Reproductive toxicants have a threshold of adversity

Critical Reviews in Toxicology

Volumn 41, Issue 6, 2011, Pages 545-554

  Piersma, Aldert H ^a,b   Hernandez, Lya G ^a   Van Benthem, Jan ^a   Muller, J J Andre ^a   Van Leeuwen, F X Rolaf ^a   Vermeire, Theo G ^a   Van Raaij, Marcel T M ^a  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

ADME; ALARA; benchmark dose; classification and labeling; dose response; genotoxic carcinogen; homeostasis; linear extrapolation; Margin of Exposure (MoE); reproductive cycle; reproductive toxicology; risk assessment

Indexed keywords

2 AMINO 1 METHYL 6 PHENOLIMIDAZO[4,5 B]PYRIDINE; ACETALDEHYDE; CARCINOGEN; DIETHYLNITROSAMINE; DIETHYLSTILBESTROL; ETHYLNITROSOUREA; MESYLIC ACID ETHYL ESTER; METHYLMERCURY; METHYLMETHANE SULFONATE; METHYLNITROSOUREA; THALIDOMIDE; UNCLASSIFIED DRUG; VINYL ACETATE; VITAMIN;

CARCINOGENESIS; DNA DAMAGE; DOSE RESPONSE; GENOTOXICITY; HOMEOSTASIS; HUMAN; NONHUMAN; PHYSICAL CHEMISTRY; POLLUTANT; REPRODUCTIVE TOXICITY; REVIEW; RISK ASSESSMENT; TOXICOKINETICS;

ANIMALS; CARCINOGENS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDPOINT DETERMINATION; HAZARDOUS SUBSTANCES; HUMANS; MUTAGENS; RISK ASSESSMENT; TERATOGENS; THRESHOLD LIMIT VALUES;

EID: 79958800902     PISSN: 10408444     EISSN: 15476898     Source Type: Journal    
DOI: 10.3109/10408444.2011.554794     Document Type: Review

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