Differential activation of the human farnesoid X receptor depends on the pattern of expressed isoforms and the bile acid pool composition

Biochemical Pharmacology

Volumn 86, Issue 7, 2013, Pages 926-939

  Vaquero, Javier ^a   Monte, Maria J ^a,d   Dominguez, Mercedes ^b   Muntané, Jordi ^c,d   Marin, Jose J G ^a,d  

^a UNIVERSITY OF SALAMANCA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^d INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

Glycoconjugated bile acids; Ileum; Liver; Nuclear receptor; Tauroconjugated bile acids

Indexed keywords

3 [2 [2 CHLORO 4 [3 (2,6 DICHLOROPHENYL) 5 ISOPROPYL 4 ISOXAZOLYLMETHOXY]PHENYL]VINYL]BENZOIC ACID; BILE ACID; FARNESOID X RECEPTOR; FARNESOID X RECEPTOR ALPHA 1; FARNESOID X RECEPTOR ALPHA 2; GLYCINE; MESSENGER RNA; TAURINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; GENE ACTIVATION; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTESTINE CELL; LIVER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; UPREGULATION;

ACA; ALLOCHOLIC ACID; BA; BILE ACID; BILE SALT EXPORT PUMP; BSEP; CA; CDCA; CHENODEOXYCHOLIC ACID; CHOLIC ACID; DCA; DEOXYCHOLIC ACID; FARNESOID X RECEPTOR; FGF; FIBROBLAST GROWTH FACTOR; FXR; GCDCA; GLYCOCHENODEOXYCHOLIC ACID; GLYCOCONJUGATED BILE ACIDS; IBABP; ILEAL BILE ACID BINDING PROTEIN; ILEUM; LCA; LITHOCHOLIC ACID; LIVER; NUCLEAR RECEPTOR; OATP; ORGANIC ANION TRANSPORTER POLIPEPTIDE; ORGANIC SOLUTE TRANSPORTER; OST; RETINOID X RECEPTOR; RXR; SHP; SMALL HETERODIMER PARTNER; TAUROCHENODEOXYCHOLIC ACID; TAUROCONJUGATED BILE ACIDS; TCDCA; UDCA; URSODEOXYCHOLIC ACID;

BILE ACIDS AND SALTS; CELLS, CULTURED; GLYCINE; HEPATOCYTES; HUMANS; INTESTINES; ISOXAZOLES; KIDNEY; LIVER; ORGAN SPECIFICITY; PROTEIN ISOFORMS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TAURINE;

EID: 84884703484     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.07.022     Document Type: Article

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