Rodent whole embryo culture

Methods in Molecular Biology

Volumn 889, Issue , 2012, Pages 215-237

  Harris, Craig ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Birth defects; Conceptus; Embryo; Embryotoxicity; Mice; Organogenesis; Rats; Teratogens; Visceral yolk sac; Whole embryo culture

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL GROWTH; CIRCULATION; CONTROLLED STUDY; EGG; EMBRYO; EMBRYO CULTURE; EMBRYO DEATH; GASTRULATION; HEART BEAT; IN VITRO STUDY; MOUSE; NEURAL TUBE; NEUROECTODERM; NONHUMAN; PLACENTA; PRIORITY JOURNAL; RAT; RODENT; SCORING SYSTEM; ANIMAL; ANIMAL EMBRYO; ANIMAL HUSBANDRY; CHEMISTRY; DRUG EFFECT; FEMALE; HISTOLOGY; MALE; METABOLISM; METHODOLOGY; SPRAGUE DAWLEY RAT; TOXICITY TESTING; VASCULARIZATION; YOLK SAC;

PROTEIN;

ANIMAL HUSBANDRY; ANIMALS; EMBRYO CULTURE TECHNIQUES; EMBRYO, MAMMALIAN; FEMALE; MALE; MICE; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RESEARCH DESIGN; TOXICITY TESTS; YOLK SAC;

EID: 84866522906     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-867-2_13     Document Type: Article

References (16)

1. New DA (1966) Development of rat embryos cultured in blood sera. J Reprod Fertil 12:509-524
2. New DA (1967) Development of explanted rat embryos in circulating medium. J Embryol Exp Morphol 17:513-525
3. New DA, Coppola PT, Terry S (1973) Culture of explanted rat embryos in rotating tubes. J Reprod Fertil 35:135-138
4. New DAT (1978) Whole-embryo culture and the study of mammalian embryos during organogenesis. Biol Rev 53:81-122
5. Webster WS, Brown-Woodman PDC, Ritchie HE (1997) A review of the contribution of whole embryo culture to the determination of hazard and risk in teratogenicity testing. Int J Dev Biol 41:329-335
6. Kochhar DM (1980) In vitro testing of terato-genic agents using mammalian embryos. Teratog Carcinog Mutagen 1:63-74
7. Janer G, Verhoef A, Gilsing HD, Piersma AH (2008) Use of the rat postimplantation embryo culture to assess the embryotoxic potency within a chemical category and to identify toxic metabolites. Toxicol In Vitro 22:1797-1805
8. Schardein JL (1993) Chemically induced birth defects, 2nd edn. Marcel Dekker, New York, NY
9. Harris C (1997) In vivo and in vitro models for the study of developmental toxicity. In: Sipes I, McQueen CA, GandolfiAJ (eds) Comprehensive toxicology, vol 10, sec. 3, chap. 10.47: Developmental toxicology (Harris C, sec. ed.), Elsevier Science: Oxford, pp. 607-620
10. Harris C, Hansen JM (2005) In vitro methods for the study of mechanisms in developmental toxicity. In: Hood R (ed) Developmental and reproductive toxicology: a practical approach. CRC, Taylor and Francis, Boca Raton, FL, pp 647-695
11. Ellis-Hutchings RG, Carney EW (2010) Whole embryo culture: a "New" technique that enabled decades of mechanistic discoveries. Birth Defects Res B 89:304-312
12. Brown NA, Fabro S (1981) Quantitation of rat embryonic development in vitro: a morphological scoring system. Teratology 24:65-78
13. van Maele-Fabry G, Delhaise F, Picard JJ (1992) Evolution of the developmental scores of sixteen morphological features in mouse embryos displaying 0 to 30 somites. Int J Dev Biol 36:161-167
14. van Maele-Fabry G, Delhaise F, Picard JJ (1990) Morphogenesis and quanti fication of the development of post-implantation mouse embryos. Toxicol In Vitro 4:149-156
15. Zager RA, Burkhart KM, Conrad DS (1999) Iso flurane alters proximal tubular cell susceptibility to toxic and hypoxic forms of attack. Kidney Int 35:148-159
16. Lochhead KMED, Kharasch EH, Zager RA (1997) Spectrum and subcellular determinants of fluorinated anesthetic-mediated proximal tubular injury. Am J Pathol 150:2209-2221