Hepatic Farnesoid X-Receptor isoforms α2 and α4 differentially modulate bile salt and lipoprotein metabolism in mice

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Boesjes, Marije ^a   Bloks, Vincent W ^a   Hageman, Jurre ^a   Bos, Trijnie ^a   Van Dijk, Theo H ^a   Havinga, Rick ^a   Wolters, Henk ^a   Jonker, Johan W ^a   Kuipers, Folkert ^a   Groen, Albert K ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILE SALT; CELL NUCLEUS RECEPTOR; CHOLESTEROL; CYP8B1 PROTEIN; FARNESOID X RECEPTOR; FARNESOID X RECEPTOR ALPHA2; FARNESOID X RECEPTOR ALPHA4; ISOPROTEIN; LIPID; LIPOPROTEIN; PARVOVIRUS VECTOR; PROTEIN; STEROL; UNCLASSIFIED DRUG; BILE ACID; CELL RECEPTOR; FARNESOID X-ACTIVATED RECEPTOR;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENTEROHEPATIC CIRCULATION; EXON; GENE EXPRESSION PROFILING; HYDROPHOBICITY; INSULIN SENSITIVITY; INTESTINE ABSORPTION; LIPID BLOOD LEVEL; LIPID METABOLISM; LIPOPROTEIN METABOLISM; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; STEROL EXCRETION; WILD TYPE; ANIMAL; C57BL MOUSE; GENETICS; KNOCKOUT MOUSE; LIVER; METABOLISM;

MUS;

ANIMALS; BILE ACIDS AND SALTS; LIPID METABOLISM; LIPOPROTEINS; LIVER; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN ISOFORMS; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

EID: 84918518673     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0115028     Document Type: Article

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