LIM-kinase 2, a regulator of actin dynamics, is involved in mitotic spindle integrity and sensitivity to microtubule-destabilizing drugs

Oncogene

Volumn 29, Issue 4, 2010, Pages 597-607

  Po'Uha, S T ^a,b   Shum, M S Y ^a,b   Goebel, A ^a   Bernard, O ^c,d   Kavallaris, M ^a  

^a CHILDREN S CANCER INSTITUTE AUSTRALIA FOR MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d ST VINCENT S HOSPITAL   (Australia)

Author keywords

Drug sensitivity; LIM kinase 2; Microtubuledestabilizing drugs; Mitosis; Neuroblastoma

Indexed keywords

COFILIN; COLCHICINE; LIM KINASE; LIM KINASE 1; LIM KINASE 2; UNCLASSIFIED DRUG; VINBLASTINE; VINCA ALKALOID; VINCRISTINE; ACTIN; ACTIN DEPOLYMERIZING FACTOR; EPOTHILONE B; EPOTHILONE DERIVATIVE; LIMK2 PROTEIN, HUMAN; TUBULIN MODULATOR;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG SENSITIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MICROTUBULE; MITOSIS INHIBITION; MITOSIS SPINDLE; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STRESS FIBER; CELL SURVIVAL; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NEUROBLASTOMA; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE;

ACTIN DEPOLYMERIZING FACTORS; ACTINS; CELL LINE, TUMOR; CELL SURVIVAL; EPOTHILONES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIM KINASES; MICROTUBULES; MITOTIC SPINDLE APPARATUS; NEUROBLASTOMA; PHOSPHORYLATION; TUBULIN MODULATORS; VINCRISTINE;

EID: 75749117154     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.367     Document Type: Article

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