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Volumn 22, Issue 1, 2015, Pages 29-47

The C-terminal module IV of connective tissue growth factor, through EGFR/Nox1 signaling, activates the NF-κB pathway and proinflammatory factors in vascular smooth muscle cells

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE; OXYGEN; PARTHENOLIDE; PHENYLEPHRINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; SUPEROXIDE; CTGF PROTEIN, MOUSE; OXIDOREDUCTASE;

EID: 84919361015     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2013.5500     Document Type: Article
Times cited : (32)

References (72)
  • 5
    • 77953535497 scopus 로고    scopus 로고
    • Oxidative stress and hypertension: Current concepts
    • Briones AM and Touyz RM. Oxidative stress and hypertension: current concepts. Curr Hypertens Rep 12: 135-142, 2010.
    • (2010) Curr Hypertens Rep , vol.12 , pp. 135-142
    • Briones, A.M.1    Touyz, R.M.2
  • 7
    • 33947126121 scopus 로고    scopus 로고
    • Cytotoxicity of TNFalpha is regulated by integrin-mediated matrix signaling
    • Chen CC, Young JL, Monzon RI, Chen N, Todorović V, and Lau LF. Cytotoxicity of TNFalpha is regulated by integrin-mediated matrix signaling. EMBO J 26: 1257-1267, 2007.
    • (2007) EMBO J , vol.26 , pp. 1257-1267
    • Chen, C.C.1    Young, J.L.2    Monzon, R.I.3    Chen, N.4    Todorović, V.5    Lau, L.F.6
  • 10
    • 33749395428 scopus 로고    scopus 로고
    • RhoA mediates angiotensin II-induced phospho-Ser536 nuclear factor kappaB/RelA subunit exchange on the interleukin-6 promoter in VSMCs
    • Cui R, Tieu B, Recinos A, Tilton RG, and Brasier AR. RhoA mediates angiotensin II-induced phospho-Ser536 nuclear factor kappaB/RelA subunit exchange on the interleukin-6 promoter in VSMCs. Circ Res 99: 723-730, 2006.
    • (2006) Circ Res , vol.99 , pp. 723-730
    • Cui, R.1    Tieu, B.2    Recinos, A.3    Tilton, R.G.4    Brasier, A.R.5
  • 11
    • 42549131051 scopus 로고    scopus 로고
    • Connective tissue growth factor: Structure-function relationships of a mosaic, multifunctional protein
    • De Winter P, Leoni P, and Abraham D. Connective tissue growth factor: structure-function relationships of a mosaic, multifunctional protein. Growth Factors 26: 80-91, 2008.
    • (2008) Growth Factors , vol.26 , pp. 80-91
    • De Winter, P.1    Leoni, P.2    Abraham, D.3
  • 12
    • 34047219789 scopus 로고    scopus 로고
    • Measurement of reactive oxygen species in cardiovascular studies
    • Dikalov S, Griendling KK, and Harrison DG. Measurement of reactive oxygen species in cardiovascular studies. Hypertension 49: 717-727, 2007.
    • (2007) Hypertension , vol.49 , pp. 717-727
    • Dikalov, S.1    Griendling, K.K.2    Harrison, D.G.3
  • 13
    • 33645845521 scopus 로고    scopus 로고
    • The epidermal growth factor receptors and their family of ligands: Their putative role in atherogenesis
    • Dreux AC, Lamb DJ, Modjtahedi H, and Ferns GA. The epidermal growth factor receptors and their family of ligands: their putative role in atherogenesis. Atherosclerosis 186: 38-53, 2006.
    • (2006) Atherosclerosis , vol.186 , pp. 38-53
    • Dreux, A.C.1    Lamb, D.J.2    Modjtahedi, H.3    Ferns, G.A.4
  • 14
    • 79957890939 scopus 로고    scopus 로고
    • Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets
    • Drummond GR, Selemidis S, Griendling KK, and Sobey CG. Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat Rev Drug Discov 10: 453-471, 2011.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 453-471
    • Drummond, G.R.1    Selemidis, S.2    Griendling, K.K.3    Sobey, C.G.4
  • 16
    • 2542424673 scopus 로고    scopus 로고
    • Angiotensin II, via AT1 and AT2 receptors and NF-kappaB pathway, regulates the inflammatory response in unilateral ureteral obstruction
    • Esteban V, Lorenzo O, Rupérez M, Suzuki Y, and Ruiz-Ortega M. Angiotensin II, via AT1 and AT2 receptors and NF-kappaB pathway, regulates the inflammatory response in unilateral ureteral obstruction. J Am Soc Nephrol 15: 1514-1529, 2004.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1514-1529
    • Esteban, V.1    Lorenzo, O.2    Rupérez, M.3    Suzuki, Y.4    Ruiz-Ortega, M.5
  • 18
    • 84908119714 scopus 로고    scopus 로고
    • Inhibition of connective tissue growth factor suppresses hepatic stellate cell activation in vitro and prevents liver fibrosis in vivo
    • Hao C, Xie Y, Peng M, Ma L, Zhou Y, Zhang Y, Kang W, Wang J, Bai X, Wang P, and Jia Z. Inhibition of connective tissue growth factor suppresses hepatic stellate cell activation in vitro and prevents liver fibrosis in vivo. Clin Exp Med 14: 141-150, 2014.
    • (2014) Clin Exp Med , vol.14 , pp. 141-150
    • Hao, C.1    Xie, Y.2    Peng, M.3    Ma, L.4    Zhou, Y.5    Zhang, Y.6    Kang, W.7    Wang, J.8    Bai, X.9    Wang, P.10    Jia, Z.11
  • 20
    • 0033571108 scopus 로고    scopus 로고
    • The antiinflammatorysesquiterpene lactone Parthenolide inhibits NF-kappa B by targeting the i kappa B kinase complex
    • Hehner SP, Hofmann TG, Droge W, and Schmitz ML. The antiinflammatorysesquiterpene lactone Parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex. J Immunol 163: 5617-5623, 1999.
    • (1999) J Immunol , vol.163 , pp. 5617-5623
    • Hehner, S.P.1    Hofmann, T.G.2    Droge, W.3    Schmitz, M.L.4
  • 21
    • 84879377766 scopus 로고    scopus 로고
    • Connective tissue growth factor induces osteogenic differentiation of vascular smooth muscle cells through ERK signaling
    • Huang J, Huang H, Wu M, Li J, Xie H, Zhou H, Liao E, and Peng Y. Connective tissue growth factor induces osteogenic differentiation of vascular smooth muscle cells through ERK signaling. Int J Mol Med 32: 423-429, 2013.
    • (2013) Int J Mol Med , vol.32 , pp. 423-429
    • Huang, J.1    Huang, H.2    Wu, M.3    Li, J.4    Xie, H.5    Zhou, H.6    Liao, E.7    Peng, Y.8
  • 22
    • 67649231054 scopus 로고    scopus 로고
    • Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivo
    • Juric V, Chen CC, and Lau LF. Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivo. Mol Cell Biol 29: 3266-3279, 2009.
    • (2009) Mol Cell Biol , vol.29 , pp. 3266-3279
    • Juric, V.1    Chen, C.C.2    Lau, L.F.3
  • 23
    • 0037143616 scopus 로고    scopus 로고
    • Angiotensin II-induced cardiac hypertrophy and hypertension are attenuated by epidermal growth factor receptor antisense
    • Kagiyama S, Eguchi S, Frank GD, Inagami T, Zhang YC, and Phillips MI. Angiotensin II-induced cardiac hypertrophy and hypertension are attenuated by epidermal growth factor receptor antisense. Circulation 106: 909-912, 2002.
    • (2002) Circulation , vol.106 , pp. 909-912
    • Kagiyama, S.1    Eguchi, S.2    Frank, G.D.3    Inagami, T.4    Zhang, Y.C.5    Phillips, M.I.6
  • 24
    • 49549122634 scopus 로고    scopus 로고
    • Molecular insights into connective tissue growth factor action in rat pancreatic stellate cells
    • Karger A, Fitzner B, Brock p, Sparmann G, Emmrich J, Liebe S, and Jaster R. Molecular insights into connective tissue growth factor action in rat pancreatic stellate cells. Cell Signal 20: 1865-1872, 2008.
    • (2008) Cell Signal , vol.20 , pp. 1865-1872
    • Karger, A.1    Fitzner, B.2    Brock, P.3    Sparmann, G.4    Emmrich, J.5    Liebe, S.6    Jaster, R.7
  • 25
    • 84878975251 scopus 로고    scopus 로고
    • Matricellular protein CCN1 promotes regression of liver fibrosis through induction of cellular senescence in hepatic myofibroblasts
    • Kim KH, Chen CC, Monzon RI, and Lau LF. Matricellular protein CCN1 promotes regression of liver fibrosis through induction of cellular senescence in hepatic myofibroblasts. Mol Cell Biol 33: 2078-2090, 2013.
    • (2013) Mol Cell Biol , vol.33 , pp. 2078-2090
    • Kim, K.H.1    Chen, C.C.2    Monzon, R.I.3    Lau, L.F.4
  • 29
    • 84861062943 scopus 로고    scopus 로고
    • Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system
    • Lasségue B, San Martín A, and Griendling KK. Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circ Res 110: 1364-1390, 2012.
    • (2012) Circ Res , vol.110 , pp. 1364-1390
    • Lasségue, B.1    San Martín, A.2    Griendling, K.K.3
  • 30
    • 52049110957 scopus 로고    scopus 로고
    • Assessment of superoxide production and NADPH oxidase activity by HPLC analysis of dihydroethidium oxidation products
    • Laurindo FR, Fernandes DC, and Santos CX. Assessment of superoxide production and NADPH oxidase activity by HPLC analysis of dihydroethidium oxidation products. Methods Enzymol 441: 237-260, 2008.
    • (2008) Methods Enzymol , vol.441 , pp. 237-260
    • Laurindo, F.R.1    Fernandes, D.C.2    Santos, C.X.3
  • 31
    • 80055014533 scopus 로고    scopus 로고
    • CCN2/decorin interactions: A novel approach to combating fibrosis?
    • Leask A. CCN2/decorin interactions: a novel approach to combating fibrosis? J Cell Commun Signal 5: 249-250, 2011.
    • (2011) J Cell Commun Signal , vol.5 , pp. 249-250
    • Leask, A.1
  • 32
    • 33747873520 scopus 로고    scopus 로고
    • Role of connective tissue growth factor (CTGF) module 4 in regulating epithelial mesenchymal transition in HK-2 cells
    • Liu BC, Zhang JD, Zhang XL, Wu GQ, and Li MX. Role of connective tissue growth factor (CTGF) module 4 in regulating epithelial mesenchymal transition in HK-2 cells. Clin Chim Acta 373: 144-150, 2006.
    • (2006) Clin Chim Acta , vol.373 , pp. 144-150
    • Liu, B.C.1    Zhang, J.D.2    Zhang, X.L.3    Wu, G.Q.4    Li, M.X.5
  • 33
    • 77956816714 scopus 로고    scopus 로고
    • Trimetazidine inhibits pressure overload-induced cardiac fibrosis through NADPH oxidase-ROS-CTGF pathway
    • Liu X, Gai Y, Liu F, Gao W, Zhang Y, Xu M, and Li Z. Trimetazidine inhibits pressure overload-induced cardiac fibrosis through NADPH oxidase-ROS-CTGF pathway. Cardiovasc Res 88: 150-158, 2010.
    • (2010) Cardiovasc Res , vol.88 , pp. 150-158
    • Liu, X.1    Gai, Y.2    Liu, F.3    Gao, W.4    Zhang, Y.5    Xu, M.6    Li, Z.7
  • 35
    • 78650571743 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells
    • Markiewicz M, Nakerakanti SS, Kapanadze B, Ghatnekar A, and Trojanowska M. Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells. Microcirculation 18: 1-11, 2011.
    • (2011) Microcirculation , vol.18 , pp. 1-11
    • Markiewicz, M.1    Nakerakanti, S.S.2    Kapanadze, B.3    Ghatnekar, A.4    Trojanowska, M.5
  • 38
    • 75449099482 scopus 로고    scopus 로고
    • Diabetes and microvascular pathophysiology: Role of epidermal growth factor receptor tyrosine kinase
    • Matrougui K. Diabetes and microvascular pathophysiology: role of epidermal growth factor receptor tyrosine kinase. Diabetes Metab Res Rev 26: 13-16, 2010.
    • (2010) Diabetes Metab Res Rev , vol.26 , pp. 13-16
    • Matrougui, K.1
  • 39
    • 84874942046 scopus 로고    scopus 로고
    • CCN2 exerts direct cytoprotective actions in adult cardiac myocytes by activation of the PI3-kinase/Akt/GSK-3b signaling pathway
    • Moe IT, Pham TA, Hagelin EM, Ahmed MS, and Attramadal H. CCN2 exerts direct cytoprotective actions in adult cardiac myocytes by activation of the PI3-kinase/Akt/GSK-3b signaling pathway. J Cell Commun Signal 7: 31-47, 2012.
    • (2012) J Cell Commun Signal , vol.7 , pp. 31-47
    • Moe, I.T.1    Pham, T.A.2    Hagelin, E.M.3    Ahmed, M.S.4    Attramadal, H.5
  • 40
    • 34247093334 scopus 로고    scopus 로고
    • Nitric oxide and the vascular endothelium
    • Moncada S and Higgs EA. Nitric oxide and the vascular endothelium. Handb Exp Pharmacol (176 Pt 1): 213-254, 2006.
    • (2006) Handb Exp Pharmacol , vol.176 , pp. 213-254
    • Moncada, S.1    Higgs, E.A.2
  • 41
    • 78650894319 scopus 로고    scopus 로고
    • Crosstalk of reactive oxygen species and NF-jB signaling
    • Morgan MJ and Liu ZG. Crosstalk of reactive oxygen species and NF-jB signaling. Cell Res 21: 103-115, 2011.
    • (2011) Cell Res , vol.21 , pp. 103-115
    • Morgan, M.J.1    Liu, Z.G.2
  • 42
    • 0032794692 scopus 로고    scopus 로고
    • Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model
    • Mori T, Kawara S, Shinozaki M, Hayashi N, Kakinuma T, Igarashi A, Takigawa M, Nakanishi T, and Takehara K. Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: a mouse fibrosis model. J Cell Physiol 181: 153-159, 1999.
    • (1999) J Cell Physiol , vol.181 , pp. 153-159
    • Mori, T.1    Kawara, S.2    Shinozaki, M.3    Hayashi, N.4    Kakinuma, T.5    Igarashi, A.6    Takigawa, M.7    Nakanishi, T.8    Takehara, K.9
  • 43
    • 78649357316 scopus 로고    scopus 로고
    • Is oxidative stress a therapeutic target in cardiovascular disease?
    • Münzel T, Gori T, Bruno RM, and Taddei S. Is oxidative stress a therapeutic target in cardiovascular disease? Eur Heart J 31: 2741-2748, 2010.
    • (2010) Eur Heart J , vol.31 , pp. 2741-2748
    • Münzel, T.1    Gori, T.2    Bruno, R.M.3    Taddei, S.4
  • 47
    • 0347915577 scopus 로고    scopus 로고
    • CCN proteins: Multifunctional signaling regulators
    • Perbal B. CCN proteins: multifunctional signaling regulators. Lancet 363: 62-64, 2004.
    • (2004) Lancet , vol.363 , pp. 62-64
    • Perbal, B.1
  • 48
    • 70849136597 scopus 로고    scopus 로고
    • Connective tissue growth factor-(CTGF, CCN2) - A marker mediator and therapeutic target for renal fibrosis
    • Phanish MK, Winn SK, and Dockrell ME. Connective tissue growth factor-(CTGF, CCN2)-a marker mediator and therapeutic target for renal fibrosis. Nephron Exp Nephrol 114: e83-e92, 2010.
    • (2010) Nephron Exp Nephrol , vol.114 , pp. e83-e92
    • Phanish, M.K.1    Winn, S.K.2    Dockrell, M.E.3
  • 50
    • 84875367781 scopus 로고    scopus 로고
    • Connective tissue growth factor (CCN2) in blood vessels
    • Ponticos M. Connective tissue growth factor (CCN2) in blood vessels. Vascul Pharmacol 58: 189-193, 2013.
    • (2013) Vascul Pharmacol , vol.58 , pp. 189-193
    • Ponticos, M.1
  • 53
    • 22744459775 scopus 로고    scopus 로고
    • Endothelin-1, via ETA receptor and independently of transforming growth factor-beta, increases the connective tissue growth factor in vascular smooth muscle cells
    • Rodriguez-Vita J, Ruiz-Ortega M, Rupérez M, Esteban V, Sanchez-López E, Plaza JJ, and Egido J. Endothelin-1, via ETA receptor and independently of transforming growth factor-beta, increases the connective tissue growth factor in vascular smooth muscle cells. Circ Res 97: 125-134, 2005.
    • (2005) Circ Res , vol.97 , pp. 125-134
    • Rodriguez-Vita, J.1    Ruiz-Ortega, M.2    Rupérez, M.3    Esteban, V.4    Sanchez-López, E.5    Plaza, J.J.6    Egido, J.7
  • 54
    • 24144483086 scopus 로고    scopus 로고
    • Angiotensin II and reactive oxygens pecies
    • Ruiz-Ortega M and Ortiz A. Angiotensin II and reactive oxygens pecies. Antioxid Redox Signal 7: 1258-1260, 2005.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1258-1260
    • Ruiz-Ortega, M.1    Ortiz, A.2
  • 61
    • 34247136835 scopus 로고    scopus 로고
    • Vascular inflammation in hypertension and diabetes: Molecular mechanisms and therapeutic interventions
    • Savoia C and Schiffrin EL. Vascular inflammation in hypertension and diabetes: molecular mechanisms and therapeutic interventions. Clin Sci (Lond) 112: 375-384, 2007.
    • (2007) Clin Sci (Lond) , vol.112 , pp. 375-384
    • Savoia, C.1    Schiffrin, E.L.2
  • 62
    • 84894062402 scopus 로고    scopus 로고
    • Role of epidermal growth factor receptor in vascular structure and function
    • Schreier B, Gekle M, and Grossmann C. Role of epidermal growth factor receptor in vascular structure and function. Curr Opin Nephrol Hypertens 23: 113-121, 2014.
    • (2014) Curr Opin Nephrol Hypertens , vol.23 , pp. 113-121
    • Schreier, B.1    Gekle, M.2    Grossmann, C.3
  • 64
    • 80054704273 scopus 로고    scopus 로고
    • NADPH oxidases in cardiovascular disease: Insights from in vivo models and clinical studies
    • Sirker A, Zhang M, and Shah AM. NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies. Basic Res Cardiol 106: 735-747, 2011.
    • (2011) Basic Res Cardiol , vol.106 , pp. 735-747
    • Sirker, A.1    Zhang, M.2    Shah, A.M.3
  • 65
    • 84857132548 scopus 로고    scopus 로고
    • Diabetes mellitus and vascular endothelial dysfunction: Current perspectives
    • Tousoulis D, Kampoli AM, and Stefanadis C. Diabetes mellitus and vascular endothelial dysfunction: current perspectives. Curr Vasc Pharmacol 10: 19-32, 2012.
    • (2012) Curr Vasc Pharmacol , vol.10 , pp. 19-32
    • Tousoulis, D.1    Kampoli, A.M.2    Stefanadis, C.3
  • 69
    • 82255171911 scopus 로고    scopus 로고
    • Oxidative stress and vascular damage in hypertension: Role of angiotensin II
    • Virdis A, Duranti E, and Taddei S. Oxidative stress and vascular damage in hypertension: role of angiotensin II. Int J Hypertens 916310, 2011. DOI: 10.4061/2011/916310.
    • (2011) Int J Hypertens , pp. 916310
    • Virdis, A.1    Duranti, E.2    Taddei, S.3
  • 70
    • 77249106466 scopus 로고    scopus 로고
    • Regulation of pro-inflammatory and pro-fibrotic factors by CCN2/CTGF in H9c2 cardiomyocytes
    • Wang X, McLennan SV, Allen TJ, and Twigg SM. Regulation of pro-inflammatory and pro-fibrotic factors by CCN2/CTGF in H9c2 cardiomyocytes. J Cell Commun Signal 4: 15-23, 2010.
    • (2010) J Cell Commun Signal , vol.4 , pp. 15-23
    • Wang, X.1    McLennan, S.V.2    Allen, T.J.3    Twigg, S.M.4
  • 71
    • 79952445768 scopus 로고    scopus 로고
    • Knockdown of connective tissue growth factor by plasmidbased short hairpin RNA prevented pulmonary vascular remodeling in cigarette smoke-exposed rats
    • Wang R, Xu YJ, Liu XS, Zeng DX, and Xiang M. Knockdown of connective tissue growth factor by plasmidbased short hairpin RNA prevented pulmonary vascular remodeling in cigarette smoke-exposed rats. Arch Biochem Biophys 508: 93-100, 2011.
    • (2011) Arch Biochem Biophys , vol.508 , pp. 93-100
    • Wang, R.1    Xu, Y.J.2    Liu, X.S.3    Zeng, D.X.4    Xiang, M.5
  • 72
    • 59849114489 scopus 로고    scopus 로고
    • Signal transduction involved in CTGF-induced production of chemokines in mesangial cells
    • Wu S-H, Lu C, Dong L, and Chen Z-Q. Signal transduction involved in CTGF-induced production of chemokines in mesangial cells. Growth Factors 26: 192-200, 2008.
    • (2008) Growth Factors , vol.26 , pp. 192-200
    • Wu, S.-H.1    Lu, C.2    Dong, L.3    Chen, Z.-Q.4


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