Viral Single-Strand DNA Induces p53-Dependent Apoptosis in Human Embryonic Stem Cells

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Hirsch, Matthew L ^a   Fagan, B Matthew ^b   Dumitru, Raluca ^a   Bower, Jacquelyn J ^a   Yadav, Swati ^a   Porteus, Matthew H ^c   Pevny, Larysa H ^a   Samulski, R Jude ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; GAMMA HISTONE H2AX; HISTONE H2AX; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; PUMA PROTEIN; SERINE; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; H2AFX PROTEIN, HUMAN; HISTONE; MESSENGER RNA; TP53 PROTEIN, HUMAN;

ADENO ASSOCIATED VIRUS; APOPTOSIS; ARTICLE; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; DNA DAMAGE; DNA STRUCTURE; EMBRYO; EMBRYONIC STEM CELL; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PLURIPOTENT STEM CELL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SEROTYPE; SIGNAL TRANSDUCTION; TELOMERE; TETRAD REPEAT SEQUENCE; TRANSCRIPTION INITIATION; VIRUS REPLICATION; CELL CULTURE; CYTOLOGY; DNA REPLICATION; FIBROBLAST; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADENO-ASSOCIATED VIRUS; MIRIDAE;

APOPTOSIS; BLOTTING, WESTERN; CELLS, CULTURED; DEPENDOVIRUS; DNA DAMAGE; DNA REPLICATION; DNA, SINGLE-STRANDED; EMBRYONIC STEM CELLS; FIBROBLASTS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HISTONES; HUMANS; PHOSPHORYLATION; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84860589836     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027520     Document Type: Article

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