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Volumn 171, Issue 24, 2014, Pages 5507-5523

Movers and shakers: Cell cytoskeleton in cancer metastasis

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ACTIVITY REGULATED CYTOSKELETON ASSOCIATED PROTEIN; COFILIN; MYOSIN ADENOSINE TRIPHOSPHATASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; TROPOMYOSIN;

EID: 84918831129     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12704     Document Type: Review
Times cited : (435)

References (155)
  • 3
    • 84892494418 scopus 로고    scopus 로고
    • Microtubules and actin crosstalk in cell migration and division
    • Akhshi TK, Wernike D, Piekny A, (2014). Microtubules and actin crosstalk in cell migration and division. Cytoskeleton (Hoboken) 71: 1-23.
    • (2014) Cytoskeleton (Hoboken) , vol.71 , pp. 1-23
    • Akhshi, T.K.1    Wernike, D.2    Piekny, A.3
  • 5
    • 33846051928 scopus 로고    scopus 로고
    • Mechanisms of invasion and metastasis in human neuroblastoma
    • Ara T, DeClerck YA, (2006). Mechanisms of invasion and metastasis in human neuroblastoma. Cancer Metastasis Rev 25: 645-657.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 645-657
    • Ara, T.1    Declerck, Y.A.2
  • 6
    • 62849099763 scopus 로고    scopus 로고
    • Tropomyosin isoform expression regulates the transition of adhesions to determine cell speed and direction
    • Bach CT, Creed S, Zhong J, Mahmassani M, Schevzov G, Stehn J, et al. (2009). Tropomyosin isoform expression regulates the transition of adhesions to determine cell speed and direction. Mol Cell Biol 29: 1506-1514.
    • (2009) Mol Cell Biol , vol.29 , pp. 1506-1514
    • Bach, C.T.1    Creed, S.2    Zhong, J.3    Mahmassani, M.4    Schevzov, G.5    Stehn, J.6
  • 7
    • 77953564050 scopus 로고    scopus 로고
    • Tropomyosin isoform modulation of focal adhesion structure and cell migration
    • Bach CT, Schevzov G, Bryce NS, Gunning PW, O'Neill GM, (2010). Tropomyosin isoform modulation of focal adhesion structure and cell migration. Cell Adh Migr 4: 226-234.
    • (2010) Cell Adh Migr , vol.4 , pp. 226-234
    • Bach, C.T.1    Schevzov, G.2    Bryce, N.S.3    Gunning, P.W.4    O'Neill, G.M.5
  • 8
    • 33646376457 scopus 로고    scopus 로고
    • LIM kinase 1 increases tumor metastasis of human breast cancer cells via regulation of the urokinase-type plasminogen activator system
    • Bagheri-Yarmand R, Mazumdar A, Sahin AA, Kumar R, (2006). LIM kinase 1 increases tumor metastasis of human breast cancer cells via regulation of the urokinase-type plasminogen activator system. Int J Cancer 118: 2703-2710.
    • (2006) Int J Cancer , vol.118 , pp. 2703-2710
    • Bagheri-Yarmand, R.1    Mazumdar, A.2    Sahin, A.A.3    Kumar, R.4
  • 10
    • 80054698475 scopus 로고    scopus 로고
    • Stathmin: A protein with many tasks. New biomarker and potential target in cancer
    • Belletti B, Baldassarre G, (2011). Stathmin: a protein with many tasks. New biomarker and potential target in cancer. Expert Opin Ther Targets 15: 1249-1266.
    • (2011) Expert Opin Ther Targets , vol.15 , pp. 1249-1266
    • Belletti, B.1    Baldassarre, G.2
  • 11
    • 34249315804 scopus 로고    scopus 로고
    • Lim kinases, regulators of actin dynamics
    • Bernard O, (2007). Lim kinases, regulators of actin dynamics. Int J Biochem Cell Biol 39: 1071-1076.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 1071-1076
    • Bernard, O.1
  • 12
    • 30544436402 scopus 로고    scopus 로고
    • Resensitization of breast cancer cells to anoikis by tropomyosin-1: Role of Rho kinase-dependent cytoskeleton and adhesion
    • Bharadwaj S, Thanawala R, Bon G, Falcioni R, Prasad GL, (2005). Resensitization of breast cancer cells to anoikis by tropomyosin-1: role of Rho kinase-dependent cytoskeleton and adhesion. Oncogene 24: 8291-8303.
    • (2005) Oncogene , vol.24 , pp. 8291-8303
    • Bharadwaj, S.1    Thanawala, R.2    Bon, G.3    Falcioni, R.4    Prasad, G.L.5
  • 13
  • 14
    • 84894064647 scopus 로고    scopus 로고
    • RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model
    • Byrne FA, Yang Y, Phillips AA, Hansford LM, Fletcher JI, Ormandy CJ, et al. (2014). RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model. Oncogene 33: 882-890.
    • (2014) Oncogene , vol.33 , pp. 882-890
    • Byrne, F.A.1    Yang, Y.2    Phillips, A.A.3    Hansford, L.M.4    Fletcher, J.I.5    Ormandy, C.J.6
  • 15
    • 77954954740 scopus 로고    scopus 로고
    • Expression of cortactin correlates with a poor prognosis in patients with stages II-III colorectal adenocarcinoma
    • Cai JH, Zhao R, Zhu JW, Jin XL, Wan FJ, Liu K, et al. (2010). Expression of cortactin correlates with a poor prognosis in patients with stages II-III colorectal adenocarcinoma. J Gastrointest Surg 14: 1248-1257.
    • (2010) J Gastrointest Surg , vol.14 , pp. 1248-1257
    • Cai, J.H.1    Zhao, R.2    Zhu, J.W.3    Jin, X.L.4    Wan, F.J.5    Liu, K.6
  • 16
    • 34249697100 scopus 로고    scopus 로고
    • Muscle intermediate filaments and their links to membranes and membranous organelles
    • Capetanaki Y, Bloch RJ, Kouloumenta A, Mavroidis M, Psarras S, (2007). Muscle intermediate filaments and their links to membranes and membranous organelles. Exp Cell Res 313: 2063-2076.
    • (2007) Exp Cell Res , vol.313 , pp. 2063-2076
    • Capetanaki, Y.1    Bloch, R.J.2    Kouloumenta, A.3    Mavroidis, M.4    Psarras, S.5
  • 17
    • 3543113113 scopus 로고    scopus 로고
    • Intermediate filaments mediate cytoskeletal crosstalk
    • Chang L, Goldman RD, (2004). Intermediate filaments mediate cytoskeletal crosstalk. Nat Rev Mol Cell Biol 5: 601-613.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 601-613
    • Chang, L.1    Goldman, R.D.2
  • 18
    • 50149095564 scopus 로고    scopus 로고
    • Blebs lead the way: How to migrate without lamellipodia
    • Charras G, Paluch E, (2008). Blebs lead the way: how to migrate without lamellipodia. Nat Rev Mol Cell Biol 9: 730-736.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 730-736
    • Charras, G.1    Paluch, E.2
  • 19
    • 34247537076 scopus 로고    scopus 로고
    • Hypoxia and metastasis
    • Chaudary N, Hill RP, (2007). Hypoxia and metastasis. Clin Cancer Res 13: 1947-1949.
    • (2007) Clin Cancer Res , vol.13 , pp. 1947-1949
    • Chaudary, N.1    Hill, R.P.2
  • 20
    • 4644271628 scopus 로고    scopus 로고
    • Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma
    • Chuma M, Sakamoto M, Yasuda J, Fujii G, Nakanishi K, Tsuchiya A, et al. (2004). Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma. J Hepatol 41: 629-636.
    • (2004) J Hepatol , vol.41 , pp. 629-636
    • Chuma, M.1    Sakamoto, M.2    Yasuda, J.3    Fujii, G.4    Nakanishi, K.5    Tsuchiya, A.6
  • 21
    • 0038751716 scopus 로고    scopus 로고
    • Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3beta (GSK-3beta) in vitro
    • Cordes N, van Beuningen D, (2003). Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3beta (GSK-3beta) in vitro. Br J Cancer 88: 1470-1479.
    • (2003) Br J Cancer , vol.88 , pp. 1470-1479
    • Cordes, N.1    Van Beuningen, D.2
  • 22
    • 84862301244 scopus 로고    scopus 로고
    • Advancements in the treatment of metastatic breast cancer (MBC): The role of ixabepilone
    • Cristofanilli M, (2012). Advancements in the treatment of metastatic breast cancer (MBC): the role of ixabepilone. J Oncol 2012: 703858.
    • (2012) J Oncol , vol.2012 , pp. 703858
    • Cristofanilli, M.1
  • 23
    • 33645048173 scopus 로고    scopus 로고
    • The cytoskeleton regulatory protein hMena (ENAH) is overexpressed in human benign breast lesions with high risk of transformation and human epidermal growth factor receptor-2-positive/hormonal receptor-negative tumors
    • Di Modugno F, Mottolese M, Di Benedetto A, Conidi A, Novelli F, Perracchio L, et al. (2006). The cytoskeleton regulatory protein hMena (ENAH) is overexpressed in human benign breast lesions with high risk of transformation and human epidermal growth factor receptor-2-positive/hormonal receptor-negative tumors. Clin Cancer Res 12: 1470-1478.
    • (2006) Clin Cancer Res , vol.12 , pp. 1470-1478
    • Di Modugno, F.1    Mottolese, M.2    Di Benedetto, A.3    Conidi, A.4    Novelli, F.5    Perracchio, L.6
  • 24
    • 67650481175 scopus 로고    scopus 로고
    • Oncosome formation in prostate cancer: Association with a region of frequent chromosomal deletion in metastatic disease
    • Di Vizio D, Kim J, Hager MH, Morello M, Yang W, Lafargue CJ, et al. (2009). Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease. Cancer Res 69: 5601-5609.
    • (2009) Cancer Res , vol.69 , pp. 5601-5609
    • Di Vizio, D.1    Kim, J.2    Hager, M.H.3    Morello, M.4    Yang, W.5    Lafargue, C.J.6
  • 25
    • 33846012211 scopus 로고    scopus 로고
    • Proteomic analysis of isolated membrane fractions from superinvasive cancer cells
    • Dowling P, Meleady P, Dowd A, Henry M, Glynn S, Clynes M, (2007). Proteomic analysis of isolated membrane fractions from superinvasive cancer cells. Biochim Biophys Acta 1774: 93-101.
    • (2007) Biochim Biophys Acta , vol.1774 , pp. 93-101
    • Dowling, P.1    Meleady, P.2    Dowd, A.3    Henry, M.4    Glynn, S.5    Clynes, M.6
  • 26
    • 77957374075 scopus 로고    scopus 로고
    • Microtubule-binding agents: A dynamic field of cancer therapeutics
    • Dumontet C, Jordan MA, (2010). Microtubule-binding agents: a dynamic field of cancer therapeutics. Nat Rev Drug Discov 9: 790-803.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 790-803
    • Dumontet, C.1    Jordan, M.A.2
  • 27
    • 0033194037 scopus 로고    scopus 로고
    • Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics
    • Edwards DC, Sanders LC, Bokoch GM, Gill GN, (1999). Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics. Nat Cell Biol 1: 253-259.
    • (1999) Nat Cell Biol , vol.1 , pp. 253-259
    • Edwards, D.C.1    Sanders, L.C.2    Bokoch, G.M.3    Gill, G.N.4
  • 28
    • 84867294552 scopus 로고    scopus 로고
    • Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells
    • Eitaki M, Yamamori T, Meike S, Yasui H, Inanami O, (2012). Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells. BMC Cancer 12: 469.
    • (2012) BMC Cancer , vol.12 , pp. 469
    • Eitaki, M.1    Yamamori, T.2    Meike, S.3    Yasui, H.4    Inanami, O.5
  • 29
    • 0035943401 scopus 로고    scopus 로고
    • Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta
    • Etienne-Manneville S, Hall A, (2001). Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta. Cell 106: 489-498.
    • (2001) Cell , vol.106 , pp. 489-498
    • Etienne-Manneville, S.1    Hall, A.2
  • 30
    • 45349096499 scopus 로고    scopus 로고
    • Cell motility through plasma membrane blebbing
    • Fackler OT, Grosse R, (2008). Cell motility through plasma membrane blebbing. J Cell Biol 181: 879-884.
    • (2008) J Cell Biol , vol.181 , pp. 879-884
    • Fackler, O.T.1    Grosse, R.2
  • 31
    • 77954563464 scopus 로고    scopus 로고
    • Hypoxia, inflammation, and the tumor microenvironment in metastatic disease
    • Finger EC, Giaccia AJ, (2010). Hypoxia, inflammation, and the tumor microenvironment in metastatic disease. Cancer Metastasis Rev 29: 285-293.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 285-293
    • Finger, E.C.1    Giaccia, A.J.2
  • 33
    • 57149120786 scopus 로고    scopus 로고
    • Tubulin-targeted drug action: Functional significance of class ii and class IVb beta-tubulin in vinca alkaloid sensitivity
    • Gan PP, Kavallaris M, (2008). Tubulin-targeted drug action: functional significance of class ii and class IVb beta-tubulin in vinca alkaloid sensitivity. Cancer Res 68: 9817-9824.
    • (2008) Cancer Res , vol.68 , pp. 9817-9824
    • Gan, P.P.1    Kavallaris, M.2
  • 34
    • 35148854099 scopus 로고    scopus 로고
    • Class III beta-tubulin mediates sensitivity to chemotherapeutic drugs in non small cell lung cancer
    • Gan PP, Pasquier E, Kavallaris M, (2007). Class III beta-tubulin mediates sensitivity to chemotherapeutic drugs in non small cell lung cancer. Cancer Res 67: 9356-9363.
    • (2007) Cancer Res , vol.67 , pp. 9356-9363
    • Gan, P.P.1    Pasquier, E.2    Kavallaris, M.3
  • 37
    • 0030006606 scopus 로고    scopus 로고
    • Desmosomes and hemidesmosomes: Structure and function of molecular components
    • Green KJ, Jones JC, (1996). Desmosomes and hemidesmosomes: structure and function of molecular components. FASEB J 10: 871-881.
    • (1996) FASEB J , vol.10 , pp. 871-881
    • Green, K.J.1    Jones, J.C.2
  • 38
    • 0033793141 scopus 로고    scopus 로고
    • Growth and migration markers of rat C6 glioma cells identified by serial analysis of gene expression
    • Gunnersen JM, Spirkoska V, Smith PE, Danks RA, Tan SS, (2000). Growth and migration markers of rat C6 glioma cells identified by serial analysis of gene expression. Glia 32: 146-154.
    • (2000) Glia , vol.32 , pp. 146-154
    • Gunnersen, J.M.1    Spirkoska, V.2    Smith, P.E.3    Danks, R.A.4    Tan, S.S.5
  • 39
    • 38349059960 scopus 로고    scopus 로고
    • Tropomyosin-based regulation of the actin cytoskeleton in time and space
    • Gunning P, O'Neill G, Hardeman E, (2008). Tropomyosin-based regulation of the actin cytoskeleton in time and space. Physiol Rev 88: 1-35.
    • (2008) Physiol Rev , vol.88 , pp. 1-35
    • Gunning, P.1    O'Neill, G.2    Hardeman, E.3
  • 40
    • 33745245989 scopus 로고    scopus 로고
    • Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration
    • Gupton SL, Waterman-Storer CM, (2006). Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration. Cell 125: 1361-1374.
    • (2006) Cell , vol.125 , pp. 1361-1374
    • Gupton, S.L.1    Waterman-Storer, C.M.2
  • 41
    • 0025223706 scopus 로고
    • N-myc gene amplification in neuroblastoma is associated with altered phosphorylation of a proliferation related polypeptide (Op18)
    • Hailat N, Strahler J, Melhem R, Zhu XX, Brodeur G, Seeger RC, et al. (1990). N-myc gene amplification in neuroblastoma is associated with altered phosphorylation of a proliferation related polypeptide (Op18). Oncogene 5: 1615-1618.
    • (1990) Oncogene , vol.5 , pp. 1615-1618
    • Hailat, N.1    Strahler, J.2    Melhem, R.3    Zhu, X.X.4    Brodeur, G.5    Seeger, R.C.6
  • 42
    • 84870209800 scopus 로고    scopus 로고
    • Rho family GTPases
    • Hall A, (2012). Rho family GTPases. Biochem Soc Trans 40: 1378-1382.
    • (2012) Biochem Soc Trans , vol.40 , pp. 1378-1382
    • Hall, A.1
  • 43
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA, (2011). Hallmarks of cancer: the next generation. Cell 144: 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 44
    • 12144286892 scopus 로고    scopus 로고
    • Differential gene and protein expression in primary breast malignancies and their lymph node metastases as revealed by combined cDNA microarray and tissue microarray analysis
    • Hao X, Sun B, Hu L, Lahdesmaki H, Dunmire V, Feng Y, et al. (2004). Differential gene and protein expression in primary breast malignancies and their lymph node metastases as revealed by combined cDNA microarray and tissue microarray analysis. Cancer 100: 1110-1122.
    • (2004) Cancer , vol.100 , pp. 1110-1122
    • Hao, X.1    Sun, B.2    Hu, L.3    Lahdesmaki, H.4    Dunmire, V.5    Feng, Y.6
  • 45
    • 44449120976 scopus 로고    scopus 로고
    • Suppression of the invasive capacity of rat ascites hepatoma cells by knockdown of Slingshot or LIM kinase
    • Horita Y, Ohashi K, Mukai M, Inoue M, Mizuno K, (2008). Suppression of the invasive capacity of rat ascites hepatoma cells by knockdown of Slingshot or LIM kinase. J Biol Chem 283: 6013-6021.
    • (2008) J Biol Chem , vol.283 , pp. 6013-6021
    • Horita, Y.1    Ohashi, K.2    Mukai, M.3    Inoue, M.4    Mizuno, K.5
  • 46
    • 0038679226 scopus 로고    scopus 로고
    • Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma
    • Horiuchi A, Imai T, Wang C, Ohira S, Feng Y, Nikaido T, et al. (2003). Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma. Lab Invest 83: 861-870.
    • (2003) Lab Invest , vol.83 , pp. 861-870
    • Horiuchi, A.1    Imai, T.2    Wang, C.3    Ohira, S.4    Feng, Y.5    Nikaido, T.6
  • 47
    • 67949106668 scopus 로고    scopus 로고
    • Cortactin, fascin, and survivin expression associated with clinicopathological parameters in esophageal squamous cell carcinoma
    • Hsu KF, Lin CK, Yu CP, Tzao C, Lee SC, Lee YY, et al. (2009). Cortactin, fascin, and survivin expression associated with clinicopathological parameters in esophageal squamous cell carcinoma. Dis Esophagus 22: 402-408.
    • (2009) Dis Esophagus , vol.22 , pp. 402-408
    • Hsu, K.F.1    Lin, C.K.2    Yu, C.P.3    Tzao, C.4    Lee, S.C.5    Lee, Y.Y.6
  • 48
    • 0000463651 scopus 로고    scopus 로고
    • The structural and mechanical complexity of cell-growth control
    • Huang S, Ingber DE, (1999). The structural and mechanical complexity of cell-growth control. Nat Cell Biol 1: E131-E138.
    • (1999) Nat Cell Biol , vol.1 , pp. E131-E138
    • Huang, S.1    Ingber, D.E.2
  • 49
    • 79955929967 scopus 로고    scopus 로고
    • Nestin in gastrointestinal and other cancers: Effects on cells and tumor angiogenesis
    • Ishiwata T, Matsuda Y, Naito Z, (2011). Nestin in gastrointestinal and other cancers: effects on cells and tumor angiogenesis. World J Gastroenterol 17: 409-418.
    • (2011) World J Gastroenterol , vol.17 , pp. 409-418
    • Ishiwata, T.1    Matsuda, Y.2    Naito, Z.3
  • 50
    • 33847348959 scopus 로고    scopus 로고
    • Coexpression of Arp2 and WAVE2 predicts poor outcome in invasive breast carcinoma
    • Iwaya K, Norio K, Mukai K, (2007a). Coexpression of Arp2 and WAVE2 predicts poor outcome in invasive breast carcinoma. Mod Pathol 20: 339-343.
    • (2007) Mod Pathol , vol.20 , pp. 339-343
    • Iwaya, K.1    Norio, K.2    Mukai, K.3
  • 51
    • 34249914541 scopus 로고    scopus 로고
    • Correlation between liver metastasis of the colocalization of actin-related protein 2 and 3 complex and WAVE2 in colorectal carcinoma
    • Iwaya K, Oikawa K, Semba S, Tsuchiya B, Mukai Y, Otsubo T, et al. (2007b). Correlation between liver metastasis of the colocalization of actin-related protein 2 and 3 complex and WAVE2 in colorectal carcinoma. Cancer Sci 98: 992-999.
    • (2007) Cancer Sci , vol.98 , pp. 992-999
    • Iwaya, K.1    Oikawa, K.2    Semba, S.3    Tsuchiya, B.4    Mukai, Y.5    Otsubo, T.6
  • 52
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: Biochemistry and biology
    • Jaffe AB, Hall A, (2005). Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol 21: 247-269.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 53
    • 84876580519 scopus 로고    scopus 로고
    • Correlation between microtubule-associated gene expression and chemosensitivity of patients with stage II non-small cell lung cancer
    • Jiang H, Yu XM, Zhou XM, Wang XH, Su D, (2013). Correlation between microtubule-associated gene expression and chemosensitivity of patients with stage II non-small cell lung cancer. Exp Ther Med 5: 1506-1510.
    • (2013) Exp Ther Med , vol.5 , pp. 1506-1510
    • Jiang, H.1    Yu, X.M.2    Zhou, X.M.3    Wang, X.H.4    Su, D.5
  • 54
    • 1942438028 scopus 로고    scopus 로고
    • Microtubules as a target for anticancer drugs
    • Jordan MA, Wilson L, (2004). Microtubules as a target for anticancer drugs. Nat Rev Cancer 4: 253-265.
    • (2004) Nat Rev Cancer , vol.4 , pp. 253-265
    • Jordan, M.A.1    Wilson, L.2
  • 55
    • 0037817325 scopus 로고    scopus 로고
    • Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer
    • Kamai T, Tsujii T, Arai K, Takagi K, Asami H, Ito Y, et al. (2003). Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer. Clin Cancer Res 9: 2632-2641.
    • (2003) Clin Cancer Res , vol.9 , pp. 2632-2641
    • Kamai, T.1    Tsujii, T.2    Arai, K.3    Takagi, K.4    Asami, H.5    Ito, Y.6
  • 56
    • 3242699514 scopus 로고    scopus 로고
    • Overexpression of RhoA, Rac1, and Cdc42 GTPases is associated with progression in testicular cancer
    • Kamai T, Yamanishi T, Shirataki H, Takagi K, Asami H, Ito Y, et al. (2004). Overexpression of RhoA, Rac1, and Cdc42 GTPases is associated with progression in testicular cancer. Clin Cancer Res 10: 4799-4805.
    • (2004) Clin Cancer Res , vol.10 , pp. 4799-4805
    • Kamai, T.1    Yamanishi, T.2    Shirataki, H.3    Takagi, K.4    Asami, H.5    Ito, Y.6
  • 59
    • 77649191871 scopus 로고    scopus 로고
    • Microtubules and resistance to tubulin-binding agents
    • Kavallaris M, (2010). Microtubules and resistance to tubulin-binding agents. Nat Rev Cancer 10: 194-204.
    • (2010) Nat Rev Cancer , vol.10 , pp. 194-204
    • Kavallaris, M.1
  • 60
    • 82755184126 scopus 로고    scopus 로고
    • Regulation of cell migration by dynamic microtubules
    • Kaverina I, Straube A, (2011). Regulation of cell migration by dynamic microtubules. Semin Cell Dev Biol 22: 968-974.
    • (2011) Semin Cell Dev Biol , vol.22 , pp. 968-974
    • Kaverina, I.1    Straube, A.2
  • 61
    • 33646590920 scopus 로고    scopus 로고
    • Differential protein expression profiling by iTRAQ-2DLC-MS/MS of lung cancer cells undergoing epithelial-mesenchymal transition reveals a migratory/invasive phenotype
    • Keshamouni VG, Michailidis G, Grasso CS, Anthwal S, Strahler JR, Walker A, et al. (2006). Differential protein expression profiling by iTRAQ-2DLC-MS/MS of lung cancer cells undergoing epithelial-mesenchymal transition reveals a migratory/invasive phenotype. J Proteome Res 5: 1143-1154.
    • (2006) J Proteome Res , vol.5 , pp. 1143-1154
    • Keshamouni, V.G.1    Michailidis, G.2    Grasso, C.S.3    Anthwal, S.4    Strahler, J.R.5    Walker, A.6
  • 62
    • 0035328785 scopus 로고    scopus 로고
    • Metastasis-associated differences in gene expression in a murine model of osteosarcoma
    • Khanna C, Khan J, Nguyen P, Prehn J, Caylor J, Yeung C, et al. (2001). Metastasis-associated differences in gene expression in a murine model of osteosarcoma. Cancer Res 61: 3750-3759.
    • (2001) Cancer Res , vol.61 , pp. 3750-3759
    • Khanna, C.1    Khan, J.2    Nguyen, P.3    Prehn, J.4    Caylor, J.5    Yeung, C.6
  • 63
    • 11144357298 scopus 로고    scopus 로고
    • The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis
    • Khanna C, Wan X, Bose S, Cassaday R, Olomu O, Mendoza A, et al. (2004). The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis. Nat Med 10: 182-186.
    • (2004) Nat Med , vol.10 , pp. 182-186
    • Khanna, C.1    Wan, X.2    Bose, S.3    Cassaday, R.4    Olomu, O.5    Mendoza, A.6
  • 64
    • 77953230270 scopus 로고    scopus 로고
    • Regulation of cell adhesion to collagen via beta1 integrins is dependent on interactions of filamin A with vimentin and protein kinase C epsilon
    • Kim H, Nakamura F, Lee W, Hong C, Perez-Sala D, McCulloch CA, (2010a). Regulation of cell adhesion to collagen via beta1 integrins is dependent on interactions of filamin A with vimentin and protein kinase C epsilon. Exp Cell Res 316: 1829-1844.
    • (2010) Exp Cell Res , vol.316 , pp. 1829-1844
    • Kim, H.1    Nakamura, F.2    Lee, W.3    Hong, C.4    Perez-Sala, D.5    McCulloch, C.A.6
  • 66
    • 0036168355 scopus 로고    scopus 로고
    • Characterization of RhoC expression in benign and malignant breast disease: A potential new marker for small breast carcinomas with metastatic ability
    • Kleer CG, van Golen KL, Zhang Y, Wu ZF, Rubin MA, Merajver SD, (2002). Characterization of RhoC expression in benign and malignant breast disease: a potential new marker for small breast carcinomas with metastatic ability. Am J Pathol 160: 579-584.
    • (2002) Am J Pathol , vol.160 , pp. 579-584
    • Kleer, C.G.1    Van Golen, K.L.2    Zhang, Y.3    Wu, Z.F.4    Rubin, M.A.5    Merajver, S.D.6
  • 68
    • 67650115359 scopus 로고    scopus 로고
    • High expression of stathmin protein predicts a fulminant course in medulloblastoma
    • Kuo MF, Wang HS, Kuo QT, Shun CT, Hsu HC, Yang SH, et al. (2009). High expression of stathmin protein predicts a fulminant course in medulloblastoma. J Neurosurg Pediatr 4: 74-80.
    • (2009) J Neurosurg Pediatr , vol.4 , pp. 74-80
    • Kuo, M.F.1    Wang, H.S.2    Kuo, Q.T.3    Shun, C.T.4    Hsu, H.C.5    Yang, S.H.6
  • 69
    • 84894593599 scopus 로고    scopus 로고
    • Molecular mechanisms of epithelial-mesenchymal transition
    • Lamouille S, Xu J, Derynck R, (2014). Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol 15: 178-196.
    • (2014) Nat Rev Mol Cell Biol , vol.15 , pp. 178-196
    • Lamouille, S.1    Xu, J.2    Derynck, R.3
  • 70
    • 79953300698 scopus 로고    scopus 로고
    • The seed and soil hypothesis revisited-The role of tumor-stroma interactions in metastasis to different organs
    • Langley RR, Fidler IJ, (2011). The seed and soil hypothesis revisited-the role of tumor-stroma interactions in metastasis to different organs. Int J Cancer 128: 2527-2535.
    • (2011) Int J Cancer , vol.128 , pp. 2527-2535
    • Langley, R.R.1    Fidler, I.J.2
  • 71
    • 61349092242 scopus 로고    scopus 로고
    • Expression of survivin and cortactin in colorectal adenocarcinoma: Association with clinicopathological parameters
    • Lee YY, Yu CP, Lin CK, Nieh S, Hsu KF, Chiang H, et al. (2009). Expression of survivin and cortactin in colorectal adenocarcinoma: association with clinicopathological parameters. Dis Markers 26: 9-18.
    • (2009) Dis Markers , vol.26 , pp. 9-18
    • Lee, Y.Y.1    Yu, C.P.2    Lin, C.K.3    Nieh, S.4    Hsu, K.F.5    Chiang, H.6
  • 72
    • 79952534369 scopus 로고    scopus 로고
    • The actin-associating protein Tm5NM1 blocks mesenchymal motility without transition to amoeboid motility
    • Lees JG, Bach CT, Bradbury P, Paul A, Gunning PW, O'Neill GM, (2011). The actin-associating protein Tm5NM1 blocks mesenchymal motility without transition to amoeboid motility. Oncogene 30: 1241-1251.
    • (2011) Oncogene , vol.30 , pp. 1241-1251
    • Lees, J.G.1    Bach, C.T.2    Bradbury, P.3    Paul, A.4    Gunning, P.W.5    O'Neill, G.M.6
  • 73
    • 51049117743 scopus 로고    scopus 로고
    • Aberrant expression of cortactin and fascin are effective markers for pathogenesis, invasion, metastasis and prognosis of gastric carcinomas
    • Li X, Zheng H, Hara T, Takahashi H, Masuda S, Wang Z, et al. (2008). Aberrant expression of cortactin and fascin are effective markers for pathogenesis, invasion, metastasis and prognosis of gastric carcinomas. Int J Oncol 33: 69-79.
    • (2008) Int J Oncol , vol.33 , pp. 69-79
    • Li, X.1    Zheng, H.2    Hara, T.3    Takahashi, H.4    Masuda, S.5    Wang, Z.6
  • 74
    • 38349058006 scopus 로고    scopus 로고
    • PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility
    • Lim Y, Lim ST, Tomar A, Gardel M, Bernard-Trifilo JA, Chen XL, et al. (2008). PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility. J Cell Biol 180: 187-203.
    • (2008) J Cell Biol , vol.180 , pp. 187-203
    • Lim, Y.1    Lim, S.T.2    Tomar, A.3    Gardel, M.4    Bernard-Trifilo, J.A.5    Chen, X.L.6
  • 75
    • 84872674019 scopus 로고    scopus 로고
    • A hypothesis on the origin and evolution of tubulin
    • Luduena RF, (2013). A hypothesis on the origin and evolution of tubulin. Int Rev Cell Mol Biol 302: 41-185.
    • (2013) Int Rev Cell Mol Biol , vol.302 , pp. 41-185
    • Luduena, R.F.1
  • 76
    • 33846225205 scopus 로고    scopus 로고
    • Amplification and overexpression of CTTN (EMS1) contribute to the metastasis of esophageal squamous cell carcinoma by promoting cell migration and anoikis resistance
    • Luo ML, Shen XM, Zhang Y, Wei F, Xu X, Cai Y, et al. (2006). Amplification and overexpression of CTTN (EMS1) contribute to the metastasis of esophageal squamous cell carcinoma by promoting cell migration and anoikis resistance. Cancer Res 66: 11690-11699.
    • (2006) Cancer Res , vol.66 , pp. 11690-11699
    • Luo, M.L.1    Shen, X.M.2    Zhang, Y.3    Wei, F.4    Xu, X.5    Cai, Y.6
  • 77
    • 0033529620 scopus 로고    scopus 로고
    • Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase
    • Maekawa M, Ishizaki T, Boku S, Watanabe N, Fujita A, Iwamatsu A, et al. (1999). Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science 285: 895-898.
    • (1999) Science , vol.285 , pp. 895-898
    • Maekawa, M.1    Ishizaki, T.2    Boku, S.3    Watanabe, N.4    Fujita, A.5    Iwamatsu, A.6
  • 78
    • 41149173784 scopus 로고    scopus 로고
    • N-WASP is a putative tumour suppressor in breast cancer cells, in vitro and in vivo, and is associated with clinical outcome in patients with breast cancer
    • Martin TA, Pereira G, Watkins G, Mansel RE, Jiang WG, (2008). N-WASP is a putative tumour suppressor in breast cancer cells, in vitro and in vivo, and is associated with clinical outcome in patients with breast cancer. Clin Exp Metastasis 25: 97-108.
    • (2008) Clin Exp Metastasis , vol.25 , pp. 97-108
    • Martin, T.A.1    Pereira, G.2    Watkins, G.3    Mansel, R.E.4    Jiang, W.G.5
  • 79
    • 84874439129 scopus 로고    scopus 로고
    • A role for microtubules in endothelial cell protrusion in three-dimensional matrices
    • Martins GG, Kolega J, (2012). A role for microtubules in endothelial cell protrusion in three-dimensional matrices. Biol Cell 104: 271-286.
    • (2012) Biol Cell , vol.104 , pp. 271-286
    • Martins, G.G.1    Kolega, J.2
  • 80
    • 0034279330 scopus 로고    scopus 로고
    • Changes in tumorigenesis- and angiogenesis-related gene transcript abundance profiles in ovarian cancer detected by tailored high density cDNA arrays
    • Martoglio AM, Tom BD, Starkey M, Corps AN, Charnock-Jones DS, Smith SK, (2000). Changes in tumorigenesis- and angiogenesis-related gene transcript abundance profiles in ovarian cancer detected by tailored high density cDNA arrays. Mol Med 6: 750-765.
    • (2000) Mol Med , vol.6 , pp. 750-765
    • Martoglio, A.M.1    Tom, B.D.2    Starkey, M.3    Corps, A.N.4    Charnock-Jones, D.S.5    Smith, S.K.6
  • 81
    • 84860333485 scopus 로고    scopus 로고
    • Eribulin mesylate: A novel halichondrin B analogue for the treatment of metastatic breast cancer
    • McBride A, Butler SK, (2012). Eribulin mesylate: a novel halichondrin B analogue for the treatment of metastatic breast cancer. Am J Health Syst Pharm 69: 745-755.
    • (2012) Am J Health Syst Pharm , vol.69 , pp. 745-755
    • McBride, A.1    Butler, S.K.2
  • 82
    • 77953750777 scopus 로고    scopus 로고
    • BetaIII-tubulin is a multifunctional protein involved in drug sensitivity and tumorigenesis in non-small cell lung cancer
    • McCarroll JA, Gan PP, Liu M, Kavallaris M, (2010). betaIII-tubulin is a multifunctional protein involved in drug sensitivity and tumorigenesis in non-small cell lung cancer. Cancer Res 70: 4995-5003.
    • (2010) Cancer Res , vol.70 , pp. 4995-5003
    • McCarroll, J.A.1    Gan, P.P.2    Liu, M.3    Kavallaris, M.4
  • 84
    • 84877768725 scopus 로고    scopus 로고
    • ATIP3, a novel prognostic marker of breast cancer patient survival, limits cancer cell migration and slows metastatic progression by regulating microtubule dynamics
    • Molina A, Velot L, Ghouinem L, Abdelkarim M, Bouchet BP, Luissint AC, et al. (2013). ATIP3, a novel prognostic marker of breast cancer patient survival, limits cancer cell migration and slows metastatic progression by regulating microtubule dynamics. Cancer Res 73: 2905-2915.
    • (2013) Cancer Res , vol.73 , pp. 2905-2915
    • Molina, A.1    Velot, L.2    Ghouinem, L.3    Abdelkarim, M.4    Bouchet, B.P.5    Luissint, A.C.6
  • 85
    • 4444296491 scopus 로고    scopus 로고
    • Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation
    • Mouneimne G, Soon L, DesMarais V, Sidani M, Song X, Yip SC, et al. (2004). Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation. J Cell Biol 166: 697-708.
    • (2004) J Cell Biol , vol.166 , pp. 697-708
    • Mouneimne, G.1    Soon, L.2    Desmarais, V.3    Sidani, M.4    Song, X.5    Yip, S.C.6
  • 86
    • 33750948427 scopus 로고    scopus 로고
    • Spatial and temporal control of cofilin activity is required for directional sensing during chemotaxis
    • Mouneimne G, DesMarais V, Sidani M, Scemes E, Wang W, Song X, et al. (2006). Spatial and temporal control of cofilin activity is required for directional sensing during chemotaxis. Curr Biol 16: 2193-2205.
    • (2006) Curr Biol , vol.16 , pp. 2193-2205
    • Mouneimne, G.1    Desmarais, V.2    Sidani, M.3    Scemes, E.4    Wang, W.5    Song, X.6
  • 87
    • 1642322097 scopus 로고    scopus 로고
    • Stathmin-tubulin interaction gradients in motile and mitotic cells
    • Niethammer P, Bastiaens P, Karsenti E, (2004). Stathmin-tubulin interaction gradients in motile and mitotic cells. Science 303: 1862-1866.
    • (2004) Science , vol.303 , pp. 1862-1866
    • Niethammer, P.1    Bastiaens, P.2    Karsenti, E.3
  • 88
    • 0028961293 scopus 로고
    • Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
    • Nobes CD, Hall A, (1995). Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81: 53-62.
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 89
    • 4644314377 scopus 로고    scopus 로고
    • Microtubule-actin cross-talk at focal adhesions
    • Palazzo AF, Gundersen GG, (2002). Microtubule-actin cross-talk at focal adhesions. Sci STKE 2002: pe31.
    • (2002) Sci STKE , vol.2002 , pp. pe31
    • Palazzo, A.F.1    Gundersen, G.G.2
  • 90
    • 51349169486 scopus 로고    scopus 로고
    • Intermediate filament protein synemin contributes to the migratory properties of astrocytoma cells by influencing the dynamics of the actin cytoskeleton
    • Pan Y, Jing R, Pitre A, Williams BJ, Skalli O, (2008). Intermediate filament protein synemin contributes to the migratory properties of astrocytoma cells by influencing the dynamics of the actin cytoskeleton. FASEB J 22: 3196-3206.
    • (2008) FASEB J , vol.22 , pp. 3196-3206
    • Pan, Y.1    Jing, R.2    Pitre, A.3    Williams, B.J.4    Skalli, O.5
  • 91
    • 77955172181 scopus 로고    scopus 로고
    • Metronomic chemotherapy: New rationale for new directions
    • Pasquier E, Kavallaris M, Andre N, (2010). Metronomic chemotherapy: new rationale for new directions. Nat Rev Clin Oncol 7: 455-465.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 455-465
    • Pasquier, E.1    Kavallaris, M.2    Andre, N.3
  • 92
    • 84895070483 scopus 로고    scopus 로고
    • Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities
    • Patel RA, Liu Y, Wang B, Li R, Sebti SM, (2014). Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities. Oncogene 33: 550-555.
    • (2014) Oncogene , vol.33 , pp. 550-555
    • Patel, R.A.1    Liu, Y.2    Wang, B.3    Li, R.4    Sebti, S.M.5
  • 93
    • 34948885066 scopus 로고    scopus 로고
    • The Abl-related gene tyrosine kinase acts through p190RhoGAP to inhibit actomyosin contractility and regulate focal adhesion dynamics upon adhesion to fibronectin
    • Peacock JG, Miller AL, Bradley WD, Rodriguez OC, Webb DJ, Koleske AJ, (2007). The Abl-related gene tyrosine kinase acts through p190RhoGAP to inhibit actomyosin contractility and regulate focal adhesion dynamics upon adhesion to fibronectin. Mol Biol Cell 18: 3860-3872.
    • (2007) Mol Biol Cell , vol.18 , pp. 3860-3872
    • Peacock, J.G.1    Miller, A.L.2    Bradley, W.D.3    Rodriguez, O.C.4    Webb, D.J.5    Koleske, A.J.6
  • 94
    • 36248969983 scopus 로고    scopus 로고
    • Actin stress fibres
    • Pellegrin S, Mellor H, (2007). Actin stress fibres. J Cell Sci 120 (Pt 20): 3491-3499.
    • (2007) J Cell Sci , vol.120 , Issue.PART 20 , pp. 3491-3499
    • Pellegrin, S.1    Mellor, H.2
  • 95
    • 0034841005 scopus 로고    scopus 로고
    • Vertebrate tropomyosin: Distribution, properties and function
    • Perry SV, (2001). Vertebrate tropomyosin: distribution, properties and function. J Muscle Res Cell Motil 22: 5-49.
    • (2001) J Muscle Res Cell Motil , vol.22 , pp. 5-49
    • Perry, S.V.1
  • 96
    • 0037459075 scopus 로고    scopus 로고
    • Cellular motility driven by assembly and disassembly of actin filaments
    • Pollard TD, Borisy GG, (2003). Cellular motility driven by assembly and disassembly of actin filaments. Cell 112: 453-465.
    • (2003) Cell , vol.112 , pp. 453-465
    • Pollard, T.D.1    Borisy, G.G.2
  • 97
    • 75749117154 scopus 로고    scopus 로고
    • LIM-kinase 2, a regulator of actin dynamics, is involved in mitotic spindle integrity and sensitivity to microtubule-destabilizing drugs
    • Po'uha ST, Shum MS, Goebel A, Bernard O, Kavallaris M, (2010). LIM-kinase 2, a regulator of actin dynamics, is involved in mitotic spindle integrity and sensitivity to microtubule-destabilizing drugs. Oncogene 29: 597-607.
    • (2010) Oncogene , vol.29 , pp. 597-607
    • Po'Uha, S.T.1    Shum, M.S.2    Goebel, A.3    Bernard, O.4    Kavallaris, M.5
  • 99
    • 84865745556 scopus 로고    scopus 로고
    • Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth
    • Prudent R, Vassal-Stermann E, Nguyen CH, Pillet C, Martinez A, Prunier C, et al. (2012). Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth. Cancer Res 72: 4429-4439.
    • (2012) Cancer Res , vol.72 , pp. 4429-4439
    • Prudent, R.1    Vassal-Stermann, E.2    Nguyen, C.H.3    Pillet, C.4    Martinez, A.5    Prunier, C.6
  • 100
    • 84867024393 scopus 로고    scopus 로고
    • Rho-associated kinases in tumorigenesis: Re-considering ROCK inhibition for cancer therapy
    • Rath N, Olson MF, (2012). Rho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapy. EMBO Rep 13: 900-908.
    • (2012) EMBO Rep , vol.13 , pp. 900-908
    • Rath, N.1    Olson, M.F.2
  • 103
    • 62849094790 scopus 로고    scopus 로고
    • Distinctive clinicopathological associations of amplification of the cortactin gene at 11q13 in head and neck squamous cell carcinomas
    • Rodrigo JP, Garcia-Carracedo D, Garcia LA, Menendez S, Allonca E, Gonzalez MV, et al. (2009). Distinctive clinicopathological associations of amplification of the cortactin gene at 11q13 in head and neck squamous cell carcinomas. J Pathol 217: 516-523.
    • (2009) J Pathol , vol.217 , pp. 516-523
    • Rodrigo, J.P.1    Garcia-Carracedo, D.2    Garcia, L.A.3    Menendez, S.4    Allonca, E.5    Gonzalez, M.V.6
  • 104
    • 70349690097 scopus 로고    scopus 로고
    • 8p22 MTUS1 gene product ATIP3 is a novel anti-mitotic protein underexpressed in invasive breast carcinoma of poor prognosis
    • Rodrigues-Ferreira S, Di Tommaso A, Dimitrov A, Cazaubon S, Gruel N, Colasson H, et al. (2009). 8p22 MTUS1 gene product ATIP3 is a novel anti-mitotic protein underexpressed in invasive breast carcinoma of poor prognosis. PLoS ONE 4: e7239.
    • (2009) PLoS ONE , vol.4 , pp. e7239
    • Rodrigues-Ferreira, S.1    Di Tommaso, A.2    Dimitrov, A.3    Cazaubon, S.4    Gruel, N.5    Colasson, H.6
  • 105
    • 56249118731 scopus 로고    scopus 로고
    • Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors
    • Ross-Macdonald P, de Silva H, Guo Q, Xiao H, Hung CY, Penhallow B, et al. (2008). Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors. Mol Cancer Ther 7: 3490-3498.
    • (2008) Mol Cancer Ther , vol.7 , pp. 3490-3498
    • Ross-Macdonald, P.1    De Silva, H.2    Guo, Q.3    Xiao, H.4    Hung, C.Y.5    Penhallow, B.6
  • 106
    • 13444252631 scopus 로고    scopus 로고
    • GEF means go: Turning on RHO GTPases with guanine nucleotide-exchange factors
    • Rossman KL, Der CJ, Sondek J, (2005). GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat Rev Mol Cell Biol 6: 167-180.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 167-180
    • Rossman, K.L.1    Der, C.J.2    Sondek, J.3
  • 107
    • 84871519238 scopus 로고    scopus 로고
    • New insights into the regulation and cellular functions of the ARP2/3 complex
    • Rotty JD, Wu C, Bear JE, (2013). New insights into the regulation and cellular functions of the ARP2/3 complex. Nat Rev Mol Cell Biol 14: 7-12.
    • (2013) Nat Rev Mol Cell Biol , vol.14 , pp. 7-12
    • Rotty, J.D.1    Wu, C.2    Bear, J.E.3
  • 109
    • 0042354574 scopus 로고    scopus 로고
    • Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
    • Sahai E, Marshall CJ, (2003). Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis. Nat Cell Biol 5: 711-719.
    • (2003) Nat Cell Biol , vol.5 , pp. 711-719
    • Sahai, E.1    Marshall, C.J.2
  • 110
    • 80052267874 scopus 로고    scopus 로고
    • Vimentin in cancer and its potential as a molecular target for cancer therapy
    • Satelli A, Li S, (2011). Vimentin in cancer and its potential as a molecular target for cancer therapy. Cell Mol Life Sci 68: 3033-3046.
    • (2011) Cell Mol Life Sci , vol.68 , pp. 3033-3046
    • Satelli, A.1    Li, S.2
  • 111
    • 0842281489 scopus 로고    scopus 로고
    • Multiple connections link FAK to cell motility and invasion
    • Schlaepfer DD, Mitra SK, (2004). Multiple connections link FAK to cell motility and invasion. Curr Opin Genet Dev 14: 92-101.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 92-101
    • Schlaepfer, D.D.1    Mitra, S.K.2
  • 114
    • 77957732541 scopus 로고    scopus 로고
    • LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells
    • Scott RW, Hooper S, Crighton D, Li A, Konig I, Munro J, et al. (2010). LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells. J Cell Biol 191: 169-185.
    • (2010) J Cell Biol , vol.191 , pp. 169-185
    • Scott, R.W.1    Hooper, S.2    Crighton, D.3    Li, A.4    Konig, I.5    Munro, J.6
  • 115
    • 33646397828 scopus 로고    scopus 로고
    • Coexpression of actin-related protein 2 and Wiskott-Aldrich syndrome family verproline-homologous protein 2 in adenocarcinoma of the lung
    • Semba S, Iwaya K, Matsubayashi J, Serizawa H, Kataba H, Hirano T, et al. (2006). Coexpression of actin-related protein 2 and Wiskott-Aldrich syndrome family verproline-homologous protein 2 in adenocarcinoma of the lung. Clin Cancer Res 12: 2449-2454.
    • (2006) Clin Cancer Res , vol.12 , pp. 2449-2454
    • Semba, S.1    Iwaya, K.2    Matsubayashi, J.3    Serizawa, H.4    Kataba, H.5    Hirano, T.6
  • 117
    • 34249714850 scopus 로고    scopus 로고
    • Role of phosphorylation on the structural dynamics and function of types III and IV intermediate filaments
    • Sihag RK, Inagaki M, Yamaguchi T, Shea TB, Pant HC, (2007). Role of phosphorylation on the structural dynamics and function of types III and IV intermediate filaments. Exp Cell Res 313: 2098-2109.
    • (2007) Exp Cell Res , vol.313 , pp. 2098-2109
    • Sihag, R.K.1    Inagaki, M.2    Yamaguchi, T.3    Shea, T.B.4    Pant, H.C.5
  • 118
    • 0344131934 scopus 로고    scopus 로고
    • Increased expression of epidermal fatty acid binding protein, cofilin, and 14-3-3-sigma (stratifin) detected by two-dimensional gel electrophoresis, mass spectrometry and microsequencing of drug-resistant human adenocarcinoma of the pancreas
    • Sinha P, Hutter G, Kottgen E, Dietel M, Schadendorf D, Lage H, (1999). Increased expression of epidermal fatty acid binding protein, cofilin, and 14-3-3-sigma (stratifin) detected by two-dimensional gel electrophoresis, mass spectrometry and microsequencing of drug-resistant human adenocarcinoma of the pancreas. Electrophoresis 20: 2952-2960.
    • (1999) Electrophoresis , vol.20 , pp. 2952-2960
    • Sinha, P.1    Hutter, G.2    Kottgen, E.3    Dietel, M.4    Schadendorf, D.5    Lage, H.6
  • 120
    • 0021077837 scopus 로고
    • Distinct patterns of cytoplasmic protein phosphorylation related to regulation of synthesis and release of prolactin by GH cells
    • Sobel A, Tashjian AH Jr, (1983). Distinct patterns of cytoplasmic protein phosphorylation related to regulation of synthesis and release of prolactin by GH cells. J Biol Chem 258: 10312-10324.
    • (1983) J Biol Chem , vol.258 , pp. 10312-10324
    • Sobel, A.1    Tashjian, A.H.2
  • 121
    • 33746851956 scopus 로고    scopus 로고
    • Tumor metastasis: Mechanistic insights and clinical challenges
    • Steeg PS, (2006). Tumor metastasis: mechanistic insights and clinical challenges. Nat Med 12: 895-904.
    • (2006) Nat Med , vol.12 , pp. 895-904
    • Steeg, P.S.1
  • 122
    • 84882680799 scopus 로고    scopus 로고
    • A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells
    • Stehn JR, Haass NK, Bonello T, Desouza M, Kottyan G, Treutlein H, et al. (2013). A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells. Cancer Res 73: 5169-5182.
    • (2013) Cancer Res , vol.73 , pp. 5169-5182
    • Stehn, J.R.1    Haass, N.K.2    Bonello, T.3    Desouza, M.4    Kottyan, G.5    Treutlein, H.6
  • 123
    • 84863081067 scopus 로고    scopus 로고
    • WAVE2 protein complex coupled to membrane and microtubules
    • Takahashi K, (2012). WAVE2 protein complex coupled to membrane and microtubules. J Oncol 2012: 590531.
    • (2012) J Oncol , vol.2012 , pp. 590531
    • Takahashi, K.1
  • 125
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY, Nieto MA, (2009). Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 126
    • 60749130633 scopus 로고    scopus 로고
    • Aberrant expression of human ortholog of mammalian enabled (hMena) in human colorectal carcinomas: Implications for its role in tumor progression
    • Toyoda A, Kawana H, Azuhata K, Yu J, Omata A, Kishi H, et al. (2009). Aberrant expression of human ortholog of mammalian enabled (hMena) in human colorectal carcinomas: implications for its role in tumor progression. Int J Oncol 34: 53-60.
    • (2009) Int J Oncol , vol.34 , pp. 53-60
    • Toyoda, A.1    Kawana, H.2    Azuhata, K.3    Yu, J.4    Omata, A.5    Kishi, H.6
  • 127
    • 79956000555 scopus 로고    scopus 로고
    • Stathmin overexpression identifies high-risk patients and lymph node metastasis in endometrial cancer
    • Trovik J, Wik E, Stefansson IM, Marcickiewicz J, Tingulstad S, Staff AC, et al. (2011). Stathmin overexpression identifies high-risk patients and lymph node metastasis in endometrial cancer. Clin Cancer Res 17: 3368-3377.
    • (2011) Clin Cancer Res , vol.17 , pp. 3368-3377
    • Trovik, J.1    Wik, E.2    Stefansson, I.M.3    Marcickiewicz, J.4    Tingulstad, S.5    Staff, A.C.6
  • 128
    • 0347513188 scopus 로고    scopus 로고
    • The vimentin cytoskeleton regulates focal contact size and adhesion of endothelial cells subjected to shear stress
    • Tsuruta D, Jones JC, (2003). The vimentin cytoskeleton regulates focal contact size and adhesion of endothelial cells subjected to shear stress. J Cell Sci 116 (Pt 24): 4977-4984.
    • (2003) J Cell Sci , vol.116 , Issue.PART 24 , pp. 4977-4984
    • Tsuruta, D.1    Jones, J.C.2
  • 129
    • 33645824753 scopus 로고    scopus 로고
    • Identification of differentially expressed, tumor-associated proteins in oral squamous cell carcinoma by proteomic analysis
    • Turhani D, Krapfenbauer K, Thurnher D, Langen H, Fountoulakis M, (2006). Identification of differentially expressed, tumor-associated proteins in oral squamous cell carcinoma by proteomic analysis. Electrophoresis 27: 1417-1423.
    • (2006) Electrophoresis , vol.27 , pp. 1417-1423
    • Turhani, D.1    Krapfenbauer, K.2    Thurnher, D.3    Langen, H.4    Fountoulakis, M.5
  • 130
    • 70249085230 scopus 로고    scopus 로고
    • Rho family GTPases and their regulators in lymphocytes
    • Tybulewicz VL, Henderson RB, (2009). Rho family GTPases and their regulators in lymphocytes. Nat Rev Immunol 9: 630-644.
    • (2009) Nat Rev Immunol , vol.9 , pp. 630-644
    • Tybulewicz, V.L.1    Henderson, R.B.2
  • 131
    • 78650526701 scopus 로고    scopus 로고
    • Common themes in centriole and centrosome movements
    • Vaughan S, Dawe HR, (2011). Common themes in centriole and centrosome movements. Trends Cell Biol 21: 57-66.
    • (2011) Trends Cell Biol , vol.21 , pp. 57-66
    • Vaughan, S.1    Dawe, H.R.2
  • 132
    • 44449178868 scopus 로고    scopus 로고
    • Rho GTPases in cancer cell biology
    • Vega FM, Ridley AJ, (2008). Rho GTPases in cancer cell biology. FEBS Lett 582: 2093-2101.
    • (2008) FEBS Lett , vol.582 , pp. 2093-2101
    • Vega, F.M.1    Ridley, A.J.2
  • 133
  • 134
    • 33645066349 scopus 로고    scopus 로고
    • Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia - An in vivo study
    • Verrills NM, Liem NL, Liaw TY, Hood BD, Lock RB, Kavallaris M, (2006a). Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia-an in vivo study. Proteomics 6: 1681-1694.
    • (2006) Proteomics , vol.6 , pp. 1681-1694
    • Verrills, N.M.1    Liem, N.L.2    Liaw, T.Y.3    Hood, B.D.4    Lock, R.B.5    Kavallaris, M.6
  • 136
    • 84877997158 scopus 로고    scopus 로고
    • Focal adhesion kinase overexpression: Correlation with lymph node metastasis and shorter survival in oral squamous cell carcinoma
    • de Vicente JC, Rosado P, Lequerica-Fernandez P, Allonca E, Villallain L, Hernandez-Vallejo G, (2013). Focal adhesion kinase overexpression: correlation with lymph node metastasis and shorter survival in oral squamous cell carcinoma. Head Neck 35: 826-830.
    • (2013) Head Neck , vol.35 , pp. 826-830
    • De Vicente, J.C.1    Rosado, P.2    Lequerica-Fernandez, P.3    Allonca, E.4    Villallain, L.5    Hernandez-Vallejo, G.6
  • 137
    • 9244222742 scopus 로고    scopus 로고
    • Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors
    • Wang W, Goswami S, Lapidus K, Wells AL, Wyckoff JB, Sahai E, et al. (2004). Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors. Cancer Res 64: 8585-8594.
    • (2004) Cancer Res , vol.64 , pp. 8585-8594
    • Wang, W.1    Goswami, S.2    Lapidus, K.3    Wells, A.L.4    Wyckoff, J.B.5    Sahai, E.6
  • 138
    • 33646386905 scopus 로고    scopus 로고
    • The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors
    • Wang W, Mouneimne G, Sidani M, Wyckoff J, Chen X, Makris A, et al. (2006). The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors. J Cell Biol 173: 395-404.
    • (2006) J Cell Biol , vol.173 , pp. 395-404
    • Wang, W.1    Mouneimne, G.2    Sidani, M.3    Wyckoff, J.4    Chen, X.5    Makris, A.6
  • 139
    • 34249281332 scopus 로고    scopus 로고
    • The cofilin pathway in breast cancer invasion and metastasis
    • Wang W, Eddy R, Condeelis J, (2007). The cofilin pathway in breast cancer invasion and metastasis. Nat Rev Cancer 7: 429-440.
    • (2007) Nat Rev Cancer , vol.7 , pp. 429-440
    • Wang, W.1    Eddy, R.2    Condeelis, J.3
  • 140
    • 77955939239 scopus 로고    scopus 로고
    • The expression of CFL1 and N-WASP in esophageal squamous cell carcinoma and its correlation with clinicopathological features
    • Wang WS, Zhong HJ, Xiao DW, Huang X, Liao LD, Xie ZF, et al. (2010a). The expression of CFL1 and N-WASP in esophageal squamous cell carcinoma and its correlation with clinicopathological features. Dis Esophagus 23: 512-521.
    • (2010) Dis Esophagus , vol.23 , pp. 512-521
    • Wang, W.S.1    Zhong, H.J.2    Xiao, D.W.3    Huang, X.4    Liao, L.D.5    Xie, Z.F.6
  • 141
    • 77956580659 scopus 로고    scopus 로고
    • VEGF and cortactin expression are independent predictors of tumor recurrence following curative resection of gastric cancer
    • Wang X, Cao W, Mo M, Wang W, Wu H, Wang J, (2010b). VEGF and cortactin expression are independent predictors of tumor recurrence following curative resection of gastric cancer. J Surg Oncol 102: 325-330.
    • (2010) J Surg Oncol , vol.102 , pp. 325-330
    • Wang, X.1    Cao, W.2    Mo, M.3    Wang, W.4    Wu, H.5    Wang, J.6
  • 142
    • 37549043960 scopus 로고    scopus 로고
    • Prognostic significance of stathmin expression in correlation with metastasis and clinicopathological characteristics in human ovarian carcinoma
    • Wei SH, Lin F, Wang X, Gao P, Zhang HZ, (2008). Prognostic significance of stathmin expression in correlation with metastasis and clinicopathological characteristics in human ovarian carcinoma. Acta Histochem 110: 59-65.
    • (2008) Acta Histochem , vol.110 , pp. 59-65
    • Wei, S.H.1    Lin, F.2    Wang, X.3    Gao, P.4    Zhang, H.Z.5
  • 143
    • 0035178210 scopus 로고    scopus 로고
    • Cell motility: Can Rho GTPases and microtubules point the way?
    • Wittmann T, Waterman-Storer CM, (2001). Cell motility: can Rho GTPases and microtubules point the way? J Cell Sci 114 (Pt 21): 3795-3803.
    • (2001) J Cell Sci , vol.114 , Issue.PART 21 , pp. 3795-3803
    • Wittmann, T.1    Waterman-Storer, C.M.2
  • 144
    • 1242271991 scopus 로고    scopus 로고
    • Regulation of microtubule destabilizing activity of Op18/stathmin downstream of Rac1
    • Wittmann T, Bokoch GM, Waterman-Storer CM, (2004). Regulation of microtubule destabilizing activity of Op18/stathmin downstream of Rac1. J Biol Chem 279: 6196-6203.
    • (2004) J Biol Chem , vol.279 , pp. 6196-6203
    • Wittmann, T.1    Bokoch, G.M.2    Waterman-Storer, C.M.3
  • 145
    • 33746562929 scopus 로고    scopus 로고
    • ROCK- and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo
    • Wyckoff JB, Pinner SE, Gschmeissner S, Condeelis JS, Sahai E, (2006). ROCK- and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo. Curr Biol 16: 1515-1523.
    • (2006) Curr Biol , vol.16 , pp. 1515-1523
    • Wyckoff, J.B.1    Pinner, S.E.2    Gschmeissner, S.3    Condeelis, J.S.4    Sahai, E.5
  • 146
    • 76349088746 scopus 로고    scopus 로고
    • Cytoskeleton alterations in melanoma: Aberrant expression of cortactin, an actin-binding adapter protein, correlates with melanocytic tumor progression
    • Xu XZ, Garcia MV, Li TY, Khor LY, Gajapathy RS, Spittle C, et al. (2010). Cytoskeleton alterations in melanoma: aberrant expression of cortactin, an actin-binding adapter protein, correlates with melanocytic tumor progression. Mod Pathol 23: 187-196.
    • (2010) Mod Pathol , vol.23 , pp. 187-196
    • Xu, X.Z.1    Garcia, M.V.2    Li, T.Y.3    Khor, L.Y.4    Gajapathy, R.S.5    Spittle, C.6
  • 147
    • 78149407779 scopus 로고    scopus 로고
    • Overexpression of cortactin increases invasion potential in oral squamous cell carcinoma
    • Yamada S, Yanamoto S, Kawasaki G, Mizuno A, Nemoto TK, (2010). Overexpression of cortactin increases invasion potential in oral squamous cell carcinoma. Pathol Oncol Res 16: 523-531.
    • (2010) Pathol Oncol Res , vol.16 , pp. 523-531
    • Yamada, S.1    Yanamoto, S.2    Kawasaki, G.3    Mizuno, A.4    Nemoto, T.K.5
  • 148
    • 34247468876 scopus 로고    scopus 로고
    • Regulation of the actin cytoskeleton in cancer cell migration and invasion
    • Yamaguchi H, Condeelis J, (2007). Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim Biophys Acta 1773: 642-652.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 642-652
    • Yamaguchi, H.1    Condeelis, J.2
  • 149
    • 0034769874 scopus 로고    scopus 로고
    • Genome-wide screening of genes showing altered expression in liver metastases of human colorectal cancers by cDNA microarray
    • Yanagawa R, Furukawa Y, Tsunoda T, Kitahara O, Kameyama M, Murata K, et al. (2001). Genome-wide screening of genes showing altered expression in liver metastases of human colorectal cancers by cDNA microarray. Neoplasia 3: 395-401.
    • (2001) Neoplasia , vol.3 , pp. 395-401
    • Yanagawa, R.1    Furukawa, Y.2    Tsunoda, T.3    Kitahara, O.4    Kameyama, M.5    Murata, K.6
  • 150
    • 0034810439 scopus 로고    scopus 로고
    • RhoA/rho-associated kinase mediates fibroblast contractile force generation
    • Yee HF Jr, Melton AC, Tran BN, (2001). RhoA/rho-associated kinase mediates fibroblast contractile force generation. Biochem Biophys Res Commun 280: 1340-1345.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 1340-1345
    • Yee, H.F.1    Melton, A.C.2    Tran, B.N.3
  • 151
    • 16844362958 scopus 로고    scopus 로고
    • Hypoxia stimulates carcinoma invasion by stabilizing microtubules and promoting the Rab11 trafficking of the alpha6beta4 integrin
    • Yoon SO, Shin S, Mercurio AM, (2005). Hypoxia stimulates carcinoma invasion by stabilizing microtubules and promoting the Rab11 trafficking of the alpha6beta4 integrin. Cancer Res 65: 2761-2769.
    • (2005) Cancer Res , vol.65 , pp. 2761-2769
    • Yoon, S.O.1    Shin, S.2    Mercurio, A.M.3
  • 152
    • 84896489562 scopus 로고    scopus 로고
    • Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states
    • Yoshida T, Ozawa Y, Kimura T, Sato Y, Kuznetsov G, Xu S, et al. (2014). Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states. Br J Cancer 101: 1497-1505.
    • (2014) Br J Cancer , vol.101 , pp. 1497-1505
    • Yoshida, T.1    Ozawa, Y.2    Kimura, T.3    Sato, Y.4    Kuznetsov, G.5    Xu, S.6
  • 153
    • 1442304609 scopus 로고    scopus 로고
    • Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators
    • Yu Y, Khan J, Khanna C, Helman L, Meltzer PS, Merlino G, (2004). Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators. Nat Med 10: 175-181.
    • (2004) Nat Med , vol.10 , pp. 175-181
    • Yu, Y.1    Khan, J.2    Khanna, C.3    Helman, L.4    Meltzer, P.S.5    Merlino, G.6
  • 154
    • 67650535473 scopus 로고    scopus 로고
    • Microtubule plus-end binding protein EB1 is necessary for muscle cell differentiation, elongation and fusion
    • Zhang T, Zaal KJ, Sheridan J, Mehta A, Gundersen GG, Ralston E, (2009). Microtubule plus-end binding protein EB1 is necessary for muscle cell differentiation, elongation and fusion. J Cell Sci 122 (Pt 9): 1401-1409.
    • (2009) J Cell Sci , vol.122 , Issue.PART 9 , pp. 1401-1409
    • Zhang, T.1    Zaal, K.J.2    Sheridan, J.3    Mehta, A.4    Gundersen, G.G.5    Ralston, E.6
  • 155
    • 54049106041 scopus 로고    scopus 로고
    • Overexpression of FMNL2 is closely related to metastasis of colorectal cancer
    • Zhu XL, Liang L, Ding YQ, (2008). Overexpression of FMNL2 is closely related to metastasis of colorectal cancer. Int J Colorectal Dis 23: 1041-1047.
    • (2008) Int J Colorectal Dis , vol.23 , pp. 1041-1047
    • Zhu, X.L.1    Liang, L.2    Ding, Y.Q.3


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