Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia

Journal of Clinical Investigation

Volumn 124, Issue 12, 2014, Pages 5175-5190

  Cotter, David G ^a,b   Ercal, Baris ^a   Huang, Xiaojing ^a,c   Leid, Jamison M ^a   D'Avignon, D André ^c   Graham, Mark J ^d   Dietzen, Dennis J ^b   Brunt, Elizabeth M ^b   Patti, Gary J ^b,c   Crawford, Peter A ^a,b  

^a BURNHAM INSTITUTE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WASHINGTON UNIVERSITY   (United States)

^d ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A; ANTISENSE OLIGONUCLEOTIDE; COENZYME A; CYSTEINE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; PANTOTHENIC ACID; PYRUVIC ACID; FAT INTAKE; GLUCOSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CITRIC ACID CYCLE; CONTROLLED STUDY; DIETARY INTAKE; ENZYME METABOLISM; FATTY LIVER; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HYPERGLYCEMIA; INFLAMMATION; KETOGENESIS; LIPID DIET; LIPOGENESIS; LIVER CELL DAMAGE; LIVER INJURY; METABOLISM; METABOLITE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; ADVERSE EFFECTS; ANIMAL; CHEMICALLY INDUCED; DEFICIENCY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG EFFECTS; FAT INTAKE; GENETICS; HYPOGLYCEMIA; INBORN ERROR OF METABOLISM; MALE; MUTANT MOUSE STRAIN; PATHOLOGY;

ACYL COENZYME A; ANIMALS; CITRIC ACID CYCLE; DIETARY FATS; GLUCONEOGENESIS; GLUCOSE; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; HYPERGLYCEMIA; HYPOGLYCEMIA; MALE; METABOLISM, INBORN ERRORS; MICE; MICE, MUTANT STRAINS; MITOCHONDRIAL DISEASES; NON-ALCOHOLIC FATTY LIVER DISEASE;

EID: 84915820736     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI76388     Document Type: Article

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