Toxicogenomics in vitro as an alternative tool for safety evaluation of petroleum substances and PAHs with regard to prenatal developmental toxicity

Toxicology in Vitro

Volumn 29, Issue 2, 2015, Pages 299-307

  Tsitou, Polyxeni ^a,b   Heneweer, Marjoke ^a   Boogaard, Peter J ^a  

^a SHELL GLOBAL SOLUTIONS INTERNATIONAL B V   (United States)

^b WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Developmental toxicity; Oil; Polycyclic aromatic hydrocarbons; REACH; Reprotoxicity; Toxicogenomics

Indexed keywords

BIOLOGICAL MARKER; PETROLEUM; POLYCYCLIC AROMATIC HYDROCARBON;

ANIMAL EMBRYO; BONE DEVELOPMENT; CHEMICAL STRUCTURE; DEVELOPMENTAL TOXICITY; EUROPEAN UNION; EXPOSURE; FOX GENE; GENE; GENOMICS; HOX GENE; HUMAN; IN VITRO STUDY; MOLECULAR WEIGHT; MULTIGENE FAMILY; NONHUMAN; PAX GENE; PRENATAL DEVELOPMENT; REVIEW; SAFETY; SHH GENE; TISSUE SPECIFICITY; TOXICITY TESTING; TOXICOGENOMICS; TOXICOLOGY; ZEBRA FISH; ANIMAL; ANIMAL TESTING ALTERNATIVE; EMBRYO DEVELOPMENT; TOXICOGENETICS;

ANIMALIA; DANIO RERIO;

ANIMAL USE ALTERNATIVES; ANIMALS; EMBRYONIC DEVELOPMENT; HUMANS; PETROLEUM; POLYCYCLIC HYDROCARBONS, AROMATIC; TOXICOGENETICS;

EID: 84917709118     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2014.11.005     Document Type: Review

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