Diabetes and microvascular pathophysiology: Role of epidermal growth factor receptor tyrosine kinase

Diabetes/Metabolism Research and Reviews

Volumn 26, Issue 1, 2010, Pages 13-16

  Matrougui, Khalid ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

EGFR tyrosine kinase; Microvessels; Type 2 diabetes

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; GELATINASE A; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE C;

CORONARY ARTERY; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; INSULIN DEPENDENT DIABETES MELLITUS; INTESTINE PRESSURE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVIEW; STREPTOZOCIN DIABETES; WESTERN BLOTTING;

ANIMALS; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; DISEASE MODELS, ANIMAL; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICROCIRCULATION; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 75449099482     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.1050     Document Type: Review

References (19)

1. Morrish NJ, Wang SL, Stevens LK, Fuller JH, Keen H. Mortality and causes of death in the WHO Multinational Study of Vascular Disease in Diabetes. Diabetologia 2001; 44(Suppl. 2): S14-S21.
2. Mahmud A, Feely J. Arterial stiffness and the renin- angiotensinaldosterone system. J Renin Angiotensin Aldosterone Syst 2004; 5: 102-108.
3. Kassab GS, Molloi S. Cross-sectional area and volume compliance of porcine left coronary arteries. Am J Physiol Heart Circ Physiol 2001; 281: H623-H628.
4. Hoffman JI, Spaan JA. Pressure-flow relations in coronary circulation. Physiol Rev 1990; 70: 331-390.
5. Zhai P, Galeotti J, Liu J, et al. An angiotensin II type 1 receptor mutant lacking epidermal growth factor receptor transactivation does not induce angiotensin II-mediated cardiac hypertrophy. Circ Res 2006; 99: 528-536.
6. Lucchesi PA, Sabri A, Belmadani S, Matrougui K. Involvement of metalloproteinases 2/9 in epidermal growth factor receptor transactivation in pressure-induced myogenic tone in mouse mesenteric resistance arteries. Circulation 2004; 110: 3587-3593.
7. Shida D, Kitayama J, Mori K, Watanabe T, Nagawa H. Transactivation of epidermal growth factor receptor is involved in leptin-induced activation of janus-activated kinase 2 and extracellular signal-regulated kinase 1/2 in human gastric cancer cells. Cancer Res 2005; 65: 9159-9163.
8. Schneider MR, Wolf E. The epidermal growth factor receptor ligands at a glance. J Cell Physiol 2009; 218: 460-466.
9. Belmadani S, Matrougui K, Kolz C, et al. Amplification of coronary arteriogenic capacity of multipotent stromal cells by epidermal growth factor. Arterioscler Thromb Vasc Biol 2009; 29: 802-808.
10. Belmadani S, Palen DI, Gonzalez-Villalobos RA, Boulares HA, Matrougui K. Elevated epidermal growth factor receptor phosphorylation induces resistance artery dysfunction in diabetic db/db mice. Diabetes 2008; 57: 1629-1637.
11. Palen DI, Belmadani S, Lucchesi PA, Matrougui K. Role of SHP-1, Kv.1.2, and cGMP in nitric oxide-induced ERK1/2 MAP kinase dephosphorylation in rat vascular smooth muscle cells. Cardiovasc Res 2005; 68: 268-277.
12. 2+ channels and protein kinase C. Cardiovasc Res 1999; 43: 1018-1028.
13. Lagaud GJ, Masih-Khan E, Kai S, van Breemen C, Dube GP. Influence of type II diabetes on arterial tone and endothelial function in murine mesenteric resistance arteries. J Vasc Res 2001; 38: 578-589.
14. Bagi Z, Koller A, Kaley G. Superoxide-NO interaction decreases flow- and agonist-induced dilations of coronary arterioles in Type 2 diabetes mellitus. Am J Physiol Heart Circ Physiol 2003; 285: H1404-H1410.
15. Schofield I, Malik R, Izzard A, Austin C, Heagerty A. Vascular structural and functional changes in type 2 diabetes mellitus: evidence for the roles of abnormal myogenic responsiveness and dyslipidemia. Circulation 2002; 106: 3037-3043.
16. Belmadani S, Palen DI, Gonzalez-Villalobos RA, Boulares HA, Matrougui K. Elevated epidermal growth factor receptor phosphorylation induces resistance artery dysfunction in diabetic db/db mice. Diabetes 2008; 57: 1629-1637.
17. Konishi A, Berk BC. Epidermal growth factor receptor transactivation is regulated by glucose in vascular smoothmuscle cells. J Biol Chem 2003; 278: 35049-35056.
18. Palen DI, Matrougui K. Role of elevated EGFR phosphorylation in the induction of structural remodelling and altered mechanical properties of resistance artery from type 2 diabetic mice. Diabetes Metab Res Rev 2008; 24: 651-656.
19. Benter IF, Benboubetra M, Hollins AJ, Yousif MH, Canatan H, Akhtar S. Early inhibition of EGFR signaling prevents diabetes-induced up-regulation of multiple gene pathways in the mesenteric vasculature. Vascul Pharmacol 2009; 51: 236-245.