Chromatin-mediated depression of fractionation performance on electronegative multimodal chromatography media, its prevention, and ramifications for purification of immunoglobulin G

Journal of Chromatography A

Volumn 1374, Issue , 2014, Pages 145-155

  Gagnon, Pete ^a   Nian, Rui ^a   Tan, Lihan ^a   Cheong, Jason ^a   Yeo, Veronica ^a   Yang, Yuansheng ^a   Gan, Hui Theng ^a  

^a AGENCY FOR SCIENCE   (Singapore)

Author keywords

Aggregates; Capacity; Chromatin; IgG; Leaching; Multimodal

Indexed keywords

AGGREGATES; CELL CULTURE; CHROMATOGRAPHY; CHROMOSOMES; DNA; FATTY ACIDS; LEACHING; PURIFICATION; RECOVERY; SODIUM CHLORIDE; SODIUM HYDROXIDE; VIRUSES;

CAPACITY; CHROMATIN; HETERO-AGGREGATES; HOST CELL PROTEIN; MULTI-MODAL; MULTIMODAL CHROMATOGRAPHIES; NUCLEOSOMAL ARRAYS; PURIFICATION PROCESS;

PROTEINS;

ADSORBENT; DNA; FATTY ACID; HISTONE; IMMUNOGLOBULIN G; PROTEIN A; SODIUM CHLORIDE; VIRUS ENVELOPE PROTEIN; CHROMATIN; STAPHYLOCOCCUS PROTEIN A;

ADSORPTION CHROMATOGRAPHY; ARTICLE; CELL AGGREGATION; CHROMATIN; CONTROLLED STUDY; FRACTIONATION; PARTICLE SIZE; PROTEIN PURIFICATION; AFFINITY CHROMATOGRAPHY; ANIMAL; CELL LINE; CHEMISTRY; ELECTRON; ISOLATION AND PURIFICATION; MOLECULAR WEIGHT; PROCEDURES;

ANIMALS; CELL LINE; CHROMATIN; CHROMATOGRAPHY, AFFINITY; DNA; ELECTRONS; IMMUNOGLOBULIN G; MOLECULAR WEIGHT; PARTICLE SIZE; STAPHYLOCOCCAL PROTEIN A;

EID: 84916199227     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2014.11.052     Document Type: Article

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