-
1
-
-
84862737662
-
Identification of pancreatic cancer stem cells and selective toxicity of chemotherapeutic agents
-
Adikrisna R., Tanaka S., Muramatsu S., Aihara A., Ban D., Ochiai T., et al. Identification of pancreatic cancer stem cells and selective toxicity of chemotherapeutic agents. Gastroenterol 2012, 143(234-245):e237.
-
(2012)
Gastroenterol
, vol.143
, Issue.234-245
, pp. e237
-
-
Adikrisna, R.1
Tanaka, S.2
Muramatsu, S.3
Aihara, A.4
Ban, D.5
Ochiai, T.6
-
2
-
-
49249091523
-
Identification and characterization of ovarian cancer-initiating cells from primary human tumors
-
Zhang S., Balch C., Chan M.W., Lai H.-C., Matei D., Schilder J.M., et al. Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Res 2008, 68:4311-4320.
-
(2008)
Cancer Res
, vol.68
, pp. 4311-4320
-
-
Zhang, S.1
Balch, C.2
Chan, M.W.3
Lai, H.-C.4
Matei, D.5
Schilder, J.M.6
-
3
-
-
38349165576
-
Identification of cells initiating human melanomas
-
Schatton T., Murphy G.F., Frank N.Y., Yamaura K., Waaga-Gasser A.M., Gasser M., et al. Identification of cells initiating human melanomas. Nature 2008, 451:345-349.
-
(2008)
Nature
, vol.451
, pp. 345-349
-
-
Schatton, T.1
Murphy, G.F.2
Frank, N.Y.3
Yamaura, K.4
Waaga-Gasser, A.M.5
Gasser, M.6
-
4
-
-
60949084535
-
Cancer stem cells: a model in the making
-
Marotta L.L.C., Polyak K. Cancer stem cells: a model in the making. Curr Opin Genet Dev 2009, 19:44-50.
-
(2009)
Curr Opin Genet Dev
, vol.19
, pp. 44-50
-
-
Marotta, L.L.C.1
Polyak, K.2
-
5
-
-
84872405099
-
Reprogramming cancer stem cells
-
Tafani M., Russo M. Reprogramming cancer stem cells. J Cancer Sci Ther 2012, 4:25-26.
-
(2012)
J Cancer Sci Ther
, vol.4
, pp. 25-26
-
-
Tafani, M.1
Russo, M.2
-
6
-
-
84883828891
-
Knockdown of Oct4 and Nanog expression inhibits the stemness of pancreatic cancer cells
-
Lu Y., Zhu H., Shan H., Lu J., Chang X., Li X., et al. Knockdown of Oct4 and Nanog expression inhibits the stemness of pancreatic cancer cells. Cancer Lett 2013, 340:113-123.
-
(2013)
Cancer Lett
, vol.340
, pp. 113-123
-
-
Lu, Y.1
Zhu, H.2
Shan, H.3
Lu, J.4
Chang, X.5
Li, X.6
-
7
-
-
67649612847
-
Alternative translation of OCT4 by an internal ribosome entry site and its novel function in stress response
-
Wang X., Zhao Y., Xiao Z., Chen B., Wei Z., Wang B., et al. Alternative translation of OCT4 by an internal ribosome entry site and its novel function in stress response. Stem Cells 2009, 27:1265-1275.
-
(2009)
Stem Cells
, vol.27
, pp. 1265-1275
-
-
Wang, X.1
Zhao, Y.2
Xiao, Z.3
Chen, B.4
Wei, Z.5
Wang, B.6
-
8
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
Ben-Porath I., Thomson M.W., Carey V.J., Ge R., Bell G.W., Regev A., et al. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 2008, 40:499-507.
-
(2008)
Nat Genet
, vol.40
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
Ge, R.4
Bell, G.W.5
Regev, A.6
-
9
-
-
34548233165
-
Calcium signalling in lymphocyte activation and disease
-
Feske S. Calcium signalling in lymphocyte activation and disease. Nat Rev Immunol 2007, 7:690-702.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 690-702
-
-
Feske, S.1
-
10
-
-
85027923138
-
NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation
-
Jeter C.R., Liu B., Liu X., Chen X., Liu C., Calhoun-Davis T., et al. NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation. Oncogene 2011, 30:3833-3845.
-
(2011)
Oncogene
, vol.30
, pp. 3833-3845
-
-
Jeter, C.R.1
Liu, B.2
Liu, X.3
Chen, X.4
Liu, C.5
Calhoun-Davis, T.6
-
11
-
-
84866103351
-
Dysregulated stemness-related genes in gynecological malignancies
-
Mak V., Siu M., Wong O., Chan K., Ngan H., Cheung A. Dysregulated stemness-related genes in gynecological malignancies. Histol Histopathol 2012, 27:1121-1130.
-
(2012)
Histol Histopathol
, vol.27
, pp. 1121-1130
-
-
Mak, V.1
Siu, M.2
Wong, O.3
Chan, K.4
Ngan, H.5
Cheung, A.6
-
12
-
-
78650389774
-
Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation
-
Chiou S.-H., Wang M.-L., Chou Y.-T., Chen C.-J., Hong C.-F., Hsieh W.-J., et al. Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation. Cancer Res 2010, 70:10433-10444.
-
(2010)
Cancer Res
, vol.70
, pp. 10433-10444
-
-
Chiou, S.-H.1
Wang, M.-L.2
Chou, Y.-T.3
Chen, C.-J.4
Hong, C.-F.5
Hsieh, W.-J.6
-
13
-
-
41449118521
-
Module map of stem cell genes guides creation of epithelial cancer stem cells
-
Wong D.J., Liu H., Ridky T.W., Cassarino D., Segal E., Chang H.Y. Module map of stem cell genes guides creation of epithelial cancer stem cells. Cell Stem Cell 2008, 2:333-344.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 333-344
-
-
Wong, D.J.1
Liu, H.2
Ridky, T.W.3
Cassarino, D.4
Segal, E.5
Chang, H.Y.6
-
14
-
-
36849088519
-
The theoretical basis of cancer-stem-cell-based therapeutics of cancer: can it be put into practice?
-
Sánchez-García I., Vicente-Dueñas C., Cobaleda C. The theoretical basis of cancer-stem-cell-based therapeutics of cancer: can it be put into practice?. BioEssays 2007, 29:1269-1280.
-
(2007)
BioEssays
, vol.29
, pp. 1269-1280
-
-
Sánchez-García, I.1
Vicente-Dueñas, C.2
Cobaleda, C.3
-
15
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T., Morrison S.J., Clarke M.F., Weissman I.L. Stem cells, cancer, and cancer stem cells. Nature 2001, 414:105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
16
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
17
-
-
84862528505
-
Induced pluripotent stem cells: past, present, and future
-
Yamanaka S. Induced pluripotent stem cells: past, present, and future. Cell Stem Cell 2012, 10:678-684.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 678-684
-
-
Yamanaka, S.1
-
18
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
-
19
-
-
34249909232
-
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
-
Maherali N., Sridharan R., Xie W., Utikal J., Eminli S., Arnold K., et al. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 2007, 1:55-70.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 55-70
-
-
Maherali, N.1
Sridharan, R.2
Xie, W.3
Utikal, J.4
Eminli, S.5
Arnold, K.6
-
20
-
-
64749083939
-
PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
-
Woltjen K., Michael I.P., Mohseni P., Desai R., Mileikovsky M., Hämäläinen R., et al. PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 2009, 458:766-770.
-
(2009)
Nature
, vol.458
, pp. 766-770
-
-
Woltjen, K.1
Michael, I.P.2
Mohseni, P.3
Desai, R.4
Mileikovsky, M.5
Hämäläinen, R.6
-
21
-
-
34249908901
-
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
-
Wernig M., Meissner A., Foreman R., Brambrink T., Ku M., Hochedlinger K., et al. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 2007, 448:318-324.
-
(2007)
Nature
, vol.448
, pp. 318-324
-
-
Wernig, M.1
Meissner, A.2
Foreman, R.3
Brambrink, T.4
Ku, M.5
Hochedlinger, K.6
-
22
-
-
78649467088
-
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells
-
Loewer S., Cabili M.N., Guttman M., Loh Y.-H., Thomas K., Park I.H., et al. Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells. Nat Genet 2010, 42:1113-1117.
-
(2010)
Nat Genet
, vol.42
, pp. 1113-1117
-
-
Loewer, S.1
Cabili, M.N.2
Guttman, M.3
Loh, Y.-H.4
Thomas, K.5
Park, I.H.6
-
23
-
-
80052995658
-
P53, stem cells, and reprogramming tumor suppression beyond guarding the genome
-
Spike B.T., Wahl G.M. P53, stem cells, and reprogramming tumor suppression beyond guarding the genome. Genes Cancer 2011, 2:404-419.
-
(2011)
Genes Cancer
, vol.2
, pp. 404-419
-
-
Spike, B.T.1
Wahl, G.M.2
-
24
-
-
84877574727
-
Terminal differentiation and loss of tumorigenicity of human cancers via pluripotency-based reprogramming
-
Zhang X., Cruz F.D., Terry M., Remotti F., Matushansky I. Terminal differentiation and loss of tumorigenicity of human cancers via pluripotency-based reprogramming. Oncogene 2013, 32:2249-2260.
-
(2013)
Oncogene
, vol.32
, pp. 2249-2260
-
-
Zhang, X.1
Cruz, F.D.2
Terry, M.3
Remotti, F.4
Matushansky, I.5
-
25
-
-
77956278519
-
Promotion of direct reprogramming by transformation-deficient Myc
-
Nakagawa M., Takizawa N., Narita M., Ichisaka T., Yamanaka S. Promotion of direct reprogramming by transformation-deficient Myc. Proc Natl Acad Sci 2010, 107:14152-14157.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 14152-14157
-
-
Nakagawa, M.1
Takizawa, N.2
Narita, M.3
Ichisaka, T.4
Yamanaka, S.5
-
26
-
-
79958292714
-
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
-
Maekawa M., Yamaguchi K., Nakamura T., Shibukawa R., Kodanaka I., Ichisaka T., et al. Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1. Nature 2011, 474:225-229.
-
(2011)
Nature
, vol.474
, pp. 225-229
-
-
Maekawa, M.1
Yamaguchi, K.2
Nakamura, T.3
Shibukawa, R.4
Kodanaka, I.5
Ichisaka, T.6
-
27
-
-
34247188473
-
Telomere and telomerase in stem cells
-
Hiyama E., Hiyama K. Telomere and telomerase in stem cells. Br J Cancer 2007, 96:1020-1024.
-
(2007)
Br J Cancer
, vol.96
, pp. 1020-1024
-
-
Hiyama, E.1
Hiyama, K.2
-
28
-
-
1042278765
-
The history of cancer epigenetics
-
Feinberg A.P., Tycko B. The history of cancer epigenetics. Nat Rev Cancer 2004, 4:143-153.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 143-153
-
-
Feinberg, A.P.1
Tycko, B.2
-
29
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones P.A., Baylin S.B. The fundamental role of epigenetic events in cancer. Nat Rev Genet 2002, 3:415-428.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
30
-
-
0037372003
-
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
-
Jaenisch R., Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003, 33:245-254.
-
(2003)
Nat Genet
, vol.33
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
31
-
-
31344442461
-
Inflammation-associated immune suppression in cancer: the roles played by cytokines chemokines and additional mediators
-
Elsevier
-
BenBaruch A. Inflammation-associated immune suppression in cancer: the roles played by cytokines chemokines and additional mediators. Seminars in cancer biology 2006, 38-52. Elsevier.
-
(2006)
Seminars in cancer biology
, pp. 38-52
-
-
BenBaruch, A.1
-
32
-
-
0037180757
-
Inflammation and cancer
-
Coussens L.M., Werb Z. Inflammation and cancer. Nature 2002, 420:860-867.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
33
-
-
80052014052
-
Inflammation meets cancer, with NF-(kappa) B as the matchmaker
-
Ben-Neriah Y., Karin M. Inflammation meets cancer, with NF-(kappa) B as the matchmaker. Nat Immunol 2011, 12:715-723.
-
(2011)
Nat Immunol
, vol.12
, pp. 715-723
-
-
Ben-Neriah, Y.1
Karin, M.2
-
34
-
-
77953463274
-
PH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity
-
De Milito A., Canese R., Marino M.L., Borghi M., Iero M., Villa A., et al. PH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity. Int J Cancer 2010, 127:207-219.
-
(2010)
Int J Cancer
, vol.127
, pp. 207-219
-
-
De Milito, A.1
Canese, R.2
Marino, M.L.3
Borghi, M.4
Iero, M.5
Villa, A.6
-
35
-
-
34948813027
-
Intracellular and extracellular tumor pH measurement in a series of patients with oral cancer
-
Becelli R., Renzi G., Morello R., Altieri F. Intracellular and extracellular tumor pH measurement in a series of patients with oral cancer. J Craniofac Surg 2007, 18:1051-1054.
-
(2007)
J Craniofac Surg
, vol.18
, pp. 1051-1054
-
-
Becelli, R.1
Renzi, G.2
Morello, R.3
Altieri, F.4
-
36
-
-
0842273229
-
Intracellular acidification abrogates the heat shock response and compromises survival of human melanoma cells 1
-
Coss R.A., Storck C.W., Daskalakis C., Berd D., Wahl M.L. Intracellular acidification abrogates the heat shock response and compromises survival of human melanoma cells 1. Mol Cancer Ther 2003, 2:383-388.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 383-388
-
-
Coss, R.A.1
Storck, C.W.2
Daskalakis, C.3
Berd, D.4
Wahl, M.L.5
-
37
-
-
0035808388
-
Intracellular acidification triggered by mitochondrial-derived hydrogen peroxide is an effector mechanism for drug-induced apoptosis in tumor cells
-
Hirpara J.L., Clément M.-V., Pervaiz S. Intracellular acidification triggered by mitochondrial-derived hydrogen peroxide is an effector mechanism for drug-induced apoptosis in tumor cells. J Biol Chem 2001, 276:514-521.
-
(2001)
J Biol Chem
, vol.276
, pp. 514-521
-
-
Hirpara, J.L.1
Clément, M.-V.2
Pervaiz, S.3
-
38
-
-
79954423356
-
Acidic stress promotes a glioma stem cell phenotype
-
Hjelmeland A.B., Wu Q., Heddleston J., Choudhary G., MacSwords J., Lathia J., et al. Acidic stress promotes a glioma stem cell phenotype. Cell Death Differ 2011, 18:829-840.
-
(2011)
Cell Death Differ
, vol.18
, pp. 829-840
-
-
Hjelmeland, A.B.1
Wu, Q.2
Heddleston, J.3
Choudhary, G.4
MacSwords, J.5
Lathia, J.6
-
39
-
-
65549166946
-
Bicarbonate increases tumor pH and inhibits spontaneous metastases
-
Robey I.F., Baggett B.K., Kirkpatrick N.D., Roe D.J., Dosescu J., Sloane B.F., et al. Bicarbonate increases tumor pH and inhibits spontaneous metastases. Cancer Res 2009, 69:2260-2268.
-
(2009)
Cancer Res
, vol.69
, pp. 2260-2268
-
-
Robey, I.F.1
Baggett, B.K.2
Kirkpatrick, N.D.3
Roe, D.J.4
Dosescu, J.5
Sloane, B.F.6
-
41
-
-
53049104709
-
Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis
-
Hu T., Liu S., Breiter D.R., Wang F., Tang Y., Sun S. Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis. Cancer Res 2008, 68:6533-6540.
-
(2008)
Cancer Res
, vol.68
, pp. 6533-6540
-
-
Hu, T.1
Liu, S.2
Breiter, D.R.3
Wang, F.4
Tang, Y.5
Sun, S.6
-
42
-
-
84893419024
-
Stimulus-triggered fate conversion of somatic cells into pluripotency
-
Obokata H., Wakayama T., Sasai Y., Kojima K., Vacanti M.P., Niwa H., et al. Stimulus-triggered fate conversion of somatic cells into pluripotency. Nature 2014, 505:641-647.
-
(2014)
Nature
, vol.505
, pp. 641-647
-
-
Obokata, H.1
Wakayama, T.2
Sasai, Y.3
Kojima, K.4
Vacanti, M.P.5
Niwa, H.6
-
43
-
-
84890523431
-
Tumor-associated vacuolar ATPase subunit promotes tumorigenic characteristics in macrophages
-
Katara G., Jaiswal M., Kulshrestha A., Kolli B., Gilman-Sachs A., Beaman K. Tumor-associated vacuolar ATPase subunit promotes tumorigenic characteristics in macrophages. Oncogene 2013, 10.1038/onc.2013.532.
-
(2013)
Oncogene
-
-
Katara, G.1
Jaiswal, M.2
Kulshrestha, A.3
Kolli, B.4
Gilman-Sachs, A.5
Beaman, K.6
-
44
-
-
79958759965
-
Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells
-
Marino M., Fais S., Djavaheri-Mergny M., Villa A., Meschini S., Lozupone F., et al. Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells. Cell Death Dis 2010, 1:e87.
-
(2010)
Cell Death Dis
, vol.1
, pp. e87
-
-
Marino, M.1
Fais, S.2
Djavaheri-Mergny, M.3
Villa, A.4
Meschini, S.5
Lozupone, F.6
-
45
-
-
34347207246
-
Proton pump inhibitors induce apoptosis of human B-cell tumors through a caspase-independent mechanism involving reactive oxygen species
-
De Milito A., Iessi E., Logozzi M., Lozupone F., Spada M., Marino M.L., et al. Proton pump inhibitors induce apoptosis of human B-cell tumors through a caspase-independent mechanism involving reactive oxygen species. Cancer Res 2007, 67:5408-5417.
-
(2007)
Cancer Res
, vol.67
, pp. 5408-5417
-
-
De Milito, A.1
Iessi, E.2
Logozzi, M.3
Lozupone, F.4
Spada, M.5
Marino, M.L.6
-
46
-
-
0034884690
-
Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone
-
Raghunand N., Mahoney B., van Sluis R., Baggett B., Gillies R.J. Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone. Neoplasia (New York, NY) 2001, 3:227.
-
(2001)
Neoplasia (New York, NY)
, vol.3
, pp. 227
-
-
Raghunand, N.1
Mahoney, B.2
van Sluis, R.3
Baggett, B.4
Gillies, R.J.5
-
47
-
-
84856849289
-
Cancer metabolism: current perspectives and future directions
-
Munoz-Pinedo C., El Mjiyad N., Ricci J. Cancer metabolism: current perspectives and future directions. Cell Death Dis 2012, 3:e248.
-
(2012)
Cell Death Dis
, vol.3
, pp. e248
-
-
Munoz-Pinedo, C.1
El Mjiyad, N.2
Ricci, J.3
-
48
-
-
84871586080
-
A molecular roadmap of reprogramming somatic cells into iPS cells
-
Polo J.M., Anderssen E., Walsh R.M., Schwarz B.A., Nefzger C.M., Lim S.M., et al. A molecular roadmap of reprogramming somatic cells into iPS cells. Cell 2012, 151:1617-1632.
-
(2012)
Cell
, vol.151
, pp. 1617-1632
-
-
Polo, J.M.1
Anderssen, E.2
Walsh, R.M.3
Schwarz, B.A.4
Nefzger, C.M.5
Lim, S.M.6
-
49
-
-
84867021989
-
Transcriptional amplification in tumor cells with elevated c-Myc
-
Lin C.Y., Lovén J., Rahl P.B., Paranal R.M., Burge C.B., Bradner J.E., et al. Transcriptional amplification in tumor cells with elevated c-Myc. Cell 2012, 151:56-67.
-
(2012)
Cell
, vol.151
, pp. 56-67
-
-
Lin, C.Y.1
Lovén, J.2
Rahl, P.B.3
Paranal, R.M.4
Burge, C.B.5
Bradner, J.E.6
-
50
-
-
40749104852
-
An extended transcriptional network for pluripotency of embryonic stem cells
-
Kim J., Chu J., Shen X., Wang J., Orkin S.H. An extended transcriptional network for pluripotency of embryonic stem cells. Cell 2008, 132:1049-1061.
-
(2008)
Cell
, vol.132
, pp. 1049-1061
-
-
Kim, J.1
Chu, J.2
Shen, X.3
Wang, J.4
Orkin, S.H.5
-
51
-
-
84872907647
-
Cellular reprogramming and cancer development
-
Semi K., Matsuda Y., Ohnishi K., Yamada Y. Cellular reprogramming and cancer development. Int J Cancer 2013, 132:1240-1248.
-
(2013)
Int J Cancer
, vol.132
, pp. 1240-1248
-
-
Semi, K.1
Matsuda, Y.2
Ohnishi, K.3
Yamada, Y.4
-
52
-
-
34247527730
-
Hypoxia-inducible factors, stem cells, and cancer
-
Keith B., Simon M.C. Hypoxia-inducible factors, stem cells, and cancer. Cell 2007, 129:465-472.
-
(2007)
Cell
, vol.129
, pp. 465-472
-
-
Keith, B.1
Simon, M.C.2
-
53
-
-
33644747418
-
HIF-2α regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth
-
Covello K.L., Kehler J., Yu H., Gordan J.D., Arsham A.M., Hu C.-J., et al. HIF-2α regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev 2006, 20:557-570.
-
(2006)
Genes Dev
, vol.20
, pp. 557-570
-
-
Covello, K.L.1
Kehler, J.2
Yu, H.3
Gordan, J.D.4
Arsham, A.M.5
Hu, C.-J.6
-
54
-
-
58949097017
-
Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha
-
Pollard P., Loenarz C., Mole D., McDonough M., Gleadle J., Schofield C., et al. Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha. Biochem J 2008, 416:387-394.
-
(2008)
Biochem J
, vol.416
, pp. 387-394
-
-
Pollard, P.1
Loenarz, C.2
Mole, D.3
McDonough, M.4
Gleadle, J.5
Schofield, C.6
-
55
-
-
45449110185
-
Hypoxia upregulates the histone demethylase JMJD1A via HIF-1
-
Wellmann S., Bettkober M., Zelmer A., Seeger K., Faigle M., Eltzschig H.K., et al. Hypoxia upregulates the histone demethylase JMJD1A via HIF-1. Biochem Biophys Res Commun 2008, 372:892-897.
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 892-897
-
-
Wellmann, S.1
Bettkober, M.2
Zelmer, A.3
Seeger, K.4
Faigle, M.5
Eltzschig, H.K.6
-
56
-
-
73549088729
-
Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1α enhances hypoxic gene expression and tumor growth
-
Krieg A.J., Rankin E.B., Chan D., Razorenova O., Fernandez S., Giaccia A.J. Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1α enhances hypoxic gene expression and tumor growth. Mol Cell Biol 2010, 30:344-353.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 344-353
-
-
Krieg, A.J.1
Rankin, E.B.2
Chan, D.3
Razorenova, O.4
Fernandez, S.5
Giaccia, A.J.6
-
57
-
-
70350353348
-
Role of hypoxia-inducible factors in epigenetic regulation via histone demethylases
-
Yang J., Ledaki I., Turley H., Gatter K.C., Montero J.C.M., Li J.L., et al. Role of hypoxia-inducible factors in epigenetic regulation via histone demethylases. Ann N Y Acad Sci 2009, 1177:185-197.
-
(2009)
Ann N Y Acad Sci
, vol.1177
, pp. 185-197
-
-
Yang, J.1
Ledaki, I.2
Turley, H.3
Gatter, K.C.4
Montero, J.C.M.5
Li, J.L.6
-
59
-
-
40849139208
-
Epigenetics in cancer
-
Esteller M. Epigenetics in cancer. N Engl J Med 2008, 358:1148-1159.
-
(2008)
N Engl J Med
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
60
-
-
77449150586
-
The p53 core domain is a molten globule at low pH functional implications of a partially unfolded structure
-
Bom A.P.D.A., Freitas M.S., Moreira F.S., Ferraz D., Sanches D., Gomes A.M., et al. The p53 core domain is a molten globule at low pH functional implications of a partially unfolded structure. J Biol Chem 2010, 285:2857-2866.
-
(2010)
J Biol Chem
, vol.285
, pp. 2857-2866
-
-
Bom, A.P.D.A.1
Freitas, M.S.2
Moreira, F.S.3
Ferraz, D.4
Sanches, D.5
Gomes, A.M.6
-
61
-
-
84865649026
-
Effects of extracellular lactate on production of reactive oxygen species by equine polymorphonuclear leukocytes in vitro
-
Echigoya Y., Morita S., Itou T., Sakai T. Effects of extracellular lactate on production of reactive oxygen species by equine polymorphonuclear leukocytes in vitro. Am J Vet Res 2012, 73:1290-1298.
-
(2012)
Am J Vet Res
, vol.73
, pp. 1290-1298
-
-
Echigoya, Y.1
Morita, S.2
Itou, T.3
Sakai, T.4
-
62
-
-
84870587105
-
Reactive oxygen species regulate ERBB2 and ERBB3 expression via miR-199a/125b and DNA methylation
-
He J., Xu Q., Jing Y., Agani F., Qian X., Carpenter R., et al. Reactive oxygen species regulate ERBB2 and ERBB3 expression via miR-199a/125b and DNA methylation. EMBO Rep 2012, 13:1116-1122.
-
(2012)
EMBO Rep
, vol.13
, pp. 1116-1122
-
-
He, J.1
Xu, Q.2
Jing, Y.3
Agani, F.4
Qian, X.5
Carpenter, R.6
-
63
-
-
57249103576
-
Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter
-
Lim S.-O., Gu J.-M., Kim M.S., Kim H.-S., Park Y.N., Park C.K., et al. Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter. Gastroenterol 2008, 135(2128-2140):e2128.
-
(2008)
Gastroenterol
, vol.135
, Issue.2128-2140
, pp. e2128
-
-
Lim, S.-O.1
Gu, J.-M.2
Kim, M.S.3
Kim, H.-S.4
Park, Y.N.5
Park, C.K.6
-
64
-
-
77952959173
-
Downregulation of catalase by reactive oxygen species via hypermethylation of CpG island II on the catalase promoter
-
Min J.Y., Lim S.-O., Jung G. Downregulation of catalase by reactive oxygen species via hypermethylation of CpG island II on the catalase promoter. FEBS Lett 2010, 584:2427-2432.
-
(2010)
FEBS Lett
, vol.584
, pp. 2427-2432
-
-
Min, J.Y.1
Lim, S.-O.2
Jung, G.3
-
65
-
-
33746149756
-
Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice
-
Rofstad E.K., Mathiesen B., Kindem K., Galappathi K. Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice. Cancer Res 2006, 66:6699-6707.
-
(2006)
Cancer Res
, vol.66
, pp. 6699-6707
-
-
Rofstad, E.K.1
Mathiesen, B.2
Kindem, K.3
Galappathi, K.4
-
66
-
-
84892712568
-
In vivo proton-electron double-resonance imaging of extracellular tumor pH using an advanced nitroxide probe
-
Samouilov A., Efimova O.V., Bobko A.A., Sun Z., Petryakov S., Eubank T.D., et al. In vivo proton-electron double-resonance imaging of extracellular tumor pH using an advanced nitroxide probe. Anal Chem 2013, 86(2):1045-1052.
-
(2013)
Anal Chem
, vol.86
, Issue.2
, pp. 1045-1052
-
-
Samouilov, A.1
Efimova, O.V.2
Bobko, A.A.3
Sun, Z.4
Petryakov, S.5
Eubank, T.D.6
-
67
-
-
0037068353
-
DNA methylation in cancer: too much, but also too little
-
Ehrlich M. DNA methylation in cancer: too much, but also too little. Oncogene 2002, 21:5400-5413.
-
(2002)
Oncogene
, vol.21
, pp. 5400-5413
-
-
Ehrlich, M.1
-
68
-
-
84918793677
-
Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis
-
Hu T., Liu S., Breiter D., Wang F., Tang Y., Sun S. Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis. Klin Padiatr 2012, 224:A9.
-
(2012)
Klin Padiatr
, vol.224
, pp. A9
-
-
Hu, T.1
Liu, S.2
Breiter, D.3
Wang, F.4
Tang, Y.5
Sun, S.6
-
69
-
-
38349004471
-
Oct-4 is critical for survival/antiapoptosis of murine embryonic stem cells subjected to stress: effects associated with Stat3/survivin
-
Guo Y., Mantel C., Hromas R.A., Broxmeyer H.E. Oct-4 is critical for survival/antiapoptosis of murine embryonic stem cells subjected to stress: effects associated with Stat3/survivin. Stem Cells 2008, 26:30-34.
-
(2008)
Stem Cells
, vol.26
, pp. 30-34
-
-
Guo, Y.1
Mantel, C.2
Hromas, R.A.3
Broxmeyer, H.E.4
-
70
-
-
84859496473
-
Cell growth arrest and apoptosis induced by Oct4 or Nanog knockdown in mouse embryonic stem cells: a possible role of Trp53
-
Chen T., Du J., Lu G. Cell growth arrest and apoptosis induced by Oct4 or Nanog knockdown in mouse embryonic stem cells: a possible role of Trp53. Mol Biol Rep 2012, 39:1855-1861.
-
(2012)
Mol Biol Rep
, vol.39
, pp. 1855-1861
-
-
Chen, T.1
Du, J.2
Lu, G.3
-
71
-
-
0032480226
-
DNA hypomethylation leads to elevated mutation rates
-
Chen R.Z., Pettersson U., Beard C., Jackson-Grusby L., Jaenisch R. DNA hypomethylation leads to elevated mutation rates. Nature 1998, 395:89-93.
-
(1998)
Nature
, vol.395
, pp. 89-93
-
-
Chen, R.Z.1
Pettersson, U.2
Beard, C.3
Jackson-Grusby, L.4
Jaenisch, R.5
-
72
-
-
0242584454
-
Chromosomal instability and tumors promoted by DNA hypomethylation
-
Eden A., Gaudet F., Waghmare A., Jaenisch R. Chromosomal instability and tumors promoted by DNA hypomethylation. Science 2003, 300:455.
-
(2003)
Science
, vol.300
, pp. 455
-
-
Eden, A.1
Gaudet, F.2
Waghmare, A.3
Jaenisch, R.4
|