Human FXR regulates SHP expression through direct binding to an LRH-1 binding site, independent of an IR-1 and LRH-1

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Hoeke, Martijn O ^a   Heegsma, Janette ^a   Hoekstra, Mark ^a   Moshage, Han ^a   Faber, Klaas Nico ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALITRETINOIN; CHENODEOXYCHOLIC ACID; FARNESOID X RECEPTOR; LIVER RECEPTOR HOMOLOG 1; MESSENGER RNA; PROTEIN TYROSINE PHOSPHATASE SHP 1; RETINOID X RECEPTOR ALPHA;

ARTICLE; BINDING SITE; CELL STRAIN HEK293; CELL STRAIN HEPG2; GENE MUTATION; HUMAN; IN VITRO STUDY; INVERTED REPEAT; POLYMERASE CHAIN REACTION; PROTEIN BINDING; RECEPTOR BINDING; RNA ISOLATION;

BINDING SITES; BLOTTING, WESTERN; GENE EXPRESSION REGULATION; HEK293 CELLS; HEP G2 CELLS; HUMANS; IMMUNOPRECIPITATION; INVERTED REPEAT SEQUENCES; LUCIFERASES; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RESPONSE ELEMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA-BINDING PROTEINS;

EID: 84894612360     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088011     Document Type: Article

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