Phenanthrene causes ocular developmental toxicity in zebrafish embryos and the possible mechanisms involved

Journal of Hazardous Materials

Volumn 261, Issue , 2013, Pages 172-180

  Huang, Lixing ^a   Wang, Chonggang ^a   Zhang, Youyu ^a   Wu, Meifang ^a   Zuo, Zhenghong ^a  

^a XIAMEN UNIVERSITY   (China)

Author keywords

AhR Zeb1 Mitf Pax6; Ocular developmental toxicity; Phenanthrene; Zebrafish

Indexed keywords

AHR/ZEB1/MITF/PAX6; ARYL HYDROCARBON RECEPTOR; DEVELOPMENTAL TOXICITY; ENVIRONMENTAL CONCENTRATION; MORPHOLOGICAL CHANGES; PHENANTHRENE; POLYCYCLIC AROMATIC HYDROCARBONS (PAHS); ZEBRAFISH;

CELL DEATH; CELL PROLIFERATION; DEFECTS; TOXICITY;

ANTHRACENE;

AROMATIC HYDROCARBON RECEPTOR; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; PHENANTHRENE; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR ZEB1;

BIOLOGICAL DEVELOPMENT; CYPRINID; ECOTOXICOLOGY; EMBRYO; EYE; GENE EXPRESSION; MORPHOLOGY; PAH; PHENANTHRENE; POLLUTION EFFECT; POLLUTION EXPOSURE; TOXICITY TEST;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DEVELOPMENTAL TOXICITY; EMBRYO; EYE TOXICITY; FEMALE; GROWTH RETARDATION; NONHUMAN; PROTEIN EXPRESSION; VISUAL DISORDER; ZEBRA FISH;

AHR/ZEB1/MITF/PAX6; OCULAR DEVELOPMENTAL TOXICITY; PHENANTHRENE; ZEBRAFISH;

ANIMALS; APOPTOSIS; CASPASE 3; EMBRYO, NONMAMMALIAN; EYE PROTEINS; HEP G2 CELLS; HOMEODOMAIN PROTEINS; HUMANS; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; PAIRED BOX TRANSCRIPTION FACTORS; PHENANTHRENES; RECEPTORS, ARYL HYDROCARBON; REPRESSOR PROTEINS; RETINA; TRANSCRIPTION FACTORS; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84881229421     PISSN: 03043894     EISSN: 18733336     Source Type: Journal    
DOI: 10.1016/j.jhazmat.2013.07.030     Document Type: Article

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