Abnormalities of the Duo/Ras-related C3 botulinum toxin substrate 1/p21-activated kinase 1 pathway drive myosin light chain phosphorylation in frontal cortex in schizophrenia

Biological Psychiatry

Volumn 71, Issue 10, 2012, Pages 906-914

  Rubio, Mara D ^a   Haroutunian, Vahram ^b   Meador Woodruff, James H ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Cofilin; cytoskeleton; dendritic spines; GTPases; kalirin; LIM domain kinase (LIMK)

Indexed keywords

COFILIN; HALOPERIDOL DECANOATE; MYOSIN LIGHT CHAIN; P21 ACTIVATED KINASE 1; PROTEIN CDC42; RAC1 PROTEIN;

ACTIN FILAMENT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTERIOR CINGULATE; ARTICLE; AUTOPSY; CONTROLLED STUDY; DENDRITIC SPINE; FEMALE; FRONTAL CORTEX; HUMAN; MALE; MOUSE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AGED; AGED, 80 AND OVER; ANIMALS; CASE-CONTROL STUDIES; CDC42 GTP-BINDING PROTEIN; CYTOSKELETON; DENDRITIC SPINES; FEMALE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; GYRUS CINGULI; HUMANS; MALE; MYOSIN LIGHT CHAINS; P21-ACTIVATED KINASES; PHOSPHORYLATION; PREFRONTAL CORTEX; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; SCHIZOPHRENIA;

EID: 84860211462     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2012.02.006     Document Type: Article

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