-
1
-
-
0032713688
-
Brain function in the elderly: Role of vitamin B12 and folate
-
Weir DG, Scott JM (1999) Brain function in the elderly: Role of vitamin B12 and folate. Br Med Bull 55, 669-682.
-
(1999)
Br Med Bull
, vol.55
, pp. 669-682
-
-
Weir, D.G.1
Scott, J.M.2
-
2
-
-
8344273321
-
Cobalamin transport proteins and their cell-surface receptors
-
Seetharam B, Yammani RR (2003) Cobalamin transport proteins and their cell-surface receptors. Expert Rev Mol Med 5, 1-18.
-
(2003)
Expert Rev Mol Med
, vol.5
, pp. 1-18
-
-
Seetharam, B.1
Yammani, R.R.2
-
3
-
-
0342424746
-
Methylmalonic acid induces excitotoxic neuronal damage in vitro
-
Kolker S, Ahlemeyer B, Krieglstein J, Hoffmann GF (2000) Methylmalonic acid induces excitotoxic neuronal damage in vitro. J Inherit Metab Dis 23, 355-358.
-
(2000)
J Inherit Metab Dis
, vol.23
, pp. 355-358
-
-
Kolker, S.1
Ahlemeyer, B.2
Krieglstein, J.3
Hoffmann, G.F.4
-
4
-
-
0038387939
-
Homocysteine and Alzheimer's disease
-
Morris MS (2003) Homocysteine and Alzheimer's disease. Lancet Neurol 2, 425-428.
-
(2003)
Lancet Neurol
, vol.2
, pp. 425-428
-
-
Morris, M.S.1
-
5
-
-
84888161072
-
Therapeutic targeting of autophagy in disease: Biology and pharmacology
-
Cheng Y, Ren X, Hait WN, Yang JM (2013) Therapeutic targeting of autophagy in disease: Biology and pharmacology. Pharmacol Rev 65, 1162-1197.
-
(2013)
Pharmacol Rev
, vol.65
, pp. 1162-1197
-
-
Cheng, Y.1
Ren, X.2
Hait, W.N.3
Yang, J.M.4
-
6
-
-
0021892612
-
Defect in vitamin B12 release from lysosomes: Newly described inborn error of vitamin B12 metabolism
-
Rosenblatt DS, Hosack A, Matiaszuk NV, Cooper BA, Laframboise R (1985) Defect in vitamin B12 release from lysosomes: Newly described inborn error of vitamin B12 metabolism. Science 228, 1319-1321.
-
(1985)
Science
, vol.228
, pp. 1319-1321
-
-
Rosenblatt, D.S.1
Hosack, A.2
Matiaszuk, N.V.3
Cooper, B.A.4
Laframboise, R.5
-
7
-
-
84866937421
-
Mutations in ABCD4 cause a newinborn error of vitamin B12 metabolism
-
Coelho D, Kim JC, Miousse IR, Fung S, du Moulin M, Buers I, Suormala T, Burda P, Frapolli M, Stucki M, Nurnberg P, Thiele H, Robenek H, HohneW, Longo N, Pasquali M, Mengel E,Watkins D, Shoubridge EA, Majewski J, Rosenblatt DS, Fowler B, Rutsch F, Baumgartner MR (2012) Mutations in ABCD4 cause a newinborn error of vitamin B12 metabolism. Nat Genet 44, 1152-1155.
-
(2012)
Nat Genet
, vol.44
, pp. 1152-1155
-
-
Coelho, D.1
Kim, J.C.2
Miousse, I.R.3
Fung, S.4
Du Moulin, M.5
Buers, I.6
Suormala, T.7
Burda, P.8
Frapolli, M.9
Stucki, M.10
Nurnberg, P.11
Thiele, H.12
Robenek, H.13
Hohne, W.14
Longo, N.15
Pasquali, M.16
Mengel, E.17
Watkins, D.18
Shoubridge, E.A.19
Majewski, J.20
Rosenblatt, D.S.21
Fowler, B.22
Rutsch, F.23
Baumgartner, M.R.24
more..
-
8
-
-
77954565111
-
Insights into lysosomal cobalamin trafficking: Lessons learned from cblF disease
-
Gailus S, HohneW, Gasnier B, Nurnberg P, Fowler B, Rutsch F (2010) Insights into lysosomal cobalamin trafficking: Lessons learned from cblF disease. J Mol Med 88, 459-466.
-
(2010)
J Mol Med
, vol.88
, pp. 459-466
-
-
Gailus, S.1
Hohne, W.2
Gasnier, B.3
Nurnberg, P.4
Fowler, B.5
Rutsch, F.6
-
11
-
-
84883137463
-
Alzheimer's disease
-
De-Paula VJ, Radanovic M, Diniz BS, Forlenza OV (2012) Alzheimer's disease. Subcell Biochem 65, 329-352.
-
(2012)
Subcell Biochem
, vol.65
, pp. 329-352
-
-
De-Paula, V.J.1
Radanovic, M.2
Diniz, B.S.3
Forlenza, O.V.4
-
12
-
-
5344240284
-
Amyloid-beta precursor protein processing in neurodegeneration
-
WilquetV, De StrooperB(2004) Amyloid-beta precursor protein processing in neurodegeneration. Curr Opin Neurobiol 14, 582-588.
-
(2004)
Curr Opin Neurobiol
, vol.14
, pp. 582-588
-
-
Wilquet, V.1
De Strooper, B.2
-
13
-
-
38349046973
-
Autophagy, amyloidogenesis and Alzheimer disease
-
Nixon RA (2007) Autophagy, amyloidogenesis and Alzheimer disease. J Cell Sci 120, 4081-4091.
-
(2007)
J Cell Sci
, vol.120
, pp. 4081-4091
-
-
Nixon, R.A.1
-
14
-
-
0035110055
-
Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease
-
Ditaranto K, Tekirian TL, Yang AJ (2001) Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease. Neurobiol Dis 8, 19-31.
-
(2001)
Neurobiol Dis
, vol.8
, pp. 19-31
-
-
Ditaranto, K.1
Tekirian, T.L.2
Yang, A.J.3
-
15
-
-
50949097728
-
Oligomer-specific Abeta toxicity in cell models is mediated by selective uptake
-
Chafekar SM, Baas F, Scheper W (2008) Oligomer-specific Abeta toxicity in cell models is mediated by selective uptake. Biochim Biophys Acta 1782, 523-531.
-
(2008)
Biochim Biophys Acta
, vol.1782
, pp. 523-531
-
-
Chafekar, S.M.1
Baas, F.2
Scheper, W.3
-
16
-
-
58149173970
-
Oxidative stress induces macroautophagy of amyloid beta-protein and ensuing apoptosis
-
Zheng L, Kagedal K, Dehvari N, Benedikz E, Cowburn R, Marcusson J, Terman A (2009) Oxidative stress induces macroautophagy of amyloid beta-protein and ensuing apoptosis. Free Radic Biol Med 46, 422-429.
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 422-429
-
-
Zheng, L.1
Kagedal, K.2
Dehvari, N.3
Benedikz, E.4
Cowburn, R.5
Marcusson, J.6
Terman, A.7
-
17
-
-
33645935372
-
Oxidative stress and Alzheimer disease: The autophagy connection
-
Zheng L, Marcusson J, Terman A (2006) Oxidative stress and Alzheimer disease: The autophagy connection Autophagy 2, 143-145.
-
(2006)
Autophagy
, vol.2
, pp. 143-145
-
-
Zheng, L.1
Marcusson, J.2
Terman, A.3
-
18
-
-
33744462609
-
Oxidative stress induces intralysosomal accumulation of Alzheimer amyloid beta-protein in cultured neuroblastoma cells
-
Zheng L, Roberg K, Jerhammar F, Marcusson J, Terman A (2006) Oxidative stress induces intralysosomal accumulation of Alzheimer amyloid beta-protein in cultured neuroblastoma cells. Ann N Y Acad Sci 1067, 248-251.
-
(2006)
Ann N y Acad Sci
, vol.1067
, pp. 248-251
-
-
Zheng, L.1
Roberg, K.2
Jerhammar, F.3
Marcusson, J.4
Terman, A.5
-
19
-
-
31344436480
-
Autophagy of amyloid beta-protein in differentiated neuroblastoma cells exposed to oxidative stress
-
Zheng L, Roberg K, Jerhammar F, Marcusson J, Terman A (2006) Autophagy of amyloid beta-protein in differentiated neuroblastoma cells exposed to oxidative stress. Neurosci Lett 394, 184-189.
-
(2006)
Neurosci Lett
, vol.394
, pp. 184-189
-
-
Zheng, L.1
Roberg, K.2
Jerhammar, F.3
Marcusson, J.4
Terman, A.5
-
20
-
-
82855181494
-
Macroautophagy-generated increase of lysosomal amyloid beta-protein mediates oxidant-induced apoptosis of cultured neuroblastoma cells
-
Zheng L, Terman A, Hallbeck M, Dehvari N, Cowburn RF, Benedikz E, Kagedal K, Cedazo-Minguez A, Marcusson J (2011) Macroautophagy-generated increase of lysosomal amyloid beta-protein mediates oxidant-induced apoptosis of cultured neuroblastoma cells. Autophagy 7, 1528-1545.
-
(2011)
Autophagy
, vol.7
, pp. 1528-1545
-
-
Zheng, L.1
Terman, A.2
Hallbeck, M.3
Dehvari, N.4
Cowburn, R.F.5
Benedikz, E.6
Kagedal, K.7
Cedazo-Minguez, A.8
Marcusson, J.9
-
21
-
-
7244234180
-
Subcellular topography of neuronal Abeta peptide in APPxPS1 transgenic mice
-
Langui D, Girardot N, El Hachimi KH, Allinquant B, Blanchard V, Pradier L, Duyckaerts C (2004) Subcellular topography of neuronal Abeta peptide in APPxPS1 transgenic mice. Am J Pathol 165, 1465-1477.
-
(2004)
Am J Pathol
, vol.165
, pp. 1465-1477
-
-
Langui, D.1
Girardot, N.2
El Hachimi, K.H.3
Allinquant, B.4
Blanchard, V.5
Pradier, L.6
Duyckaerts, C.7
-
22
-
-
56049101608
-
Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP+PS1 transgenic mouse brains
-
Amritraj A, Hawkes C, Phinney AL, Mount HT, Scott CD, Westaway D, Kar S (2009) Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP+PS1 transgenic mouse brains. Neurobiol Aging 30, 54-70.
-
(2009)
Neurobiol Aging
, vol.30
, pp. 54-70
-
-
Amritraj, A.1
Hawkes, C.2
Phinney, A.L.3
Mount, H.T.4
Scott, C.D.5
Westaway, D.6
Kar, S.7
-
23
-
-
0032526652
-
Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid Abeta1-42 pathogenesis
-
Yang AJ, Chandswangbhuvana D, Margol L, Glabe CG (1998) Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid Abeta1-42 pathogenesis. J Neurosci Res 52, 691-698.
-
(1998)
J Neurosci Res
, vol.52
, pp. 691-698
-
-
Yang, A.J.1
Chandswangbhuvana, D.2
Margol, L.3
Glabe, C.G.4
-
24
-
-
1842532328
-
The role of the endosomal/lysosomal system in amyloid-beta production and the pathophysiology of Alzheimer's disease: Reexamining the spatial paradox from a lysosomal perspective
-
Pasternak SH, Callahan JW, Mahuran DJ (2004) The role of the endosomal/lysosomal system in amyloid-beta production and the pathophysiology of Alzheimer's disease: Reexamining the spatial paradox from a lysosomal perspective. J Alzheimers Dis 6, 53-65.
-
(2004)
J Alzheimers Dis
, vol.6
, pp. 53-65
-
-
Pasternak, S.H.1
Callahan, J.W.2
Mahuran, D.J.3
-
25
-
-
84894443761
-
Perturbation of neuronal cobalamin transport by lysosomal enzyme inhibition
-
Zhao H, Ruberu K, Li H, GarnerB(2014) Perturbation of neuronal cobalamin transport by lysosomal enzyme inhibition. Biosci Rep 34(1), art:e00092.doi:10.1042/BSR20130130
-
(2014)
Biosci Rep
, vol.34
, Issue.1
-
-
Zhao, H.1
Ruberu, K.2
Li, H.3
Garner, B.4
-
26
-
-
82255194117
-
Age-related lysosomal dysfunction: An unrecognized roadblock for cobalamin trafficking
-
Zhao H, Brunk UT, Garner B (2011) Age-related lysosomal dysfunction: An unrecognized roadblock for cobalamin trafficking Cell Mol Life Sci 68, 3963-3969.
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 3963-3969
-
-
Zhao, H.1
Brunk, U.T.2
Garner, B.3
-
27
-
-
84879232282
-
Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification
-
Wolfe DM, Lee JH, Kumar A, Lee S, Orenstein SJ, Nixon RA (2013) Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification. Eur J Neurosci 37, 1949-1961.
-
(2013)
Eur J Neurosci
, vol.37
, pp. 1949-1961
-
-
Wolfe, D.M.1
Lee, J.H.2
Kumar, A.3
Lee, S.4
Orenstein, S.J.5
Nixon, R.A.6
-
28
-
-
77953913051
-
Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations
-
Lee JH, Yu WH, Kumar A, Lee S, Mohan PS, Peterhoff CM, Wolfe DM, Martinez-Vicente M, Massey AC, Sovak G, Uchiyama Y, Westaway D, Cuervo AM, Nixon RA (2010) Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations. Cell 141, 1146-1158.
-
(2010)
Cell
, vol.141
, pp. 1146-1158
-
-
Lee, J.H.1
Yu, W.H.2
Kumar, A.3
Lee, S.4
Mohan, P.S.5
Peterhoff, C.M.6
Wolfe, D.M.7
Martinez-Vicente, M.8
Massey, A.C.9
Sovak, G.10
Uchiyama, Y.11
Westaway, D.12
Cuervo, A.M.13
Nixon, R.A.14
-
29
-
-
84857765070
-
Dissociation of ERK signalling inhibition from the antiamyloidogenic action of synthetic ceramide analogues
-
Li H, Evin G, Hill AF, Hung YH, Bush AI, Garner B (2012) Dissociation of ERK signalling inhibition from the antiamyloidogenic action of synthetic ceramide analogues. Clin Sci (Lond) 122, 409-419.
-
(2012)
Clin Sci (Lond)
, vol.122
, pp. 409-419
-
-
Li, H.1
Evin, G.2
Hill, A.F.3
Hung, Y.H.4
Bush, A.I.5
Garner, B.6
-
30
-
-
84865576825
-
Amyloid-beta secretion, generation, and lysosomal sequestration in response to proteasome inhibition: Involvement of autophagy
-
Agholme L, Hallbeck M, Benedikz E, Marcusson J, Kagedal K (2012) Amyloid-beta secretion, generation, and lysosomal sequestration in response to proteasome inhibition: Involvement of autophagy. J Alzheimers Dis 31, 343-358.
-
(2012)
J Alzheimers Dis
, vol.31
, pp. 343-358
-
-
Agholme, L.1
Hallbeck, M.2
Benedikz, E.3
Marcusson, J.4
Kagedal, K.5
-
31
-
-
84878384637
-
Analysis of subcellular [57Co] cobalamin distribution in SH-SY5Y neurons and brain tissue
-
Zhao H, Ruberu K, Li H, Garner B (2013) Analysis of subcellular [57Co] cobalamin distribution in SH-SY5Y neurons and brain tissue. J Neurosci Methods 217, 67-74.
-
(2013)
J Neurosci Methods
, vol.217
, pp. 67-74
-
-
Zhao, H.1
Ruberu, K.2
Li, H.3
Garner, B.4
-
32
-
-
84874612598
-
Deletion of Abca7 increases cerebral amyloid-beta accumulation in the J20 mouse model of Alzheimer's disease
-
Kim WS, LiH, Ruberu K, Chan S, ElliottDA, LowJK, Cheng D, Karl T, Garner B (2013) Deletion of Abca7 increases cerebral amyloid-beta accumulation in the J20 mouse model of Alzheimer's disease. J Neurosci 33, 4387-4394.
-
(2013)
J Neurosci
, vol.33
, pp. 4387-4394
-
-
Kim, W.S.1
Li, H.2
Ruberu, K.3
Chan, S.4
Elliott, D.A.5
Low, J.K.6
Cheng, D.7
Karl, T.8
Garner, B.9
-
33
-
-
84896360551
-
Lysosomal sorting of amyloid-beta by the SORLA receptor is impaired by a familial Alzheimer's disease mutation
-
Caglayan S, Takagi-Niidome S, Liao F, Carlo AS, Schmidt V, Burgert T, Kitago Y, Fuchtbauer EM, Fuchtbauer A, Holtzman DM, Takagi J, Willnow TE (2014) Lysosomal sorting of amyloid-beta by the SORLA receptor is impaired by a familial Alzheimer's disease mutation. Sci Transl Med 6, 223-220.
-
(2014)
Sci Transl Med
, vol.6
, pp. 223-220
-
-
Caglayan, S.1
Takagi-Niidome, S.2
Liao, F.3
Carlo, A.S.4
Schmidt, V.5
Burgert, T.6
Kitago, Y.7
Fuchtbauer, E.M.8
Fuchtbauer, A.9
Holtzman, D.M.10
Takagi, J.11
Willnow, T.E.12
-
34
-
-
0027980319
-
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class i molecules
-
Rock KL, Gramm C, Rothstein L, Clark K, Stein R, Dick L, Hwang D, Goldberg AL (1994) Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 78, 761-771.
-
(1994)
Cell
, vol.78
, pp. 761-771
-
-
Rock, K.L.1
Gramm, C.2
Rothstein, L.3
Clark, K.4
Stein, R.5
Dick, L.6
Hwang, D.7
Goldberg, A.L.8
-
35
-
-
84878114130
-
Tau degradation: The ubiquitin-proteasome system versus the autophagy-lysosome system
-
Lee MJ, Lee JH, RubinszteinDC(2013) Tau degradation: The ubiquitin-proteasome system versus the autophagy-lysosome system. Prog Neurobiol 105, 49-59.
-
(2013)
Prog Neurobiol
, vol.105
, pp. 49-59
-
-
Lee, M.J.1
Lee, J.H.2
Rubinsztein, D.C.3
-
36
-
-
33644641768
-
Oxidative stress, accumulation of biological 'garbage', and aging
-
Terman A, Brunk UT (2006) Oxidative stress, accumulation of biological 'garbage', and aging. Antioxid Redox Signal 8, 197-204.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 197-204
-
-
Terman, A.1
Brunk, U.T.2
-
37
-
-
33749656530
-
The lysosomalmitochondrial axis theory of postmitotic aging and cell death
-
Terman A, Gustafsson B, Brunk UT (2006) The lysosomalmitochondrial axis theory of postmitotic aging and cell death. Chem Biol Interact 163, 29-37.
-
(2006)
Chem Biol Interact
, vol.163
, pp. 29-37
-
-
Terman, A.1
Gustafsson, B.2
Brunk, U.T.3
-
38
-
-
49349090381
-
Lysosomes and oxidative stress in aging and apoptosis
-
Kurz T, Terman A, Gustafsson B, Brunk UT (2008) Lysosomes and oxidative stress in aging and apoptosis. Biochim Biophys Acta 1780, 1291-1303.
-
(2008)
Biochim Biophys Acta
, vol.1780
, pp. 1291-1303
-
-
Kurz, T.1
Terman, A.2
Gustafsson, B.3
Brunk, U.T.4
-
39
-
-
0028220243
-
Lysosomal abnormalities in degenerating neurons link neuronal compromise to senile plaque development in Alzheimer disease
-
Cataldo AM, Hamilton DJ, Nixon RA (1994) Lysosomal abnormalities in degenerating neurons link neuronal compromise to senile plaque development in Alzheimer disease. Brain Res 640, 68-80.
-
(1994)
Brain Res
, vol.640
, pp. 68-80
-
-
Cataldo, A.M.1
Hamilton, D.J.2
Nixon, R.A.3
-
40
-
-
79957877931
-
Mouse transcobalamin has features resembling both human transcobalamin and haptocorrin
-
Hygum K, Lildballe DL, Greibe EH, Morkbak AL, Poulsen SS, Sorensen BS, Petersen TE, Nexo E (2011) Mouse transcobalamin has features resembling both human transcobalamin and haptocorrin. PLoS One 6, e20638.
-
(2011)
PLoS One
, vol.6
, pp. e20638
-
-
Hygum, K.1
Lildballe, D.L.2
Greibe, E.H.3
Morkbak, A.L.4
Poulsen, S.S.5
Sorensen, B.S.6
Petersen, T.E.7
Nexo, E.8
-
41
-
-
84867025624
-
Maximal load of the vitamin B12 transport system: A study on mice treated for four weeks with high-dose vitamin B12 or cobinamide
-
Lildballe DL, Mutti E, Birn H, Nexo E (2012) Maximal load of the vitamin B12 transport system: A study on mice treated for four weeks with high-dose vitamin B12 or cobinamide. PLoS One 7, e46657.
-
(2012)
PLoS One
, vol.7
, pp. e46657
-
-
Lildballe, D.L.1
Mutti, E.2
Birn, H.3
Nexo, E.4
-
42
-
-
0347126607
-
Hydroxocobalamin uptake into the cerebrospinal fluid after nasal and intravenous delivery in rats and humans
-
Van den BergMP, Merkus P, Romeijn SG,Verhoef JC, Merkus FW (2003) Hydroxocobalamin uptake into the cerebrospinal fluid after nasal and intravenous delivery in rats and humans. J Drug Target 11, 325-331.
-
(2003)
J Drug Target
, vol.11
, pp. 325-331
-
-
Van Den Berg, M.P.1
Merkus, P.2
Romeijn, S.G.3
Verhoef, J.C.4
Merkus, F.W.5
-
44
-
-
0030045552
-
Properties of the endosomal-lysosomal system in the human central nervous system: Disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease
-
Cataldo AM, Hamilton DJ, Barnett JL, Paskevich PA, Nixon RA (1996) Properties of the endosomal-lysosomal system in the human central nervous system: Disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease. J Neurosci 16, 186-199.
-
(1996)
J Neurosci
, vol.16
, pp. 186-199
-
-
Cataldo, A.M.1
Hamilton, D.J.2
Barnett, J.L.3
Paskevich, P.A.4
Nixon, R.A.5
-
45
-
-
84902261433
-
Brain pyroglutamate amyloid-beta is produced by cathepsinBand is reduced by the cysteine protease inhibitor E64d, representing a potential Alzheimer's disease therapeutic
-
Hook G, Yu J, Toneff T, Kindy M, Hook V (2014) Brain pyroglutamate amyloid-beta is produced by cathepsinBand is reduced by the cysteine protease inhibitor E64d, representing a potential Alzheimer's disease therapeutic. J Alzheimers Dis 41, 129-149.
-
(2014)
J Alzheimers Dis
, vol.41
, pp. 129-149
-
-
Hook, G.1
Yu, J.2
Toneff, T.3
Kindy, M.4
Hook, V.5
-
46
-
-
0034513748
-
Role of homocysteine, cystathionine and methylmalonic acid measurement for diagnosis of vitamin deficiency in high-aged subjects
-
Herrmann W, Schorr H, Bodis M, Knapp JP, Muller A, Stein G, Geisel J (2000) Role of homocysteine, cystathionine and methylmalonic acid measurement for diagnosis of vitamin deficiency in high-aged subjects. Eur J Clin Invest 30, 1083-1089.
-
(2000)
Eur J Clin Invest
, vol.30
, pp. 1083-1089
-
-
Herrmann, W.1
Schorr, H.2
Bodis, M.3
Knapp, J.P.4
Muller, A.5
Stein, G.6
Geisel, J.7
-
47
-
-
0037188423
-
Relationship between plasma homocysteine levels and brain atrophy in healthy elderly individuals
-
Sachdev PS, Valenzuela M, Wang XL, Looi JC, Brodaty H (2002) Relationship between plasma homocysteine levels and brain atrophy in healthy elderly individuals. Neurology 58, 1539-1541.
-
(2002)
Neurology
, vol.58
, pp. 1539-1541
-
-
Sachdev, P.S.1
Valenzuela, M.2
Wang, X.L.3
Looi, J.C.4
Brodaty, H.5
-
48
-
-
0036863956
-
Minimal hippocampal width relates to plasma homocysteine in community-dwelling older people
-
Williams JH, Pereira EA, Budge MM, Bradley KM (2002) Minimal hippocampal width relates to plasma homocysteine in community-dwelling older people. Age Ageing 31, 440-444.
-
(2002)
Age Ageing
, vol.31
, pp. 440-444
-
-
Williams, J.H.1
Pereira, E.A.2
Budge, M.M.3
Bradley, K.M.4
-
49
-
-
0037226674
-
Homocysteine and brain atrophy onMRI of non-demented elderly
-
den Heijer T, Vermeer SE, Clarke R, Oudkerk M, Koudstaal PJ, Hofman A, Breteler MM (2003) Homocysteine and brain atrophy onMRI of non-demented elderly. Brain 126, 170-175.
-
(2003)
Brain
, vol.126
, pp. 170-175
-
-
Den Heijer, T.1
Vermeer, S.E.2
Clarke, R.3
Oudkerk, M.4
Koudstaal, P.J.5
Hofman, A.6
Breteler, M.M.7
-
50
-
-
53049084486
-
Vitamin B12 status and rate of brain volume loss in community-dwelling elderly
-
Vogiatzoglou A, Refsum H, Johnston C, Smith SM, Bradley KM, de Jager C, Budge MM, Smith AD (2008) Vitamin B12 status and rate of brain volume loss in community-dwelling elderly. Neurology 71, 826-832.
-
(2008)
Neurology
, vol.71
, pp. 826-832
-
-
Vogiatzoglou, A.1
Refsum, H.2
Johnston, C.3
Smith, S.M.4
Bradley, K.M.5
De Jager, C.6
Budge, M.M.7
Smith, A.D.8
-
51
-
-
84878719283
-
Preventing Alzheimer's diseaserelated gray matter atrophy by B-vitamin treatment
-
Douaud G, Refsum H, de Jager CA, Jacoby R, Nichols TE, Smith SM, SmithAD(2013) Preventing Alzheimer's diseaserelated gray matter atrophy by B-vitamin treatment. Proc Natl Acad Sci USA 110, 9523-9528.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 9523-9528
-
-
Douaud, G.1
Refsum, H.2
De Jager, C.A.3
Jacoby, R.4
Nichols, T.E.5
Smith, S.M.6
Smith, A.D.7
-
52
-
-
84889657934
-
Serum folate, homocysteine, brain atrophy, and auto-CM system: The Treviso Dementia (TREDEM) study
-
Gallucci M, Zanardo A, Bendini M, Di Paola F, Boldrini P, Grossi E (2014) Serum folate, homocysteine, brain atrophy, and auto-CM system: The Treviso Dementia (TREDEM) study. J Alzheimers Dis 38, 581-587.
-
(2014)
J Alzheimers Dis
, vol.38
, pp. 581-587
-
-
Gallucci, M.1
Zanardo, A.2
Bendini, M.3
Di Paola, F.4
Boldrini, P.5
Grossi, E.6
-
53
-
-
43549091613
-
Association of plasma total homocysteine levels with subclinical brain injury: Cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study
-
Seshadri S, Wolf PA, Beiser AS, Selhub J, Au R, Jacques PF, Yoshita M, Rosenberg IH, D'Agostino RB, DeCarli C (2008) Association of plasma total homocysteine levels with subclinical brain injury: Cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study. Arch Neurol 65, 642-649.
-
(2008)
Arch Neurol
, vol.65
, pp. 642-649
-
-
Seshadri, S.1
Wolf, P.A.2
Beiser, A.S.3
Selhub, J.4
Au, R.5
Jacques, P.F.6
Yoshita, M.7
Rosenberg, I.H.8
D'Agostino, R.B.9
Decarli, C.10
-
54
-
-
77958567930
-
Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: A randomized controlled trial
-
Smith AD, Smith SM, de Jager CA, Whitbread P, Johnston C, Agacinski G, Oulhaj A, Bradley KM, Jacoby R, Refsum H (2010) Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: A randomized controlled trial. PLoS One 5, e12244.
-
(2010)
PLoS One
, vol.5
, pp. e12244
-
-
Smith, A.D.1
Smith, S.M.2
De Jager, C.A.3
Whitbread, P.4
Johnston, C.5
Agacinski, G.6
Oulhaj, A.7
Bradley, K.M.8
Jacoby, R.9
Refsum, H.10
-
55
-
-
84859889194
-
Cognitive and clinical outcomes of homocysteinelowering B-vitamin treatment in mild cognitive impairment: A randomized controlled trial
-
de Jager CA, Oulhaj A, Jacoby R, Refsum H, Smith AD (2012) Cognitive and clinical outcomes of homocysteinelowering B-vitamin treatment in mild cognitive impairment: A randomized controlled trial. Int J Geriatr Psychiatry 27, 592-600.
-
(2012)
Int J Geriatr Psychiatry
, vol.27
, pp. 592-600
-
-
De Jager, C.A.1
Oulhaj, A.2
Jacoby, R.3
Refsum, H.4
Smith, A.D.5
-
56
-
-
0037075257
-
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease
-
Seshadri S, Beiser A, Selhub J, Jacques PF, Rosenberg IH, D'Agostino RB, Wilson PW, Wolf PA (2002) Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med 346, 476-483.
-
(2002)
N Engl J Med
, vol.346
, pp. 476-483
-
-
Seshadri, S.1
Beiser, A.2
Selhub, J.3
Jacques, P.F.4
Rosenberg, I.H.5
D'Agostino, R.B.6
Wilson, P.W.7
Wolf, P.A.8
-
57
-
-
23044432096
-
Increase of total homocysteine concentration in cerebrospinal fluid in patients with Alzheimer's disease and Parkinson's disease
-
Isobe C, Murata T, Sato C, Terayama Y (2005) Increase of total homocysteine concentration in cerebrospinal fluid in patients with Alzheimer's disease and Parkinson's disease. Life Sci 77, 1836-1843.
-
(2005)
Life Sci
, vol.77
, pp. 1836-1843
-
-
Isobe, C.1
Murata, T.2
Sato, C.3
Terayama, Y.4
-
58
-
-
33947729229
-
Biomarkers of neurodegeneration for diagnosis and monitoring therapeutics
-
Shaw LM, Korecka M, Clark CM, Lee VM, Trojanowski JQ (2007) Biomarkers of neurodegeneration for diagnosis and monitoring therapeutics. Nat Rev Drug Discov 6, 295-303.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 295-303
-
-
Shaw, L.M.1
Korecka, M.2
Clark, C.M.3
Lee, V.M.4
Trojanowski, J.Q.5
-
59
-
-
78149313102
-
Sadenosylmethionine is decreased in the cerebrospinal fluid of patients with Alzheimer's disease
-
Linnebank M, Popp J, Smulders Y, Smith D, Semmler A, Farkas M, Kulic L, Cvetanovska G, Blom H, Stoffel-Wagner B, Kolsch H, Weller M, Jessen F (2010) Sadenosylmethionine is decreased in the cerebrospinal fluid of patients with Alzheimer's disease. Neurodegener Dis 7, 373-378.
-
(2010)
Neurodegener Dis
, vol.7
, pp. 373-378
-
-
Linnebank, M.1
Popp, J.2
Smulders, Y.3
Smith, D.4
Semmler, A.5
Farkas, M.6
Kulic, L.7
Cvetanovska, G.8
Blom, H.9
Stoffel-Wagner, B.10
Kolsch, H.11
Weller, M.12
Jessen, F.13
-
60
-
-
0029799427
-
Brain Sadenosylmethionine levels are severely decreased in Alzheimer's disease
-
Morrison LD, Smith DD, Kish SJ (1996) Brain Sadenosylmethionine levels are severely decreased in Alzheimer's disease. J Neurochem 67, 1328-1331.
-
(1996)
J Neurochem
, vol.67
, pp. 1328-1331
-
-
Morrison, L.D.1
Smith, D.D.2
Kish, S.J.3
-
61
-
-
0036250622
-
Biochemical markers related to Alzheimer's dementia in serum and cerebrospinal fluid
-
Teunissen CE, de Vente J, Steinbusch HW, De Bruijn C (2002) Biochemical markers related to Alzheimer's dementia in serum and cerebrospinal fluid. Neurobiol Aging 23, 485-508.
-
(2002)
Neurobiol Aging
, vol.23
, pp. 485-508
-
-
Teunissen, C.E.1
De Vente, J.2
Steinbusch, H.W.3
De Bruijn, C.4
-
62
-
-
65349162724
-
Hyperhomocysteinemia increases betaamyloid by enhancing expression of gamma-secretase and phosphorylation of amyloid precursor protein in rat brain
-
Zhang CE, Wei W, Liu YH, Peng JH, Tian Q, Liu GP, Zhang Y, Wang JZ (2009) Hyperhomocysteinemia increases betaamyloid by enhancing expression of gamma-secretase and phosphorylation of amyloid precursor protein in rat brain. Am J Pathol 174, 1481-1491.
-
(2009)
Am J Pathol
, vol.174
, pp. 1481-1491
-
-
Zhang, C.E.1
Wei, W.2
Liu, Y.H.3
Peng, J.H.4
Tian, Q.5
Liu, G.P.6
Zhang, Y.7
Wang, J.Z.8
-
63
-
-
76749128435
-
Acceleration of brain amyloidosis in an Alzheimer's disease mouse model by a folate, vitamin B6 and B12-deficient diet
-
Zhuo JM, Pratico D (2010) Acceleration of brain amyloidosis in an Alzheimer's disease mouse model by a folate, vitamin B6 and B12-deficient diet. Exp Gerontol 45, 195-201.
-
(2010)
Exp Gerontol
, vol.45
, pp. 195-201
-
-
Zhuo, J.M.1
Pratico, D.2
-
64
-
-
33745652285
-
Acontrolled trial of homocysteine lowering and cognitive performance
-
McMahon JA, Green TJ, Skeaff CM, Knight RG, Mann JI, WilliamsSM(2006)Acontrolled trial of homocysteine lowering and cognitive performance.NEngl J Med 354, 2764-2772.
-
(2006)
N Engl J Med
, vol.354
, pp. 2764-2772
-
-
McMahon, J.A.1
Green, T.J.2
Skeaff, C.M.3
Knight, R.G.4
Mann, J.I.5
Williams, S.M.6
-
65
-
-
33846037713
-
Vitamin B6 B12, and folic acid supplementation and cognitive function: A systematic review of randomized trials
-
Balk EM, Raman G, Tatsioni A, Chung M, Lau J, Rosenberg IH (2007) Vitamin B6, B12, and folic acid supplementation and cognitive function: A systematic review of randomized trials. Arch Intern Med 167, 21-30.
-
(2007)
Arch Intern Med
, vol.167
, pp. 21-30
-
-
Balk, E.M.1
Raman, G.2
Tatsioni, A.3
Chung, M.4
Lau, J.5
Rosenberg, I.H.6
-
66
-
-
48249091668
-
The worldwide challenge of the dementias: A role for B vitamins and homocysteine
-
Smith AD (2008) The worldwide challenge of the dementias: A role for B vitamins and homocysteine Food Nutr Bull 29, S143-S172.
-
(2008)
Food Nutr Bull
, vol.29
, pp. S143-S172
-
-
Smith, A.D.1
-
67
-
-
54049106963
-
High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: A randomized controlled trial
-
Aisen PS, Schneider LS, Sano M, Diaz-Arrastia R, van Dyck CH, Weiner MF, Bottiglieri T, Jin S, Stokes KT, Thomas RG, Thal LJ (2008) High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: A randomized controlled trial. JAMA 300, 1774-1783.
-
(2008)
JAMA
, vol.300
, pp. 1774-1783
-
-
Aisen, P.S.1
Schneider, L.S.2
Sano, M.3
Diaz-Arrastia, R.4
Van Dyck, C.H.5
Weiner, M.F.6
Bottiglieri, T.7
Jin, S.8
Stokes, K.T.9
Thomas, R.G.10
Thal, L.J.11
-
68
-
-
67650753876
-
The treatment of hyperhomocysteinemia
-
Maron BA, Loscalzo J (2009) The treatment of hyperhomocysteinemia. Annu Rev Med 60, 39-54.
-
(2009)
Annu Rev Med
, vol.60
, pp. 39-54
-
-
Maron, B.A.1
Loscalzo, J.2
-
69
-
-
33747418211
-
Homocysteine and cognition - A historical perspective
-
McCaddon A (2006) Homocysteine and cognition-a historical perspective. J Alzheimers Dis 9, 361-380.
-
(2006)
J Alzheimers Dis
, vol.9
, pp. 361-380
-
-
McCaddon, A.1
-
70
-
-
25444504855
-
Food-cobalamin malabsorption in elderly patients: Clinical manifestations and treatment
-
Andres E, Affenberger S, Vinzio S, Kurtz JE, Noel E, Kaltenbach G, Maloisel F, Schlienger JL, Blickle JF (2005) Food-cobalamin malabsorption in elderly patients: Clinical manifestations and treatment. Am J Med 118, 1154-1159.
-
(2005)
Am J Med
, vol.118
, pp. 1154-1159
-
-
Andres, E.1
Affenberger, S.2
Vinzio, S.3
Kurtz, J.E.4
Noel, E.5
Kaltenbach, G.6
Maloisel, F.7
Schlienger, J.L.8
Blickle, J.F.9
-
71
-
-
0031894738
-
Age-related changes in cobalamin (vitamin B12) handling Implications for therapy
-
Nilsson-Ehle H (1998) Age-related changes in cobalamin (vitamin B12) handling. Implications for therapy. Drugs Aging 12, 277-292.
-
(1998)
Drugs Aging
, vol.12
, pp. 277-292
-
-
Nilsson-Ehle, H.1
-
72
-
-
3142729264
-
Folate and vitamin B12 recommended intakes and status in the United States
-
discussion S21
-
Bailey LB (2004) Folate and vitamin B12 recommended intakes and status in the United States. Nutr Rev 62, S14-S20; discussion S21.
-
(2004)
Nutr Rev
, vol.62
, pp. S14-S20
-
-
Bailey, L.B.1
-
73
-
-
34248207745
-
IANA task force on nutrition and cognitive decline with aging
-
Gillette Guyonnet S, Abellan Van Kan G, Andrieu S, Barberger Gateau P, Berr C, BonnefoyM, Dartigues JF, de Groot L, Ferry M, Galan P, Hercberg S, Jeandel C, Morris MC, Nourhashemi F, Payette H, Poulain JP, Portet F, Roussel AM, Ritz P, Rolland Y, Vellas B (2007) IANA task force on nutrition and cognitive decline with aging. J Nutr Health Aging 11, 132-152.
-
(2007)
J Nutr Health Aging
, vol.11
, pp. 132-152
-
-
Gillette Guyonnet, S.1
Abellan Van Kan, G.2
Andrieu, S.3
Barberger Gateau, P.4
Berr, C.5
Bonnefoy, M.6
Dartigues, J.F.7
De Groot, L.8
Ferry, M.9
Galan, P.10
Hercberg, S.11
Jeandel, C.12
Morris, M.C.13
Nourhashemi, F.14
Payette, H.15
Poulain, J.P.16
Portet, F.17
Roussel, A.M.18
Ritz, P.19
Rolland, Y.20
Vellas, B.21
more..
-
74
-
-
33750360829
-
Synergy of genes and nutrients: The case of homocysteine
-
Lucock MD (2006) Synergy of genes and nutrients: The case of homocysteine. Curr Opin Clin Nutr Metab Care 9, 748-756.
-
(2006)
Curr Opin Clin Nutr Metab Care
, vol.9
, pp. 748-756
-
-
Lucock, M.D.1
|