Automated quantification and topographical distribution of the whole population of S- and L-cones in adult albino and pigmented rats

Investigative Ophthalmology and Visual Science

Volumn 51, Issue 6, 2010, Pages 3171-3183

  Ortín Martínez, Arturo ^a,b,c   Jimenez Lopez, Manuel ^b,c   Nadal Nicolás, Francisco M ^a,b   Salinas Navarro, Manuel ^b   Alarcon Martínez, Luis ^b   Sauve, Yves ^c,d   Villegas Perez, Maria Paz ^b   Vidal San, Manuel ^b   Agudo Barriuso, Marta ^a  

^a Fundacion para la Formacion e Investigacion Sanitarias   (Spain)

^b UNIVERSITY OF MURCIA   (Spain)

^c UNIVERSITY OF ALBERTA   (Canada)

^d HOSPITAL UNIVERSITARIO VIRGEN DE LA ARRIXACA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR POU4F1; LONG WAVELENGTH OPSIN; LONG-WAVELENGTH OPSIN; SCOTOPSIN; SHORT WAVELENGTH OPSIN; SHORT-WAVELENGTH OPSIN;

ALBINISM; ANIMAL TISSUE; ARTICLE; AUTOMATION; CELL COUNT; CELL DENSITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; L CONE; NONHUMAN; PIEBALD VIROL GLAXO RAT; PIGMENTATION; PRIORITY JOURNAL; RAT; RETINA CONE; RETINA GANGLION CELL; S CONE; SPRAGUE DAWLEY RAT; ANIMAL; CYTOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM;

ANIMALS; CELL COUNT; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; RATS; RATS, SPRAGUE-DAWLEY; RETINAL CONE PHOTORECEPTOR CELLS; ROD OPSINS; TRANSCRIPTION FACTOR BRN-3A;

EID: 77952878859     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4861     Document Type: Article

References (50)

1. Szel A, Rohlich P, van Veen T. Short-wave sensitive cones in the rodent retinas. Exp Eye Res. 1993;57:503-505.
2. Bowmaker JK, Hunt DM. Evolution of vertebrate visual pigments. CurrBiol. 2006;16:R484-R489.
3. Jacobs GH, Fenwick JA, Williams GA. Cone-based vision of rats for ultraviolet and visible lights. J Exp Biol. 2001;204:2439-2446.
4. Applebury ML, Antoch MP, Baxter LC, et al. The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning. Neuron. 2000;27:513-523.
5. Lukats A, Szabo A, Rohlich P, Vigh B, Szel A. Photopigment coex-pression in mammals: comparative and developmental aspects. Histol Histopathol. 2005;20:551-574.
6. Rohlich P, van Veen T, Szel A. Two different visual pigments in one retinal cone cell. Neuron. 1994;13:1159-1166.
7. Aviles-Trigueros M, Sauve Y, Lund RD, Vidal-Sanz M. Selective innervation of retinorecipient brainstem nuclei by retinal ganglion cell axons regenerating through peripheral nerve grafts in adult rats. J Neurosci. 2000;20:361-374.
8. Whiteley SJ, Sauve Y, Aviles-Trigueros M, Vidal-Sanz M, Lund RD. Extent and duration of recovered pupillary light reflex following retinal ganglion cell axon regeneration through peripheral nerve grafts directed to the pretectum in adult rats. Exp Neurol. 1998; 154:560-572.
9. Vidal-Sanz M, de la Villa P, Aviles-Trigueros M, et al. Neuroprotec-tion of retinal ganglion cell function and their central nervous system targets. Eye. 2007;21:S42-S45.
10. Aguayo AJ, Vidal-Sanz M, Villegas-Perez MP, Bray GM. Growth and connectivity of axotomized retinal neurons in adult rats with optic nerves substituted by PNS grafts linking the eye and the midbrain. Ann NY Acad Sci. 1987;495:1-9.
11. Sasaki H, Coffey P, Villegas-Perez MP, et al. Light induced EEG desynchronization and behavioral arousal in rats with restored retinocollicular projection by peripheral nerve graft. Neurosci Lett. 1996;218:45-48.
12. Vidal-Sanz M, Lafuente MP, Mayor S, de Imperial JM, Villegas-Perez MP. Retinal ganglion cell death induced by retinal ischemia: neu-roprotective effects of two alpha-2 agonists. Surv Ophthalmol. 2001;45(suppl 3):S261-S267.
13. Marco-Gomariz MA, Hurtado-Montalban N, Vidal-Sanz M, Lund RD, Villegas-Perez MP. Phototoxic-induced photoreceptor degeneration causes retinal ganglion cell degeneration in pigmented rats. J Comp Neurol. 2006;498:163-179.
14. Sancho-Pelluz J, Arango-Gonzalez B, Kustermann S, et al. Photore-ceptor cell death mechanisms in inherited retinal degeneration. Mol Neurobiol. 2008;38:253-269.
15. Villegas-Perez MP, Vidal-Sanz M, Lund RD. Mechanism of retinal ganglion cell loss in inherited retinal dystrophy. Neuroreport. 1996;7:1995-1999.
16. Vugler A, Semo M, Joseph A, Jeffery G. Survival and remodeling of melanopsin cells during retinal dystrophy. Vis Neurosci. 2008;25: 125-138.
17. Ahnelt PK, Schubert C, Kubber-Heiss A, Schiviz A, Anger E. Independent variation of retinal S and M cone photoreceptor topographies: a survey of four families of mammals. Vis Neurosci. 2006;23:429-435.
18. Peichl L. Diversity of mammalian photoreceptor properties: adaptations to habitat and lifestyle? Anat Rec A Discov Mol Cell Evol Biol. 2005;287:1001-1012.
19. Hendrickson A, Hicks D. Distribution and density of medium- and short-wavelength selective cones in the domestic pig retina. Exp Eye Res. 2002;74:435-444.
20. Hendrickson A, Djajadi HR, Nakamura L, Possin DE, Sajuthi D. Nocturnal tarsier retina has both short and long/medium-wavelength cones in an unusual topography. J Comp Neurol. 2000;424: 718-730.
21. Jacobs GH. Primate color vision: a comparative perspective. Vis Neurosci. 2008;25:619-633.
22. Szel A, Lukats A, Fekete T, Szepessy Z, Rohlich P. Photoreceptor distribution in the retinas of subprimate mammals. J Opt Soc Am A Opt Image Sci Vis. 2000;17:568-579.
23. Williams RW. The human retina has a cone-enriched rim. Vis Neurosci. 1991;6:403-406.
24. Bobu C, Lahmam M, Vuillez P, Ouarour A, Hicks D. Photoreceptor organisation and phenotypic characterization in retinas of two diurnal rodent species: potential use as experimental animal models for human vision research. Vision Res. 2008;48:424-432.
25. Gaillard F, Bonfield S, Gilmour GS, et al. Retinal anatomy and visual performance in a diurnal cone-rich laboratory rodent, the Nile grass rat (Arvicanthis niloticus). J Comp Neurol. 2008;510:525-538.
26. Gaillard F, Kuny S, Sauve Y. Topographic arrangement of S-cone photoreceptors in the retina of the diurnal Nile grass rat (Arvican-this niloticus). Invest Ophthalmol Vis Sci. 2009;50:5426-5434.
27. Glosmann M, Steiner M, Peichl L, Ahnelt PK. Cone photoreceptors and potential UV vision in a subterranean insectivore, the European mole. J Vis. 2008:8:1-12.
28. Lukats A, Dkhissi-Benyahya O, Szepessy Z, et al. Visual pigment coexpression in all cones of two rodents, the Siberian hamster, and the pouched mouse. Invest Ophthalmol Vis Sci. 2002;43:2468-2473.
29. Neitz M, Neitz J. The uncommon retina of the common house mouse. Trends Neurosci. 2001;24:248-250.
30. Peichl L, Nemec P, Burda H. Unusual cone and rod properties in subterranean African mole-rats (Rodentia, Bathyergidae). Eur J Neurosci. 2004;19:1545-1558.
31. Szel A, Csorba G, Caffe AR, Szel G, Rohlich P, van Veen T. Different patterns of retinal cone topography in two genera of rodents, Mus and Apodemus. Cell Tissue Res. 1994;276:143-150.
32. Chrysostomou V, Stone J, Valter K. Life history of cones in the rhodopsin-mutant P23H-3 rat: evidence of long-term survival. Invest Ophthalmol Vis Sci. 2009;50:2407-2416.
33. Heiduschka P, Schraermeyer U. Comparison of visual function in pigmented and albino rats by electroretinography and visual evoked potentials. Graefes Arch Clin Exp Ophthalmol. 2008;246: 1559-1573.
34. Szel A, Rohlich P. Two cone types of rat retina detected by anti-visual pigment antibodies. Exp Eye Res. 1992;55:47-52.
35. Szel A, van Veen T, Rohlich P. Retinal cone differentiation. Nature. 1994;370:336.
36. Nadal-Nicolas FM, Jimenez-Lopez M, Sobrado-Calvo P, et al. Brn3a as a marker of retinal ganglion cells: qualitative and quantitative time course studies in naive and optic nerve-injured retinas. Invest Ophthalmol Vis Sci. 2009;50:3860-3868.
37. Salinas-Navarro M, Mayor-Torroglosa S, Jimenez-Lopez M, et al. A computerized analysis of the entire retinal ganglion cell population and its spatial distribution in adult rats. Vision Res. 2009;49:115-126.
38. Salinas-Navarro M, Alarcon-Martinez L, Valiente-Soriano FJ, et al. Ocular hypertension impairs optic nerve axonal transport leading to progressive retinal ganglion cell degeneration. Exp Eye Res. 2010;90(1):168-183.
39. Salinas-Navarro M, Alarcon-Martinez L, Valiente-Soriano FJ, et al. Functional and morphological effects of laser-induced ocular hypertension in retinas of adult albino Swiss mice. Mol Vis. 2009;15: 2578-2598.
40. Parrilla-Reverter G, Agudo M, Nadal-Nicolas F, et al. Time-course of the retinal nerve fibre layer degeneration after complete intra-orbital optic nerve transection or crush: a comparative study. Vision Res. 2009;49(23):2808-2825.
41. Semo M, Vugler AA, Jeffery G. Paradoxical opsin expressing cells in the inner retina that are augmented following retinal degeneration. Eur J Neurosci. 2007;25:2296-2306.
42. Salinas-Navarro M, Jimenez-Lopez M, Valiente-Soriano FJ, et al. Retinal ganglion cell population in adult albino and pigmented mice: a computerized analysis of the entire population and its spatial distribution. Vision Res. 2009;49:637-647.
43. Wenzel A, Grimm C, Samardzija M, Reme CE. Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotec-tion for retinal degeneration. Prog Retin Eye Res. 2005;24:275-306.
44. Pennesi ME, Nishikawa S, Matthes MT, Yasumura D, LaVail MM. The relationship of photoreceptor degeneration to retinal vascular development and loss in mutant rhodopsin transgenic and RCS rats. Exp Eye Res. 2008;87:561-570.
45. Juliusson B, Bergstrom A, Rohlich P, Ehinger B, van Veen T, Szel A. Complementary cone fields of the rabbit retina. Invest Ophthal-mol Vis Sci. 1994;35:811-818.
46. Mollon JD, Regan BC, Bowmaker JK. What is the function of the cone-rich rim of the retina? Eye 1998;12:548-552.
47. Dacey DM, Liao HW, Peterson BB, et al. Melanopsin-expressing ganglion cells in primate retina signal colour and irradiance and project to the LGN. Nature. 2005;433:749-754.
48. Rodieck RW. The First Steps in Seeing. Sunderland, MA: Sinauer Associates, Inc.; 1998.
49. Schulte D, Bumsted-O'Brien KM. Molecular mechanisms of vertebrate retina development: implications for ganglion cell and pho-toreceptor patterning. Brain Res. 2008;1192:151-164.
50. Jacobs GH, Williams GA, Fenwick JA. Influence of cone pigment coexpression on spectral sensitivity and color vision in the mouse. Vision Res. 2004;44:1615-1622.