The Effect of Retinal Ganglion Cell Injury on Light-Induced Photoreceptor Degeneration

Investigative Ophthalmology and Visual Science

Volumn 45, Issue 2, 2004, Pages 685-693

  Casson, Robert ^a   Chidlow, Glyn ^a   Wood, John P M ^a   Vidal Sanz, Manuel ^b   Osborne, Neville N ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF MURCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CILIARY NEUROTROPHIC FACTOR; FIBROBLAST GROWTH FACTOR 2; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID; NERVE GROWTH FACTOR; RHODOPSIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL DEGENERATION; CYTOTOXICITY; ELECTRORETINOGRAPHY; FEMALE; HISTOPATHOLOGY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LIGHT DAMAGE; MALE; NERVE TRANSECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPTIC NERVE; PHOTORECEPTOR CELL; PHOTOSTIMULATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL;

ANIMALS; AXOTOMY; CILIARY NEUROTROPHIC FACTOR; ELECTRORETINOGRAPHY; EYE PROTEINS; FEMALE; FIBROBLAST GROWTH FACTOR 2; GLIAL FIBRILLARY ACIDIC PROTEIN; LIGHT; N-METHYLASPARTATE; OPSIN; OPTIC NERVE; PHOTORECEPTORS, VERTEBRATE; PROTEIN KINASES; RADIATION INJURIES, EXPERIMENTAL; RATS; RATS, WISTAR; RETINAL DEGENERATION; RETINAL GANGLION CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHODOPSIN KINASE; RNA, MESSENGER; UP-REGULATION;

EID: 0942265567     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.03-0674     Document Type: Article

References (36)

1. Faktorovich EG, Steinberg RH, Yasumura D, Matthes MT, LaVail MM. Basic fibroblast growth factor and local injury protect photoreceptors from light damage in the rat. J Neurosci. 1992;12:3554-3567.
2. Liu C, Peng M, Laties AM, Wen R. Preconditioning with bright light evokes a protective response against light damage in the rat retina. J Neurosci. 1998;18:1337-1344.
3. Casson R, Wood J, Melena J, Chidlow G, Osborne N. The effect of ischemic preconditioning on light-induced photoreceptor injury. Invest Ophthalmol Vis Sci. 2003;44:1355-1363.
4. Bush RA, Williams TP. The effect of unilateral optic nerve section on retinal light damage in rats. Exp Eye Res. 1991;52:139-153.
5. Kostyk SK, D'Amore PA, Herman IM, Wagner JA. Optic nerve injury alters basic fibroblast growth factor localization in the retina and optic tract. J Neurosci. 1994;14:1441-1449.
6. Wahlin KJ, Campochiaro PA, Zack DJ, Adler R. Neurotrophic factors cause activation of intracellular signaling pathways in Müller cells and other cells of the inner retina, but not photoreceptors. Invest Ophthalmol Vis Sci. 2000;41:927-936.
7. Chong NH, Alexander RA, Waters L, Barnett KC, Bird AC, Luthert PJ. Repeated injections of a ciliary neurotrophic factor analogue leading to long-term photoreceptor survival in hereditary retinal degeneration. Invest Ophthalmol Vis Sci. 1999;40:1298-1305.
8. Frasson M, Picaud S, Leveillard T, et al. Glial cell line-derived neurotrophic factor induces histologic and functional protection of rod photoreceptors in the rd/rd mouse. Invest Ophthalmol Vis Sci. 1999;40:2724-2734.
9. Cayouette M, Behn D, Sendtner M, Lachapelle P, Gravel C. Intraocular gene transfer of ciliary neurotrophic factor prevents death and increases responsiveness of rod photoreceptors in the retinal degeneration slow mouse. J Neurosci. 1998;18:9282-9293.
10. LaVail MM, Unoki K, Yasumura D, Matthes MT, Yancopoulos GD, Steinberg RH. Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light. Proc Natl Acad Sci USA. 1992;89:11249-11253.
11. Nash MS, Osborne NN. Assessment of Thy-1 mRNA levels as an index of retinal ganglion cell damage. Invest Ophthalmol Vis Sci. 1999;40:1293-1298.
12. Berardi N, Domenici L, Gravina A, Maffei L. Pattern ERG in rats following section of the optic nerve. Exp Brain Res. 1990;79:539-546.
13. Mafei L, Fiorentini A. Electroretinographic responses to alternating gratings before and after section of the optic nerve. Science. 1981;211:953-955.
14. Dawson WW, Maida TM, Rubin ML. Human pattern-evoked retinal responses are altered by optic atrophy. Invest Ophthalmol Vis Sci. 1982;22:796-803.
15. Harrison JM, O'Connor PS, Young RS, Kincaid M, Bentley R. The pattern ERG in man following surgical resection of the optic nerve. Invest Ophthalmol Vis Sci. 1987;28:492-499.
16. Gargini C, Belfiore MS, Bisti S, Cervetto L, Valter K, Stone J. The impact of basic fibroblast growth factor on photoreceptor function and morphology. Invest Ophthalmol Vis Sci. 1999;40:2088-2099.
17. Vaegan, Anderton PJ, Millar TJ. Multifocal, pattern and full field electroretinogrmas in cats with unilateral optic nerve section. Doc Ophthalmol. 2000;100:207-229.
18. Vaegan, Graham SL, Goldberg I, Buckland L, Hollows FC. Flash and pattern electroretinogram changes with optic atrophy and glaucoma. Exp Eye Res. 1995;60:697-706.
19. Velten IM, Korth M, Horn FK. The a-wave of the dark adapted electroretinogram in glaucomas: are photoreceptors affected? Br J Ophthalmol. 2001;85:397-402.
20. Velten IM, Horn FK, Korth M, Velten K. The b-wave of the dark adapted flash electroretinogram in patients with advanced asymmetrical glaucoma and normal subjects. Br J Ophthalmol. 2001;85:403-409.
21. Sugiyama K, Gu ZB, Kawase C, Yamamoto T, Kitazawa Y. Optic nerve and peripapillary choroidal microvasculature of the rat eye. Invest Ophthalmol Vis Sci. 1999;40:3084-3090.
22. Domenici L, Gravina A, Berardi N, Maffei L. Different effects of intracranial and intraorbital section of the optic nerve on the functional responses of rat retinal ganglion cells. Exp Brain Res. 1991;86:579-584.
23. Osborne NN, Larsen A, Barnett NL. Influence of excitatory amino acids and ischemia on rat retinal choline acetyltransferase-containing cells. Invest Ophthalmol Vis Sci. 1995;36:1692-1700.
24. Osborne N, Perry V. Effect of neonatal optic nerve transection on some classes of amacrine cells in the rat retina. Brain Res. 1985;23:230-235.
25. Wen R, Song Y, Cheng T, et al. Injury-induced upregulation of bFGF and CNTF mRNAs in the rat retina. J Neurosci. 1995;15:7377-7385.
26. LaVail MM, Yasumura D, Matthes MT, et al. Protection of mouse photoreceptors by survival factors in retinal degenerations. Invest Ophthalmol Vis Sci. 1998;39:592-602.
27. Stone J, Maslim J, Valter Kocsi K, et al. Mechanisms of photoreceptor death and survival in mammalian retina. Prog Retin Eye Res. 1999;18:689-735.
28. Chun MH, Ju WK, Kim KY, et al. Upregulation of ciliary neurotrophic factor in reactive Muller cells in the rat retina following optic nerve transection. Brain Res. 2000;868:358-362.
29. Kirsch M, Lee MY, Meyer V, Wiese A, Hofmann HD. Evidence for multiple, local functions of ciliary neurotrophic factor (CNTF) in retinal development: expression of CNTF and its receptors and in vitro effects on target cells. J Neurochem. 1997;68:979-990.
30. Ugolini G, Cremisi F, Maffei L. TrkA, TrkB and p75 mRNA expression is developmentally regulated in the rat retina. Brain Res. 1995;704:121-124.
31. Zack DJ. Neurotrophic rescue of photoreceptors: are Muller cells the mediators of survival? Neuron. 2000;26:285-286.
32. Bringmann A, Reichenbach A. Role of Muller cells in retinal degenerations. Front Biosci. 2001;6:E72-E92.
33. Harada T, Harada C, Nakayama N, et al. Modification of glial-neuronal cell interactions prevents photoreceptor apoptosis during light-induced retinal degeneration. Neuron. 2000;26:533-541.
34. Harada T, Harada C, Kohsaka S, et al. Microglia-Muller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration. J Neurosci. 2002;22:9228-9236.
35. Siliprandi R, Canella R, Carmignoto G, et al. N-methyl-D-aspartate-induced neurotoxicity in the adult rat retina. Vis Neurosci. 1992;8:567-573.
36. Vecino E, Ugarte M, Nash MS, Osborne NN. NMDA induces BDNF expression in the albino rat retina in vivo. Neuroreport. 1999;10:1103-1106.