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Volumn 90, Issue 1, 2010, Pages 168-183

Ocular hypertension impairs optic nerve axonal transport leading to progressive retinal ganglion cell degeneration

Author keywords

adult albino rat retinal ganglion cells; Brn3a; dextran tetramethylrhodamine; fluorescent tracers; fluorogold; neuronal degeneration; ocular hypertension; phosphorilated neurofilament heavy chain; retrograde axonal transport; RT97

Indexed keywords

FLUOROGOLD; TETRAMETHYLRHODAMINE; TRANSCRIPTION FACTOR POU4F1;

EID: 70749091291     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2009.10.003     Document Type: Article
Times cited : (131)

References (79)
  • 3
    • 70749092408 scopus 로고    scopus 로고
    • Alarcón-Martínez, L., De la Villa, P., Avilés-Trigueros, M., BlancoR., Villegas-Perez, M.P., Vidal-Sanz, M. Short and long term axotomy-induced ERG changes in albino and pigmented rats. Mol. Vis, in press.
    • Alarcón-Martínez, L., De la Villa, P., Avilés-Trigueros, M., BlancoR., Villegas-Perez, M.P., Vidal-Sanz, M. Short and long term axotomy-induced ERG changes in albino and pigmented rats. Mol. Vis, in press.
  • 6
    • 0022355015 scopus 로고
    • Light-dependent antibody labelling of photoreceptors
    • Balkema G.W., and Drager U.C. Light-dependent antibody labelling of photoreceptors. Nature 316 (1985) 630-633
    • (1985) Nature , vol.316 , pp. 630-633
    • Balkema, G.W.1    Drager, U.C.2
  • 8
    • 25444496516 scopus 로고    scopus 로고
    • Measurement of retinal injury in the rat after optic nerve transection: an RT-PCR study
    • Chidlow G., Casson R., Sobrado-Calvo P., Vidal-Sanz M., and Osborne N.N. Measurement of retinal injury in the rat after optic nerve transection: an RT-PCR study. Mol. Vis. 11 (2005) 387-396
    • (2005) Mol. Vis. , vol.11 , pp. 387-396
    • Chidlow, G.1    Casson, R.2    Sobrado-Calvo, P.3    Vidal-Sanz, M.4    Osborne, N.N.5
  • 11
    • 0021279270 scopus 로고
    • Antibodies to heavy neurofilament subunit detect a subpopulation of damaged ganglion cells in retina
    • Drager U.C., and Hofbauer A. Antibodies to heavy neurofilament subunit detect a subpopulation of damaged ganglion cells in retina. Nature 309 (1984) 624-626
    • (1984) Nature , vol.309 , pp. 624-626
    • Drager, U.C.1    Hofbauer, A.2
  • 14
    • 0029970813 scopus 로고    scopus 로고
    • Retinotopy of the human retinal nerve fibre layer and optic nerve head
    • Fitzgibbon T., and Taylor S.F. Retinotopy of the human retinal nerve fibre layer and optic nerve head. J. Comp. Neurol. 375 (1996) 238-251
    • (1996) J. Comp. Neurol. , vol.375 , pp. 238-251
    • Fitzgibbon, T.1    Taylor, S.F.2
  • 16
    • 0029011488 scopus 로고
    • Developmental determinants at the mammalian optic chiasm
    • Guillery R.W., Mason C.A., and Taylor J.S.H. Developmental determinants at the mammalian optic chiasm. J. Neurosci. 15 (1995) 4727-4737
    • (1995) J. Neurosci. , vol.15 , pp. 4727-4737
    • Guillery, R.W.1    Mason, C.A.2    Taylor, J.S.H.3
  • 18
    • 27544480984 scopus 로고    scopus 로고
    • Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice
    • Jakobs T.C., Libby R.T., Ben Y., John S.W., and Masland R.H. Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice. J. Cell. Biol. 171 (2005) 313-325
    • (2005) J. Cell. Biol. , vol.171 , pp. 313-325
    • Jakobs, T.C.1    Libby, R.T.2    Ben, Y.3    John, S.W.4    Masland, R.H.5
  • 19
    • 0034789698 scopus 로고    scopus 로고
    • Architecture of the optic chiasm and the mechanisms that sculpt its development
    • Jeffery G. Architecture of the optic chiasm and the mechanisms that sculpt its development. Physiol. Rev. 81 (2001) 1393-14114
    • (2001) Physiol. Rev. , vol.81 , pp. 1393-14114
    • Jeffery, G.1
  • 20
    • 56249094841 scopus 로고    scopus 로고
    • Segregated hemispheric pathways through the optic chiasm distinguish primates from rodents
    • Jeffery G., Levitt J.B., and Cooper H.M. Segregated hemispheric pathways through the optic chiasm distinguish primates from rodents. Neuroscience 157 (2008) 637-643
    • (2008) Neuroscience , vol.157 , pp. 637-643
    • Jeffery, G.1    Levitt, J.B.2    Cooper, H.M.3
  • 21
    • 0034055591 scopus 로고    scopus 로고
    • Patterns of intraocular pressure elevation after aqueous humor outflow obstruction in rats
    • Jia L., Cepurna W.O., Johnson E.C., and Morrison J.C. Patterns of intraocular pressure elevation after aqueous humor outflow obstruction in rats. Invest. Ophthalmol. Vis. Sci. 41 (2000) 1380-1385
    • (2000) Invest. Ophthalmol. Vis. Sci. , vol.41 , pp. 1380-1385
    • Jia, L.1    Cepurna, W.O.2    Johnson, E.C.3    Morrison, J.C.4
  • 25
    • 0036353967 scopus 로고    scopus 로고
    • Neuroprotective effects of brimonidine against transient ischemia-induced retinal ganglion cell death: a dose response in vivo study
    • Lafuente M.P., Villegas-Pérez M.P., Mayor S., Aguilera M.E., Miralles de Imperial J., and Vidal-Sanz M. Neuroprotective effects of brimonidine against transient ischemia-induced retinal ganglion cell death: a dose response in vivo study. Exp. Eye Res. 74 (2002) 181-189
    • (2002) Exp. Eye Res. , vol.74 , pp. 181-189
    • Lafuente, M.P.1    Villegas-Pérez, M.P.2    Mayor, S.3    Aguilera, M.E.4    Miralles de Imperial, J.5    Vidal-Sanz, M.6
  • 32
    • 0025266780 scopus 로고
    • Slow transport rates of cytoskeletal proteins change during regeneration of axotomized retinal neurons in adult rats
    • McKerracher L., Vidal-Sanz M., and Aguayo A.J. Slow transport rates of cytoskeletal proteins change during regeneration of axotomized retinal neurons in adult rats. J. Neurosci. 10 (1990) 641-648
    • (1990) J. Neurosci. , vol.10 , pp. 641-648
    • McKerracher, L.1    Vidal-Sanz, M.2    Aguayo, A.J.3
  • 33
    • 0025471214 scopus 로고
    • Selective impairment of slow axonal transport after optic nerve injury in adult rats
    • McKerracher L., Vidal-Sanz M., Essagian C., and Aguayo A.J. Selective impairment of slow axonal transport after optic nerve injury in adult rats. J. Neurosci. 10 (1990) 2834-2841
    • (1990) J. Neurosci. , vol.10 , pp. 2834-2841
    • McKerracher, L.1    Vidal-Sanz, M.2    Essagian, C.3    Aguayo, A.J.4
  • 34
    • 0029913221 scopus 로고    scopus 로고
    • Circadian rhythm of intraocular pressure in the rat
    • Moore C.G., Johnson E.C., and Morrison J.C. Circadian rhythm of intraocular pressure in the rat. Curr. Eye Res. 15 (1996) 185-191
    • (1996) Curr. Eye Res. , vol.15 , pp. 185-191
    • Moore, C.G.1    Johnson, E.C.2    Morrison, J.C.3
  • 35
    • 0027457904 scopus 로고
    • Noninvasive measurement of rat intraocular pressure with the tono-pen
    • Moore C.G., Milne S.T., and Morrison J.C. Noninvasive measurement of rat intraocular pressure with the tono-pen. Invest. Ophthalmol. Vis. Sci. 34 (1993) 363-369
    • (1993) Invest. Ophthalmol. Vis. Sci. , vol.34 , pp. 363-369
    • Moore, C.G.1    Milne, S.T.2    Morrison, J.C.3
  • 37
    • 11144334117 scopus 로고    scopus 로고
    • Understanding mechanisms of pressure-induced optic nerve damage
    • Morrison J.C., Johnson E.C., Cepurna W., and Jia L. Understanding mechanisms of pressure-induced optic nerve damage. Prog. Retin. Eye Res. 24 (2005) 217-240
    • (2005) Prog. Retin. Eye Res. , vol.24 , pp. 217-240
    • Morrison, J.C.1    Johnson, E.C.2    Cepurna, W.3    Jia, L.4
  • 40
    • 0032932399 scopus 로고    scopus 로고
    • Assessment of Thy-1 mRNA levels as an index of retinal ganglion cell damage
    • Nash M.S., and Osborne N.N. Assessment of Thy-1 mRNA levels as an index of retinal ganglion cell damage. Invest. Ophthalmol. Vis. Sci. 40 (1999) 1293-1298
    • (1999) Invest. Ophthalmol. Vis. Sci. , vol.40 , pp. 1293-1298
    • Nash, M.S.1    Osborne, N.N.2
  • 41
    • 4444335507 scopus 로고    scopus 로고
    • Predictive factors for glaucomatous visual field progression in the advanced glaucoma intervention study
    • Nouri-Mahdavi K., Hoffman D., Coleman A.L., Liu G., Li G., Gaasterland D., and Caprioli J. Predictive factors for glaucomatous visual field progression in the advanced glaucoma intervention study. Ophthalmology 111 (2004) 1627-1635
    • (2004) Ophthalmology , vol.111 , pp. 1627-1635
    • Nouri-Mahdavi, K.1    Hoffman, D.2    Coleman, A.L.3    Liu, G.4    Li, G.5    Gaasterland, D.6    Caprioli, J.7
  • 43
    • 67349217127 scopus 로고    scopus 로고
    • Effects of different neurotrophic factors on the survival of retinal ganglion cells after a complete intraorbital nerve crush injury: a quantitative in vivo study
    • 10.1016/j.exer.2009.02.015
    • Parrilla-Reverter G., Agudo M., Sobrado-Calvo P., Salinas-Navarro M., Villegas-Pérez M.P., and Vidal-Sanz M. Effects of different neurotrophic factors on the survival of retinal ganglion cells after a complete intraorbital nerve crush injury: a quantitative in vivo study. Exp. Eye Res. 89 (2009) 32-41 10.1016/j.exer.2009.02.015
    • (2009) Exp. Eye Res. , vol.89 , pp. 32-41
    • Parrilla-Reverter, G.1    Agudo, M.2    Sobrado-Calvo, P.3    Salinas-Navarro, M.4    Villegas-Pérez, M.P.5    Vidal-Sanz, M.6
  • 46
    • 0029979673 scopus 로고    scopus 로고
    • Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. a quantitative in vivo study
    • Peinado-Ramón P., Salvador M., Villegas-Pérez M.P., and Vidal-Sanz M. Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. a quantitative in vivo study. Invest. Ophthalmol. Vis. Sci. 37 (1996) 489-500
    • (1996) Invest. Ophthalmol. Vis. Sci. , vol.37 , pp. 489-500
    • Peinado-Ramón, P.1    Salvador, M.2    Villegas-Pérez, M.P.3    Vidal-Sanz, M.4
  • 47
    • 0017123773 scopus 로고
    • The dynamics and location of axonal transport blockade by acute intraocular pressure elevation in primate optic nerve
    • Quigley H., and Anderson D.R. The dynamics and location of axonal transport blockade by acute intraocular pressure elevation in primate optic nerve. Invest. Ophthalmol. 15 (1976) 606-616
    • (1976) Invest. Ophthalmol. , vol.15 , pp. 606-616
    • Quigley, H.1    Anderson, D.R.2
  • 48
    • 0017687084 scopus 로고
    • Distribution of axonal transport blockade by acute intraocular pressure elevation in the primate optic nerve head
    • Quigley H.D., and Anderson D.R. Distribution of axonal transport blockade by acute intraocular pressure elevation in the primate optic nerve head. Invest. Ophthalmol. Vis. Sci. 16 (1977) 640-644
    • (1977) Invest. Ophthalmol. Vis. Sci. , vol.16 , pp. 640-644
    • Quigley, H.D.1    Anderson, D.R.2
  • 49
    • 0018877393 scopus 로고
    • Chronic experimental glaucoma in primates. II. Effect of extended intraocular pressure elevation on optic nerve head and axonal transport
    • Quigley H.A., and Addicks E.M. Chronic experimental glaucoma in primates. II. Effect of extended intraocular pressure elevation on optic nerve head and axonal transport. Invest. Ophthalmol. Vis. Sci. 19 (1980) 137-152
    • (1980) Invest. Ophthalmol. Vis. Sci. , vol.19 , pp. 137-152
    • Quigley, H.A.1    Addicks, E.M.2
  • 50
    • 0019523221 scopus 로고
    • Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage
    • Quigley H.A., Addicks E.M., Green W.R., and Maumenee A.E. Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage. Arch. Ophthalmol. 99 (1981) 635-649
    • (1981) Arch. Ophthalmol. , vol.99 , pp. 635-649
    • Quigley, H.A.1    Addicks, E.M.2    Green, W.R.3    Maumenee, A.E.4
  • 51
    • 0020619743 scopus 로고
    • Laser energy levels for trabecular meshwork damage in the primate eye
    • Quigley H.A., and Hohman R.M. Laser energy levels for trabecular meshwork damage in the primate eye. Invest. Ophthalmol. Vis. Sci. 24 (1983) 1305-1307
    • (1983) Invest. Ophthalmol. Vis. Sci. , vol.24 , pp. 1305-1307
    • Quigley, H.A.1    Hohman, R.M.2
  • 57
    • 0034695998 scopus 로고    scopus 로고
    • Microglial cells in the retina of Carassius auratus: effects of optic nerve crush
    • Salvador-Silva M., Vidal-Sanz M., and Villegas-Pérez M.P. Microglial cells in the retina of Carassius auratus: effects of optic nerve crush. J. Comp. Neurol. 417 (2000) 431-447
    • (2000) J. Comp. Neurol. , vol.417 , pp. 431-447
    • Salvador-Silva, M.1    Vidal-Sanz, M.2    Villegas-Pérez, M.P.3
  • 58
    • 0029785595 scopus 로고    scopus 로고
    • Retinal ganglion cell death after different transient periods of pressure-induced ischemia and survival intervals: a quantitative in vivo study
    • Sellés-Navarro I., Villegas-Pérez M.P., Salvador-Silva M., Ruiz-Gómez M., and Vidal-Sanz M. Retinal ganglion cell death after different transient periods of pressure-induced ischemia and survival intervals: a quantitative in vivo study. Invest. Opthalmol. Vis. Sci. 37 (1996) 2002-2014
    • (1996) Invest. Opthalmol. Vis. Sci. , vol.37 , pp. 2002-2014
    • Sellés-Navarro, I.1    Villegas-Pérez, M.P.2    Salvador-Silva, M.3    Ruiz-Gómez, M.4    Vidal-Sanz, M.5
  • 59
    • 34247603570 scopus 로고    scopus 로고
    • Rat retinal microglial cells under normal conditions, after optic nerve section, and after optic nerve section and intravitreal injection of trophic factors or macrophage inhibitory factor
    • Sobrado-Calvo P., Vidal-Sanz M., and Villegas-Pérez M.P. Rat retinal microglial cells under normal conditions, after optic nerve section, and after optic nerve section and intravitreal injection of trophic factors or macrophage inhibitory factor. J. Comp. Neurol. 501 (2007) 866-878
    • (2007) J. Comp. Neurol. , vol.501 , pp. 866-878
    • Sobrado-Calvo, P.1    Vidal-Sanz, M.2    Villegas-Pérez, M.P.3
  • 60
    • 0347895122 scopus 로고    scopus 로고
    • Changes in Thy1 gene expression associated with damaged retinal ganglion cells
    • Schlamp C.L., Johnson E.C., Li Y., Morrison J.C., and Nickells R.W. Changes in Thy1 gene expression associated with damaged retinal ganglion cells. Mol. Vis. 7 (2001) 192-201
    • (2001) Mol. Vis. , vol.7 , pp. 192-201
    • Schlamp, C.L.1    Johnson, E.C.2    Li, Y.3    Morrison, J.C.4    Nickells, R.W.5
  • 61
    • 33750381831 scopus 로고    scopus 로고
    • Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric
    • Schlamp C.L., Li Y., Dietz J.A., Janssen K.T., and Nickells R.W. Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric. BMC Neurosci. 7 (2006) 66
    • (2006) BMC Neurosci. , vol.7 , pp. 66
    • Schlamp, C.L.1    Li, Y.2    Dietz, J.A.3    Janssen, K.T.4    Nickells, R.W.5
  • 63
    • 0024522150 scopus 로고
    • Adult retinal ganglion cells retain the ability to regenerate their axons up to several weeks after axotomy
    • Thanos S., and Vanselow J. Adult retinal ganglion cells retain the ability to regenerate their axons up to several weeks after axotomy. J. Neurosci. Res. 22 (1989) 144-149
    • (1989) J. Neurosci. Res. , vol.22 , pp. 144-149
    • Thanos, S.1    Vanselow, J.2
  • 64
    • 0023752121 scopus 로고
    • Persistent retrograde labeling of adult rat retinal ganglion cells with the carbocyanine dye dil
    • Vidal-Sanz M., Villegas-Pérez M.P., Bray G.M., and Aguayo A.J. Persistent retrograde labeling of adult rat retinal ganglion cells with the carbocyanine dye dil. Exp. Neurol. 102 (1988) 92-101
    • (1988) Exp. Neurol. , vol.102 , pp. 92-101
    • Vidal-Sanz, M.1    Villegas-Pérez, M.P.2    Bray, G.M.3    Aguayo, A.J.4
  • 65
  • 67
    • 0034762293 scopus 로고    scopus 로고
    • Retinal ganglion cell death induced by retinal ischemia. Neuroprotective effects of two alpha-2 agonists
    • Vidal-Sanz M., Lafuente M.P., Mayor S., de Imperial J.M., and Villegas-Pérez M.P. Retinal ganglion cell death induced by retinal ischemia. Neuroprotective effects of two alpha-2 agonists. Surv. Ophthalmol. 45 (2001) 261-267
    • (2001) Surv. Ophthalmol. , vol.45 , pp. 261-267
    • Vidal-Sanz, M.1    Lafuente, M.P.2    Mayor, S.3    de Imperial, J.M.4    Villegas-Pérez, M.P.5
  • 68
    • 70749123595 scopus 로고    scopus 로고
    • Lasering the trabecular meshwork and limbal veins in adult rats results in ocular hypertension and retrograde degeneration of retinal ganglion cells
    • (Abstract)
    • Vidal-Sanz M., Mayor S., Ramírez A.I., Triviño A., Salazar J.J., Ramírez J.M., Salinas M., and Villegas-Pérez M.P. Lasering the trabecular meshwork and limbal veins in adult rats results in ocular hypertension and retrograde degeneration of retinal ganglion cells. Ophthalmic Res. 37 (2005) 48 (Abstract)
    • (2005) Ophthalmic Res. , vol.37 , pp. 48
    • Vidal-Sanz, M.1    Mayor, S.2    Ramírez, A.I.3    Triviño, A.4    Salazar, J.J.5    Ramírez, J.M.6    Salinas, M.7    Villegas-Pérez, M.P.8
  • 70
    • 0027463379 scopus 로고
    • Rapid and protracted phases of retinal ganglion cell loss follow axotomy in the optic nerve of adult rats
    • Villegas-Pérez M.P., Vidal-Sanz M., Rasminsky M., Bray G.M., and Aguayo A.J. Rapid and protracted phases of retinal ganglion cell loss follow axotomy in the optic nerve of adult rats. J. Neurobiol. 24 (1993) 23-36
    • (1993) J. Neurobiol. , vol.24 , pp. 23-36
    • Villegas-Pérez, M.P.1    Vidal-Sanz, M.2    Rasminsky, M.3    Bray, G.M.4    Aguayo, A.J.5
  • 71
    • 10244265974 scopus 로고    scopus 로고
    • Mechanism of retinal ganglion cell loss in inherited retinal dystrophy
    • Villegas-Pérez M.P., Vidal-Sanz M., and Lund R.D. Mechanism of retinal ganglion cell loss in inherited retinal dystrophy. Neuroreport 7 (1996) 1995-1999
    • (1996) Neuroreport , vol.7 , pp. 1995-1999
    • Villegas-Pérez, M.P.1    Vidal-Sanz, M.2    Lund, R.D.3
  • 72
    • 2642619435 scopus 로고    scopus 로고
    • Ganglion cell loss in RCS rat retina: a result of compression of axons by contracting intraretinal vessels linked to the pigment epithelium
    • Villegas-Pérez M.P., Lawrence J.M., Vidal-Sanz M., Lavail M.M., and Lund R.D. Ganglion cell loss in RCS rat retina: a result of compression of axons by contracting intraretinal vessels linked to the pigment epithelium. J. Comp. Neurol. 392 (1998) 58-77
    • (1998) J. Comp. Neurol. , vol.392 , pp. 58-77
    • Villegas-Pérez, M.P.1    Lawrence, J.M.2    Vidal-Sanz, M.3    Lavail, M.M.4    Lund, R.D.5
  • 76
    • 0034754201 scopus 로고    scopus 로고
    • Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension
    • Woldemussie E., Ruiz G., Wijono M., and Wheeler L.A. Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension. Invest. Ophthalmol. Vis. Sci. 42 (2001) 2849-2855
    • (2001) Invest. Ophthalmol. Vis. Sci. , vol.42 , pp. 2849-2855
    • Woldemussie, E.1    Ruiz, G.2    Wijono, M.3    Wheeler, L.A.4
  • 77
    • 3943081270 scopus 로고    scopus 로고
    • Müller cell response to laser-induced increase in intraocular pressure in rats
    • Woldemussie E., Wijono M., and Ruiz G. Müller cell response to laser-induced increase in intraocular pressure in rats. Glia 47 (2004) 109-119
    • (2004) Glia , vol.47 , pp. 109-119
    • Woldemussie, E.1    Wijono, M.2    Ruiz, G.3
  • 78
    • 0019448317 scopus 로고
    • Monoclonal antibodies to mammalian neurofilaments
    • Wood J.N., and Anderton B.H. Monoclonal antibodies to mammalian neurofilaments. Biosci. Rep. 1 (1981) 263-268
    • (1981) Biosci. Rep. , vol.1 , pp. 263-268
    • Wood, J.N.1    Anderton, B.H.2
  • 79
    • 23844451245 scopus 로고    scopus 로고
    • Activation of the extracellular signal-regulated kinase 1/2 pathway by AAV gene transfer protects retinal ganglion cells in glaucoma
    • Zhou Y., Pernet V., Hauswirth W.W., and Di Polo A. Activation of the extracellular signal-regulated kinase 1/2 pathway by AAV gene transfer protects retinal ganglion cells in glaucoma. Mol. Ther. 12 (2005) 402-412
    • (2005) Mol. Ther. , vol.12 , pp. 402-412
    • Zhou, Y.1    Pernet, V.2    Hauswirth, W.W.3    Di Polo, A.4


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