메뉴 건너뛰기




Volumn , Issue , 2012, Pages

Advancements in the treatment of metastatic breast cancer (MBC): The role of ixabepilone

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE DERIVATIVE; BEVACIZUMAB; BRCA1 PROTEIN; BRCA2 PROTEIN; CAPECITABINE; CARBOPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERIBULIN; GEMCITABINE; INIPARIB; IXABEPILONE; NAVELBINE; PACLITAXEL; TAXANE DERIVATIVE; TRASTUZUMAB;

EID: 84862301244     PISSN: 16878450     EISSN: 16878469     Source Type: Journal    
DOI: 10.1155/2012/703858     Document Type: Review
Times cited : (10)

References (60)
  • 2
    • 84862289130 scopus 로고    scopus 로고
    • ACS. Cancer Facts Figures, 2011
    • ACS. Cancer Facts Figures, 2011, http://www.cancer.org/acs/groups/ content/@epidemiologysurveilance/documents/document/acspc-029771.pdf
  • 3
    • 68449084678 scopus 로고    scopus 로고
    • Metastatic breast cancer: Therapeutic options according to molecular subtypes and prior adjuvant therapy
    • Guarneri V., Conte P., Metastatic breast cancer: therapeutic options according to molecular subtypes and prior adjuvant therapy Oncologist 2009 14 7 645 656
    • (2009) Oncologist , vol.14 , Issue.7 , pp. 645-656
    • Guarneri, V.1    Conte, P.2
  • 8
    • 28944436711 scopus 로고    scopus 로고
    • Microtubule targeting agents: Basic mechanisms of multidrug resistance (MDR)
    • Fojo A. T., Menefee M., Microtubule targeting agents: basic mechanisms of multidrug resistance (MDR) Seminars in Oncology 2005 32 7 S3 S8
    • (2005) Seminars in Oncology , vol.32 , Issue.7
    • Fojo, A.T.1    Menefee, M.2
  • 10
    • 0031040149 scopus 로고    scopus 로고
    • The development and clinical utility of the taxane class of antimicrotubule chemotherapy agents
    • DOI 10.1146/annurev.med.48.1.353
    • Rowinsky E. K., The development and clinical utility of the taxane class of antimicrotubule chemotherapy agents Annual Review of Medicine 1997 48 353 374 (Pubitemid 27101837)
    • (1997) Annual Review of Medicine , vol.48 , pp. 353-374
    • Rowinsky, E.K.1
  • 11
    • 79959503213 scopus 로고    scopus 로고
    • Triple-negative breast cancer: An unmet medical need
    • Hudis C. A., Gianni L., Triple-negative breast cancer: an unmet medical need The oncologist 2011 16, supplement 1 1 11
    • (2011) The Oncologist , vol.161 , pp. 1-11
    • Hudis, C.A.1    Gianni, L.2
  • 12
    • 0345688612 scopus 로고    scopus 로고
    • Mechanisms of Taxol resistance related to microtubules
    • 47 DOI 10.1038/sj.onc.1206934, Drug Resistance
    • Orr G. A., Verdier-Pinard P., McDaid H., Horwitz S. B., Mechanisms of Taxol resistance related to microtubules Oncogene 2003 22 47 7280 7295 (Pubitemid 37487160)
    • (2003) Oncogene , vol.22 , pp. 7280-7295
    • Orr, G.A.1    Verdier-Pinard, P.2    McDaid, H.3    Horwitz, S.B.4
  • 13
    • 0041820227 scopus 로고    scopus 로고
    • Expression of class III -tubulin reduces microtubule assembly and confers resistance to paclitaxel
    • DOI 10.1002/cm.10132
    • Hari M., Yang H., Zeng C., Canizales M., Cabral F., Expression of class III -tubulin reduces microtubule assembly and confers resistance to paclitaxel Cell Motility and the Cytoskeleton 2003 56 1 45 56 (Pubitemid 37059485)
    • (2003) Cell Motility and the Cytoskeleton , vol.56 , Issue.1 , pp. 45-56
    • Hari, M.1    Yang, H.2    Zeng, C.3    Canizales, M.4    Cabral, F.5
  • 14
    • 23444443007 scopus 로고    scopus 로고
    • Alterations of -tubulin isotypes in breast cancer cells resistant to docetaxel
    • DOI 10.1096/fj.04-3178fje
    • Shalli K., Brown I., Heys S. D., Schofield A. C., Alterations of -tubulin isotypes in breast cancer cells resistant to docetaxel FASEB Journal 2005 19 10 1299 1301 (Pubitemid 41113729)
    • (2005) FASEB Journal , vol.19 , Issue.10 , pp. 1299-1301
    • Shalli, K.1    Brown, I.2    Heys, S.D.3    Schofield, A.C.4
  • 16
    • 65949124480 scopus 로고    scopus 로고
    • Defective repair of oxidative DNA damage in triple-negative breast cancer confers sensitivity to inhibition of poly(ADP-ribose) polymerase
    • Alli E., Sharma V. B., Sunderesakumar P., Ford J. M., Defective repair of oxidative DNA damage in triple-negative breast cancer confers sensitivity to inhibition of poly(ADP-ribose) polymerase Cancer Research 2009 69 8 3589 3596
    • (2009) Cancer Research , vol.69 , Issue.8 , pp. 3589-3596
    • Alli, E.1    Sharma, V.B.2    Sunderesakumar, P.3    Ford, J.M.4
  • 21
    • 80052330662 scopus 로고    scopus 로고
    • A randomized phase III study of iniparib (BSI-201) in combination with gemcitabine/carboplatin (G/C) in metastatic triple-negative breast cancer (TNBC)
    • ABSTRACT 1007
    • OShaughnessy J., Schwartzberg L. S., Danso M. A., A randomized phase III study of iniparib (BSI-201) in combination with gemcitabine/carboplatin (G/C) in metastatic triple-negative breast cancer (TNBC) Journal of Clinical Oncology 2011 29 supplement 15s, abstract 1007
    • (2011) Journal of Clinical Oncology , vol.29 , Issue.SUPPL. 15S
    • Oshaughnessy, J.1    Schwartzberg, L.S.2    Danso, M.A.3
  • 23
    • 0037177229 scopus 로고    scopus 로고
    • Epothilone and paclitaxel: Unexpected differences in promoting the assembly and stabilization of yeast microtubules
    • DOI 10.1021/bi0121611
    • Bode C. J., Gupta M. L., Reiff E. A., Suprenant K. A., Georg G. I., Himes R. H., Epothilone and paclitaxel: unexpected differences in promoting the assembly and stabilization of yeast microtubules Biochemistry 2002 41 12 3870 3874 (Pubitemid 34251025)
    • (2002) Biochemistry , vol.41 , Issue.12 , pp. 3870-3874
    • Bode, C.J.1    Gupta Jr., M.L.2    Reiff, E.A.3    Suprenant, K.A.4    Georg, G.I.5    Himes, R.H.6
  • 27
  • 31
    • 77953025896 scopus 로고    scopus 로고
    • Efficacy of ixabepilone in ER/PR/HER2-negative (triple-negative) breast cancer
    • Perez E. A., Patel T., Moreno-Aspitia A., Efficacy of ixabepilone in ER/PR/HER2-negative (triple-negative) breast cancer Breast Cancer Research and Treatment 2010 121 2 261 271
    • (2010) Breast Cancer Research and Treatment , vol.121 , Issue.2 , pp. 261-271
    • Perez, E.A.1    Patel, T.2    Moreno-Aspitia, A.3
  • 33
    • 58749113261 scopus 로고    scopus 로고
    • Clinical development of ixabepilone and other epothilones in patients with advanced solid tumors
    • Rivera E., Lee J., Davies A., Clinical development of ixabepilone and other epothilones in patients with advanced solid tumors Oncologist 2008 13 12 1207 1223
    • (2008) Oncologist , vol.13 , Issue.12 , pp. 1207-1223
    • Rivera, E.1    Lee, J.2    Davies, A.3
  • 34
    • 3042701597 scopus 로고    scopus 로고
    • Epothilones: Mechanism of action and biologic activity
    • DOI 10.1200/JCO.2004.12.001
    • Goodin S., Kane M. P., Rubin E. H., Epothilones: mechanism of action and biologic activity Journal of Clinical Oncology 2004 22 10 2015 2025 (Pubitemid 41095195)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.10 , pp. 2015-2025
    • Goodin, S.1    Kane, M.P.2    Rubin, E.H.3
  • 35
    • 84862289134 scopus 로고    scopus 로고
    • Ixempra PI, IXEMPRA Kit (ixabepilone) for Injection, Full Prescribing Information, Bristol-Myers Squibb, 2010
    • Ixempra PI, IXEMPRA Kit (ixabepilone) for Injection, Full Prescribing Information, Bristol-Myers Squibb, 2010
  • 36
    • 34548157209 scopus 로고    scopus 로고
    • Efficacy and safety of ixabepilone (BMS-247550) in a phase II study of patients with advanced breast cancer resistant to an anthracycline, a taxane, and capecitabine
    • DOI 10.1200/JCO.2006.09.3849
    • Perez E. A., Lerzo G., Pivot X., Thomas E., Vahdat L., Bosserman L., Viens P., Cai C., Mullaney B., Peck R., Hortobagyi G. N., Efficacy and safety of ixabepilone (BMS-247550) in a phase II study of patients with advanced breast cancer resistant to an anthracycline, a taxane, and capecitabine Journal of Clinical Oncology 2007 25 23 3407 3414 (Pubitemid 47310876)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.23 , pp. 3407-3414
    • Perez, E.A.1    Lerzo, G.2    Pivot, X.3    Thomas, E.4    Vahdat, L.5    Bosserman, L.6    Viens, P.7    Cai, C.8    Mullaney, B.9    Peck, R.10    Hortobagyi, G.N.11
  • 39
    • 84856356334 scopus 로고    scopus 로고
    • Ixabepilone plus capecitabine in advanced breast cancer patients with early relapse after adjuvant anthracyclines and taxanes: A pooled subset analysis of two phase III studies
    • Jassem J., Fein L., Karwal M., Campone M., Peck R., Poulart V., Vahdat L., Ixabepilone plus capecitabine in advanced breast cancer patients with early relapse after adjuvant anthracyclines and taxanes: a pooled subset analysis of two phase III studies Breast 2012 21 1 89 94
    • (2012) Breast , vol.21 , Issue.1 , pp. 89-94
    • Jassem, J.1    Fein, L.2    Karwal, M.3    Campone, M.4    Peck, R.5    Poulart, V.6    Vahdat, L.7
  • 41
    • 79952836195 scopus 로고    scopus 로고
    • Randomized phase II study of weekly versus every-3-week ixabepilone plus bevacizumab (ixa/bev) versus paclitaxel plus bevacizumab (pac/bev) as first-line therapy for metastatic breast cancer (MBC): Final results
    • Rugo H. S., Campone M., Amadori D., Randomized phase II study of weekly versus every-3-week ixabepilone plus bevacizumab (ixa/bev) versus paclitaxel plus bevacizumab (pac/bev) as first-line therapy for metastatic breast cancer (MBC): final results Journal of Clinical Oncology 2010 28 15s 1040
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.15 S , pp. 1040
    • Rugo, H.S.1    Campone, M.2    Amadori, D.3
  • 44
    • 74849122823 scopus 로고    scopus 로고
    • A phase II trial of trastuzumab plus weekly ixabepilone and carboplatin in patients with HER2-positive metastatic breast cancer: An Eastern Cooperative Oncology Group Trial
    • Moulder S., Li H., Wang M., Gradishar W. J., Perez E. A., Sparano J. A., Pins M., Yang X., Sledge G. W., A phase II trial of trastuzumab plus weekly ixabepilone and carboplatin in patients with HER2-positive metastatic breast cancer: an Eastern Cooperative Oncology Group Trial Breast Cancer Research and Treatment 2010 119 3 663 671
    • (2010) Breast Cancer Research and Treatment , vol.119 , Issue.3 , pp. 663-671
    • Moulder, S.1    Li, H.2    Wang, M.3    Gradishar, W.J.4    Perez, E.A.5    Sparano, J.A.6    Pins, M.7    Yang, X.8    Sledge, G.W.9
  • 47
    • 58249142470 scopus 로고    scopus 로고
    • Phase i dose escalation study of weekly ixabepilone, an epothilone analog, in patients with advanced solid tumors who have failed standard therapy
    • Awada A., Piccart M. J., Jones S. F., Peck R. A., Gil T., Lebwohl D., Wu C. Y., Burris H. A., Phase i dose escalation study of weekly ixabepilone, an epothilone analog, in patients with advanced solid tumors who have failed standard therapy Cancer Chemotherapy and Pharmacology 2009 63 3 417 425
    • (2009) Cancer Chemotherapy and Pharmacology , vol.63 , Issue.3 , pp. 417-425
    • Awada, A.1    Piccart, M.J.2    Jones, S.F.3    Peck, R.A.4    Gil, T.5    Lebwohl, D.6    Wu, C.Y.7    Burris, H.A.8
  • 48
    • 34548169630 scopus 로고    scopus 로고
    • Phase II trial of ixabepilone, an epothilone B analog, in patients with metastatic breast cancer previously untreated with taxanes
    • DOI 10.1200/JCO.2006.10.0784
    • Denduluri N., Low J. A., Lee J. J., Berman A. W., Walshe J. M., Vatas U., Chow C. K., Steinberg S. M., Yang S. X., Swain S. M., Phase II trial of ixabepilone, an epothilone B analog, in patients with metastatic breast cancer previously untreated with taxanes Journal of Clinical Oncology 2007 25 23 3421 3427 (Pubitemid 47310878)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.23 , pp. 3421-3427
    • Denduluri, N.1    Low, J.A.2    Lee, J.J.3    Berman, A.W.4    Walshe, J.M.5    Vatas, U.6    Chow, C.K.7    Steinberg, S.M.8    Yang, S.X.9    Swain, S.M.10
  • 50
    • 34548179878 scopus 로고    scopus 로고
    • Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, as first-line therapy in patients with metastatic breast cancer previously treated with anthracycline chemotherapy
    • DOI 10.1200/JCO.2006.09.7535
    • Roché H., Yelle L., Cognetti F., Mauriac L., Bunnell C., Sparano J., Kerbrat P., Delord J. P., Vahdat L., Peck R., Lebwohl D., Ezzeddine R., Curé H., Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, as first-line therapy in patients with metastatic breast cancer previously treated with anthracycline chemotherapy Journal of Clinical Oncology 2007 25 23 3415 3420 (Pubitemid 47310877)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.23 , pp. 3415-3420
    • Roche, H.1    Yelle, L.2    Cognetti, F.3    Mauriac, L.4    Bunnell, C.5    Sparano, J.6    Kerbrat, P.7    Delord, J.-P.8    Vahdat, L.9    Peck, R.10    Lebwohl, D.11    Ezzeddine, R.12    Cure, H.13
  • 53
    • 79952144443 scopus 로고    scopus 로고
    • A phase II study of ixabepilone plus trastuzumab for metastatic HER2-positive breast cancer
    • 693137
    • Tolaney S. M., Najita J., Chen W., A phase II study of ixabepilone plus trastuzumab for metastatic HER2-positive breast cancer Cancer Research 2009 69, abstract 3137
    • (2009) Cancer Research
    • Tolaney, S.M.1    Najita, J.2    Chen, W.3
  • 56
    • 34447319255 scopus 로고    scopus 로고
    • Capecitabine: Expanding options for the treatment of patients with early or locally advanced breast cancer
    • Wardley A., Capecitabine: expanding options for the treatment of patients with early or locally advanced breast cancer Oncologist 2006 11 1 20 26
    • (2006) Oncologist , vol.11 , Issue.1 , pp. 20-26
    • Wardley, A.1
  • 57
    • 0035751675 scopus 로고    scopus 로고
    • Preoperative chemotherapy in patients with operable breast cancer: Nine-year results from National Surgical Adjuvant Breast and Bowel Project B-18
    • Wolmark N., Wang J., Mamounas E., Bryant J., Fisher B., Preoperative chemotherapy in patients with operable breast cancer: nine-year results from National Surgical Adjuvant Breast and Bowel Project B-18 Journal of the National Cancer Institute Monographs 2001 30 96 102
    • (2001) Journal of the National Cancer Institute Monographs , Issue.30 , pp. 96-102
    • Wolmark, N.1    Wang, J.2    Mamounas, E.3    Bryant, J.4    Fisher, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.