MEK1 activation by PAK: A novel mechanism

Cellular Signalling

Volumn 19, Issue 7, 2007, Pages 1488-1496

  Park, Electa R ^a   Eblen, Scott T ^b   Catling, Andrew D ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Adhesion; ERK; MEK; PAK; Phosphorylation; Raf 1; Signaling

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; P21 ACTIVATED KINASE; RAF PROTEIN; RAS PROTEIN; SERINE;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CELL ADHESION; CELL LINE; CELL MIGRATION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; TISSUE CULTURE;

ANIMALS; CELL ADHESION; CERCOPITHECUS AETHIOPS; COS CELLS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; FIBRONECTINS; HUMANS; MAP KINASE KINASE 1; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS B-RAF; RAS PROTEINS; RATS; SERINE;

EID: 34249282040     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2007.01.018     Document Type: Article

References (68)

1. Lin T.H., Chen Q., Howe A., and Juliano R.L. J. Biol. Chem. 272 (1997) 8849
2. Renshaw M.W., Ren X.D., and Schwartz M.A. EMBO J. 16 (1997) 5592
3. Bagrodia S., and Cerione R.A. Trends Cell Biol. 9 (1999) 350
4. Khosravi-Far R., Solski P.A., Clark G.J., Kinch M.S., and Der C.J. Mol. Cell. Biol. 15 (1995) 6443
5. Qiu R.G., Chen J., Kirn D., McCormick F., and Symons M. Nature 374 (1995) 457
6. Tang Y., Chen Z., Ambrose D., Liu J., Gibbs J.B., Chernoff J., and Field J. Mol. Cell. Biol. 17 (1997) 4454
7. Vadlamudi R.K., Adam L., Wang R.A., Mandal M., Nguyen D., Sahin A., Chernoff J., Hung M.C., and Kumar R. J. Biol. Chem. 275 (2000) 36238
8. Qu J., Cammarano M.S., Shi Q., Ha K.C., de Lanerolle P., and Minden A. Mol. Cell. Biol. 21 (2001) 3523
9. Stofega M.R., Sanders L.C., Gardiner E.M., and Bokoch G.M. Mol. Biol. Cell 15 (2004) 2965
10. Mira J.P., Benard V., Groffen J., Sanders L.C., and Knaus U.G. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 185
11. Minden A., Lin A., Claret F.X., Abo A., and Karin M. Cell 81 (1995) 1147
12. Frost J.A., Xu S., Hutchison M.R., Marcus S., and Cobb M.H. Mol. Cell. Biol. 16 (1996) 3707
13. Coso O.A., Chiariello M., Yu J.C., Teramoto H., Crespo P., Xu N., Miki T., and Gutkind J.S. Cell 81 (1995) 1137
14. Frost J.A., Steen H., Shapiro P., Lewis T., Ahn N., Shaw P.E., and Cobb M.H. EMBO J. 16 (1997) 6426
15. Coles L.C., and Shaw P.E. Oncogene 21 (2002) 2236
16. Beeser A., and Chernoff J. Methods 37 (2005) 203
17. Howe A.K., and Juliano R.L. Nat. Cell Biol. 2 (2000) 593
18. Eblen S.T., Slack J.K., Weber M.J., and Catling A.D. Mol. Cell. Biol. 22 (2002) 6023
19. King A.J., Sun H., Diaz B., Barnard D., Miao W., Bagrodia S., and Marshall M.S. Nature 396 (1998) 180
20. Sun H., King A.J., Diaz H.B., and Marshall M.S. Curr. Biol. 10 (2000) 281
21. Chaudhary A., King W.G., Mattaliano M.D., Frost J.A., Diaz B., Morrison D.K., Cobb M.H., Marshall M.S., and Brugge J.S. Curr. Biol. 10 (2000) 551
22. Edin M.L., and Juliano R.L. Mol. Cell. Biol. 25 (2005) 4466
23. Chiloeches A., Mason C.S., and Marais R. Mol. Cell. Biol. 21 (2001) 2423
24. Slack-Davis J.K., Eblen S.T., Zecevic M., Boerner S.A., Tarcsafalvi A., Diaz H.B., Marshall M.S., Weber M.J., Parsons J.T., and Catling A.D. J. Cell Biol. 162 (2003) 281
25. Xiang X., Zang M., Waelde C.A., Wen R., and Luo Z. J. Biol. Chem. 277 (2002) 44996
26. Eblen S.T., Slack-Davis J.K., Tarcsafalvi A., Parsons J.T., Weber M.J., and Catling A.D. Mol. Cell. Biol. 24 (2004) 2308
27. Catling A.D., Schaeffer H.J., Reuter C.W., Reddy G.R., and Weber M.J. Mol. Cell. Biol. 15 (1995) 5214
28. Chen Q., Lin T.H., Der C.J., and Juliano R.L. J. Biol. Chem. 271 (1996) 18122
29. Clark E.A., and Hynes R.O. J. Biol. Chem. 271 (1996) 14814
30. King W.G., Mattaliano M.D., Chan T.O., Tsichlis P.N., and Brugge J.S. Mol. Cell. Biol. 17 (1997) 4406
31. Pritchard C.A., Hayes L., Wojnowski L., Zimmer A., Marais R.M., and Norman J.C. Mol. Cell. Biol. 24 (2004) 5937
32. Wojnowski L., Stancato L.F., Larner A.C., Rapp U.R., and Zimmer A. Mech. Dev. 91 (2000) 97
33. Huser M., Luckett J., Chiloeches A., Mercer K., Iwobi M., Giblett S., Sun X.M., Brown J., Marais R., and Pritchard C. EMBO J. 20 (2001) 1940
34. Mikula M., Schreiber M., Husak Z., Kucerova L., Ruth J., Wieser R., Zatloukal K., Beug H., Wagner E.F., and Baccarini M. EMBO J. 20 (2001) 1952
35. Mercer K., Chiloeches A., Huser M., Kiernan M., Marais R., and Pritchard C. Oncogene 21 (2002) 347
36. Weed S.A., Du Y., and Parsons J.T. J. Cell Sci. 111 Pt 16 (1998) 2433
37. Catling A.D., Eblen S.T., Schaeffer H.J., and Weber M.J. Methods Enzymol. 332 (2001) 368
38. Robbins D.J., Zhen E., Owaki H., Vanderbilt C.A., Ebert D., Geppert T.D., and Cobb M.H. J. Biol. Chem. 268 (1993) 5097
39. Schaeffer H.J., Catling A.D., Eblen S.T., Collier L.S., Krauss A., and Weber M.J. Science 281 (1998) 1668
40. Zheng C.F., and Guan K.L. EMBO J. 13 (1994) 1123
41. Alessi D.R., Saito Y., Campbell D.G., Cohen P., Sithanandam G., Rapp U., Ashworth A., Marshall C.J., and Cowley S. EMBO J. 13 (1994) 1610
42. Favata M.F., Horiuchi K.Y., Manos E.J., Daulerio A.J., Stradley D.A., Feeser W.S., Van Dyk D.E., Pitts W.J., Earl R.A., Hobbs F., Copeland R.A., Magolda R.L., Scherle P.A., and Trzaskos J.M. J. Biol. Chem. 273 (1998) 18623
43. Resing K.A., Mansour S.J., Hermann A.S., Johnson R.S., Candia J.M., Fukasawa K., Vande Woude G.F., and Ahn N.G. Biochemistry 34 (1995) 2610
44. Brunet A., Pages G., and Pouyssegur J. FEBS Lett. 346 (1994) 299
45. Schaeffer H.J., and Weber M.J. Mol. Cell. Biol. 19 (1999) 2435
46. Pullikuth A., McKinnon E., Schaeffer H.J., and Catling A.D. Mol. Cell. Biol. 25 (2005) 5119
47. Vomastek T., Schaeffer H.J., Tarcsafalvi A., Smolkin M.E., Bissonette E.A., and Weber M.J. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 6981
48. Kolch W. Nat. Rev., Mol. Cell Biol. 6 (2005) 827
49. Yin G., Zheng Q., Yan C., and Berk B.C. J. Biol. Chem. 280 (2005) 27705
50. Yin G., Haendeler J., Yan C., and Berk B.C. Mol. Cell. Biol. 24 (2004) 875
51. Turner C.E., Brown M.C., Perrotta J.A., Riedy M.C., Nikolopoulos S.N., McDonald A.R., Bagrodia S., Thomas S., and Leventhal P.S. J. Cell Biol. 145 (1999) 851
52. Zheng C.F., and Guan K.L. J. Biol. Chem. 268 (1993) 23933
53. Rossomando A.J., Dent P., Sturgill T.W., and Marshak D.R. Mol. Cell. Biol. 14 (1994) 1594
54. Ohren J.F., Chen H., Pavlovsky A., Whitehead C., Zhang E., Kuffa P., Yan C., McConnell P., Spessard C., Banotai C., Mueller W.T., Delaney A., Omer C., Sebolt-Leopold J., Dudley D.T., Leung I.K., Flamme C., Warmus J., Kaufman M., Barrett S., Tecle H., and Hasemann C.A. Nat. Struct. Mol. Biol. 11 (2004) 1192
55. Sebolt-Leopold J.S., Dudley D.T., Herrera R., Van Becelaere K., Wiland A., Gowan R.C., Tecle H., Barrett S.D., Bridges A., Przybranowski S., Leopold W.R., and Saltiel A.R. Nat. Med. 5 (1999) 810
56. Manser E., Leung T., and Lim L. Methods Mol. Biol. 84 (1998) 295
57. del Pozo M.A., Price L.S., Alderson N.B., Ren X.D., and Schwartz M.A. EMBO J. 19 (2000) 2008
58. West K.A., Zhang H., Brown M.C., Nikolopoulos S.N., Riedy M.C., Horwitz A.F., and Turner C.E. J. Cell Biol. 154 (2001) 161
59. Zhao Z.S., Manser E., Chen X.Q., Chong C., Leung T., and Lim L. Mol. Cell. Biol. 18 (1998) 2153
60. Fincham V.J., James M., Frame M.C., and Winder S.J. EMBO J. 19 (2000) 2911
61. Webb D.J., Donais K., Whitmore L.A., Thomas S.M., Turner C.E., Parsons J.T., and Horwitz A.F. Nat. Cell Biol. 6 (2004) 154
62. Belanger L.F., Roy S., Tremblay M., Brott B., Steff A.M., Mourad W., Hugo P., Erikson R., and Charron J. Mol. Cell. Biol. 23 (2003) 4778
63. Giroux S., Tremblay M., Bernard D., Cardin-Girard J.F., Aubry S., Larouche L., Rousseau S., Huot J., Landry J., Jeannotte L., and Charron J. Curr. Biol. 9 (1999) 369
64. Vadlamudi R.K., and Kumar R. Cancer Metastasis Rev. 22 (2003) 385
65. Slack J.K., Adams R.B., Rovin J.D., Bissonette E.A., Stoker C.E., and Parsons J.T. Oncogene 20 (2001) 1152
66. Owens L.V., Xu L., Craven R.J., Dent G.A., Weiner T.M., Kornberg L., Liu E.T., and Cance W.G. Cancer Res. 55 (1995) 2752
67. Dhillon A.S., Meikle S., Yazici Z., Eulitz M., and Kolch W. EMBO J. 21 (2002) 64
68. Harding A., Hsu V., Kornfeld K., and Hancock J.F. J. Biol. Chem. 278 (2003) 45519