-
1
-
-
79955072907
-
Mechanisms of novel cardioprotective functions of CCN2/CTGF in myocardial ischemiareperfusion injury
-
Ahmed MS, Gravning J, Martinov VN, von Lueder TG, Edvardsen T, Czibik G, Moe IT, Vinge LE, Øie E, Valen G, and Attramadal H. Mechanisms of novel cardioprotective functions of CCN2/CTGF in myocardial ischemiareperfusion injury. Am J Physiol Heart Circ Physiol 300: H1291-H1302, 2011.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.300
, pp. H1291-H1302
-
-
Ahmed, M.S.1
Gravning, J.2
Martinov, V.N.3
Von Lueder, T.G.4
Edvardsen, T.5
Czibik, G.6
Moe, I.T.7
Vinge, L.E.8
Øie, E.9
Valen, G.10
Attramadal, H.11
-
2
-
-
80052263264
-
Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling
-
Al Ghouleh I, Khoo NK, Knaus UG, Griendling KK, Touyz RM, Thannickal VJ, Barchowsky A, Nauseef WM, Kelley EE, Bauer PM, Darley-Usmar V, Shiva S, Cifuentes-Pagano E, Freeman BA, Gladwin MT, and Pagano PJ. Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling. Free Radic Biol Med 51: 1271-1288, 2011.
-
(2011)
Free Radic Biol Med
, vol.51
, pp. 1271-1288
-
-
Al Ghouleh, I.1
Khoo, N.K.2
Knaus, U.G.3
Griendling, K.K.4
Touyz, R.M.5
Thannickal, V.J.6
Barchowsky, A.7
Nauseef, W.M.8
Kelley, E.E.9
Bauer, P.M.10
Darley-Usmar, V.11
Shiva, S.12
Cifuentes-Pagano, E.13
Freeman, B.A.14
Gladwin, M.T.15
Pagano, P.J.16
-
3
-
-
84886077894
-
Oxidative stress modulates vascular smooth muscle cell phenotype via CTGF in thoracic aortic aneurysm
-
Branchetti E, Poggio P, Sainger R, Shang E, Grau JB, Jackson BM, Lai EK, Parmacek MS, Gorman RC, Gorman JH, Bavaria JE, and Ferrari G. Oxidative stress modulates vascular smooth muscle cell phenotype via CTGF in thoracic aortic aneurysm. Cardiovasc Res 100: 316-324, 2013.
-
(2013)
Cardiovasc Res
, vol.100
, pp. 316-324
-
-
Branchetti, E.1
Poggio, P.2
Sainger, R.3
Shang, E.4
Grau, J.B.5
Jackson, B.M.6
Lai, E.K.7
Parmacek, M.S.8
Gorman, R.C.9
Gorman, J.H.10
Bavaria, J.E.11
Ferrari, G.12
-
4
-
-
67649837051
-
Atorvastatin prevents angiotensin II-induced vascular remodeling and oxidative stress
-
Briones AM, Rodríguez-Criado N, Hernanz R, García-Redondo AB, Rodrigues-Díez RR, Alonso MJ, Egido J, Ruiz-Ortega M, and Salaices M. Atorvastatin prevents angiotensin II-induced vascular remodeling and oxidative stress. Hypertension 54: 142-149, 2009.
-
(2009)
Hypertension
, vol.54
, pp. 142-149
-
-
Briones, A.M.1
Rodríguez-Criado, N.2
Hernanz, R.3
García-Redondo, A.B.4
Rodrigues-Díez, R.R.5
Alonso, M.J.6
Egido, J.7
Ruiz-Ortega, M.8
Salaices, M.9
-
5
-
-
77953535497
-
Oxidative stress and hypertension: Current concepts
-
Briones AM and Touyz RM. Oxidative stress and hypertension: current concepts. Curr Hypertens Rep 12: 135-142, 2010.
-
(2010)
Curr Hypertens Rep
, vol.12
, pp. 135-142
-
-
Briones, A.M.1
Touyz, R.M.2
-
6
-
-
84872491620
-
Nox4 modulates collagen production stimulated by transforming growth factor b1 in vivo and in vitro
-
Chan EC, Peshavariya HM, Liu GS, Jiang F, Lim SY, and Dusting GJ. Nox4 modulates collagen production stimulated by transforming growth factor b1 in vivo and in vitro. Biochem Biophys Res Commun 430: 918-925, 2013.
-
(2013)
Biochem Biophys Res Commun
, vol.430
, pp. 918-925
-
-
Chan, E.C.1
Peshavariya, H.M.2
Liu, G.S.3
Jiang, F.4
Lim, S.Y.5
Dusting, G.J.6
-
7
-
-
33947126121
-
Cytotoxicity of TNFalpha is regulated by integrin-mediated matrix signaling
-
Chen CC, Young JL, Monzon RI, Chen N, Todorović V, and Lau LF. Cytotoxicity of TNFalpha is regulated by integrin-mediated matrix signaling. EMBO J 26: 1257-1267, 2007.
-
(2007)
EMBO J
, vol.26
, pp. 1257-1267
-
-
Chen, C.C.1
Young, J.L.2
Monzon, R.I.3
Chen, N.4
Todorović, V.5
Lau, L.F.6
-
8
-
-
18244391728
-
Connective tissue growth factor is overexpressed in complicated atherosclerotic plaques and induces mononuclear cell chemotaxis in vitro
-
Cicha I, Yilmaz A, Klein M, Raithel D, Brigstock DR, Daniel WG, Goppelt-Struebe M, and Garlichs CD. Connective tissue growth factor is overexpressed in complicated atherosclerotic plaques and induces mononuclear cell chemotaxis in vitro. Arterioscler Thromb Vasc Biol 25: 1008-1013, 2005.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 1008-1013
-
-
Cicha, I.1
Yilmaz, A.2
Klein, M.3
Raithel, D.4
Brigstock, D.R.5
Daniel, W.G.6
Goppelt-Struebe, M.7
Garlichs, C.D.8
-
9
-
-
84870056994
-
Thrombospondin-1 regulates blood flow via CD47 receptor-mediated activation of NADPH oxidase 1
-
Csányi G1, Yao M, Rodríguez AI, Al Ghouleh I, Sharifi-Sanjani M, Frazziano G, Huang X, Kelley EE, Isenberg JS, and Pagano PJ. Thrombospondin-1 regulates blood flow via CD47 receptor-mediated activation of NADPH oxidase 1. Arterioscler Thromb Vasc Biol 32: 2966-2973, 2012.
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 2966-2973
-
-
Csányi, G.L.1
Yao, M.2
Rodríguez, A.I.3
Al Ghouleh, I.4
Sharifi-Sanjani, M.5
Frazziano, G.6
Huang, X.7
Kelley, E.E.8
Isenberg, J.S.9
Pagano, P.J.10
-
10
-
-
33749395428
-
RhoA mediates angiotensin II-induced phospho-Ser536 nuclear factor kappaB/RelA subunit exchange on the interleukin-6 promoter in VSMCs
-
Cui R, Tieu B, Recinos A, Tilton RG, and Brasier AR. RhoA mediates angiotensin II-induced phospho-Ser536 nuclear factor kappaB/RelA subunit exchange on the interleukin-6 promoter in VSMCs. Circ Res 99: 723-730, 2006.
-
(2006)
Circ Res
, vol.99
, pp. 723-730
-
-
Cui, R.1
Tieu, B.2
Recinos, A.3
Tilton, R.G.4
Brasier, A.R.5
-
11
-
-
42549131051
-
Connective tissue growth factor: Structure-function relationships of a mosaic, multifunctional protein
-
De Winter P, Leoni P, and Abraham D. Connective tissue growth factor: structure-function relationships of a mosaic, multifunctional protein. Growth Factors 26: 80-91, 2008.
-
(2008)
Growth Factors
, vol.26
, pp. 80-91
-
-
De Winter, P.1
Leoni, P.2
Abraham, D.3
-
12
-
-
34047219789
-
Measurement of reactive oxygen species in cardiovascular studies
-
Dikalov S, Griendling KK, and Harrison DG. Measurement of reactive oxygen species in cardiovascular studies. Hypertension 49: 717-727, 2007.
-
(2007)
Hypertension
, vol.49
, pp. 717-727
-
-
Dikalov, S.1
Griendling, K.K.2
Harrison, D.G.3
-
13
-
-
33645845521
-
The epidermal growth factor receptors and their family of ligands: Their putative role in atherogenesis
-
Dreux AC, Lamb DJ, Modjtahedi H, and Ferns GA. The epidermal growth factor receptors and their family of ligands: their putative role in atherogenesis. Atherosclerosis 186: 38-53, 2006.
-
(2006)
Atherosclerosis
, vol.186
, pp. 38-53
-
-
Dreux, A.C.1
Lamb, D.J.2
Modjtahedi, H.3
Ferns, G.A.4
-
14
-
-
79957890939
-
Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets
-
Drummond GR, Selemidis S, Griendling KK, and Sobey CG. Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat Rev Drug Discov 10: 453-471, 2011.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 453-471
-
-
Drummond, G.R.1
Selemidis, S.2
Griendling, K.K.3
Sobey, C.G.4
-
15
-
-
0141649447
-
Effect of simultaneous blockade of AT1 and AT2 receptors on the NF-jB pathway and renal inflammatory response
-
Esteban V, Ruperez M, Rodriguez-Vita J, Sanchez-López E, Mezzano S, Plaza JJ, Egido J, and Ruiz-Ortega M. Effect of simultaneous blockade of AT1 and AT2 receptors on the NF-jB pathway and renal inflammatory response. Kidney Int 64: S33-S38, 2003.
-
(2003)
Kidney Int
, vol.64
, pp. S33-S38
-
-
Esteban, V.1
Ruperez, M.2
Rodriguez-Vita, J.3
Sanchez-López, E.4
Mezzano, S.5
Plaza, J.J.6
Egido, J.7
Ruiz-Ortega, M.8
-
16
-
-
2542424673
-
Angiotensin II, via AT1 and AT2 receptors and NF-kappaB pathway, regulates the inflammatory response in unilateral ureteral obstruction
-
Esteban V, Lorenzo O, Rupérez M, Suzuki Y, and Ruiz-Ortega M. Angiotensin II, via AT1 and AT2 receptors and NF-kappaB pathway, regulates the inflammatory response in unilateral ureteral obstruction. J Am Soc Nephrol 15: 1514-1529, 2004.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 1514-1529
-
-
Esteban, V.1
Lorenzo, O.2
Rupérez, M.3
Suzuki, Y.4
Ruiz-Ortega, M.5
-
17
-
-
84871416039
-
Myocardial connective tissue growth factor (CCN2/CTGF) attenuates left ventricular remodeling after myocardial infarction
-
Gravning J, Ørn S, Kaasbøll OJ, Martinov VN, Manhenke C, Dickstein K, Edvardsen T, Attramadal H, and Ahmed MS. Myocardial connective tissue growth factor (CCN2/CTGF) attenuates left ventricular remodeling after myocardial infarction. PLoS One 7: e52120, 2012.
-
(2012)
PLoS One
, vol.7
-
-
Gravning, J.1
Ørn, S.2
Kaasbøll, O.J.3
Martinov, V.N.4
Manhenke, C.5
Dickstein, K.6
Edvardsen, T.7
Attramadal, H.8
Ahmed, M.S.9
-
18
-
-
84908119714
-
Inhibition of connective tissue growth factor suppresses hepatic stellate cell activation in vitro and prevents liver fibrosis in vivo
-
Hao C, Xie Y, Peng M, Ma L, Zhou Y, Zhang Y, Kang W, Wang J, Bai X, Wang P, and Jia Z. Inhibition of connective tissue growth factor suppresses hepatic stellate cell activation in vitro and prevents liver fibrosis in vivo. Clin Exp Med 14: 141-150, 2014.
-
(2014)
Clin Exp Med
, vol.14
, pp. 141-150
-
-
Hao, C.1
Xie, Y.2
Peng, M.3
Ma, L.4
Zhou, Y.5
Zhang, Y.6
Kang, W.7
Wang, J.8
Bai, X.9
Wang, P.10
Jia, Z.11
-
19
-
-
42249092488
-
Connective tissue growth factor induces cardiac hypertrophy through Akt signaling
-
Hayata N, Fujio Y, Yamamoto Y, Iwakura T, Obana M, Takai M, Mohri T, Nonen S, Maeda M, and Azuma J. Connective tissue growth factor induces cardiac hypertrophy through Akt signaling. Biochem Biophys Res Commun 37: 274-278, 2008.
-
(2008)
Biochem Biophys Res Commun
, vol.37
, pp. 274-278
-
-
Hayata, N.1
Fujio, Y.2
Yamamoto, Y.3
Iwakura, T.4
Obana, M.5
Takai, M.6
Mohri, T.7
Nonen, S.8
Maeda, M.9
Azuma, J.10
-
20
-
-
0033571108
-
The antiinflammatorysesquiterpene lactone Parthenolide inhibits NF-kappa B by targeting the i kappa B kinase complex
-
Hehner SP, Hofmann TG, Droge W, and Schmitz ML. The antiinflammatorysesquiterpene lactone Parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex. J Immunol 163: 5617-5623, 1999.
-
(1999)
J Immunol
, vol.163
, pp. 5617-5623
-
-
Hehner, S.P.1
Hofmann, T.G.2
Droge, W.3
Schmitz, M.L.4
-
21
-
-
84879377766
-
Connective tissue growth factor induces osteogenic differentiation of vascular smooth muscle cells through ERK signaling
-
Huang J, Huang H, Wu M, Li J, Xie H, Zhou H, Liao E, and Peng Y. Connective tissue growth factor induces osteogenic differentiation of vascular smooth muscle cells through ERK signaling. Int J Mol Med 32: 423-429, 2013.
-
(2013)
Int J Mol Med
, vol.32
, pp. 423-429
-
-
Huang, J.1
Huang, H.2
Wu, M.3
Li, J.4
Xie, H.5
Zhou, H.6
Liao, E.7
Peng, Y.8
-
22
-
-
67649231054
-
Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivo
-
Juric V, Chen CC, and Lau LF. Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivo. Mol Cell Biol 29: 3266-3279, 2009.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 3266-3279
-
-
Juric, V.1
Chen, C.C.2
Lau, L.F.3
-
23
-
-
0037143616
-
Angiotensin II-induced cardiac hypertrophy and hypertension are attenuated by epidermal growth factor receptor antisense
-
Kagiyama S, Eguchi S, Frank GD, Inagami T, Zhang YC, and Phillips MI. Angiotensin II-induced cardiac hypertrophy and hypertension are attenuated by epidermal growth factor receptor antisense. Circulation 106: 909-912, 2002.
-
(2002)
Circulation
, vol.106
, pp. 909-912
-
-
Kagiyama, S.1
Eguchi, S.2
Frank, G.D.3
Inagami, T.4
Zhang, Y.C.5
Phillips, M.I.6
-
24
-
-
49549122634
-
Molecular insights into connective tissue growth factor action in rat pancreatic stellate cells
-
Karger A, Fitzner B, Brock p, Sparmann G, Emmrich J, Liebe S, and Jaster R. Molecular insights into connective tissue growth factor action in rat pancreatic stellate cells. Cell Signal 20: 1865-1872, 2008.
-
(2008)
Cell Signal
, vol.20
, pp. 1865-1872
-
-
Karger, A.1
Fitzner, B.2
Brock, P.3
Sparmann, G.4
Emmrich, J.5
Liebe, S.6
Jaster, R.7
-
25
-
-
84878975251
-
Matricellular protein CCN1 promotes regression of liver fibrosis through induction of cellular senescence in hepatic myofibroblasts
-
Kim KH, Chen CC, Monzon RI, and Lau LF. Matricellular protein CCN1 promotes regression of liver fibrosis through induction of cellular senescence in hepatic myofibroblasts. Mol Cell Biol 33: 2078-2090, 2013.
-
(2013)
Mol Cell Biol
, vol.33
, pp. 2078-2090
-
-
Kim, K.H.1
Chen, C.C.2
Monzon, R.I.3
Lau, L.F.4
-
26
-
-
41449097556
-
Plasma connective tissue growth factor is a novel potential biomarker of cardiac dysfunction in patients with chronic heart failure
-
Koitabashi N, Arai M, Niwano K, Watanabe A, Endoh M, Suguta M, Yokoyama T, Tada H, Toyama T, Adachi H, Naito S, Oshima S, Nishida T, Kubota S, Takigawa M, and Kurabayashi M. Plasma connective tissue growth factor is a novel potential biomarker of cardiac dysfunction in patients with chronic heart failure. Eur J Heart Fail 10: 373-379, 2008.
-
(2008)
Eur J Heart Fail
, vol.10
, pp. 373-379
-
-
Koitabashi, N.1
Arai, M.2
Niwano, K.3
Watanabe, A.4
Endoh, M.5
Suguta, M.6
Yokoyama, T.7
Tada, H.8
Toyama, T.9
Adachi, H.10
Naito, S.11
Oshima, S.12
Nishida, T.13
Kubota, S.14
Takigawa, M.15
Kurabayashi, M.16
-
27
-
-
79951517589
-
The CCN family: A new class of inflammation modulators?
-
Kular L, Pakradouni J, Kitabgi P, Laurent M, and Martinerie C. The CCN family: a new class of inflammation modulators? Biochimie 93: 377-388, 2011.
-
(2011)
Biochimie
, vol.93
, pp. 377-388
-
-
Kular, L.1
Pakradouni, J.2
Kitabgi, P.3
Laurent, M.4
Martinerie, C.5
-
28
-
-
71549123218
-
Arterial gene transfer of the TGF-beta signalling protein Smad3 induces adaptive remodelling following angioplasty: A role for CTGF
-
Kundi R, Hollenbeck ST, Yamanouchi D, Herman BC, Edlin R, Ryer EJ, Wang C, Tsai S, Liu B, and Kent KC. Arterial gene transfer of the TGF-beta signalling protein Smad3 induces adaptive remodelling following angioplasty: a role for CTGF. Cardiovasc Res 84: 326-335, 2009.
-
(2009)
Cardiovasc Res
, vol.84
, pp. 326-335
-
-
Kundi, R.1
Hollenbeck, S.T.2
Yamanouchi, D.3
Herman, B.C.4
Edlin, R.5
Ryer, E.J.6
Wang, C.7
Tsai, S.8
Liu, B.9
Kent, K.C.10
-
29
-
-
84861062943
-
Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system
-
Lasségue B, San Martín A, and Griendling KK. Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circ Res 110: 1364-1390, 2012.
-
(2012)
Circ Res
, vol.110
, pp. 1364-1390
-
-
Lasségue, B.1
San Martín, A.2
Griendling, K.K.3
-
30
-
-
52049110957
-
Assessment of superoxide production and NADPH oxidase activity by HPLC analysis of dihydroethidium oxidation products
-
Laurindo FR, Fernandes DC, and Santos CX. Assessment of superoxide production and NADPH oxidase activity by HPLC analysis of dihydroethidium oxidation products. Methods Enzymol 441: 237-260, 2008.
-
(2008)
Methods Enzymol
, vol.441
, pp. 237-260
-
-
Laurindo, F.R.1
Fernandes, D.C.2
Santos, C.X.3
-
31
-
-
80055014533
-
CCN2/decorin interactions: A novel approach to combating fibrosis?
-
Leask A. CCN2/decorin interactions: a novel approach to combating fibrosis? J Cell Commun Signal 5: 249-250, 2011.
-
(2011)
J Cell Commun Signal
, vol.5
, pp. 249-250
-
-
Leask, A.1
-
32
-
-
33747873520
-
Role of connective tissue growth factor (CTGF) module 4 in regulating epithelial mesenchymal transition in HK-2 cells
-
Liu BC, Zhang JD, Zhang XL, Wu GQ, and Li MX. Role of connective tissue growth factor (CTGF) module 4 in regulating epithelial mesenchymal transition in HK-2 cells. Clin Chim Acta 373: 144-150, 2006.
-
(2006)
Clin Chim Acta
, vol.373
, pp. 144-150
-
-
Liu, B.C.1
Zhang, J.D.2
Zhang, X.L.3
Wu, G.Q.4
Li, M.X.5
-
33
-
-
77956816714
-
Trimetazidine inhibits pressure overload-induced cardiac fibrosis through NADPH oxidase-ROS-CTGF pathway
-
Liu X, Gai Y, Liu F, Gao W, Zhang Y, Xu M, and Li Z. Trimetazidine inhibits pressure overload-induced cardiac fibrosis through NADPH oxidase-ROS-CTGF pathway. Cardiovasc Res 88: 150-158, 2010.
-
(2010)
Cardiovasc Res
, vol.88
, pp. 150-158
-
-
Liu, X.1
Gai, Y.2
Liu, F.3
Gao, W.4
Zhang, Y.5
Xu, M.6
Li, Z.7
-
34
-
-
33746848638
-
Parthenolide modulates the NF-kappaBmediated inflammatory responses in experimental atherosclerosis
-
López-Franco O, Hernández-Vargas P, Ortiz-Muñoz G, Sanjuán G, Suzuki Y, Ortega L, Blanco J, Egido J, and Gómez-Guerrero C. Parthenolide modulates the NF-kappaBmediated inflammatory responses in experimental atherosclerosis. Arterioscler Thromb Vasc Bio 26: 1864-1870, 2006.
-
(2006)
Arterioscler Thromb Vasc Bio
, vol.26
, pp. 1864-1870
-
-
López-Franco, O.1
Hernández-Vargas, P.2
Ortiz-Muñoz, G.3
Sanjuán, G.4
Suzuki, Y.5
Ortega, L.6
Blanco, J.7
Egido, J.8
Gómez-Guerrero, C.9
-
35
-
-
78650571743
-
Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells
-
Markiewicz M, Nakerakanti SS, Kapanadze B, Ghatnekar A, and Trojanowska M. Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells. Microcirculation 18: 1-11, 2011.
-
(2011)
Microcirculation
, vol.18
, pp. 1-11
-
-
Markiewicz, M.1
Nakerakanti, S.S.2
Kapanadze, B.3
Ghatnekar, A.4
Trojanowska, M.5
-
36
-
-
84870519907
-
Reciprocal relationship between reactive oxygen species and cyclooxygenase-2 and vascular dysfunction in hypertension
-
Martínez-Revelles S, Avendaño MS, García-Redondo AB, Alvarez Y, Aguado A, Pérez-Girón JV, García-Redondo L, Esteban V, Redondo JM, Alonso MJ, Briones AM, and Salaices M. Reciprocal relationship between reactive oxygen species and cyclooxygenase-2 and vascular dysfunction in hypertension. Antioxid Redox Signal 18: 51-65, 2013.
-
(2013)
Antioxid Redox Signal
, vol.18
, pp. 51-65
-
-
Martínez-Revelles, S.1
Avendaño, M.S.2
García-Redondo, A.B.3
Alvarez, Y.4
Aguado, A.5
Pérez-Girón, J.V.6
García-Redondo, L.7
Esteban, V.8
Redondo, J.M.9
Alonso, M.J.10
Briones, A.M.11
Salaices, M.12
-
37
-
-
23244447710
-
Intensive treatment with atorvastatin reduces inflammation in mononuclear cells and human atherosclerotic lesions in one month
-
Martín-Ventura JL, Blanco-Colio LM, Gómez-Hernández A, Muñoz-García B, Vega M, Serrano J, Ortega L, Hernández G, Tuñón J, and Egido J. Intensive treatment with atorvastatin reduces inflammation in mononuclear cells and human atherosclerotic lesions in one month. Stroke 36: 1796-1800, 2005.
-
(2005)
Stroke
, vol.36
, pp. 1796-1800
-
-
Martín-Ventura, J.L.1
Blanco-Colio, L.M.2
Gómez-Hernández, A.3
Muñoz-García, B.4
Vega, M.5
Serrano, J.6
Ortega, L.7
Hernández, G.8
Tuñón, J.9
Egido, J.10
-
38
-
-
75449099482
-
Diabetes and microvascular pathophysiology: Role of epidermal growth factor receptor tyrosine kinase
-
Matrougui K. Diabetes and microvascular pathophysiology: role of epidermal growth factor receptor tyrosine kinase. Diabetes Metab Res Rev 26: 13-16, 2010.
-
(2010)
Diabetes Metab Res Rev
, vol.26
, pp. 13-16
-
-
Matrougui, K.1
-
39
-
-
84874942046
-
CCN2 exerts direct cytoprotective actions in adult cardiac myocytes by activation of the PI3-kinase/Akt/GSK-3b signaling pathway
-
Moe IT, Pham TA, Hagelin EM, Ahmed MS, and Attramadal H. CCN2 exerts direct cytoprotective actions in adult cardiac myocytes by activation of the PI3-kinase/Akt/GSK-3b signaling pathway. J Cell Commun Signal 7: 31-47, 2012.
-
(2012)
J Cell Commun Signal
, vol.7
, pp. 31-47
-
-
Moe, I.T.1
Pham, T.A.2
Hagelin, E.M.3
Ahmed, M.S.4
Attramadal, H.5
-
40
-
-
34247093334
-
Nitric oxide and the vascular endothelium
-
Moncada S and Higgs EA. Nitric oxide and the vascular endothelium. Handb Exp Pharmacol (176 Pt 1): 213-254, 2006.
-
(2006)
Handb Exp Pharmacol
, vol.176
, pp. 213-254
-
-
Moncada, S.1
Higgs, E.A.2
-
41
-
-
78650894319
-
Crosstalk of reactive oxygen species and NF-jB signaling
-
Morgan MJ and Liu ZG. Crosstalk of reactive oxygen species and NF-jB signaling. Cell Res 21: 103-115, 2011.
-
(2011)
Cell Res
, vol.21
, pp. 103-115
-
-
Morgan, M.J.1
Liu, Z.G.2
-
42
-
-
0032794692
-
Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model
-
Mori T, Kawara S, Shinozaki M, Hayashi N, Kakinuma T, Igarashi A, Takigawa M, Nakanishi T, and Takehara K. Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: a mouse fibrosis model. J Cell Physiol 181: 153-159, 1999.
-
(1999)
J Cell Physiol
, vol.181
, pp. 153-159
-
-
Mori, T.1
Kawara, S.2
Shinozaki, M.3
Hayashi, N.4
Kakinuma, T.5
Igarashi, A.6
Takigawa, M.7
Nakanishi, T.8
Takehara, K.9
-
43
-
-
78649357316
-
Is oxidative stress a therapeutic target in cardiovascular disease?
-
Münzel T, Gori T, Bruno RM, and Taddei S. Is oxidative stress a therapeutic target in cardiovascular disease? Eur Heart J 31: 2741-2748, 2010.
-
(2010)
Eur Heart J
, vol.31
, pp. 2741-2748
-
-
Münzel, T.1
Gori, T.2
Bruno, R.M.3
Taddei, S.4
-
44
-
-
16944364613
-
Human connective tissue growth factor is expressed in advanced atherosclerotic lesions
-
Oemar BS, Werner A, Garnier JM, Do DD, Godoy N, Nauck M, März W, Rupp J, Pech M, and Lüscher TF. Human connective tissue growth factor is expressed in advanced atherosclerotic lesions. Circulation 9: 831-839, 1997.
-
(1997)
Circulation
, vol.9
, pp. 831-839
-
-
Oemar, B.S.1
Werner, A.2
Garnier, J.M.3
Do, D.D.4
Godoy, N.5
Nauck, M.6
März, W.7
Rupp, J.8
Pech, M.9
Lüscher, T.F.10
-
45
-
-
69849111913
-
Connective tissue growth factor overexpression in cardiomyocytes promotes cardiac hypertrophy and protection against pressure overload
-
Panek AN, Posch MG, Alenina N, Ghadge SK, Erdmann B, Popova E, Perrot A, Geier C, Dietz R, Morano I, Bader M, and Ozcelik C. Connective tissue growth factor overexpression in cardiomyocytes promotes cardiac hypertrophy and protection against pressure overload. PLoS One 4: e6743, 2009.
-
(2009)
PLoS One
, vol.4
, pp. e6743
-
-
Panek, A.N.1
Posch, M.G.2
Alenina, N.3
Ghadge, S.K.4
Erdmann, B.5
Popova, E.6
Perrot, A.7
Geier, C.8
Dietz, R.9
Morano, I.10
Bader, M.11
Ozcelik, C.12
-
46
-
-
0034805654
-
Hydrogen peroxide is a novel inducer of connective tissue growth factor
-
Park SK, Kim J, Seomun Y, Choi J, Kim DH, Han IO, Lee EH, Chung SK, and Joo CK. Hydrogen peroxide is a novel inducer of connective tissue growth factor. Biochem Biophys Res Commun 284: 966-971, 2001.
-
(2001)
Biochem Biophys Res Commun
, vol.284
, pp. 966-971
-
-
Park, S.K.1
Kim, J.2
Seomun, Y.3
Choi, J.4
Kim, D.H.5
Han, I.O.6
Lee, E.H.7
Chung, S.K.8
Joo, C.K.9
-
47
-
-
0347915577
-
CCN proteins: Multifunctional signaling regulators
-
Perbal B. CCN proteins: multifunctional signaling regulators. Lancet 363: 62-64, 2004.
-
(2004)
Lancet
, vol.363
, pp. 62-64
-
-
Perbal, B.1
-
48
-
-
70849136597
-
Connective tissue growth factor-(CTGF, CCN2) - A marker mediator and therapeutic target for renal fibrosis
-
Phanish MK, Winn SK, and Dockrell ME. Connective tissue growth factor-(CTGF, CCN2)-a marker mediator and therapeutic target for renal fibrosis. Nephron Exp Nephrol 114: e83-e92, 2010.
-
(2010)
Nephron Exp Nephrol
, vol.114
, pp. e83-e92
-
-
Phanish, M.K.1
Winn, S.K.2
Dockrell, M.E.3
-
49
-
-
67650069660
-
Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type i collagen
-
Ponticos M, Holmes AM, Shi-wen X, Leoni P, Khan K, Rajkumar VS, Hoyles RK, Bou-Gharios G, Black CM, Denton CP, Abraham DJ, Leask A, and Lindahl GE. Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen. Arthritis Rheum 60: 2142-2155, 2009.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 2142-2155
-
-
Ponticos, M.1
Holmes, A.M.2
Shi-Wen, X.3
Leoni, P.4
Khan, K.5
Rajkumar, V.S.6
Hoyles, R.K.7
Bou-Gharios, G.8
Black, C.M.9
Denton, C.P.10
Abraham, D.J.11
Leask, A.12
Lindahl, G.E.13
-
50
-
-
84875367781
-
Connective tissue growth factor (CCN2) in blood vessels
-
Ponticos M. Connective tissue growth factor (CCN2) in blood vessels. Vascul Pharmacol 58: 189-193, 2013.
-
(2013)
Vascul Pharmacol
, vol.58
, pp. 189-193
-
-
Ponticos, M.1
-
51
-
-
84885361617
-
Connective tissue growth factor is a new ligand of epidermal growth factor receptor
-
Rayego-Mateos S, Rodrigues-Díez R, Morgado-Pascual JL, Rodrigues Díez RR, Mas S, Lavoz C, Alique M, Pato J, Keri G, Ortiz A, Egido J, and Ruiz-Ortega M. Connective tissue growth factor is a new ligand of epidermal growth factor receptor. J Mol Cell Biol 5: 323-335, 2013.
-
(2013)
J Mol Cell Biol
, vol.5
, pp. 323-335
-
-
Rayego-Mateos, S.1
Rodrigues-Díez, R.2
Morgado-Pascual, J.L.3
Rodrigues Díez, R.R.4
Mas, S.5
Lavoz, C.6
Alique, M.7
Pato, J.8
Keri, G.9
Ortiz, A.10
Egido, J.11
Ruiz-Ortega, M.12
-
52
-
-
84879646795
-
The C-terminal module IV of connective tissue growth factor is a novel immune modulator of the Th17 response
-
Rodrigues-Díez R, Rodrigues-Díez RR, Rayego-Mateos S, Suarez-Alvarez B, Lavoz C, Stark Aroeira L, Sánchez-López E, Orejudo M, Alique M, Lopez-Larrea C, Ortiz A, Egido J, and Ruiz-Ortega M. The C-terminal module IV of connective tissue growth factor is a novel immune modulator of the Th17 response. Lab Invest 93: 812-824, 2013.
-
(2013)
Lab Invest
, vol.93
, pp. 812-824
-
-
Rodrigues-Díez, R.1
Rodrigues-Díez, R.R.2
Rayego-Mateos, S.3
Suarez-Alvarez, B.4
Lavoz, C.5
Stark Aroeira, L.6
Sánchez-López, E.7
Orejudo, M.8
Alique, M.9
Lopez-Larrea, C.10
Ortiz, A.11
Egido, J.12
Ruiz-Ortega, M.13
-
53
-
-
22744459775
-
Endothelin-1, via ETA receptor and independently of transforming growth factor-beta, increases the connective tissue growth factor in vascular smooth muscle cells
-
Rodriguez-Vita J, Ruiz-Ortega M, Rupérez M, Esteban V, Sanchez-López E, Plaza JJ, and Egido J. Endothelin-1, via ETA receptor and independently of transforming growth factor-beta, increases the connective tissue growth factor in vascular smooth muscle cells. Circ Res 97: 125-134, 2005.
-
(2005)
Circ Res
, vol.97
, pp. 125-134
-
-
Rodriguez-Vita, J.1
Ruiz-Ortega, M.2
Rupérez, M.3
Esteban, V.4
Sanchez-López, E.5
Plaza, J.J.6
Egido, J.7
-
54
-
-
24144483086
-
Angiotensin II and reactive oxygens pecies
-
Ruiz-Ortega M and Ortiz A. Angiotensin II and reactive oxygens pecies. Antioxid Redox Signal 7: 1258-1260, 2005.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 1258-1260
-
-
Ruiz-Ortega, M.1
Ortiz, A.2
-
55
-
-
33646792585
-
Renal and vascular hypertension-induced inflammation: Role of angiotensin II
-
Ruiz-Ortega M, Esteban V, Rupérez M, Sánchez-López E, Rodríguez-Vita J, Carvajal G, and Egido J. Renal and vascular hypertension-induced inflammation: role of angiotensin II. Curr Opin Nephrol Hypertens 15: 159-166, 2006.
-
(2006)
Curr Opin Nephrol Hypertens
, vol.15
, pp. 159-166
-
-
Ruiz-Ortega, M.1
Esteban, V.2
Rupérez, M.3
Sánchez-López, E.4
Rodríguez-Vita, J.5
Carvajal, G.6
Egido, J.7
-
56
-
-
34047156556
-
TGF-beta signaling in vascular fibrosis
-
Ruiz-Ortega M, Rodríguez-Vita J, Sanchez-Lopez E, Carvajal G, and Egido J. TGF-beta signaling in vascular fibrosis. Cardiovasc Res 74: 196-206, 2007.
-
(2007)
Cardiovasc Res
, vol.74
, pp. 196-206
-
-
Ruiz-Ortega, M.1
Rodríguez-Vita, J.2
Sanchez-Lopez, E.3
Carvajal, G.4
Egido, J.5
-
57
-
-
18744430508
-
Connective tissue growth factor is a mediator of angiotensin II-induced fibrosis
-
Rupérez M, Lorenzo O, Blanco-Colio LM, Esteban V, Egido J, and Ruiz-Ortega M. Connective tissue growth factor is a mediator of angiotensin II-induced fibrosis. Circulation 108: 1499-1505, 2003.
-
(2003)
Circulation
, vol.108
, pp. 1499-1505
-
-
Rupérez, M.1
Lorenzo, O.2
Blanco-Colio, L.M.3
Esteban, V.4
Egido, J.5
Ruiz-Ortega, M.6
-
58
-
-
38349078516
-
Inhibitory effect of interleukin-1 on angiotensin II-induced connective tissue growth factor and type IV collagen production in cultured mesangial cells
-
Sánchez-López E, Rodriguez-Vita J, Cartier C, Rupérez M, Esteban V, Carvajal G, Rodrígues-Díez R, Plaza JJ, Egido J, and Ruiz-Ortega M. Inhibitory effect of interleukin-1 on angiotensin II-induced connective tissue growth factor and type IV collagen production in cultured mesangial cells. Am J Physiol Renal Physiol 294: F149-F160, 2008.
-
(2008)
Am J Physiol Renal Physiol
, vol.294
, pp. F149-F160
-
-
Sánchez-López, E.1
Rodriguez-Vita, J.2
Cartier, C.3
Rupérez, M.4
Esteban, V.5
Carvajal, G.6
Rodrígues-Díez, R.7
Plaza, J.J.8
Egido, J.9
Ruiz-Ortega, M.10
-
59
-
-
67649674622
-
CTGF promotes inflammatory cell infiltration of the renal interstitium by activating NF-kappaB
-
Sánchez-López E, Rayego S, Rodrigues-Díez R, Rodriguez JS, Rodrigues-Díez R, Rodríguez-Vita J, Carvajal G, Aroeira LS, Selgas R, Mezzano SA, Ortiz A, Egido J, and Ruiz-Ortega M. CTGF promotes inflammatory cell infiltration of the renal interstitium by activating NF-kappaB. J Am Soc Nephrol 20: 1513-1526, 2009.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 1513-1526
-
-
Sánchez-López, E.1
Rayego, S.2
Rodrigues-Díez, R.3
Rodriguez, J.S.4
Rodrigues-Díez, R.5
Rodríguez-Vita, J.6
Carvajal, G.7
Aroeira, L.S.8
Selgas, R.9
Mezzano, S.A.10
Ortiz, A.11
Egido, J.12
Ruiz-Ortega, M.13
-
60
-
-
77955644910
-
NFkappaB in renal inflammation
-
Sanz AB, Sanchez-Niño MD, Ramos AM, Moreno JA, Santamaria B, Ruiz-Ortega M, Egido J, and Ortiz A. NFkappaB in renal inflammation. J Am Soc Nephrol 21: 1254-1262, 2010.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1254-1262
-
-
Sanz, A.B.1
Sanchez-Niño, M.D.2
Ramos, A.M.3
Moreno, J.A.4
Santamaria, B.5
Ruiz-Ortega, M.6
Egido, J.7
Ortiz, A.8
-
61
-
-
34247136835
-
Vascular inflammation in hypertension and diabetes: Molecular mechanisms and therapeutic interventions
-
Savoia C and Schiffrin EL. Vascular inflammation in hypertension and diabetes: molecular mechanisms and therapeutic interventions. Clin Sci (Lond) 112: 375-384, 2007.
-
(2007)
Clin Sci (Lond)
, vol.112
, pp. 375-384
-
-
Savoia, C.1
Schiffrin, E.L.2
-
62
-
-
84894062402
-
Role of epidermal growth factor receptor in vascular structure and function
-
Schreier B, Gekle M, and Grossmann C. Role of epidermal growth factor receptor in vascular structure and function. Curr Opin Nephrol Hypertens 23: 113-121, 2014.
-
(2014)
Curr Opin Nephrol Hypertens
, vol.23
, pp. 113-121
-
-
Schreier, B.1
Gekle, M.2
Grossmann, C.3
-
63
-
-
0037032024
-
Angiotensin II stimulation of NAD(P)H oxidase activity: Upstream mediators
-
Seshiah PN, Weber DS, Rocic P, Valppu L, Taniyama Y, and Griendling KK. Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators. Circ Res 91: 406-413, 2002.
-
(2002)
Circ Res
, vol.91
, pp. 406-413
-
-
Seshiah, P.N.1
Weber, D.S.2
Rocic, P.3
Valppu, L.4
Taniyama, Y.5
Griendling, K.K.6
-
64
-
-
80054704273
-
NADPH oxidases in cardiovascular disease: Insights from in vivo models and clinical studies
-
Sirker A, Zhang M, and Shah AM. NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies. Basic Res Cardiol 106: 735-747, 2011.
-
(2011)
Basic Res Cardiol
, vol.106
, pp. 735-747
-
-
Sirker, A.1
Zhang, M.2
Shah, A.M.3
-
65
-
-
84857132548
-
Diabetes mellitus and vascular endothelial dysfunction: Current perspectives
-
Tousoulis D, Kampoli AM, and Stefanadis C. Diabetes mellitus and vascular endothelial dysfunction: current perspectives. Curr Vasc Pharmacol 10: 19-32, 2012.
-
(2012)
Curr Vasc Pharmacol
, vol.10
, pp. 19-32
-
-
Tousoulis, D.1
Kampoli, A.M.2
Stefanadis, C.3
-
66
-
-
79953172586
-
NOX1 isoforms and reactive oxygen species in vascular health
-
Touyz RM, Briones AM, Sedeek M, Burger D, and Montezano AC. NOX1 isoforms and reactive oxygen species in vascular health. Mol Interv 11: 27-35, 2011.
-
(2011)
Mol Interv
, vol.11
, pp. 27-35
-
-
Touyz, R.M.1
Briones, A.M.2
Sedeek, M.3
Burger, D.4
Montezano, A.C.5
-
67
-
-
14044249491
-
Expression and localization of NOX2 and NOX4 in primary human endothelial cells
-
Van Buul JD, Fernandez-Borja M, Anthony EC, and Hordijk PL. Expression and localization of NOX2 and NOX4 in primary human endothelial cells. Antioxid Redox Signal 7: 308-317, 2005.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 308-317
-
-
Van Buul, J.D.1
Fernandez-Borja, M.2
Anthony, E.C.3
Hordijk, P.L.4
-
68
-
-
77954036224
-
Role of nuclear factor kappaB in cardiovascular health and disease
-
Van der Heiden K, Cuhlmann S, Luong le A, Zakkar M, and Evans PC. Role of nuclear factor kappaB in cardiovascular health and disease. Clin Sci (Lond) 118: 593-605, 2010.
-
(2010)
Clin Sci (Lond)
, vol.118
, pp. 593-605
-
-
Van Der Heiden, K.1
Cuhlmann, S.2
Luong Le, A.3
Zakkar, M.4
Evans, P.C.5
-
69
-
-
82255171911
-
Oxidative stress and vascular damage in hypertension: Role of angiotensin II
-
Virdis A, Duranti E, and Taddei S. Oxidative stress and vascular damage in hypertension: role of angiotensin II. Int J Hypertens 916310, 2011. DOI: 10.4061/2011/916310.
-
(2011)
Int J Hypertens
, pp. 916310
-
-
Virdis, A.1
Duranti, E.2
Taddei, S.3
-
70
-
-
77249106466
-
Regulation of pro-inflammatory and pro-fibrotic factors by CCN2/CTGF in H9c2 cardiomyocytes
-
Wang X, McLennan SV, Allen TJ, and Twigg SM. Regulation of pro-inflammatory and pro-fibrotic factors by CCN2/CTGF in H9c2 cardiomyocytes. J Cell Commun Signal 4: 15-23, 2010.
-
(2010)
J Cell Commun Signal
, vol.4
, pp. 15-23
-
-
Wang, X.1
McLennan, S.V.2
Allen, T.J.3
Twigg, S.M.4
-
71
-
-
79952445768
-
Knockdown of connective tissue growth factor by plasmidbased short hairpin RNA prevented pulmonary vascular remodeling in cigarette smoke-exposed rats
-
Wang R, Xu YJ, Liu XS, Zeng DX, and Xiang M. Knockdown of connective tissue growth factor by plasmidbased short hairpin RNA prevented pulmonary vascular remodeling in cigarette smoke-exposed rats. Arch Biochem Biophys 508: 93-100, 2011.
-
(2011)
Arch Biochem Biophys
, vol.508
, pp. 93-100
-
-
Wang, R.1
Xu, Y.J.2
Liu, X.S.3
Zeng, D.X.4
Xiang, M.5
-
72
-
-
59849114489
-
Signal transduction involved in CTGF-induced production of chemokines in mesangial cells
-
Wu S-H, Lu C, Dong L, and Chen Z-Q. Signal transduction involved in CTGF-induced production of chemokines in mesangial cells. Growth Factors 26: 192-200, 2008.
-
(2008)
Growth Factors
, vol.26
, pp. 192-200
-
-
Wu, S.-H.1
Lu, C.2
Dong, L.3
Chen, Z.-Q.4
|