Oxidative stress modulates vascular smooth muscle cell phenotype via CTGF in thoracic aortic aneurysm

Cardiovascular Research

Volumn 100, Issue 2, 2013, Pages 316-324

  Branchetti, Emanuela ^a   Poggio, Paolo ^a,b   Sainger, Rachana ^a   Shang, Eric ^c   Grau, Juan B ^a,d   Jackson, Benjamin M ^c   Lai, Eric K ^a   Parmacek, Michael S ^c   Gorman, Robert C ^a   Gorman, Joseph H ^a   Bavaria, Joseph E ^a   Ferrari, Giovanni ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d VALLEY HOSPITAL   (United States)

Author keywords

CTGF; ROS; Thoracic aortic aneurysm; VSMC phenotype

Indexed keywords

ANGIOTENSIN II; CONNECTIVE TISSUE GROWTH FACTOR; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL WALL THICKENING; ARTICLE; ASCENDING AORTA; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE ASSOCIATION; EX VIVO STUDY; FINITE ELEMENT ANALYSIS; HEART HEMODYNAMICS; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; THORACIC AORTA ANEURYSM; TISSUE DEGENERATION; VASCULAR SMOOTH MUSCLE; VASCULAR SMOOTH MUSCLE CELL; WALL STRESS;

CTGF; ROS; THORACIC AORTIC ANEURYSM; VSMC PHENOTYPE;

ANGIOTENSIN II; ANIMALS; AORTIC ANEURYSM, THORACIC; CONNECTIVE TISSUE GROWTH FACTOR; ETS-DOMAIN PROTEIN ELK-1; FINITE ELEMENT ANALYSIS; HUMANS; MICE; MICE, INBRED C57BL; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OXIDATIVE STRESS; PHENOTYPE; REACTIVE OXYGEN SPECIES; SERUM RESPONSE FACTOR; VIMENTIN;

EID: 84886077894     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvt205     Document Type: Article

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