Human HMGCS2 regulates mitochondrial fatty acid oxidation and FGF21 expression in HepG2 cell line

Journal of Biological Chemistry

Volumn 286, Issue 23, 2011, Pages 20423-20430

  Vilà Brau, Anna ^a   De Sousa Coelho, Ana Luísa ^a   Mayordomo, Cristina ^a   Haro, Diego ^a   Marrero, Pedro F ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CULTURE MEDIUM; CULTURED CELL; EXPRESSION PATTERNS; FATTY ACID OXIDATION; FEED-FORWARD; FIBROBLAST GROWTH FACTOR; HEPG2 CELL LINE; HEPG2 CELLS; HYDROXYMETHYLGLUTARYL; IN-VIVO; INACTIVE MUTANTS; KETONE BODIES; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; SIRTUIN; SYNTHASES; TARGET GENES; WILD-TYPE ENZYMES;

CELL CULTURE; FATTY ACIDS; KETONES; ORGANIC COMPOUNDS; OXIDATION;

GENE EXPRESSION;

ACETOACETIC ACID; FIBROBLAST GROWTH FACTOR 21; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE 2; KETONE BODY; MESSENGER RNA; MUTANT PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; SIRTUIN 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL METABOLISM; CELL STRAIN HEPG2; CONTROLLED STUDY; CULTURE MEDIUM; DIET RESTRICTION; DOWN REGULATION; ENZYME ACTIVITY; ENZYME REGULATION; FATTY ACID OXIDATION; GENE TARGETING; HUMAN; HUMAN CELL; KETOGENESIS; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; RNA INTERFERENCE; WILD TYPE;

AMINO ACID SUBSTITUTION; ANIMALS; FASTING; FATTY ACIDS; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION; HEP G2 CELLS; HUMANS; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; KETONE BODIES; MICE; MICE, KNOCKOUT; MUTATION, MISSENSE; OXIDATION-REDUCTION; PPAR ALPHA; SIRTUIN 1;

EID: 79957992155     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.235044     Document Type: Article

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