-
1
-
-
0031710557
-
PAK3 mutation in nonsyndromic X-linked mental retardation
-
Allen K.M., Gleeson J.G., Bagrodia S., Partington M.W., MacMillan J.C., Cerione R.A., Walsh C.A. PAK3 mutation in nonsyndromic X-linked mental retardation. Nat. Genet. 1998, 20:25-30.
-
(1998)
Nat. Genet.
, vol.20
, pp. 25-30
-
-
Allen, K.M.1
Gleeson, J.G.2
Bagrodia, S.3
Partington, M.W.4
MacMillan, J.C.5
Cerione, R.A.6
Walsh, C.A.7
-
3
-
-
84888269144
-
Rac and Cdc42 team up for platelets
-
Aslan J.E., McCarty O.J. Rac and Cdc42 team up for platelets. Blood 2013, 122:3096-3097.
-
(2013)
Blood
, vol.122
, pp. 3096-3097
-
-
Aslan, J.E.1
McCarty, O.J.2
-
4
-
-
0038360854
-
Colocalization of synapsin and actin during synaptic vesicle recycling
-
Bloom O., Evergren E., Tomilin N., Kjaerulff O., Löw P., Brodin L., Pieribone V.A., Greengard P., Shupliakov O. Colocalization of synapsin and actin during synaptic vesicle recycling. J. Cell Biol. 2003, 161:737-747.
-
(2003)
J. Cell Biol.
, vol.161
, pp. 737-747
-
-
Bloom, O.1
Evergren, E.2
Tomilin, N.3
Kjaerulff, O.4
Löw, P.5
Brodin, L.6
Pieribone, V.A.7
Greengard, P.8
Shupliakov, O.9
-
5
-
-
10044235009
-
The mental retardation protein PAK3 contributes to synapse formation and plasticity in hippocampus
-
Boda B., Alberi S., Nikonenko I., Node-Langlois R., Jourdain P., Moosmayer M., Parisi-Jourdain L., Muller D. The mental retardation protein PAK3 contributes to synapse formation and plasticity in hippocampus. J. Neurosci. 2004, 24:10816-10825.
-
(2004)
J. Neurosci.
, vol.24
, pp. 10816-10825
-
-
Boda, B.1
Alberi, S.2
Nikonenko, I.3
Node-Langlois, R.4
Jourdain, P.5
Moosmayer, M.6
Parisi-Jourdain, L.7
Muller, D.8
-
6
-
-
33749043441
-
Central nervous system functions of PAK protein family
-
Boda B., Nikonenko I., Alberi S., Muller D. Central nervous system functions of PAK protein family. Mol. Neurobiol. 2006, 34:67-80.
-
(2006)
Mol. Neurobiol.
, vol.34
, pp. 67-80
-
-
Boda, B.1
Nikonenko, I.2
Alberi, S.3
Muller, D.4
-
7
-
-
51849134561
-
Distinct, but compensatory roles of PAK1 and PAK3 in spine morphogenesis
-
Boda B., Jourdain L., Muller D. Distinct, but compensatory roles of PAK1 and PAK3 in spine morphogenesis. Hippocampus 2008, 18:857-861.
-
(2008)
Hippocampus
, vol.18
, pp. 857-861
-
-
Boda, B.1
Jourdain, L.2
Muller, D.3
-
8
-
-
0038554077
-
Biology of the p21-activated kinases
-
Bokoch G.M. Biology of the p21-activated kinases. Annu. Rev. Biochem. 2003, 72:743-781.
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 743-781
-
-
Bokoch, G.M.1
-
9
-
-
33750924781
-
Regulation of the phagocyte NADPH oxidase by Rac GTPase
-
Bokoch G.M., Zhao T. Regulation of the phagocyte NADPH oxidase by Rac GTPase. Antioxid. Redox Signal. 2006, 8:1533-1548.
-
(2006)
Antioxid. Redox Signal.
, vol.8
, pp. 1533-1548
-
-
Bokoch, G.M.1
Zhao, T.2
-
10
-
-
0031026569
-
P21-activated kinase has substrate specificity similar to Acanthamoeba myosin I heavy chain kinase and activates Acanthamoeba myosin I
-
Brzeska H., Knaus U.G., Wang Z.Y., Bokoch G.M., Korn E.D. P21-activated kinase has substrate specificity similar to Acanthamoeba myosin I heavy chain kinase and activates Acanthamoeba myosin I. Proc. Natl. Acad. Sci. 1997, 94:1092-1095.
-
(1997)
Proc. Natl. Acad. Sci.
, vol.94
, pp. 1092-1095
-
-
Brzeska, H.1
Knaus, U.G.2
Wang, Z.Y.3
Bokoch, G.M.4
Korn, E.D.5
-
11
-
-
38149129457
-
A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function
-
Cahoy J.D., Emery B., Kaushal A., Foo L.C., Zamanian J.L., Christopherson K.S., Yi Xing Y., Lubischer J.L., Krieg P.A., Krupenko S.A., Thompson W.J., Barres B.A. A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J. Neurosci. 2008, 28:264-278.
-
(2008)
J. Neurosci.
, vol.28
, pp. 264-278
-
-
Cahoy, J.D.1
Emery, B.2
Kaushal, A.3
Foo, L.C.4
Zamanian, J.L.5
Christopherson, K.S.6
Yi Xing, Y.7
Lubischer, J.L.8
Krieg, P.A.9
Krupenko, S.A.10
Thompson, W.J.11
Barres, B.A.12
-
12
-
-
84873346887
-
Distinct roles of methamphetamine in modulating spatial memory consolidation, retrieval, reconsolidation and the accompanying changes of ERK and CREB activation in hippocampus and prefrontal cortex
-
Cao G., Zhu J., Zhong Q., Shi C., Dang Y., Han W., Liu X., Xu M., Chen T. Distinct roles of methamphetamine in modulating spatial memory consolidation, retrieval, reconsolidation and the accompanying changes of ERK and CREB activation in hippocampus and prefrontal cortex. Neuropharmacology 2012, 67:144-154.
-
(2012)
Neuropharmacology
, vol.67
, pp. 144-154
-
-
Cao, G.1
Zhu, J.2
Zhong, Q.3
Shi, C.4
Dang, Y.5
Han, W.6
Liu, X.7
Xu, M.8
Chen, T.9
-
13
-
-
0035948287
-
Selective localization of high concentrations of F-actin in subpopulations of dendritic spines in rat central nervous system: a three-dimensional electron microscopic study
-
Capani F., Martone M.E., Deerinck T.J., Ellisman M.H. Selective localization of high concentrations of F-actin in subpopulations of dendritic spines in rat central nervous system: a three-dimensional electron microscopic study. J. Comp. Neurol. 2001, 435:156-170.
-
(2001)
J. Comp. Neurol.
, vol.435
, pp. 156-170
-
-
Capani, F.1
Martone, M.E.2
Deerinck, T.J.3
Ellisman, M.H.4
-
14
-
-
67651089766
-
The p21-activated kinase is required for neuronal migration in the cerebral cortex
-
Causeret F., Terao M., Jacobs T., Nishimura Y.V., Yanagawa Y., Obata K., Hoshino M., Nikolić M. The p21-activated kinase is required for neuronal migration in the cerebral cortex. Cereb. Cortex 2009, 19:861-875.
-
(2009)
Cereb. Cortex
, vol.19
, pp. 861-875
-
-
Causeret, F.1
Terao, M.2
Jacobs, T.3
Nishimura, Y.V.4
Yanagawa, Y.5
Obata, K.6
Hoshino, M.7
Nikolić, M.8
-
15
-
-
0034193426
-
Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338
-
Chaudhary A., King W.G., Mattaliano M.D., Frost J.A., Diaz B., Morrison D.K., Cobb M.H., Marshall M.S., Brugge J.S. Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338. Curr. Biol. 2000, 10:551-554.
-
(2000)
Curr. Biol.
, vol.10
, pp. 551-554
-
-
Chaudhary, A.1
King, W.G.2
Mattaliano, M.D.3
Frost, J.A.4
Diaz, B.5
Morrison, D.K.6
Cobb, M.H.7
Marshall, M.S.8
Brugge, J.S.9
-
16
-
-
77955914539
-
Physiological activation of synaptic Rac>PAK (p-21 activated kinase) signaling is defective in a mouse model of fragile X syndrome
-
Chen L.Y., Rex C.S., Babayan A.H., Krama E.A., Lynch G., Gall C.M., Lauterborn J.C. Physiological activation of synaptic Rac>PAK (p-21 activated kinase) signaling is defective in a mouse model of fragile X syndrome. J. Neurosci. 2010, 30:10977-10984.
-
(2010)
J. Neurosci.
, vol.30
, pp. 10977-10984
-
-
Chen, L.Y.1
Rex, C.S.2
Babayan, A.H.3
Krama, E.A.4
Lynch, G.5
Gall, C.M.6
Lauterborn, J.C.7
-
17
-
-
0032438538
-
Phosphorylation of non-muscle myosin II regulatory light chain by p21-activated kinase (gamma-PAK)
-
Chew T.L., Masaracchia R.A., Goeckeler Z.M., Wysolmerski R.B. Phosphorylation of non-muscle myosin II regulatory light chain by p21-activated kinase (gamma-PAK). J. Muscle Res. Cell Motil. 1998, 19:839-854.
-
(1998)
J. Muscle Res. Cell Motil.
, vol.19
, pp. 839-854
-
-
Chew, T.L.1
Masaracchia, R.A.2
Goeckeler, Z.M.3
Wysolmerski, R.B.4
-
18
-
-
84876004101
-
Roles of Rho GTPases in intracellular transport and cellular transformation
-
Chi X., Wang S., Huang Y., Stamnes M., Chen J.L. Roles of Rho GTPases in intracellular transport and cellular transformation. Int. J. Mol. Sci. 2013, 14:7089-7108.
-
(2013)
Int. J. Mol. Sci.
, vol.14
, pp. 7089-7108
-
-
Chi, X.1
Wang, S.2
Huang, Y.3
Stamnes, M.4
Chen, J.L.5
-
19
-
-
0035907296
-
The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity
-
Chong C., Tan L., Lim L., Manser E. The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity. J. Biol. Chem. 2001, 276:17347-17353.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 17347-17353
-
-
Chong, C.1
Tan, L.2
Lim, L.3
Manser, E.4
-
20
-
-
42349091996
-
Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy
-
Cingolani L.A., Goda Y. Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy. Nat. Rev. Neurosci. 2008, 9:344-356.
-
(2008)
Nat. Rev. Neurosci.
, vol.9
, pp. 344-356
-
-
Cingolani, L.A.1
Goda, Y.2
-
21
-
-
34250188057
-
Dlx transcription factors promote migration through repression of axon and dendrite growth
-
Cobos I., Borello U., Rubenstein J.L. Dlx transcription factors promote migration through repression of axon and dendrite growth. Neuron 2007, 54:873-888.
-
(2007)
Neuron
, vol.54
, pp. 873-888
-
-
Cobos, I.1
Borello, U.2
Rubenstein, J.L.3
-
22
-
-
84881096545
-
Recent advances in the development of p21-activated kinase inhibitors
-
Coleman N., Kissil J. Recent advances in the development of p21-activated kinase inhibitors. Cell Logist. 2012, 2:132-135.
-
(2012)
Cell Logist.
, vol.2
, pp. 132-135
-
-
Coleman, N.1
Kissil, J.2
-
23
-
-
44949176114
-
Pak1 and Pak2 mediate tumor cell invasion through distinct signaling mechanisms
-
Coniglio S.J., Zavarella S., Symons M.H. Pak1 and Pak2 mediate tumor cell invasion through distinct signaling mechanisms. Mol. Cell. Biol. 2008, 28:4162-4172.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 4162-4172
-
-
Coniglio, S.J.1
Zavarella, S.2
Symons, M.H.3
-
24
-
-
41949100602
-
An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase
-
Deacon S.W., Beeser A., Fukui J.A., Rennefahrt U.E., Myers C., Chernoff J., Peterson J.R. An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase. Chem. Biol. 2008, 15:322-331.
-
(2008)
Chem. Biol.
, vol.15
, pp. 322-331
-
-
Deacon, S.W.1
Beeser, A.2
Fukui, J.A.3
Rennefahrt, U.E.4
Myers, C.5
Chernoff, J.6
Peterson, J.R.7
-
25
-
-
84876428563
-
PAK1 protein expression in the auditory cortex of schizophrenia subjects
-
Deo A.J., Goldszer I.M., Li S., DiBitetto J.V., Henteleff R., Sampson A., Lewis D.A., Penzes P., Sweet R.A. PAK1 protein expression in the auditory cortex of schizophrenia subjects. PLoS ONE 2013, 8:e59458.
-
(2013)
PLoS ONE
, vol.8
, pp. e59458
-
-
Deo, A.J.1
Goldszer, I.M.2
Li, S.3
DiBitetto, J.V.4
Henteleff, R.5
Sampson, A.6
Lewis, D.A.7
Penzes, P.8
Sweet, R.A.9
-
26
-
-
36949016215
-
Alzheimer disease models and human neuropathology: similarities and differences
-
Duyckaerts C., Potier M.C., Delatour B. Alzheimer disease models and human neuropathology: similarities and differences. Acta Neuropathol. 2008, 115:5-38.
-
(2008)
Acta Neuropathol.
, vol.115
, pp. 5-38
-
-
Duyckaerts, C.1
Potier, M.C.2
Delatour, B.3
-
27
-
-
33747152561
-
Matrix elasticity directs stem cell lineage specification
-
Engler A.J., Sen S., Sweeney H.L., Discher D.E. Matrix elasticity directs stem cell lineage specification. Cell 2006, 126:677-689.
-
(2006)
Cell
, vol.126
, pp. 677-689
-
-
Engler, A.J.1
Sen, S.2
Sweeney, H.L.3
Discher, D.E.4
-
28
-
-
0033194037
-
Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signaling to actin cytoskeletal dynamics
-
Edwards D.C., Sanders L.C., Bokoch G.M., Gill G.N. Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signaling to actin cytoskeletal dynamics. Nat. Cell Biol. 1999, 1:253-259.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 253-259
-
-
Edwards, D.C.1
Sanders, L.C.2
Bokoch, G.M.3
Gill, G.N.4
-
29
-
-
84863968373
-
Molecular pathways: targeting p21-activated kinase 1 signaling in cancer-opportunities, challenges, and limitations
-
Eswaran J., Li D.Q., Shah A., Kumar R. Molecular pathways: targeting p21-activated kinase 1 signaling in cancer-opportunities, challenges, and limitations. Clin. Cancer Res. 2012, 18:3743-3749.
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 3743-3749
-
-
Eswaran, J.1
Li, D.Q.2
Shah, A.3
Kumar, R.4
-
30
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville S., Hall A. Rho GTPases in cell biology. Nature 2002, 420:629-635.
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
31
-
-
2342432240
-
Cdc42-the centre of polarity
-
Etienne-Manneville S. Cdc42-the centre of polarity. J. Cell Sci. 2004, 117:1291-1300.
-
(2004)
J. Cell Sci.
, vol.117
, pp. 1291-1300
-
-
Etienne-Manneville, S.1
-
32
-
-
0036082812
-
Dendritic spine pathology: cause or consequence of neurological disorders?
-
Fiala J.C., Spacek J., Harris K.M. Dendritic spine pathology: cause or consequence of neurological disorders?. Brain Res. Brain Res. Rev. 2002, 39:29-54.
-
(2002)
Brain Res. Brain Res. Rev.
, vol.39
, pp. 29-54
-
-
Fiala, J.C.1
Spacek, J.2
Harris, K.M.3
-
33
-
-
84884477715
-
The PAKs come of age Celebrating 18 years of Discovery
-
Field J., Manser E. The PAKs come of age Celebrating 18 years of Discovery. Cell. Logistics 2012, 2:54-58.
-
(2012)
Cell. Logistics
, vol.2
, pp. 54-58
-
-
Field, J.1
Manser, E.2
-
34
-
-
0030830220
-
Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins
-
Frost J.A., Steen H., Shapiro P., Lewis T., Ahn N., Shaw P.E., Cobb M.H. Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins. EMBO J. 1997, 16:6426-6438.
-
(1997)
EMBO J.
, vol.16
, pp. 6426-6438
-
-
Frost, J.A.1
Steen, H.2
Shapiro, P.3
Lewis, T.4
Ahn, N.5
Shaw, P.E.6
Cobb, M.H.7
-
35
-
-
0029830139
-
The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1
-
Galisteo M.L., Chernoff J., Su Y.C., Skolnik E.Y., Schlessinger The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1. J. Biol. Chem. 1996, 271:20997-21000.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20997-21000
-
-
Galisteo, M.L.1
Chernoff, J.2
Su, Y.C.3
Skolnik, E.Y.4
Schlessinger, J.5
-
36
-
-
0034674408
-
Phosphorylation of myosin light chain kinase by p21-activated kinase PAK2
-
Goeckeler Z.M., Masaracchia R.A., Zeng Q., Chew T.L., Gallagher P., Wysolmerski R.B. Phosphorylation of myosin light chain kinase by p21-activated kinase PAK2. J. Biol. Chem. 2000, 275:18366-18374.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18366-18374
-
-
Goeckeler, Z.M.1
Masaracchia, R.A.2
Zeng, Q.3
Chew, T.L.4
Gallagher, P.5
Wysolmerski, R.B.6
-
37
-
-
33746892681
-
Hippocampal pyramidal cells in adult Fmr1 knockout mice exhibit an immature appearing profile of dendritic spines
-
Grossman A.W., Elisseou N.M., McKinney B.C., Greenough W.T. Hippocampal pyramidal cells in adult Fmr1 knockout mice exhibit an immature appearing profile of dendritic spines. Brain Res. 2006, 1084:158-164.
-
(2006)
Brain Res.
, vol.1084
, pp. 158-164
-
-
Grossman, A.W.1
Elisseou, N.M.2
McKinney, B.C.3
Greenough, W.T.4
-
38
-
-
77956619092
-
Developmental characteristics of dendritic spines in the dentate gyrus of Fmr1 knockout mice
-
Grossman A.W., Aldridge G.M., Lee K.J., Zeman M.K., Azam H.S., Arii T., Imoto K., Greenough W.T., Rhyu I.J. Developmental characteristics of dendritic spines in the dentate gyrus of Fmr1 knockout mice. Brain Res. 2010, 1355:221-227.
-
(2010)
Brain Res.
, vol.1355
, pp. 221-227
-
-
Grossman, A.W.1
Aldridge, G.M.2
Lee, K.J.3
Zeman, M.K.4
Azam, H.S.5
Arii, T.6
Imoto, K.7
Greenough, W.T.8
Rhyu, I.J.9
-
39
-
-
0036384295
-
Pak1 is involved in dendrite initiation as a downstream effector of Rac1 in cortical neurons
-
Hayashi K., Ohshima T., Mikoshiba K. Pak1 is involved in dendrite initiation as a downstream effector of Rac1 in cortical neurons. Mol. Cell. Neurosci. 2002, 20:579-594.
-
(2002)
Mol. Cell. Neurosci.
, vol.20
, pp. 579-594
-
-
Hayashi, K.1
Ohshima, T.2
Mikoshiba, K.3
-
40
-
-
2942583823
-
Altered cortical synaptic morphology and impaired memory consolidation in forebrain-specific dominant-negative PAK transgenic mice
-
Hayashi M.L., Choi S.Y., Rao B.S., Jung H.Y., Lee H.K., Zhang D., Sumantra Chattarji S., Kirkwood A., Tonegawa S. Altered cortical synaptic morphology and impaired memory consolidation in forebrain-specific dominant-negative PAK transgenic mice. Neuron 2004, 42:773-787.
-
(2004)
Neuron
, vol.42
, pp. 773-787
-
-
Hayashi, M.L.1
Choi, S.Y.2
Rao, B.S.3
Jung, H.Y.4
Lee, H.K.5
Zhang, D.6
Sumantra Chattarji, S.7
Kirkwood, A.8
Tonegawa, S.9
-
41
-
-
80054026722
-
Principles of unconventional myosin function and targeting
-
Hartman M.A., Finan D., Sivaramakrishnan S., Spudich J.A. Principles of unconventional myosin function and targeting. Annu. Rev. Cell Dev. Biol. 2011, 27:133-135.
-
(2011)
Annu. Rev. Cell Dev. Biol.
, vol.27
, pp. 133-135
-
-
Hartman, M.A.1
Finan, D.2
Sivaramakrishnan, S.3
Spudich, J.A.4
-
42
-
-
0024595352
-
The cytoskeletal architecture of the presynaptic terminal and molecular structure of synapsin 1
-
Hirokawa N., Sobue K., Kanda K., Harada A., Yorifuji H. The cytoskeletal architecture of the presynaptic terminal and molecular structure of synapsin 1. J. Cell Biol. 1989, 108:111-126.
-
(1989)
J. Cell Biol.
, vol.108
, pp. 111-126
-
-
Hirokawa, N.1
Sobue, K.2
Kanda, K.3
Harada, A.4
Yorifuji, H.5
-
43
-
-
77952334420
-
Actin in dendritic spines: connecting dynamics to function
-
Hotulainen P., Hoogenraad C.C. Actin in dendritic spines: connecting dynamics to function. J. Cell Biol. 2010, 189:619-629.
-
(2010)
J. Cell Biol.
, vol.189
, pp. 619-629
-
-
Hotulainen, P.1
Hoogenraad, C.C.2
-
45
-
-
78751518773
-
P21-activated kinases 1 and 3 control brain size through coordinating neuronal complexity and synaptic properties
-
Huang W., Zhou Z., Asrar S., Henkelman M., Xie W., Jia Z. P21-activated kinases 1 and 3 control brain size through coordinating neuronal complexity and synaptic properties. Mol. Cell. Biol. 2011, 31:388-403.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 388-403
-
-
Huang, W.1
Zhou, Z.2
Asrar, S.3
Henkelman, M.4
Xie, W.5
Jia, Z.6
-
46
-
-
84872088087
-
Variant of TREM2 associated with the risk of Alzheimer's disease
-
Jonsson T., Stefansson H., Steinberg S., Jonsdottir I., Jonsson P.V., Snaedal J., et al. Variant of TREM2 associated with the risk of Alzheimer's disease. N. Engl. J. Med. 2013, 368:107-116.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 107-116
-
-
Jonsson, T.1
Stefansson, H.2
Steinberg, S.3
Jonsdottir, I.4
Jonsson, P.V.5
Snaedal, J.6
-
47
-
-
84874108407
-
A p21-activated kinase (PAK1) signaling cascade coordi nately regulates F-actin remodeling and insulin granule exocytosis in pancreatic β cells
-
Kalwat M.A., Yoder S.M., Wang Z., Thurmond D.C. A p21-activated kinase (PAK1) signaling cascade coordi nately regulates F-actin remodeling and insulin granule exocytosis in pancreatic β cells. Biochem. Pharmacol. 2013, 85:808-816.
-
(2013)
Biochem. Pharmacol.
, vol.85
, pp. 808-816
-
-
Kalwat, M.A.1
Yoder, S.M.2
Wang, Z.3
Thurmond, D.C.4
-
48
-
-
77949273382
-
Structural dynamics of dendritic spines in memory and cognition
-
Kasai H., Fukuda M., Watanabe S., Hayashi- Takagi A., Noguchi J. Structural dynamics of dendritic spines in memory and cognition. Trends Neurosci. 2010, 33:121-129.
-
(2010)
Trends Neurosci.
, vol.33
, pp. 121-129
-
-
Kasai, H.1
Fukuda, M.2
Watanabe, S.3
Hayashi-Takagi, A.4
Noguchi, J.5
-
49
-
-
78751565332
-
Getting smart about p21-activated kinases
-
Kelly M.L., Chernoff J. Getting smart about p21-activated kinases. Mol. Cell. Biol. 2011, 31:386-387.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 386-387
-
-
Kelly, M.L.1
Chernoff, J.2
-
50
-
-
84875429547
-
Myosin motors at neuronal synapses: drivers of membrane transport and actin dynamics
-
Kneussel M., Wagner W. Myosin motors at neuronal synapses: drivers of membrane transport and actin dynamics. Nat. Rev. Neurosci. 2013, 14:233-247.
-
(2013)
Nat. Rev. Neurosci.
, vol.14
, pp. 233-247
-
-
Kneussel, M.1
Wagner, W.2
-
51
-
-
75649108232
-
Molecular architecture of synaptic actin cytoskeleton in hippocampal neurons reveals a mechanism of dendritic spine morphogenesis
-
Korobova F., Svitkina T. Molecular architecture of synaptic actin cytoskeleton in hippocampal neurons reveals a mechanism of dendritic spine morphogenesis. Mol. Biol. Cell 2010, 21:165-176.
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 165-176
-
-
Korobova, F.1
Svitkina, T.2
-
52
-
-
0032511882
-
The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338
-
King A.J., Sun H., Diaz B., Barnard D., Miao W., Bagrodia S., Marshall M.S. The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338. Nature 1998, 396:180-183.
-
(1998)
Nature
, vol.396
, pp. 180-183
-
-
King, A.J.1
Sun, H.2
Diaz, B.3
Barnard, D.4
Miao, W.5
Bagrodia, S.6
Marshall, M.S.7
-
53
-
-
0035907051
-
Phosphorylation site specificity of the Pak-mediated regulation of Raf-1 and cooperativity with Src
-
King A.J., Wireman R.S., Hamilton M., Marshall M.S. Phosphorylation site specificity of the Pak-mediated regulation of Raf-1 and cooperativity with Src. FEBS Lett. 2001, 497:6-14.
-
(2001)
FEBS Lett.
, vol.497
, pp. 6-14
-
-
King, A.J.1
Wireman, R.S.2
Hamilton, M.3
Marshall, M.S.4
-
54
-
-
34547133773
-
The p21-activated kinase 3 implicated in mental retardation regulates spine morphogenesis through a Cdc42-dependent pathway
-
Kreis P., Thevenot E., Rousseau V., Boda B., Muller D., Barnier J. The p21-activated kinase 3 implicated in mental retardation regulates spine morphogenesis through a Cdc42-dependent pathway. J. Biol. Chem. 2007, 282:21497-21506.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 21497-21506
-
-
Kreis, P.1
Thevenot, E.2
Rousseau, V.3
Boda, B.4
Muller, D.5
Barnier, J.6
-
55
-
-
48249105489
-
The four mammalian splice variants encoded by the p21-activated kinase 3 gene have different biological properties
-
Kreis P., Rousseau V., Thévenot E., Combeau G., Barnier J.V. The four mammalian splice variants encoded by the p21-activated kinase 3 gene have different biological properties. J. Neurochem. 2008, 106:1184-1197.
-
(2008)
J. Neurochem.
, vol.106
, pp. 1184-1197
-
-
Kreis, P.1
Rousseau, V.2
Thévenot, E.3
Combeau, G.4
Barnier, J.V.5
-
56
-
-
58249128132
-
PAK signalling in neuronal physiology
-
Kreis P., Barnier J.V. PAK signalling in neuronal physiology. Cell. Signal. 2009, 21:384-393.
-
(2009)
Cell. Signal.
, vol.21
, pp. 384-393
-
-
Kreis, P.1
Barnier, J.V.2
-
58
-
-
0347915731
-
Structural plasticity and memory
-
Lamprecht R., LeDoux J. Structural plasticity and memory. Nat. Rev. Neurosci. 2004, 5(1):45-54.
-
(2004)
Nat. Rev. Neurosci.
, vol.5
, Issue.1
, pp. 45-54
-
-
Lamprecht, R.1
LeDoux, J.2
-
59
-
-
0024002576
-
The organization of cytoplasm at the presynaptic active zone of a central nervous system synapse
-
Landis D.M., Hall A.K., Weinstein L.A., Reese T.S. The organization of cytoplasm at the presynaptic active zone of a central nervous system synapse. Neuron 1998, 1:201-209.
-
(1998)
Neuron
, vol.1
, pp. 201-209
-
-
Landis, D.M.1
Hall, A.K.2
Weinstein, L.A.3
Reese, T.S.4
-
60
-
-
0034604338
-
Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch
-
Lei M., Lu W., Meng W., Parrini M.C., Eck M.J., Mayer B.J., Harrison S.C. Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch. Cell 2000, 102:387-397.
-
(2000)
Cell
, vol.102
, pp. 387-397
-
-
Lei, M.1
Lu, W.2
Meng, W.3
Parrini, M.C.4
Eck, M.J.5
Mayer, B.J.6
Harrison, S.C.7
-
61
-
-
0041352963
-
Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42
-
Li Z., Hannigan M., Mo Z., Liu B., Lu W. Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42. Cell 2003, 114:215-227.
-
(2003)
Cell
, vol.114
, pp. 215-227
-
-
Li, Z.1
Hannigan, M.2
Mo, Z.3
Liu, B.4
Lu, W.5
-
62
-
-
40549095312
-
P21-activated kinase 1 promotes soluble mutant huntingtin self-interaction and enhances toxicity
-
Luo S., Mizuta H., Rubinsztein D.C. P21-activated kinase 1 promotes soluble mutant huntingtin self-interaction and enhances toxicity. Hum. Mol. Genet. 2008, 17:895-905.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 895-905
-
-
Luo, S.1
Mizuta, H.2
Rubinsztein, D.C.3
-
63
-
-
46649100113
-
P21-activated kinase-aberrant activation and translocation in Alzheimer disease pathogenesis
-
Ma Q.L., Yang F., Calon F., Ubeda O.J., Hansen J.E., Weisbart R.H., Beech W., Frautschy S.A., Cole G.M. P21-activated kinase-aberrant activation and translocation in Alzheimer disease pathogenesis. J. Biol. Chem. 2008, 283:14132-14143.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 14132-14143
-
-
Ma, Q.L.1
Yang, F.2
Calon, F.3
Ubeda, O.J.4
Hansen, J.E.5
Weisbart, R.H.6
Beech, W.7
Frautschy, S.A.8
Cole, G.M.9
-
64
-
-
84883243907
-
PAK in Alzheimer disease, Huntington disease and X-linked mental retardation
-
Ma Q.-L., Yang F., Frautschy S., Cole G.M. PAK in Alzheimer disease, Huntington disease and X-linked mental retardation. Cell Logist 2012, 2:117-125.
-
(2012)
Cell Logist
, vol.2
, pp. 117-125
-
-
Ma, Q.-L.1
Yang, F.2
Frautschy, S.3
Cole, G.M.4
-
65
-
-
75749128660
-
Filamin and filaminbinding proteins in integrin-regulation and adhesion. Focus on: "FilaminA is required for vimentin-mediated cell adhesion and spreading"
-
C206-8
-
MacPherson M., Fagerholm S.C. Filamin and filaminbinding proteins in integrin-regulation and adhesion. Focus on: "FilaminA is required for vimentin-mediated cell adhesion and spreading". Am. J. Physiol. Cell Physiol. 2010, 298:C206-8.
-
(2010)
Am. J. Physiol. Cell Physiol.
, vol.298
-
-
MacPherson, M.1
Fagerholm, S.C.2
-
66
-
-
0028078824
-
Brain serine/threonine protein kinase activated by Cdc42 and Rac1
-
Manser E., Leung T., Salihuddin H., Zhao Z.S., Lim L. Brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature 1994, 367:40-46.
-
(1994)
Nature
, vol.367
, pp. 40-46
-
-
Manser, E.1
Leung, T.2
Salihuddin, H.3
Zhao, Z.S.4
Lim, L.5
-
67
-
-
0028862297
-
Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family
-
Manser E., Chong C., Zhao Z.S., Leung T., Michael G., Hall C., Lim L. Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family. J. Biol. Chem. 1995, 270:25070-25078.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25070-25078
-
-
Manser, E.1
Chong, C.2
Zhao, Z.S.3
Leung, T.4
Michael, G.5
Hall, C.6
Lim, L.7
-
68
-
-
0031610579
-
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
-
Manser E., Loo T.H., Koh C.G., Zhao Z.S., Chen X.Q., Tan L., Tan I., Leung T., Lim L. PAK kinases are directly coupled to the PIX family of nucleotide exchange factors. Mol. Cell 1998, 1:183-192.
-
(1998)
Mol. Cell
, vol.1
, pp. 183-192
-
-
Manser, E.1
Loo, T.H.2
Koh, C.G.3
Zhao, Z.S.4
Chen, X.Q.5
Tan, L.6
Tan, I.7
Leung, T.8
Lim, L.9
-
69
-
-
84879101332
-
PAK family kinases: physiological roles and regulation
-
Manser E., Zhao Z.S. PAK family kinases: physiological roles and regulation. Cell Logist 2012, 2:59-68.
-
(2012)
Cell Logist
, vol.2
, pp. 59-68
-
-
Manser, E.1
Zhao, Z.S.2
-
70
-
-
20344391148
-
Outgrowth of neurites from NIE-115 neuroblastoma cells is prevented on repulsive substrates through the action of PAK
-
Marler K.J., Kozma R., Ahmed S., Dong J.M., Hall C., Lim L. Outgrowth of neurites from NIE-115 neuroblastoma cells is prevented on repulsive substrates through the action of PAK. Mol. Cell. Biol. 2005, 25:5226-5241.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 5226-5241
-
-
Marler, K.J.1
Kozma, R.2
Ahmed, S.3
Dong, J.M.4
Hall, C.5
Lim, L.6
-
71
-
-
0034721711
-
Actin-based plasticity in dendritic spines
-
Matus A. Actin-based plasticity in dendritic spines. Science 2000, 290:754-758.
-
(2000)
Science
, vol.290
, pp. 754-758
-
-
Matus, A.1
-
72
-
-
0043135185
-
DNA synthesis and neuronal apoptosis caused by familial Alzheimer disease mutants of the amyloid precursor protein are mediated by the p21 activated kinase PAK3
-
McPhie D.L., Coopersmith R., Hines-Peralta A., Chen Y., Ivins K.J., Manly S.P., Kozlowski M.R., Neve K.A., Neve R.L. DNA synthesis and neuronal apoptosis caused by familial Alzheimer disease mutants of the amyloid precursor protein are mediated by the p21 activated kinase PAK3. J. Neurosci. 2003, 23:6914-6927.
-
(2003)
J. Neurosci.
, vol.23
, pp. 6914-6927
-
-
McPhie, D.L.1
Coopersmith, R.2
Hines-Peralta, A.3
Chen, Y.4
Ivins, K.J.5
Manly, S.P.6
Kozlowski, M.R.7
Neve, K.A.8
Neve, R.L.9
-
73
-
-
22244449230
-
Abnormal long-lasting synaptic plasticity and cognition in mice lacking the mental retardation gene Pak3
-
Meng J., Meng Y., Hanna A., Janus C., Jia Z. Abnormal long-lasting synaptic plasticity and cognition in mice lacking the mental retardation gene Pak3. J. Neurosci. 2005, 25:6641-6650.
-
(2005)
J. Neurosci.
, vol.25
, pp. 6641-6650
-
-
Meng, J.1
Meng, Y.2
Hanna, A.3
Janus, C.4
Jia, Z.5
-
74
-
-
38049112896
-
A microarray study of gene and protein regulation in human and rat brain following middle cerebral artery occlusion
-
Mitsios N., Saka M., Krupinski J., Pennucci R., Sanfeliu C., Wang Q., Rubio F., Gaffney J., Kumar P., Kumar S., Sullivan M., Slevin M. A microarray study of gene and protein regulation in human and rat brain following middle cerebral artery occlusion. BMC Neurosci. 2007, 8:93.
-
(2007)
BMC Neurosci.
, vol.8
, pp. 93
-
-
Mitsios, N.1
Saka, M.2
Krupinski, J.3
Pennucci, R.4
Sanfeliu, C.5
Wang, Q.6
Rubio, F.7
Gaffney, J.8
Kumar, P.9
Kumar, S.10
Sullivan, M.11
Slevin, M.12
-
75
-
-
84879252044
-
PAK4-6 in cancer and neuronal development
-
Minden A. PAK4-6 in cancer and neuronal development. Cell. Logistics 2012, 2:95-104.
-
(2012)
Cell. Logistics
, vol.2
, pp. 95-104
-
-
Minden, A.1
-
76
-
-
84881519374
-
Identification of novel gene targets and functions of p21-activated kinase 1 during DNA damage by gene expression profiling
-
Motwani M., Li D.Q., Horvath A., Kumar R. Identification of novel gene targets and functions of p21-activated kinase 1 during DNA damage by gene expression profiling. PLoS ONE 2013, 8:e66585.
-
(2013)
PLoS ONE
, vol.8
, pp. e66585
-
-
Motwani, M.1
Li, D.Q.2
Horvath, A.3
Kumar, R.4
-
77
-
-
0028839660
-
The ADF/cofilin proteins: stimulus-responsive modulators of actin dynamics
-
Moon A., Drubin D.G. The ADF/cofilin proteins: stimulus-responsive modulators of actin dynamics. Mol. Biol. Cell 1995, 6:1423.
-
(1995)
Mol. Biol. Cell
, vol.6
, pp. 1423
-
-
Moon, A.1
Drubin, D.G.2
-
78
-
-
33845369874
-
Expression analysis of actin-related genes as an underlying mechanism for mood disorders
-
Nakatani N., Ohnishi T., Iwamoto K., Watanabe A., Iwayama Y., Yamashita S., Ishitsuka Y., Moriyama K., Nakajima M., Tatebayashi Y., Akiyama H., Higuchi T., Kato T., Yoshikawa T. Expression analysis of actin-related genes as an underlying mechanism for mood disorders. Biochem. Biophys. Res. Commun. 2007, 352:780-786.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.352
, pp. 780-786
-
-
Nakatani, N.1
Ohnishi, T.2
Iwamoto, K.3
Watanabe, A.4
Iwayama, Y.5
Yamashita, S.6
Ishitsuka, Y.7
Moriyama, K.8
Nakajima, M.9
Tatebayashi, Y.10
Akiyama, H.11
Higuchi, T.12
Kato, T.13
Yoshikawa, T.14
-
79
-
-
65149090058
-
Spine microdomains for postsynaptic signaling and plasticity
-
Newpher T.M., Ehlers M.D. Spine microdomains for postsynaptic signaling and plasticity. Trends Cell Biol. 2009, 19:218-227.
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 218-227
-
-
Newpher, T.M.1
Ehlers, M.D.2
-
80
-
-
0036245412
-
Differential distribution of α and β isoforms of p21-activated kinase in the monkey cerebral neocortex and hippocampus
-
Ong W.Y., Wang X.S., Manser E. Differential distribution of α and β isoforms of p21-activated kinase in the monkey cerebral neocortex and hippocampus. Exp. Brain Res. 2002, 144:189-199.
-
(2002)
Exp. Brain Res.
, vol.144
, pp. 189-199
-
-
Ong, W.Y.1
Wang, X.S.2
Manser, E.3
-
81
-
-
84890428609
-
BDNF mechanisms in late LTP formation: a synthesis and breakdown
-
Panja D., Bramham C.R. BDNF mechanisms in late LTP formation: a synthesis and breakdown. Neuropharmacology 2013, 76:664-676.
-
(2013)
Neuropharmacology
, vol.76
, pp. 664-676
-
-
Panja, D.1
Bramham, C.R.2
-
82
-
-
34249282040
-
MEK1 activation by PAK: a novel mechanism
-
Park E.R., Eblen S.T., Catling A.D. MEK1 activation by PAK: a novel mechanism. Cell. Signal. 2007, 19:1488-1496.
-
(2007)
Cell. Signal.
, vol.19
, pp. 1488-1496
-
-
Park, E.R.1
Eblen, S.T.2
Catling, A.D.3
-
83
-
-
0016251748
-
Dendritic spine "dysgenesis" and mental retardation
-
Purpura D.P. Dendritic spine "dysgenesis" and mental retardation. Science 1974, 186:1126-1128.
-
(1974)
Science
, vol.186
, pp. 1126-1128
-
-
Purpura, D.P.1
-
84
-
-
84872502206
-
Microdomains in forebrain spines: an ultrastructural perspective
-
Racz B., Weinberg R.J. Microdomains in forebrain spines: an ultrastructural perspective. Mol. Neurobiol. 2012, 47:77-89.
-
(2012)
Mol. Neurobiol.
, vol.47
, pp. 77-89
-
-
Racz, B.1
Weinberg, R.J.2
-
85
-
-
0031310102
-
Myosin phosphorylation by human cdc42-dependent S6/H4 kinase/gamma PAK from placenta and lymphoid cells
-
Ramos E., Wysolmerski R.B., Masaracchia R.A. Myosin phosphorylation by human cdc42-dependent S6/H4 kinase/gamma PAK from placenta and lymphoid cells. Recept Signal Trans. 1997, 7:99-110.
-
(1997)
Recept Signal Trans.
, vol.7
, pp. 99-110
-
-
Ramos, E.1
Wysolmerski, R.B.2
Masaracchia, R.A.3
-
86
-
-
0035966018
-
Phosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphology
-
Rashid T., Banerjee M., Nikolic M. Phosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphology. J. Biol. Chem. 2001, 276:49043-49052.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 49043-49052
-
-
Rashid, T.1
Banerjee, M.2
Nikolic, M.3
-
87
-
-
34547799307
-
Unconventional myosins in muscle
-
Redowicz M.J. Unconventional myosins in muscle. Eur. J. Cell Biol. 2007, 86:549-558.
-
(2007)
Eur. J. Cell Biol.
, vol.86
, pp. 549-558
-
-
Redowicz, M.J.1
-
88
-
-
67650490390
-
Different Rho GTPase-dependent signaling pathways initiate sequential steps in the consolidation of long-term potentiation
-
Rex C.S., Chen L.Y., Sharma A., Liu J., Babayan A.H., Gall C.M., Lynch G. Different Rho GTPase-dependent signaling pathways initiate sequential steps in the consolidation of long-term potentiation. J. Cell Biol. 2009, 186:85-97.
-
(2009)
J. Cell Biol.
, vol.186
, pp. 85-97
-
-
Rex, C.S.1
Chen, L.Y.2
Sharma, A.3
Liu, J.4
Babayan, A.H.5
Gall, C.M.6
Lynch, G.7
-
89
-
-
0037423285
-
A new constitutively active brain PAK3 isoform displays modified specificities toward Rac and Cdc42 GTPases
-
Rousseau V., Goupille O., Morin N., Barnier J.V. A new constitutively active brain PAK3 isoform displays modified specificities toward Rac and Cdc42 GTPases. J. Biol. Chem. 2003, 278:3912-3920.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 3912-3920
-
-
Rousseau, V.1
Goupille, O.2
Morin, N.3
Barnier, J.V.4
-
90
-
-
84860211462
-
Abnormalities of the Duo/Ras-related C3 botulinum toxin substrate 1/p21-activated kinase 1 pathway drive myosin light chain phosphorylation in frontal cortex in schizophrenia
-
Rubio M.D., Haroutunian V., Meador-Woodruff J.H. Abnormalities of the Duo/Ras-related C3 botulinum toxin substrate 1/p21-activated kinase 1 pathway drive myosin light chain phosphorylation in frontal cortex in schizophrenia. Biol. Psychiatry 2012, 71:906-914.
-
(2012)
Biol. Psychiatry
, vol.71
, pp. 906-914
-
-
Rubio, M.D.1
Haroutunian, V.2
Meador-Woodruff, J.H.3
-
91
-
-
0031105660
-
Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells
-
Sells M.A., Knaus U.G., Bagrodia S., Ambrose D.M., Bokoch G.M., Chernoff J. Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells. Curr. Biol. 1997, 7:202-210.
-
(1997)
Curr. Biol.
, vol.7
, pp. 202-210
-
-
Sells, M.A.1
Knaus, U.G.2
Bagrodia, S.3
Ambrose, D.M.4
Bokoch, G.M.5
Chernoff, J.6
-
92
-
-
0033577902
-
P21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts
-
Sells M.A., Boyd J.T., Chernoff J. P21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts. J. Cell Biol. 1999, 145:837-849.
-
(1999)
J. Cell Biol.
, vol.145
, pp. 837-849
-
-
Sells, M.A.1
Boyd, J.T.2
Chernoff, J.3
-
93
-
-
0034677906
-
Myosins: a diverse superfamily. Biochimica et Biophysica Acta (BBA)-Molecular
-
Sellers J.R. Myosins: a diverse superfamily. Biochimica et Biophysica Acta (BBA)-Molecular. Cell Res. 2000, 1496:3-22.
-
(2000)
Cell Res.
, vol.1496
, pp. 3-22
-
-
Sellers, J.R.1
-
94
-
-
0347155585
-
Phosphorylation of p85 -PIX, a Rac/Cdc42-specific guanine nucleotide exchange factor, via the Ras/ERK/PAK2 pathway is required for basic fibroblast growth factor-induced neurite outgrowth
-
Shin E.Y., Shin K.S., Lee C.S., Woo K.N., Quan S.H., Soung N.K., Kim Y.G., Cha C.I., Kim S.R., Park D., Bokoch G.M., Kim E.G. Phosphorylation of p85 -PIX, a Rac/Cdc42-specific guanine nucleotide exchange factor, via the Ras/ERK/PAK2 pathway is required for basic fibroblast growth factor-induced neurite outgrowth. J. Biol. Chem. 2002, 277:44417-44430.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44417-44430
-
-
Shin, E.Y.1
Shin, K.S.2
Lee, C.S.3
Woo, K.N.4
Quan, S.H.5
Soung, N.K.6
Kim, Y.G.7
Cha, C.I.8
Kim, S.R.9
Park, D.10
Bokoch, G.M.11
Kim, E.G.12
-
95
-
-
84884478326
-
Protein kinase CK2 phosphorylates and activates p21-activated kinase 1
-
Shin Y., Kim Y., Kim J. Protein kinase CK2 phosphorylates and activates p21-activated kinase 1. Mol. Biol. Cell 2013, 24:2990-2999.
-
(2013)
Mol. Biol. Cell
, vol.24
, pp. 2990-2999
-
-
Shin, Y.1
Kim, Y.2
Kim, J.3
-
96
-
-
52149106669
-
Cellular signaling for activation of Rho GTPase Cdc42
-
Sinha S., Yang W. Cellular signaling for activation of Rho GTPase Cdc42. Cell. Signal. 2008, 20:1927-1934.
-
(2008)
Cell. Signal.
, vol.20
, pp. 1927-1934
-
-
Sinha, S.1
Yang, W.2
-
97
-
-
79952779502
-
Rho GTPases and their role in organizing the actin cytoskeleton
-
Sit S.T., Manser E. Rho GTPases and their role in organizing the actin cytoskeleton. J. Cell Sci. 2011, 124:679-683.
-
(2011)
J. Cell Sci.
, vol.124
, pp. 679-683
-
-
Sit, S.T.1
Manser, E.2
-
98
-
-
59549099037
-
PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics
-
Smith S.D., Jaffer Z.M., Chernoff J., Ridley A.J. PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics. J. Cell Sci. 2008, 121:3729-3736.
-
(2008)
J. Cell Sci.
, vol.121
, pp. 3729-3736
-
-
Smith, S.D.1
Jaffer, Z.M.2
Chernoff, J.3
Ridley, A.J.4
-
100
-
-
55049095633
-
Understanding synapses: past, present, and future
-
Sudhof T.C., Malenka R.C. Understanding synapses: past, present, and future. Neuron 2008, 60:469-476.
-
(2008)
Neuron
, vol.60
, pp. 469-476
-
-
Sudhof, T.C.1
Malenka, R.C.2
-
101
-
-
0141751697
-
Calcium sensitivity of smooth muscle and non-muscle myosin II: modulation by G proteins, kinases, and myosin phosphatase
-
Somlyo A.P., Somlyo A.V. Calcium sensitivity of smooth muscle and non-muscle myosin II: modulation by G proteins, kinases, and myosin phosphatase. Physiol. Rev. 2003, 83:1325-1358.
-
(2003)
Physiol. Rev.
, vol.83
, pp. 1325-1358
-
-
Somlyo, A.P.1
Somlyo, A.V.2
-
102
-
-
0037011113
-
XPak3 promotes cell cycle withdrawal during primary neurogenesis in Xenopus laevis
-
Souopgui J., Sölter M., Pieler T. XPak3 promotes cell cycle withdrawal during primary neurogenesis in Xenopus laevis. EMBO J. 2002, 21:6429-6439.
-
(2002)
EMBO J.
, vol.21
, pp. 6429-6439
-
-
Souopgui, J.1
Sölter, M.2
Pieler, T.3
-
103
-
-
68249113742
-
Involvement of Rac/Cdc42/PAK pathway in cytoskeletal rearrangements
-
Szczepanowska J. Involvement of Rac/Cdc42/PAK pathway in cytoskeletal rearrangements. Acta Biochim. Pol. 2009, 56:225-234.
-
(2009)
Acta Biochim. Pol.
, vol.56
, pp. 225-234
-
-
Szczepanowska, J.1
-
104
-
-
0030811528
-
Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts
-
Tang Y., Chen Z., Ambrose D., Liu J., Gibbs J.B., Chernoff J., Field J. Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts. Mol. Cell. Biol. 1997, 17:4454-4464.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 4454-4464
-
-
Tang, Y.1
Chen, Z.2
Ambrose, D.3
Liu, J.4
Gibbs, J.B.5
Chernoff, J.6
Field, J.7
-
105
-
-
0028842508
-
Identification and molecular cloning of a p21cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets
-
Teo M., Manser E., Lim L. Identification and molecular cloning of a p21cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets. J. Biol. Chem. 1995, 270:26690-26697.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 26690-26697
-
-
Teo, M.1
Manser, E.2
Lim, L.3
-
106
-
-
81155154278
-
P21-Activated kinase 3 (PAK3) protein regulates synaptic transmission through its interaction with the Nck2/Grb4 protein adaptor
-
Thévenot E., Moreau A.W., Rousseau V., Combeau G., Domenichini F., Jacquet C., Goupille O., Amar M., Kreis P., Fossier P., Barnier J.V. P21-Activated kinase 3 (PAK3) protein regulates synaptic transmission through its interaction with the Nck2/Grb4 protein adaptor. J. Biol. Chem. 2011, 286:40044-40059.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 40044-40059
-
-
Thévenot, E.1
Moreau, A.W.2
Rousseau, V.3
Combeau, G.4
Domenichini, F.5
Jacquet, C.6
Goupille, O.7
Amar, M.8
Kreis, P.9
Fossier, P.10
Barnier, J.V.11
-
107
-
-
0037162289
-
Cell cycle regulated phosphorylation of p21-activated kinase 1
-
Thiel D.A., Reeder M.K., Pfaff A., Coleman T.R., Sells M.A., Chernoff J.A. Cell cycle regulated phosphorylation of p21-activated kinase 1. Curr. Biol. 2002, 12:1227-1232.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1227-1232
-
-
Thiel, D.A.1
Reeder, M.K.2
Pfaff, A.3
Coleman, T.R.4
Sells, M.A.5
Chernoff, J.A.6
-
108
-
-
82955205873
-
Structural insights into the autoactivation mechanism of p21-activated protein kinase
-
Wang J., Wu J.W., Wang Z.X. Structural insights into the autoactivation mechanism of p21-activated protein kinase. Structure 2011, 19:1752-1761.
-
(2011)
Structure
, vol.19
, pp. 1752-1761
-
-
Wang, J.1
Wu, J.W.2
Wang, Z.X.3
-
109
-
-
84880076560
-
P21-activated Kinase1(PAK1) can promote ERK activation in a kinase independent manner
-
Wang Z., Fu M., Wang L., Liu J., Li Y., Brakebusch C., Mei Q. P21-activated Kinase1(PAK1) can promote ERK activation in a kinase independent manner. J. Biol. Chem. 2013, 288:20093-20099.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 20093-20099
-
-
Wang, Z.1
Fu, M.2
Wang, L.3
Liu, J.4
Li, Y.5
Brakebusch, C.6
Mei, Q.7
-
110
-
-
0038511012
-
Inhibition of contraction and myosin light chain phosphorylation in guinea-pig smooth muscle by p21-activated kinase 1
-
Wirth A., Schroeter M., Kock-Hauser C., Manser E., Chalovich J.M., De Lanerolle P., Pfitzer G. Inhibition of contraction and myosin light chain phosphorylation in guinea-pig smooth muscle by p21-activated kinase 1. J. Physiol. 2003, 549:489-500.
-
(2003)
J. Physiol.
, vol.549
, pp. 489-500
-
-
Wirth, A.1
Schroeter, M.2
Kock-Hauser, C.3
Manser, E.4
Chalovich, J.M.5
De Lanerolle, P.6
Pfitzer, G.7
-
111
-
-
0036711657
-
Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1
-
Vadlamudi R.K., Li F., Adam L., Nguyen D., Ohta Y., Stossel T.P., Kumar R. Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1. Nat. Cell Biol. 2002, 4:681-690.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 681-690
-
-
Vadlamudi, R.K.1
Li, F.2
Adam, L.3
Nguyen, D.4
Ohta, Y.5
Stossel, T.P.6
Kumar, R.7
-
112
-
-
15144358616
-
Different molecular mechanisms for Rho family GTPase-dependent, Ca2 independent contraction of smooth muscle
-
Van Eyk J.E., Arrell D.K., Foster D.B., Strauss J.D., Heinonen T.Y., Furmaniak- Kazmierczak E., Cote G.P., Mak A.S. Different molecular mechanisms for Rho family GTPase-dependent, Ca2 independent contraction of smooth muscle. J. Biol. Chem. 1998, 273:23433-23439.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 23433-23439
-
-
Van Eyk, J.E.1
Arrell, D.K.2
Foster, D.B.3
Strauss, J.D.4
Heinonen, T.Y.5
Furmaniak-Kazmierczak, E.6
Cote, G.P.7
Mak, A.S.8
-
113
-
-
70350348363
-
Structure and function of dendritic spines within the hippocampus
-
von Bohlen, Halbach O. Structure and function of dendritic spines within the hippocampus. Ann Anat. 2009, 191:518-531.
-
(2009)
Ann Anat.
, vol.191
, pp. 518-531
-
-
von Bohlen, G.K.1
Halbach, O.2
-
114
-
-
84876011758
-
PAK signaling in cancer
-
Ye D.Z., Field J. PAK signaling in cancer. Cell Logist 2012, 2:105-116.
-
(2012)
Cell Logist
, vol.2
, pp. 105-116
-
-
Ye, D.Z.1
Field, J.2
-
115
-
-
77954216859
-
Development of smallmolecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer
-
Yi C., Maksimoska J., Marmorstein R., Kissil J.L. Development of smallmolecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer. Biochem. Pharmacol. 2010, 80:683-689.
-
(2010)
Biochem. Pharmacol.
, vol.80
, pp. 683-689
-
-
Yi, C.1
Maksimoska, J.2
Marmorstein, R.3
Kissil, J.L.4
-
116
-
-
0034928790
-
Morphological changes in dendritic spines associated with long-term synaptic plasticity
-
Yuste R., Bonhoeffer T. Morphological changes in dendritic spines associated with long-term synaptic plasticity. Annu. Rev. Neurosci. 2001, 24:1071-1089.
-
(2001)
Annu. Rev. Neurosci.
, vol.24
, pp. 1071-1089
-
-
Yuste, R.1
Bonhoeffer, T.2
-
117
-
-
0346024190
-
Genesis of dendritic spines: insights from ultrastructural and imaging studies
-
Yuste R., Bonhoeffer T. Genesis of dendritic spines: insights from ultrastructural and imaging studies. Nat. Rev. Neurosci. 2004, 5:24-34.
-
(2004)
Nat. Rev. Neurosci.
, vol.5
, pp. 24-34
-
-
Yuste, R.1
Bonhoeffer, T.2
-
118
-
-
0037040291
-
Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1
-
Zang M., Hayne C., Luo Z. Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1. J. Biol. Chem. 2002, 277:4395-4405.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4395-4405
-
-
Zang, M.1
Hayne, C.2
Luo, Z.3
-
119
-
-
57649129418
-
Characterization of S338 phosphorylation for Raf-1 activation
-
Zang M., Gong J., Luo L., Zhou J., Xiang X., Huang W., Huang Q., Luo X., Olbrot M., Peng Y., Chen C., Luo Z. Characterization of S338 phosphorylation for Raf-1 activation. J. Biol. Chem. 2008, 283:31429-31437.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 31429-31437
-
-
Zang, M.1
Gong, J.2
Luo, L.3
Zhou, J.4
Xiang, X.5
Huang, W.6
Huang, Q.7
Luo, X.8
Olbrot, M.9
Peng, Y.10
Chen, C.11
Luo, Z.12
-
120
-
-
0032748298
-
Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity
-
Zenke F.T., King C.C., Bohl B.P., Bokoch G.M. Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity. J. Biol. Chem. 1999, 274:32565-32573.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32565-32573
-
-
Zenke, F.T.1
King, C.C.2
Bohl, B.P.3
Bokoch, G.M.4
-
121
-
-
16344390935
-
A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC
-
Zhang H., Webb D.J., Asmussen H., Niu S., Horwitz A.F. A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC. J. Neurosci. 2005, 25:3379-3388.
-
(2005)
J. Neurosci.
, vol.25
, pp. 3379-3388
-
-
Zhang, H.1
Webb, D.J.2
Asmussen, H.3
Niu, S.4
Horwitz, A.F.5
-
122
-
-
84890173885
-
A 3D Alzheimer's disease culture model and the induction of p21-activated kinase mediated sensing in iPSC derived neurons
-
Zhang D., Pekkanen-Mattila M., Shahsavani M., Falk A., Teixeira A.I., Herland A. A 3D Alzheimer's disease culture model and the induction of p21-activated kinase mediated sensing in iPSC derived neurons. Biomaterials 2013, 35:1420-1428.
-
(2013)
Biomaterials
, vol.35
, pp. 1420-1428
-
-
Zhang, D.1
Pekkanen-Mattila, M.2
Shahsavani, M.3
Falk, A.4
Teixeira, A.I.5
Herland, A.6
-
123
-
-
0242664130
-
Akt phosphorylation of serine 21 on Pak1 modulates Nck binding and cell migration
-
Zhou G., Zhuo Y., King C.C., Fryer B.H., Bokoch G.M., Field J. Akt phosphorylation of serine 21 on Pak1 modulates Nck binding and cell migration. Mol. Cell. Biol. 2003, 23:8058-8069.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8058-8069
-
-
Zhou, G.1
Zhuo, Y.2
King, C.C.3
Fryer, B.H.4
Bokoch, G.M.5
Field, J.6
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