus 로고    scopus 로고
    • Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection
    • Shirata N, Kudoh A, Daikoku T, Tatsumi Y, Fujita M, Kiyono T, Sugaya Y, Isomura H, Ishizaki K, Tsurumi T. 2005. Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection. J Biol Chem 280:30336-30341. http://dx.doi.org/10.1074/jbc.M500976200.
    • (2005) J Biol Chem , vol.280 , pp. 30336-30341
    • Shirata, N.1    Kudoh, A.2    Daikoku, T.3    Tatsumi, Y.4    Fujita, M.5    Kiyono, T.6    Sugaya, Y.7    Isomura, H.8    Ishizaki, K.9    Tsurumi, T.10
  • 31
    • 4644296028 scopus 로고    scopus 로고
    • Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage response
    • Wilkinson DE, Weller SK. 2004. Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage response. J Virol 78:4783-4796. http://dx.doi.org/10.1128/JVI.78.9.4783-4796.2004.
    • (2004) J Virol , vol.78 , pp. 4783-4796
    • Wilkinson, D.E.1    Weller, S.K.2
  • 32
    • 0037130170 scopus 로고    scopus 로고
    • Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex
    • Stracker TH, Carson CT, Weitzman MD. 2002. Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex. Nature 418:348-352. http://dx.doi.org/10.1038/nature00863.
    • (2002) Nature , vol.418 , pp. 348-352
    • Stracker, T.H.1    Carson, C.T.2    Weitzman, M.D.3
  • 33
    • 18744362169 scopus 로고    scopus 로고
    • Serotype-specific reorganization of the Mre11 complex by adenoviral E4orf3 proteins
    • Stracker TH, Lee DV, Carson CT, Araujo FD, Ornelles DA, Weitzman MD. 2005. Serotype-specific reorganization of the Mre11 complex by adenoviral E4orf3 proteins. J Virol 79:6664-6673. http://dx.doi.org/10.1128/JVI.79.11.6664-6673.2005.
    • (2005) J Virol , vol.79 , pp. 6664-6673
    • Stracker, T.H.1    Lee, D.V.2    Carson, C.T.3    Araujo, F.D.4    Ornelles, D.A.5    Weitzman, M.D.6
  • 34
    • 18144401244 scopus 로고    scopus 로고
    • Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication
    • Evans JD, Hearing P. 2005. Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication. J Virol 79:6207-6215. http://dx.doi.org/10.1128/JVI.79.10.6207-6215.2005.
    • (2005) J Virol , vol.79 , pp. 6207-6215
    • Evans, J.D.1    Hearing, P.2
  • 35
    • 0029923638 scopus 로고    scopus 로고
    • Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors
    • Ferrari FK, Samulski T, Shenk T, Samulski RJ. 1996. Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors. J Virol 70:3227-3234.
    • (1996) J Virol , vol.70 , pp. 3227-3234
    • Ferrari, F.K.1    Samulski, T.2    Shenk, T.3    Samulski, R.J.4
  • 36
    • 0029655894 scopus 로고    scopus 로고
    • Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis
    • Fisher KJ, Gao GP, Weitzman MD, DeMatteo R, Burda JF, Wilson JM. 1996. Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis. J Virol 70:520-532.
    • (1996) J Virol , vol.70 , pp. 520-532
    • Fisher, K.J.1    Gao, G.P.2    Weitzman, M.D.3    DeMatteo, R.4    Burda, J.F.5    Wilson, J.M.6
  • 37
    • 0036140216 scopus 로고    scopus 로고
    • Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity
    • Rabinowitz JE, Rolling F, Li C, Conrath H, Xiao W, Xiao X, Samulski RJ. 2002. Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity. J Virol 76:791-801. http://dx.doi.org/10.1128/JVI.76.2.791-801.2002.
    • (2002) J Virol , vol.76 , pp. 791-801
    • Rabinowitz, J.E.1    Rolling, F.2    Li, C.3    Conrath, H.4    Xiao, W.5    Xiao, X.6    Samulski, R.J.7
  • 38
    • 2642642141 scopus 로고    scopus 로고
    • Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus
    • Xiao X, Li J, Samulski RJ. 1998. Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus. J Virol 72:2224-2232.
    • (1998) J Virol , vol.72 , pp. 2224-2232
    • Xiao, X.1    Li, J.2    Samulski, R.J.3
  • 39
    • 0032415073 scopus 로고    scopus 로고
    • Inducible long-term gene expression in brain with adeno-associated virus gene transfer
    • Haberman RP, McCown TJ, Samulski RJ. 1998. Inducible long-term gene expression in brain with adeno-associated virus gene transfer. Gene Ther 5:1604-1611. http://dx.doi.org/10.1038/sj.gt.3300782.
    • (1998) Gene Ther , vol.5 , pp. 1604-1611
    • Haberman, R.P.1    McCown, T.J.2    Samulski, R.J.3
  • 40
    • 58149458863 scopus 로고    scopus 로고
    • A small regulatory element from chromosome 19 enhances liver-specific gene expression
    • Li C, Hirsch M, Carter P, Asokan A, Zhou X, Wu Z, Samulski RJ. 2009. A small regulatory element from chromosome 19 enhances liver-specific gene expression. Gene Ther 16:43-51. http://dx.doi.org/10.1038/gt.2008.134.
    • (2009) Gene Ther , vol.16 , pp. 43-51
    • Li, C.1    Hirsch, M.2    Carter, P.3    Asokan, A.4    Zhou, X.5    Wu, Z.6    Samulski, R.J.7
  • 41
    • 0029995531 scopus 로고    scopus 로고
    • A "humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cells
    • Zolotukhin S, Potter M, Hauswirth WW, Guy J, Muzyczka N. 1996. A "humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cells. J Virol 70:4646-4654.
    • (1996) J Virol , vol.70 , pp. 4646-4654
    • Zolotukhin, S.1    Potter, M.2    Hauswirth, W.W.3    Guy, J.4    Muzyczka, N.5
  • 42
    • 1842416600 scopus 로고    scopus 로고
    • Structural analysis of the adenovirus type 5 E1B 55-kilodalton-E4orf6 protein complex
    • Rubenwolf S, Schutt H, Nevels M, Wolf H, Dobner T. 1997. Structural analysis of the adenovirus type 5 E1B 55-kilodalton-E4orf6 protein complex. J Virol 71:1115-1123.
    • (1997) J Virol , vol.71 , pp. 1115-1123
    • Rubenwolf, S.1    Schutt, H.2    Nevels, M.3    Wolf, H.4    Dobner, T.5
  • 43
    • 77749321137 scopus 로고    scopus 로고
    • Creating a novel origin of replication through modulating DNA-protein interfaces
    • Hewitt FC, Samulski RJ. 2010. Creating a novel origin of replication through modulating DNA-protein interfaces. PLoS One 5:e8850. http://dx.doi.org/10.1371/journal.pone.0008850.
    • (2010) PLoS One , vol.5
    • Hewitt, F.C.1    Samulski, R.J.2
  • 44
    • 0031104792 scopus 로고    scopus 로고
    • Gene transfer by adenoassociated virus vectors into the central nervous system
    • Xiao X, Li J, McCown TJ, Samulski RJ. 1997. Gene transfer by adenoassociated virus vectors into the central nervous system. Exp Neurol 144: 113-124. http://dx.doi.org/10.1006/exnr.1996.6396.
    • (1997) Exp Neurol , vol.144 , pp. 113-124
    • Xiao, X.1    Li, J.2    McCown, T.J.3    Samulski, R.J.4
  • 45
    • 1642271492 scopus 로고    scopus 로고
    • A parvovirus isolated from royal python (Python regius) is a member of the genus Dependovirus
    • Farkas SL, Zadori Z, Benko M, Essbauer S, Harrach B, Tijssen P. 2004. A parvovirus isolated from royal python (Python regius) is a member of the genus Dependovirus. J Gen Virol 85:555-561. http://dx.doi.org/10.1099/vir.0.19616-0.
    • (2004) J Gen Virol , vol.85 , pp. 555-561
    • Farkas, S.L.1    Zadori, Z.2    Benko, M.3    Essbauer, S.4    Harrach, B.5    Tijssen, P.6
  • 46
    • 34347252689 scopus 로고    scopus 로고
    • Production and characterization of adeno-associated viral vectors
    • Grieger JC, Choi VW, Samulski RJ. 2006. Production and characterization of adeno-associated viral vectors. Nat Protoc 1:1412-1428. http://dx.doi.org/10.1038/nprot.2006.207.
    • (2006) Nat Protoc , vol.1 , pp. 1412-1428
    • Grieger, J.C.1    Choi, V.W.2    Samulski, R.J.3
  • 47
    • 33750357800 scopus 로고    scopus 로고
    • Host cell DNA repair pathways in adeno-associated viral genome processing
    • Choi VW, McCarty DM, Samulski RJ. 2006. Host cell DNA repair pathways in adeno-associated viral genome processing. J Virol 80:10346-10356. http://dx.doi.org/10.1128/JVI.00841-06.
    • (2006) J Virol , vol.80 , pp. 10346-10356
    • Choi, V.W.1    McCarty, D.M.2    Samulski, R.J.3
  • 49
    • 0035979213 scopus 로고    scopus 로고
    • ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation
    • Nghiem P, Park PK, Kim Y, Vaziri C, Schreiber SL. 2001. ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation. Proc Natl Acad Sci USA 98:9092-9097. http://dx.doi.org/10.1073/pnas.161281798.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9092-9097
    • Nghiem, P.1    Park, P.K.2    Kim, Y.3    Vaziri, C.4    Schreiber, S.L.5
  • 50
    • 0346156075 scopus 로고    scopus 로고
    • Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice
    • Theunissen JW, Kaplan MI, Hunt PA, Williams BR, Ferguson DO, Alt FW, Petrini JH. 2003. Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice. Mol Cell 12: 1511-1523. http://dx.doi.org/10.1016/S1097-2765(03)00455-6.
    • (2003) Mol Cell , vol.12 , pp. 1511-1523
    • Theunissen, J.W.1    Kaplan, M.I.2    Hunt, P.A.3    Williams, B.R.4    Ferguson, D.O.5    Alt, F.W.6    Petrini, J.H.7
  • 52
    • 52949109260 scopus 로고    scopus 로고
    • Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation
    • Buis J, Wu Y, Deng Y, Leddon J, Westfield G, Eckersdorff M, Sekiguchi JM, Chang S, Ferguson DO. 2008. Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation. Cell 135:85-96. http://dx.doi.org/10.1016/j.cell.2008.08.015.
    • (2008) Cell , vol.135 , pp. 85-96
    • Buis, J.1    Wu, Y.2    Deng, Y.3    Leddon, J.4    Westfield, G.5    Eckersdorff, M.6    Sekiguchi, J.M.7    Chang, S.8    Ferguson, D.O.9
  • 53
    • 84869015419 scopus 로고    scopus 로고
    • Cytoplasmic trafficking, endosomal escape, and perinuclear accumulation of adeno-associated virus type 2 particles are facilitated by microtubule network
    • Xiao PJ, Samulski RJ. 2012. Cytoplasmic trafficking, endosomal escape, and perinuclear accumulation of adeno-associated virus type 2 particles are facilitated by microtubule network. J Virol 86:10462-10473. http://dx.doi.org/10.1128/JVI.00935-12.
    • (2012) J Virol , vol.86 , pp. 10462-10473
    • Xiao, P.J.1    Samulski, R.J.2
  • 55
    • 0034882826 scopus 로고    scopus 로고
    • Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis
    • McCarty DM, Monahan PE, Samulski RJ. 2001. Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis. Gene Ther 8:1248-1254. http://dx.doi.org/10.1038/sj.gt.3301514.
    • (2001) Gene Ther , vol.8 , pp. 1248-1254
    • McCarty, D.M.1    Monahan, P.E.2    Samulski, R.J.3
  • 56
    • 84859440283 scopus 로고    scopus 로고
    • The AAV vector toolkit: poised at the clinical crossroads
    • Asokan A, Schaffer DV, Samulski RJ. 2012. The AAV vector toolkit: poised at the clinical crossroads. Mol Ther 20:699-708. http://dx.doi.org/10.1038/mt.2011.287.
    • (2012) Mol Ther , vol.20 , pp. 699-708
    • Asokan, A.1    Schaffer, D.V.2    Samulski, R.J.3
  • 57
    • 0036276388 scopus 로고    scopus 로고
    • The Mre11 complex: at the crossroads of DNA repair and checkpoint signalling
    • D'Amours D, Jackson SP. 2002. The Mre11 complex: at the crossroads of DNA repair and checkpoint signalling. Nat Rev Mol Cell Biol 3:317-327. http://dx.doi.org/10.1038/nrm805.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 317-327
    • D'Amours, D.1    Jackson, S.P.2
  • 58
    • 77956623746 scopus 로고    scopus 로고
    • Differential effects of DNA doublestrand break repair pathways on single-strand and self-complementary adeno-associated virus vector genomes
    • Cataldi MP, McCarty DM. 2010. Differential effects of DNA doublestrand break repair pathways on single-strand and self-complementary adeno-associated virus vector genomes. J Virol 84:8673-8682. http://dx.doi.org/10.1128/JVI.00641-10.
    • (2010) J Virol , vol.84 , pp. 8673-8682
    • Cataldi, M.P.1    McCarty, D.M.2
  • 59
    • 0034008332 scopus 로고    scopus 로고
    • Loss of ATM function enhances recombinant adeno-associated virus transduction and integration through pathways similar to UV irradiation
    • Sanlioglu S, Benson P, Engelhardt JF. 2000. Loss of ATM function enhances recombinant adeno-associated virus transduction and integration through pathways similar to UV irradiation. Virology 268:68-78. http://dx.doi.org/10.1006/viro.1999.0137.
    • (2000) Virology , vol.268 , pp. 68-78
    • Sanlioglu, S.1    Benson, P.2    Engelhardt, J.F.3
  • 60
    • 0027203525 scopus 로고
    • Isolation of two cell lines from a human malignant glioma specimen differing in sensitivity to radiation and chemotherapeutic drugs
    • Allalunis-Turner MJ, Barron GM, Day RS, III, Dobler KD, Mirzayans R. 1993. Isolation of two cell lines from a human malignant glioma specimen differing in sensitivity to radiation and chemotherapeutic drugs. Radiat Res 134:349-354. http://dx.doi.org/10.2307/3578196.
    • (1993) Radiat Res , vol.134 , pp. 349-354
    • Allalunis-Turner, M.J.1    Barron, G.M.2    Day III, R.S.3    Dobler, K.D.4    Mirzayans, R.5
  • 63
    • 0141869885 scopus 로고    scopus 로고
    • Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress
    • Tuo J, Jaruga P, Rodriguez H, Bohr VA, Dizdaroglu M. 2003. Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress. FASEB J 17:668-674. http://dx.doi.org/10.1096/fj.02-0851com.
    • (2003) FASEB J , vol.17 , pp. 668-674
    • Tuo, J.1    Jaruga, P.2    Rodriguez, H.3    Bohr, V.A.4    Dizdaroglu, M.5
  • 65
    • 58149295717 scopus 로고    scopus 로고
    • Protein arginine methylation in mammals: who, what, and why
    • Bedford MT, Clarke SG. 2009. Protein arginine methylation in mammals: who, what, and why. Mol Cell 33:1-13. http://dx.doi.org/10.1016/j.molcel.2008.12.013.
    • (2009) Mol Cell , vol.33 , pp. 1-13
    • Bedford, M.T.1    Clarke, S.G.2
  • 66
    • 64049093048 scopus 로고    scopus 로고
    • Reducing the risk of adeno-associated virus (AAV) vector mobilization with AAV type 5 vectors
    • Hewitt FC, Li C, Gray SJ, Cockrell S, Washburn M, Samulski RJ. 2009. Reducing the risk of adeno-associated virus (AAV) vector mobilization with AAV type 5 vectors. J Virol 83:3919-3929. http://dx.doi.org/10.1128/JVI.02466-08.
    • (2009) J Virol , vol.83 , pp. 3919-3929
    • Hewitt, F.C.1    Li, C.2    Gray, S.J.3    Cockrell, S.4    Washburn, M.5    Samulski, R.J.6
  • 67
    • 84880577366 scopus 로고    scopus 로고
    • The kinase activity of ataxia-telangiectasia mutated interferes with adenovirus E4 mutant DNA replication
    • Gautam D, Bridge E. 2013. The kinase activity of ataxia-telangiectasia mutated interferes with adenovirus E4 mutant DNA replication. J Virol 87:8687-8696. http://dx.doi.org/10.1128/JVI.00376-13.
    • (2013) J Virol , vol.87 , pp. 8687-8696
    • Gautam, D.1    Bridge, E.2
  • 68
    • 0035929667 scopus 로고    scopus 로고
    • DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex
    • Trujillo KM, Sung P. 2001. DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex. J Biol Chem 276: 35458-35464. http://dx.doi.org/10.1074/jbc.M105482200.
    • (2001) J Biol Chem , vol.276 , pp. 35458-35464
    • Trujillo, K.M.1    Sung, P.2
  • 69
    • 0035869155 scopus 로고    scopus 로고
    • DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways
    • de Jager M, Dronkert ML, Modesti M, Beerens CE, Kanaar R, van Gent DC. 2001. DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways. Nucleic Acids Res 29:1317-1325. http://dx.doi.org/10.1093/nar/29.6.1317.
    • (2001) Nucleic Acids Res , vol.29 , pp. 1317-1325
    • de Jager, M.1    Dronkert, M.L.2    Modesti, M.3    Beerens, C.E.4    Kanaar, R.5    van Gent, D.C.6
  • 70
    • 0032085295 scopus 로고    scopus 로고
    • The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks
    • Paull TT, Gellert M. 1998. The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks. Mol Cell 1:969-979. http://dx.doi.org/10.1016/S1097-2765(00)80097-0.
    • (1998) Mol Cell , vol.1 , pp. 969-979
    • Paull, T.T.1    Gellert, M.2
  • 71
    • 79955446411 scopus 로고    scopus 로고
    • Adenovirus core protein VII protects the viral genome from a DNA damage response at early times after infection
    • Karen KA, Hearing P. 2011. Adenovirus core protein VII protects the viral genome from a DNA damage response at early times after infection. J Virol 85:4135-4142. http://dx.doi.org/10.1128/JVI.02540-10.
    • (2011) J Virol , vol.85 , pp. 4135-4142
    • Karen, K.A.1    Hearing, P.2
  • 72
    • 34547686371 scopus 로고    scopus 로고
    • The cellular Mre11 protein interferes with adenovirus E4 mutant DNA replication
    • Mathew SS, Bridge E. 2007. The cellular Mre11 protein interferes with adenovirus E4 mutant DNA replication. Virology 365:346-355. http://dx.doi.org/10.1016/j.virol.2007.03.049.
    • (2007) Virology , vol.365 , pp. 346-355
    • Mathew, S.S.1    Bridge, E.2
  • 73
    • 34250894884 scopus 로고    scopus 로고
    • Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation
    • Baker A, Rohleder KJ, Hanakahi LA, Ketner G. 2007. Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation. J Virol 81:7034-7040. http://dx.doi.org/10.1128/JVI.00029-07.
    • (2007) J Virol , vol.81 , pp. 7034-7040
    • Baker, A.1    Rohleder, K.J.2    Hanakahi, L.A.3    Ketner, G.4
  • 75
    • 0033818902 scopus 로고    scopus 로고
    • Adeno-associated virus type 2 Rep78 induces apoptosis through caspase activation independently of p53
    • Schmidt M, Afione S, Kotin RM. 2000. Adeno-associated virus type 2 Rep78 induces apoptosis through caspase activation independently of p53. J Virol 74:9441-9450. http://dx.doi.org/10.1128/JVI.74.20.9441-9450.2000.
    • (2000) J Virol , vol.74 , pp. 9441-9450
    • Schmidt, M.1    Afione, S.2    Kotin, R.M.3
  • 77
    • 0035974901 scopus 로고    scopus 로고
    • Virus-mediated killing of cells that lack p53 activity
    • Raj K, Ogston P, Beard P. 2001. Virus-mediated killing of cells that lack p53 activity. Nature 412:914-917. http://dx.doi.org/10.1038/35091082.
    • (2001) Nature , vol.412 , pp. 914-917
    • Raj, K.1    Ogston, P.2    Beard, P.3
  • 78
    • 70350306544 scopus 로고    scopus 로고
    • Adeno-associated virus site-specific integration is mediated by proteins of the nonhomologous end-joining pathway
    • Daya S, Cortez N, Berns KI. 2009. Adeno-associated virus site-specific integration is mediated by proteins of the nonhomologous end-joining pathway. J Virol 83:11655-11664. http://dx.doi.org/10.1128/JVI.01040-09.
    • (2009) J Virol , vol.83 , pp. 11655-11664
    • Daya, S.1    Cortez, N.2    Berns, K.I.3
  • 79
    • 0022263759 scopus 로고
    • Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport
    • Babiss LE, Ginsberg HS, Darnell JE, Jr. 1985. Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport. Mol Cell Biol 5:2552-2558.
    • (1985) Mol Cell Biol , vol.5 , pp. 2552-2558
    • Babiss, L.E.1    Ginsberg, H.S.2    Darnell Jr., J.E.3
  • 80
    • 0022381043 scopus 로고
    • Adenovirus early region 4 encodes functions required for efficientDNAreplication, late gene expression, and host cell shutoff
    • Halbert DN, Cutt JR, Shenk T. 1985. Adenovirus early region 4 encodes functions required for efficientDNAreplication, late gene expression, and host cell shutoff. J Virol 56:250-257.
    • (1985) J Virol , vol.56 , pp. 250-257
    • Halbert, D.N.1    Cutt, J.R.2    Shenk, T.3
  • 81
    • 0024456615 scopus 로고
    • The adenovirus E1B 55 kd protein influences mRNA transport via an intranuclear effect on RNA metabolism
    • Leppard KN, Shenk T. 1989. The adenovirus E1B 55 kd protein influences mRNA transport via an intranuclear effect on RNA metabolism. EMBO J 8:2329-2336.
    • (1989) EMBO J , vol.8 , pp. 2329-2336
    • Leppard, K.N.1    Shenk, T.2
  • 82
    • 0023949464 scopus 로고
    • Adenovirus E1B 55-Mr polypeptide facilitates timely cytoplasmic accumulation of adeno-associated virus mRNAs
    • Samulski RJ, Shenk T. 1988. Adenovirus E1B 55-Mr polypeptide facilitates timely cytoplasmic accumulation of adeno-associated virus mRNAs. J Virol 62:206-210.
    • (1988) J Virol , vol.62 , pp. 206-210
    • Samulski, R.J.1    Shenk, T.2
  • 83
    • 33846118836 scopus 로고    scopus 로고
    • Adenovirus ubiquitin-protein ligase stimulates viral late mRNA nuclear export
    • Woo JL, Berk AJ. 2007. Adenovirus ubiquitin-protein ligase stimulates viral late mRNA nuclear export. J Virol 81:575-587. http://dx.doi.org/10.1128/JVI.01725-06.
    • (2007) J Virol , vol.81 , pp. 575-587
    • Woo, J.L.1    Berk, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.