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Volumn 33, Issue 7, 2014, Pages 882-890

RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model

Author keywords

cofilin; cytoskeleton; orthotopic xenograft; tubulin

Indexed keywords

ACTIN DEPOLYMERIZING FACTORS; ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; CYTOSKELETON; GENE KNOCKDOWN TECHNIQUES; HUMANS; LUNG NEOPLASMS; MICE; NEOPLASM INVASIVENESS; NEOPLASM TRANSPLANTATION; NEUROBLASTOMA; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RHO-ASSOCIATED KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; STATHMIN; TUMOR BURDEN;

EID: 84894064647     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.11     Document Type: Article
Times cited : (55)

References (40)
  • 2
    • 33846051928 scopus 로고    scopus 로고
    • Mechanisms of invasion and metastasis in human neuroblastoma
    • Ara T, DeClerck YA. Mechanisms of invasion and metastasis in human neuroblastoma. Cancer Metastasis Rev 2006; 25: 645-657.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 645-657
    • Ara, T.1    Declerck, Y.A.2
  • 4
    • 52249098003 scopus 로고    scopus 로고
    • Lung metastases in neuroblastoma at initial diagnosis: A report from the International Neuroblastoma Risk Group (INRG) project
    • DuBois SG, London WB, Zhang Y, Matthay KK, Monclair T, Ambros PF et al. Lung metastases in neuroblastoma at initial diagnosis: a report from the International Neuroblastoma Risk Group (INRG) project. Pediatr Blood Cancer 2008; 51: 589-592.
    • (2008) Pediatr Blood Cancer , vol.51 , pp. 589-592
    • Dubois, S.G.1    London, W.B.2    Zhang, Y.3    Matthay, K.K.4    Monclair, T.5    Ambros, P.F.6
  • 5
    • 70249116807 scopus 로고    scopus 로고
    • Actin dynamics at the leading edge: From simple machinery to complex networks
    • Insall RH, Machesky LM. Actin dynamics at the leading edge: from simple machinery to complex networks. Dev Cell 2009; 17: 310-322.
    • (2009) Dev Cell , vol.17 , pp. 310-322
    • Insall, R.H.1    MacHesky, L.M.2
  • 6
    • 33750289641 scopus 로고    scopus 로고
    • ROCK signaling mediates the adoption of different modes of migration and invasion in human mammary epithelial tumor cells
    • Torka R, Thuma F, Herzog V, Kirfel G. ROCK signaling mediates the adoption of different modes of migration and invasion in human mammary epithelial tumor cells. Exp Cell Res 2006; 312: 3857-3871.
    • (2006) Exp Cell Res , vol.312 , pp. 3857-3871
    • Torka, R.1    Thuma, F.2    Herzog, V.3    Kirfel, G.4
  • 7
    • 79961133708 scopus 로고    scopus 로고
    • Microtubule remodelling is required for the front-rear polarity switch during contact inhibition of locomotion
    • Kadir S, Astin JW, Tahtamouni L, Martin P, Nobes CD. Microtubule remodelling is required for the front-rear polarity switch during contact inhibition of locomotion. J Cell Sci 2011; 124: 2642-2653.
    • (2011) J Cell Sci , vol.124 , pp. 2642-2653
    • Kadir, S.1    Astin, J.W.2    Tahtamouni, L.3    Martin, P.4    Nobes, C.D.5
  • 8
    • 0032751977 scopus 로고    scopus 로고
    • Stathmin and its phosphoprotein family: General properties, biochemical and functional interaction with tubulin
    • Curmi PA, Gavet O, Charbaut E, Ozon S, Lachkar-Colmerauer S, Manceau V et al. Stathmin and its phosphoprotein family: general properties, biochemical and functional interaction with tubulin. Cell Struct Funct 1999; 24: 345-357.
    • (1999) Cell Struct Funct , vol.24 , pp. 345-357
    • Curmi, P.A.1    Gavet, O.2    Charbaut, E.3    Ozon, S.4    Lachkar-Colmerauer, S.5    Manceau, V.6
  • 10
    • 77953049436 scopus 로고    scopus 로고
    • Stathmin1 overexpression associated with polyploidy, tumor-cell invasion, early recurrence, and poor prognosis in human hepatoma
    • Hsieh SY, Huang SF, Yu MC, Yeh TS, Chen TC, Lin YJ et al. Stathmin1 overexpression associated with polyploidy, tumor-cell invasion, early recurrence, and poor prognosis in human hepatoma. Mol Carcinog 2010; 49: 476-487.
    • (2010) Mol Carcinog , vol.49 , pp. 476-487
    • Hsieh, S.Y.1    Huang, S.F.2    Yu, M.C.3    Yeh, T.S.4    Chen, T.C.5    Lin, Y.J.6
  • 11
    • 76949108807 scopus 로고    scopus 로고
    • Overexpression of stathmin1 in the diffuse type of gastric cancer and its roles in proliferation and migration of gastric cancer cells
    • Jeon TY, Han ME, Lee YW, Lee YS, Kim GH, Song GA et al. Overexpression of stathmin1 in the diffuse type of gastric cancer and its roles in proliferation and migration of gastric cancer cells. Br J Cancer 2010; 102: 710-718.
    • (2010) Br J Cancer , vol.102 , pp. 710-718
    • Jeon, T.Y.1    Han, M.E.2    Lee, Y.W.3    Lee, Y.S.4    Kim, G.H.5    Song, G.A.6
  • 12
    • 34250687198 scopus 로고    scopus 로고
    • Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity
    • Saal LH, Johansson P, Holm K, Gruvberger-Saal SK, She QB, Maurer M et al. Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity. Proc Natl Acad Sci USA 2007; 104: 7564-7569.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 7564-7569
    • Saal, L.H.1    Johansson, P.2    Holm, K.3    Gruvberger-Saal, S.K.4    She, Q.B.5    Maurer, M.6
  • 13
    • 79956000555 scopus 로고    scopus 로고
    • Stathmin overexpression identifies high-risk patients and lymph node metastasis in endometrial cancer
    • Trovik J, Wik E, Stefansson IM, Marcickiewicz J, Tingulstad S, Staff AC et al. Stathmin overexpression identifies high-risk patients and lymph node metastasis in endometrial cancer. Clin Cancer Res 2011; 17: 3368-3377.
    • (2011) Clin Cancer Res , vol.17 , pp. 3368-3377
    • Trovik, J.1    Wik, E.2    Stefansson, I.M.3    Marcickiewicz, J.4    Tingulstad, S.5    Staff, A.C.6
  • 14
    • 55249097171 scopus 로고    scopus 로고
    • Stathmin expression in pheochromocytomas, paragangliomas, and in other endocrine tumors
    • Sadow PM, Rumilla KM, Erickson LA, Lloyd RV. Stathmin expression in pheochromocytomas, paragangliomas, and in other endocrine tumors. Endocr Pathol 2008; 19: 97-103.
    • (2008) Endocr Pathol , vol.19 , pp. 97-103
    • Sadow, P.M.1    Rumilla, K.M.2    Erickson, L.A.3    Lloyd, R.V.4
  • 15
    • 0025223706 scopus 로고
    • N-myc gene amplification in neuroblastoma is associated with altered phosphorylation of a proliferation related polypeptide (Op18)
    • Hailat N, Strahler J, Melhem R, Zhu XX, Brodeur G, Seeger RC et al. N-myc gene amplification in neuroblastoma is associated with altered phosphorylation of a proliferation related polypeptide (Op18). Oncogene 1990; 5: 1615-1618.
    • (1990) Oncogene , vol.5 , pp. 1615-1618
    • Hailat, N.1    Strahler, J.2    Melhem, R.3    Zhu, X.X.4    Brodeur, G.5    Seeger, R.C.6
  • 17
    • 4644335095 scopus 로고    scopus 로고
    • Neuronal-associated microtubule proteins class III beta-tubulin and MAP2c in neuroblastoma: Role in resistance to microtubule-targeted drugs
    • Don S, Verrills NM, Liaw TY, Liu ML, Norris MD, Haber M et al. Neuronal-associated microtubule proteins class III beta-tubulin and MAP2c in neuroblastoma: role in resistance to microtubule-targeted drugs. Mol Cancer Ther 2004; 3: 1137-1146.
    • (2004) Mol Cancer Ther , vol.3 , pp. 1137-1146
    • Don, S.1    Verrills, N.M.2    Liaw, T.Y.3    Liu, M.L.4    Norris, M.D.5    Haber, M.6
  • 18
    • 34247468876 scopus 로고    scopus 로고
    • Regulation of the actin cytoskeleton in cancer cell migration and invasion
    • Yamaguchi H, Condeelis J. Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim Biophys Acta 2007; 1773: 642-652.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 642-652
    • Yamaguchi, H.1    Condeelis, J.2
  • 19
    • 24944513184 scopus 로고    scopus 로고
    • Role of Rho, Rac, and Rho-kinase in phosphorylation of myosin light chain, development of polarity, and spontaneous migration of Walker 256 carcinosarcoma cells
    • Gutjahr MC, Rossy J, Niggli V. Role of Rho, Rac, and Rho-kinase in phosphorylation of myosin light chain, development of polarity, and spontaneous migration of Walker 256 carcinosarcoma cells. Exp Cell Res 2005; 308: 422-438.
    • (2005) Exp Cell Res , vol.308 , pp. 422-438
    • Gutjahr, M.C.1    Rossy, J.2    Niggli, V.3
  • 20
    • 0033772834 scopus 로고    scopus 로고
    • Use and properties of ROCK-specific inhibitor Y-27632
    • Narumiya S, Ishizaki T, Uehata M. Use and properties of ROCK-specific inhibitor Y-27632. Methods Enzymol 2000; 325: 273-284.
    • (2000) Methods Enzymol , vol.325 , pp. 273-284
    • Narumiya, S.1    Ishizaki, T.2    Uehata, M.3
  • 22
    • 63849308483 scopus 로고    scopus 로고
    • Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation
    • Salvesen HB, Carter SL, Mannelqvist M, Dutt A, Getz G, Stefansson IM et al. Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation. Proc Natl Acad Sci USA 2009; 106: 4834-4839.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 4834-4839
    • Salvesen, H.B.1    Carter, S.L.2    Mannelqvist, M.3    Dutt, A.4    Getz, G.5    Stefansson, I.M.6
  • 23
    • 65549110895 scopus 로고    scopus 로고
    • Coordinated expression of stathmin family members by far upstream sequence elementbinding protein-1 increases motility in non-small cell lung cancer
    • Singer S, Malz M, Herpel E, Warth A, Bissinger M, Keith M et al. Coordinated expression of stathmin family members by far upstream sequence elementbinding protein-1 increases motility in non-small cell lung cancer. Cancer Res 2009; 69: 2234-2243.
    • (2009) Cancer Res , vol.69 , pp. 2234-2243
    • Singer, S.1    Malz, M.2    Herpel, E.3    Warth, A.4    Bissinger, M.5    Keith, M.6
  • 24
    • 33746884331 scopus 로고    scopus 로고
    • Stathmin overexpression cooperates with p53 mutation and osteopontin overexpression, and is associated with tumour progression, early recurrence, and poor prognosis in hepatocellular carcinoma
    • Yuan RH, Jeng YM, Chen HL, Lai PL, Pan HW, Hsieh FJ et al. Stathmin overexpression cooperates with p53 mutation and osteopontin overexpression, and is associated with tumour progression, early recurrence, and poor prognosis in hepatocellular carcinoma. J Pathol 2006; 209: 549-558.
    • (2006) J Pathol , vol.209 , pp. 549-558
    • Yuan, R.H.1    Jeng, Y.M.2    Chen, H.L.3    Lai, P.L.4    Pan, H.W.5    Hsieh, F.J.6
  • 25
    • 77957732541 scopus 로고    scopus 로고
    • LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells
    • Scott RW, Hooper S, Crighton D, Li A, Konig I, Munro J et al. LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells. J Cell Biol 2010; 191: 169-185.
    • (2010) J Cell Biol , vol.191 , pp. 169-185
    • Scott, R.W.1    Hooper, S.2    Crighton, D.3    Li, A.4    Konig, I.5    Munro, J.6
  • 26
    • 34249315804 scopus 로고    scopus 로고
    • Lim kinases regulators of actin dynamics
    • Bernard O. Lim kinases, regulators of actin dynamics. Int J Biochem Cell Biol 2007; 39: 1071-1076.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 1071-1076
    • Bernard, O.1
  • 27
    • 79957784767 scopus 로고    scopus 로고
    • Characterization and detection of cellular and proteomic alterations in stable stathmin-overexpressing, taxol-resistant BT549 breast cancer cells using offgel IEF/PAGE difference gel electrophoresis
    • Balasubramani M, Nakao C, Uechi GT, Cardamone J, Kamath K, Leslie KL et al. Characterization and detection of cellular and proteomic alterations in stable stathmin-overexpressing, taxol-resistant BT549 breast cancer cells using offgel IEF/PAGE difference gel electrophoresis. Mutat Res 2011; 722: 154-164.
    • (2011) Mutat Res , vol.722 , pp. 154-164
    • Balasubramani, M.1    Nakao, C.2    Uechi, G.T.3    Cardamone, J.4    Kamath, K.5    Leslie, K.L.6
  • 28
    • 77950676582 scopus 로고    scopus 로고
    • Lovat F et al. P27kip1 controls cell morphology and motility by regulating microtubule-dependent lipid raft recycling
    • Belletti B, Pellizzari I, Berton S, Fabris L, Wolf K, Lovat F et al. p27kip1 controls cell morphology and motility by regulating microtubule- dependent lipid raft recycling. Mol Cell Biol 2010; 30: 2229-2240.
    • (2010) Mol Cell Biol , vol.30 , pp. 2229-2240
    • Belletti, B.1    Pellizzari, I.2    Berton, S.3    Fabris, L.4    Wolf, K.5
  • 30
    • 0035178210 scopus 로고    scopus 로고
    • Cell motility: Can Rho GTPases and microtubules point the way?
    • Wittmann T, Waterman-Storer CM. Cell motility: can Rho GTPases and microtubules point the way? J Cell Sci 2001; 114: 3795-3803.
    • (2001) J Cell Sci , vol.114 , pp. 3795-3803
    • Wittmann, T.1    Waterman-Storer, C.M.2
  • 31
    • 60549098791 scopus 로고    scopus 로고
    • Membrane transport of WAVE2 and lamellipodia formation require Pak1 that mediates phosphorylation and recruitment of stathmin/Op18 to Pak1-WAVE2-kinesin complex
    • Takahashi K, Suzuki K. Membrane transport of WAVE2 and lamellipodia formation require Pak1 that mediates phosphorylation and recruitment of stathmin/Op18 to Pak1-WAVE2-kinesin complex. Cell Signal 2009; 21: 695-703.
    • (2009) Cell Signal , vol.21 , pp. 695-703
    • Takahashi, K.1    Suzuki, K.2
  • 32
    • 71349086233 scopus 로고    scopus 로고
    • Directional control of WAVE2 membrane targeting by EB1 and phosphatidylinositol 3,4,5-triphosphate
    • Takahashi K, Tanaka T, Suzuki K. Directional control of WAVE2 membrane targeting by EB1 and phosphatidylinositol 3,4,5-triphosphate. Cell Signal 2010; 22: 510-518.
    • (2010) Cell Signal , vol.22 , pp. 510-518
    • Takahashi, K.1    Tanaka, T.2    Suzuki, K.3
  • 33
    • 77952902430 scopus 로고    scopus 로고
    • Mechanisms of motility in metastasizing cells
    • Yilmaz M, Christofori G. Mechanisms of motility in metastasizing cells. Mol Cancer Res 2010; 8: 629-642.
    • (2010) Mol Cancer Res , vol.8 , pp. 629-642
    • Yilmaz, M.1    Christofori, G.2
  • 35
    • 48249090131 scopus 로고    scopus 로고
    • Generation and characterization of novel local and metastatic human neuroblastoma variants
    • Nevo I, Sagi-Assif O, Edry Botzer L, Amar D, Maman S, Kariv N et al. Generation and characterization of novel local and metastatic human neuroblastoma variants. Neoplasia 2008; 10: 816-827.
    • (2008) Neoplasia , vol.10 , pp. 816-827
    • Nevo, I.1    Sagi-Assif, O.2    Edry Botzer, L.3    Amar, D.4    Maman, S.5    Kariv, N.6
  • 36
    • 0035984921 scopus 로고    scopus 로고
    • Biologically relevant orthotopic neuroblastoma xenograft models: Primary adrenal tumor growth and spontaneous distant metastasis
    • Khanna C, Jaboin JJ, Drakos E, Tsokos M, Thiele CJ. Biologically relevant orthotopic neuroblastoma xenograft models: primary adrenal tumor growth and spontaneous distant metastasis. In Vivo 2002; 16: 77-85.
    • (2002) Vivo , vol.16 , pp. 77-85
    • Khanna, C.1    Jaboin, J.J.2    Drakos, E.3    Tsokos, M.4    Thiele, C.J.5
  • 37
    • 12544255526 scopus 로고    scopus 로고
    • A fluorescent orthotopic mouse model for reliable measurement and genetic modulation of human neuroblastoma metastasis
    • Henriksson KC, Almgren MA, Thurlow R, Varki NM, Chang CL. A fluorescent orthotopic mouse model for reliable measurement and genetic modulation of human neuroblastoma metastasis. Clin Exp Metastasis 2004; 21: 563-570.
    • (2004) Clin Exp Metastasis , vol.21 , pp. 563-570
    • Henriksson, K.C.1    Almgren, M.A.2    Thurlow, R.3    Varki, N.M.4    Chang, C.L.5
  • 38
    • 77953750777 scopus 로고    scopus 로고
    • BetaIII-tubulin is a multifunctional protein involved in drug sensitivity and tumorigenesis in non-small cell lung cancer
    • McCarroll JA, Gan PP, Liu M, Kavallaris M. betaIII-tubulin is a multifunctional protein involved in drug sensitivity and tumorigenesis in non-small cell lung cancer. Cancer Res 2010; 70: 4995-5003.
    • (2010) Cancer Res , vol.70 , pp. 4995-5003
    • McCarroll, J.A.1    Gan, P.P.2    Liu, M.3    Kavallaris, M.4
  • 40
    • 2442562277 scopus 로고    scopus 로고
    • A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging
    • Ponomarev V, Doubrovin M, Serganova I, Vider J, Shavrin A, Beresten T et al. A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging. Eur J Nucl Med Mol Imaging 2004; 31: 740-751.
    • (2004) Eur J Nucl Med Mol Imaging , vol.31 , pp. 740-751
    • Ponomarev, V.1    Doubrovin, M.2    Serganova, I.3    Vider, J.4    Shavrin, A.5    Beresten, T.6


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