A novel in vivo model of focal light emitting diode-induced cone-photoreceptor phototoxicity: Neuroprotection afforded by brimonidine, BDNF, PEDF or bFGF

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Ortín Martínez, Arturo ^a   Valiente Soriano, Francisco Javier ^a   García Ayuso, Diego ^a   Alarcón Martínez, Luis ^a   Jiménez López, Manuel ^a   Bernal Garro, José Manuel ^a   Nieto López, Leticia ^a   Nadal Nicolás, Francisco Manuel ^a   Villegas Péez, María Paz ^a   Wheeler, Larry A ^b   Vidal Sanz, Manuel ^a  

^a UNIVERSITY OF MURCIA   (Spain)

^b Zeteo Drug Discovery LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; BRAIN DERIVED NEUROTROPHIC FACTOR; BRIMONIDINE; CILIARY NEUROTROPHIC FACTOR; FIBROBLAST GROWTH FACTOR 2; OPSIN; PIGMENT EPITHELIUM DERIVED FACTOR; EYE PROTEIN; NERVE GROWTH FACTOR; NEUROPROTECTIVE AGENT; PIGMENT EPITHELIUM-DERIVED FACTOR; QUINOXALINE DERIVATIVE; SERINE PROTEINASE INHIBITOR;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; IMMUNOCYTOCHEMISTRY; IN VIVO STUDY; LIGHT EMITTING DIODE; NEUROPROTECTION; NONHUMAN; OPTICAL DENSITY; PHOTOTOXICITY; PROCESS OPTIMIZATION; RAT; RETINA CONE; RETINA DEGENERATION; RETINA INJURY; RETINAL THICKNESS; SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY; ADVERSE EFFECTS; ANIMAL; CELL SURVIVAL; DISEASE MODEL; DRUG EFFECTS; ELECTRONICS; LIGHT; OPTICAL COHERENCE TOMOGRAPHY; PATHOLOGY; RADIATION RESPONSE; SPRAGUE DAWLEY RAT; TIME;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; BRIMONIDINE TARTRATE; CELL SURVIVAL; DISEASE MODELS, ANIMAL; ELECTRONICS; EYE PROTEINS; FEMALE; FIBROBLAST GROWTH FACTOR 2; LIGHT; NERVE GROWTH FACTORS; NEUROPROTECTIVE AGENTS; QUINOXALINES; RATS, SPRAGUE-DAWLEY; RETINAL CONE PHOTORECEPTOR CELLS; SERPINS; TIME FACTORS; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84914680212     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113798     Document Type: Article

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