메뉴 건너뛰기




Volumn 33, Issue 4, 2014, Pages 993-1000

MTA family of proteins in DNA damage response: mechanistic insights and potential applications

Author keywords

Chromatin remodeling; DNA damage response; Double strand break repair; Histone modification; Metastasis associated protein; NuRD complex; Therapeutic resistance

Indexed keywords

CELL DNA; CHD3 PROTEIN; CHD4 PROTEIN; DNA BINDING PROTEIN; DOUBLE STRANDED DNA; HISTONE; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE H3; MBD3 PROTEIN; METASTASIS ASSOCIATED PROTEIN; METHYL CPG BINDING PROTEIN 2; NUCLEOSOME REMODELING HISTONE DEACETYLASE; PROTEIN; RETINOBLASTOMA BINDING PROTEIN 7; UNCLASSIFIED DRUG; MTA1 PROTEIN, HUMAN; REPRESSOR PROTEIN;

EID: 84914144739     PISSN: 01677659     EISSN: 15737233     Source Type: Journal    
DOI: 10.1007/s10555-014-9524-2     Document Type: Article
Times cited : (12)

References (113)
  • 1
    • 33847274257 scopus 로고    scopus 로고
    • Metastasis tumor antigens, an emerging family of multifaceted master coregulators
    • COI: 1:CAS:528:DC%2BD2sXkvFehsA%3D%3D, PID: 17142453
    • Manavathi, B., & Kumar, R. (2007). Metastasis tumor antigens, an emerging family of multifaceted master coregulators. Journal of Biological Chemistry, 282, 1529–1533.
    • (2007) Journal of Biological Chemistry , vol.282 , pp. 1529-1533
    • Manavathi, B.1    Kumar, R.2
  • 2
    • 38749123529 scopus 로고    scopus 로고
    • MTA family of coregulators in nuclear receptor biology and pathology
    • PID: 18174918
    • Manavathi, B., Singh, K., & Kumar, R. (2007). MTA family of coregulators in nuclear receptor biology and pathology. Nuclear Receptor Signaling, 5, e010.
    • (2007) Nuclear Receptor Signaling , vol.5 , pp. e010
    • Manavathi, B.1    Singh, K.2    Kumar, R.3
  • 3
    • 84878443103 scopus 로고    scopus 로고
    • Structure and function of the BAH domain in chromatin biology
    • COI: 1:CAS:528:DC%2BC3sXos12gt7Y%3D, PID: 23181513
    • Yang, N., & Xu, R. M. (2013). Structure and function of the BAH domain in chromatin biology. Critical Reviews in Biochemistry and Molecular Biology, 48, 211–221.
    • (2013) Critical Reviews in Biochemistry and Molecular Biology , vol.48 , pp. 211-221
    • Yang, N.1    Xu, R.M.2
  • 4
    • 84862818911 scopus 로고    scopus 로고
    • The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome
    • COI: 1:CAS:528:DC%2BC38Xjtlyisrc%3D, PID: 22398447
    • Kuo, A. J., Song, J., Cheung, P., Ishibe-Murakami, S., Yamazoe, S., Chen, J. K., et al. (2012). The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome. Nature, 484, 115–119.
    • (2012) Nature , vol.484 , pp. 115-119
    • Kuo, A.J.1    Song, J.2    Cheung, P.3    Ishibe-Murakami, S.4    Yamazoe, S.5    Chen, J.K.6
  • 5
    • 37349033583 scopus 로고    scopus 로고
    • Role of the conserved Sir3-BAH domain in nucleosome binding and silent chromatin assembly
    • COI: 1:CAS:528:DC%2BD1cXksFyitg%3D%3D, PID: 18158899
    • Onishi, M., Liou, G. G., Buchberger, J. R., Walz, T., & Moazed, D. (2007). Role of the conserved Sir3-BAH domain in nucleosome binding and silent chromatin assembly. Molecular Cell, 28, 1015–1028.
    • (2007) Molecular Cell , vol.28 , pp. 1015-1028
    • Onishi, M.1    Liou, G.G.2    Buchberger, J.R.3    Walz, T.4    Moazed, D.5
  • 6
    • 44649140352 scopus 로고    scopus 로고
    • Atrophin recruits HDAC1/2 and G9a to modify histone H3K9 and to determine cell fates
    • COI: 1:CAS:528:DC%2BD1cXmsFykt7g%3D, PID: 18451879
    • Wang, L., Charroux, B., Kerridge, S., & Tsai, C. C. (2008). Atrophin recruits HDAC1/2 and G9a to modify histone H3K9 and to determine cell fates. EMBO Reports, 9, 555–562.
    • (2008) EMBO Reports , vol.9 , pp. 555-562
    • Wang, L.1    Charroux, B.2    Kerridge, S.3    Tsai, C.C.4
  • 7
    • 0037215484 scopus 로고    scopus 로고
    • Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain
    • COI: 1:CAS:528:DC%2BD3sXhtVOkuw%3D%3D
    • Ding, Z., Gillespie, L. L., & Paterno, G. D. (2003). Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain. Molecular Cell. Biology, 23, 250–258.
    • (2003) Molecular Cell. Biology , vol.23 , pp. 250-258
    • Ding, Z.1    Gillespie, L.L.2    Paterno, G.D.3
  • 8
    • 84893342506 scopus 로고    scopus 로고
    • Nuclear localization of the transcriptional regulator MIER1alpha requires interaction with HDAC1/2 in breast cancer cells
    • PID: 24376786
    • Li, S., Paterno, G. D., & Gillespie, L. L. (2013). Nuclear localization of the transcriptional regulator MIER1alpha requires interaction with HDAC1/2 in breast cancer cells. PLoS One, 8, e84046.
    • (2013) PLoS One , vol.8 , pp. e84046
    • Li, S.1    Paterno, G.D.2    Gillespie, L.L.3
  • 9
    • 85047671736 scopus 로고    scopus 로고
    • The SANT domain: a putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional co-repressor N-CoR and TFIIIB
    • COI: 1:CAS:528:DyaK28Xhsl2htrY%3D, PID: 8882580
    • Aasland, R., Stewart, A. F., & Gibson, T. (1996). The SANT domain: a putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional co-repressor N-CoR and TFIIIB. Trends in Biochemical Sciences, 21, 87–88.
    • (1996) Trends in Biochemical Sciences , vol.21 , pp. 87-88
    • Aasland, R.1    Stewart, A.F.2    Gibson, T.3
  • 10
    • 0036809731 scopus 로고    scopus 로고
    • Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes
    • COI: 1:CAS:528:DC%2BD38XosF2rur0%3D, PID: 12419236
    • Boyer, L. A., Langer, M. R., Crowley, K. A., Tan, S., Denu, J. M., & Peterson, C. L. (2002). Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes. Molecular Cell, 10, 935–942.
    • (2002) Molecular Cell , vol.10 , pp. 935-942
    • Boyer, L.A.1    Langer, M.R.2    Crowley, K.A.3    Tan, S.4    Denu, J.M.5    Peterson, C.L.6
  • 11
    • 0037925529 scopus 로고    scopus 로고
    • A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation
    • COI: 1:CAS:528:DC%2BD3sXltFyhtLc%3D, PID: 12840002
    • Yu, J., Li, Y., Ishizuka, T., Guenther, M. G., & Lazar, M. A. (2003). A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation. EMBO Journal, 22, 3403–3410.
    • (2003) EMBO Journal , vol.22 , pp. 3403-3410
    • Yu, J.1    Li, Y.2    Ishizuka, T.3    Guenther, M.G.4    Lazar, M.A.5
  • 12
    • 0742305878 scopus 로고    scopus 로고
    • The SANT domain: a unique histone-tail-binding module?
    • COI: 1:CAS:528:DC%2BD2cXnsFOjsA%3D%3D, PID: 15040448
    • Boyer, L. A., Latek, R. R., & Peterson, C. L. (2004). The SANT domain: a unique histone-tail-binding module? Nature Reviews Molecular Cell Biology, 5, 158–163.
    • (2004) Nature Reviews Molecular Cell Biology , vol.5 , pp. 158-163
    • Boyer, L.A.1    Latek, R.R.2    Peterson, C.L.3
  • 13
    • 34547856653 scopus 로고    scopus 로고
    • The human Mi-2/NuRD complex and gene regulation
    • COI: 1:CAS:528:DC%2BD2sXovFeku7c%3D, PID: 17694084
    • Denslow, S. A., & Wade, P. A. (2007). The human Mi-2/NuRD complex and gene regulation. Oncogene, 26, 5433–5438.
    • (2007) Oncogene , vol.26 , pp. 5433-5438
    • Denslow, S.A.1    Wade, P.A.2
  • 14
    • 84862915067 scopus 로고    scopus 로고
    • Metastasis-associated protein 1/nucleosome remodeling and histone deacetylase complex in cancer
    • COI: 1:CAS:528:DC%2BC38Xos1KlsQ%3D%3D, PID: 22253283
    • Li, D. Q., Pakala, S. B., Nair, S. S., Eswaran, J., & Kumar, R. (2012). Metastasis-associated protein 1/nucleosome remodeling and histone deacetylase complex in cancer. Cancer Research, 72, 387–394.
    • (2012) Cancer Research , vol.72 , pp. 387-394
    • Li, D.Q.1    Pakala, S.B.2    Nair, S.S.3    Eswaran, J.4    Kumar, R.5
  • 15
    • 79960844248 scopus 로고    scopus 로고
    • Cancer biology and NuRD: a multifaceted chromatin remodelling complex
    • COI: 1:CAS:528:DC%2BC3MXos1Srsro%3D, PID: 21734722
    • Lai, A. Y., & Wade, P. A. (2011). Cancer biology and NuRD: a multifaceted chromatin remodelling complex. Nature Reviews Cancer, 11, 588–596.
    • (2011) Nature Reviews Cancer , vol.11 , pp. 588-596
    • Lai, A.Y.1    Wade, P.A.2
  • 16
    • 78649349810 scopus 로고    scopus 로고
    • A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage
    • COI: 1:CAS:528:DC%2BC3cXhtl2ktrrO, PID: 20937877
    • Chou, D. M., Adamson, B., Dephoure, N. E., Tan, X., Nottke, A. C., Hurov, K. E., et al. (2010). A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage. Proceedings of the National Academy of Sciences of the United States of America, 107, 18475–18480.
    • (2010) Proceedings of the National Academy of Sciences of the United States of America , vol.107 , pp. 18475-18480
    • Chou, D.M.1    Adamson, B.2    Dephoure, N.E.3    Tan, X.4    Nottke, A.C.5    Hurov, K.E.6
  • 18
    • 77953595234 scopus 로고    scopus 로고
    • Mi-2/NuRD complex making inroads into DNA-damage response pathway
    • COI: 1:CAS:528:DC%2BC3cXht12kurzF, PID: 20505336
    • Li, D. Q., & Kumar, R. (2010). Mi-2/NuRD complex making inroads into DNA-damage response pathway. Cell Cycle, 9, 2071–2079.
    • (2010) Cell Cycle , vol.9 , pp. 2071-2079
    • Li, D.Q.1    Kumar, R.2
  • 20
    • 77953584693 scopus 로고    scopus 로고
    • Requirement of MTA1 in ATR-mediated DNA damage checkpoint function
    • COI: 1:CAS:528:DC%2BC3cXnsFygs7o%3D, PID: 20427275
    • Li, D. Q., Ohshiro, K., Khan, M. N., & Kumar, R. (2010). Requirement of MTA1 in ATR-mediated DNA damage checkpoint function. Journal of Biological Chemistry, 285(26), 19802–19812.
    • (2010) Journal of Biological Chemistry , vol.285 , Issue.26 , pp. 19802-19812
    • Li, D.Q.1    Ohshiro, K.2    Khan, M.N.3    Kumar, R.4
  • 21
    • 77951219163 scopus 로고    scopus 로고
    • Revelation of p53-independent function of MTA1 in DNA damage response via modulation of the p21 WAF1-proliferating cell nuclear antigen pathway
    • COI: 1:CAS:528:DC%2BC3cXjsFehsrg%3D, PID: 20071335
    • Li, D. Q., Pakala, S. B., Reddy, S. D., Ohshiro, K., Peng, S. H., Lian, Y., et al. (2010). Revelation of p53-independent function of MTA1 in DNA damage response via modulation of the p21 WAF1-proliferating cell nuclear antigen pathway. Journal of Biological Chemistry, 285(13), 10044–10052.
    • (2010) Journal of Biological Chemistry , vol.285 , Issue.13 , pp. 10044-10052
    • Li, D.Q.1    Pakala, S.B.2    Reddy, S.D.3    Ohshiro, K.4    Peng, S.H.5    Lian, Y.6
  • 22
    • 77956387556 scopus 로고    scopus 로고
    • The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage
    • COI: 1:CAS:528:DC%2BC3cXhtFyhu7fN, PID: 20805320
    • Smeenk, G., Wiegant, W. W., Vrolijk, H., Solari, A. P., Pastink, A., & van Attikum, H. (2010). The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage. Journal of Cell Biology, 190, 741–749.
    • (2010) Journal of Cell Biology , vol.190 , pp. 741-749
    • Smeenk, G.1    Wiegant, W.W.2    Vrolijk, H.3    Solari, A.P.4    Pastink, A.5    van Attikum, H.6
  • 23
    • 84861960862 scopus 로고    scopus 로고
    • Close encounters of the RNF8th kind: when chromatin meets DNA repair
    • COI: 1:CAS:528:DC%2BC38XltVartLg%3D, PID: 22464734
    • Luijsterburg, M. S., & van Attikum, H. (2012). Close encounters of the RNF8th kind: when chromatin meets DNA repair. Current Opinion in Cell Biology, 24, 439–447.
    • (2012) Current Opinion in Cell Biology , vol.24 , pp. 439-447
    • Luijsterburg, M.S.1    van Attikum, H.2
  • 24
    • 79955034796 scopus 로고    scopus 로고
    • Heterochromatin and the DNA damage response: the need to relax
    • COI: 1:CAS:528:DC%2BC3cXhtlahu7zK
    • Cann, K. L., & Dellaire, G. (2011). Heterochromatin and the DNA damage response: the need to relax. Biochemical Cell Biology, 89, 45–60.
    • (2011) Biochemical Cell Biology , vol.89 , pp. 45-60
    • Cann, K.L.1    Dellaire, G.2
  • 25
    • 84882630603 scopus 로고    scopus 로고
    • SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling
    • COI: 1:CAS:528:DC%2BC3sXht1Wrur7F, PID: 23911928
    • Toiber, D., Erdel, F., Bouazoune, K., Silberman, D. M., Zhong, L., Mulligan, P., et al. (2013). SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling. Molecular Cell, 51, 454–468.
    • (2013) Molecular Cell , vol.51 , pp. 454-468
    • Toiber, D.1    Erdel, F.2    Bouazoune, K.3    Silberman, D.M.4    Zhong, L.5    Mulligan, P.6
  • 26
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • COI: 1:CAS:528:DC%2BD1MXhtlGktLrK, PID: 19847258
    • Jackson, S. P., & Bartek, J. (2009). The DNA-damage response in human biology and disease. Nature, 461(7267), 1071–1078.
    • (2009) Nature , vol.461 , Issue.7267 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 27
    • 36749022214 scopus 로고    scopus 로고
    • The DNA damage response: ten years after
    • COI: 1:CAS:528:DC%2BD1cXktVWisQ%3D%3D, PID: 18082599
    • Harper, J. W., & Elledge, S. J. (2007). The DNA damage response: ten years after. Molecular Cell, 28, 739–745.
    • (2007) Molecular Cell , vol.28 , pp. 739-745
    • Harper, J.W.1    Elledge, S.J.2
  • 28
    • 29244434544 scopus 로고    scopus 로고
    • MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
    • COI: 1:CAS:528:DC%2BD28XktlWisA%3D%3D, PID: 16377563
    • Stucki, M., Clapperton, J. A., Mohammad, D., Yaffe, M. B., Smerdon, S. J., & Jackson, S. P. (2005). MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell, 123, 1213–1226.
    • (2005) Cell , vol.123 , pp. 1213-1226
    • Stucki, M.1    Clapperton, J.A.2    Mohammad, D.3    Yaffe, M.B.4    Smerdon, S.J.5    Jackson, S.P.6
  • 29
    • 47549105301 scopus 로고    scopus 로고
    • Acetylated lysine 56 on histone H3 drives chromatin assembly after repair and signals for the completion of repair
    • COI: 1:CAS:528:DC%2BD1cXptlaltbY%3D, PID: 18662539
    • Chen, C. C., Carson, J. J., Feser, J., Tamburini, B., Zabaronick, S., Linger, J., et al. (2008). Acetylated lysine 56 on histone H3 drives chromatin assembly after repair and signals for the completion of repair. Cell, 134, 231–243.
    • (2008) Cell , vol.134 , pp. 231-243
    • Chen, C.C.1    Carson, J.J.2    Feser, J.3    Tamburini, B.4    Zabaronick, S.5    Linger, J.6
  • 30
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • COI: 1:CAS:528:DC%2BC3MXjsFeqtrk%3D, PID: 21376230
    • Hanahan, D., & Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. Cell, 144, 646–674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 31
    • 0037567268 scopus 로고    scopus 로고
    • Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
    • COI: 1:CAS:528:DC%2BD3sXktlKrtbk%3D, PID: 12791985
    • Zou, L., & Elledge, S. J. (2003). Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science, 300, 1542–1548.
    • (2003) Science , vol.300 , pp. 1542-1548
    • Zou, L.1    Elledge, S.J.2
  • 32
    • 21244456772 scopus 로고    scopus 로고
    • Complicated tails: histone modifications and the DNA damage response
    • COI: 1:CAS:528:DC%2BD2MXmtF2nsb0%3D, PID: 15989948
    • Vidanes, G. M., Bonilla, C. Y., & Toczyski, D. P. (2005). Complicated tails: histone modifications and the DNA damage response. Cell, 121, 973–976.
    • (2005) Cell , vol.121 , pp. 973-976
    • Vidanes, G.M.1    Bonilla, C.Y.2    Toczyski, D.P.3
  • 33
    • 78649336706 scopus 로고    scopus 로고
    • The DNA damage response: making it safe to play with knives
    • COI: 1:CAS:528:DC%2BC3cXhtlCjtr7P, PID: 20965415
    • Ciccia, A., & Elledge, S. J. (2010). The DNA damage response: making it safe to play with knives. Molecular Cell, 40, 179–204.
    • (2010) Molecular Cell , vol.40 , pp. 179-204
    • Ciccia, A.1    Elledge, S.J.2
  • 34
    • 63249124451 scopus 로고    scopus 로고
    • Chromatin remodeling finds its place in the DNA double-strand break response
    • COI: 1:CAS:528:DC%2BD1MXjsV2ksbw%3D, PID: 19139074
    • Pandita, T. K., & Richardson, C. (2009). Chromatin remodeling finds its place in the DNA double-strand break response. Nucleic Acids Research, 37, 1363–1377.
    • (2009) Nucleic Acids Research , vol.37 , pp. 1363-1377
    • Pandita, T.K.1    Richardson, C.2
  • 35
    • 84866741381 scopus 로고    scopus 로고
    • Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer
    • COI: 1:CAS:528:DC%2BC38XhtlWns7rP, PID: 22952011
    • Sulli, G., Di Micco, R., & d’Adda di Fagagna, F. (2012). Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer. Nature Reviews Cancer, 12, 709–720.
    • (2012) Nature Reviews Cancer , vol.12 , pp. 709-720
    • Sulli, G.1    Di Micco, R.2    d’Adda di Fagagna, F.3
  • 36
    • 78951474460 scopus 로고    scopus 로고
    • The MRE11 complex: starting from the ends
    • COI: 1:CAS:528:DC%2BC3MXotlSgsA%3D%3D, PID: 21252998
    • Stracker, T. H., & Petrini, J. H. (2011). The MRE11 complex: starting from the ends. Nature Reviews Molecular Cell Biology, 12, 90–103.
    • (2011) Nature Reviews Molecular Cell Biology , vol.12 , pp. 90-103
    • Stracker, T.H.1    Petrini, J.H.2
  • 37
    • 3242887431 scopus 로고    scopus 로고
    • Dial 9-1-1 for DNA damage: the Rad9-Hus1-Rad1 (9-1-1) clamp complex
    • COI: 1:CAS:528:DC%2BD2cXmtVeqt78%3D
    • Parrilla-Castellar, E. R., Arlander, S. J., & Karnitz, L. (2004). Dial 9-1-1 for DNA damage: the Rad9-Hus1-Rad1 (9-1-1) clamp complex. DNA Repair (Amst), 3, 1009–1014.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 1009-1014
    • Parrilla-Castellar, E.R.1    Arlander, S.J.2    Karnitz, L.3
  • 38
    • 1842431822 scopus 로고    scopus 로고
    • Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex
    • COI: 1:CAS:528:DC%2BD2cXis1ant74%3D, PID: 15064416
    • Lee, J. H., & Paull, T. T. (2004). Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex. Science, 304, 93–96.
    • (2004) Science , vol.304 , pp. 93-96
    • Lee, J.H.1    Paull, T.T.2
  • 39
    • 34547571752 scopus 로고    scopus 로고
    • Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses
    • COI: 1:CAS:528:DC%2BD2sXptlynur8%3D, PID: 17693258
    • Morrison, A. J., Kim, J. A., Person, M. D., Highland, J., Xiao, J., Wehr, T. S., et al. (2007). Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses. Cell, 130, 499–511.
    • (2007) Cell , vol.130 , pp. 499-511
    • Morrison, A.J.1    Kim, J.A.2    Person, M.D.3    Highland, J.4    Xiao, J.5    Wehr, T.S.6
  • 40
    • 17644409069 scopus 로고    scopus 로고
    • ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
    • COI: 1:CAS:528:DC%2BD2MXjtlOjt7k%3D, PID: 15790808
    • Lee, J. H., & Paull, T. T. (2005). ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex. Science, 308, 551–554.
    • (2005) Science , vol.308 , pp. 551-554
    • Lee, J.H.1    Paull, T.T.2
  • 41
    • 84875423827 scopus 로고    scopus 로고
    • The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
    • COI: 1:CAS:528:DC%2BC3sXjvVers7Y%3D
    • Shiloh, Y., & Ziv, Y. (2013). The ATM protein kinase: regulating the cellular response to genotoxic stress, and more. Nature Reviews Molecular Cell Biology, 14, 197–210.
    • (2013) Nature Reviews Molecular Cell Biology , vol.14 , pp. 197-210
    • Shiloh, Y.1    Ziv, Y.2
  • 42
    • 47749141560 scopus 로고    scopus 로고
    • ATR: an essential regulator of genome integrity
    • COI: 1:CAS:528:DC%2BD1cXosl2rsb0%3D, PID: 18594563
    • Cimprich, K. A., & Cortez, D. (2008). ATR: an essential regulator of genome integrity. Nature Reviews Molecular Cell Biology, 9, 616–627.
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , pp. 616-627
    • Cimprich, K.A.1    Cortez, D.2
  • 43
    • 15844394846 scopus 로고    scopus 로고
    • Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
    • COI: 1:CAS:528:DC%2BD2MXislCmsL4%3D, PID: 15758953
    • Falck, J., Coates, J., & Jackson, S. P. (2005). Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature, 434, 605–611.
    • (2005) Nature , vol.434 , pp. 605-611
    • Falck, J.1    Coates, J.2    Jackson, S.P.3
  • 44
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: safeguarding genome integrity
    • COI: 1:CAS:528:DC%2BD3sXhsFGhtr4%3D, PID: 12612651
    • Shiloh, Y. (2003). ATM and related protein kinases: safeguarding genome integrity. Nature Reviews Cancer, 3, 155–168.
    • (2003) Nature Reviews Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 45
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • COI: 1:CAS:528:DyaK1cXhsleiu7g%3D, PID: 9488723
    • Rogakou, E. P., Pilch, D. R., Orr, A. H., Ivanova, V. S., & Bonner, W. M. (1998). DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. Journal of Biological Chemistry, 273, 5858–5868.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 46
    • 1942538492 scopus 로고    scopus 로고
    • ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation
    • COI: 1:CAS:528:DC%2BD2cXis1yjtLo%3D, PID: 15059890
    • Stiff, T., O’Driscoll, M., Rief, N., Iwabuchi, K., Lobrich, M., & Jeggo, P. A. (2004). ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Research, 64, 2390–2396.
    • (2004) Cancer Research , vol.64 , pp. 2390-2396
    • Stiff, T.1    O’Driscoll, M.2    Rief, N.3    Iwabuchi, K.4    Lobrich, M.5    Jeggo, P.A.6
  • 47
    • 0035930537 scopus 로고    scopus 로고
    • Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress
    • COI: 1:CAS:528:DC%2BD38XkvFWj, PID: 11673449
    • Ward, I. M., & Chen, J. (2001). Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress. Journal of Biological Chemistry, 276, 47759–47762.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 47759-47762
    • Ward, I.M.1    Chen, J.2
  • 48
    • 33748923466 scopus 로고    scopus 로고
    • Spatio-temporal dynamics of chromatin containing DNA breaks
    • COI: 1:CAS:528:DC%2BD28XhtlWqsLvO, PID: 16929171
    • Kruhlak, M. J., Celeste, A., & Nussenzweig, A. (2006). Spatio-temporal dynamics of chromatin containing DNA breaks. Cell Cycle, 5, 1910–1912.
    • (2006) Cell Cycle , vol.5 , pp. 1910-1912
    • Kruhlak, M.J.1    Celeste, A.2    Nussenzweig, A.3
  • 49
    • 55249116558 scopus 로고    scopus 로고
    • Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin
    • COI: 1:CAS:528:DC%2BD1MXisFOksg%3D%3D, PID: 18772227
    • Kinner, A., Wu, W., Staudt, C., & Iliakis, G. (2008). Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin. Nucleic Acids Research, 36, 5678–5694.
    • (2008) Nucleic Acids Research , vol.36 , pp. 5678-5694
    • Kinner, A.1    Wu, W.2    Staudt, C.3    Iliakis, G.4
  • 50
    • 84863001577 scopus 로고    scopus 로고
    • Prime, repair, restore: the active role of chromatin in the DNA damage response
    • COI: 1:CAS:528:DC%2BC38XpsVOru78%3D, PID: 22749398
    • Soria, G., Polo, S. E., & Almouzni, G. (2012). Prime, repair, restore: the active role of chromatin in the DNA damage response. Molecular Cell, 46, 722–734.
    • (2012) Molecular Cell , vol.46 , pp. 722-734
    • Soria, G.1    Polo, S.E.2    Almouzni, G.3
  • 51
    • 0343280013 scopus 로고    scopus 로고
    • A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
    • COI: 1:CAS:528:DC%2BD3cXlsFCmtLk%3D, PID: 10959836
    • Paull, T. T., Rogakou, E. P., Yamazaki, V., Kirchgessner, C. U., Gellert, M., & Bonner, W. M. (2000). A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Current Biology, 10, 886–895.
    • (2000) Current Biology , vol.10 , pp. 886-895
    • Paull, T.T.1    Rogakou, E.P.2    Yamazaki, V.3    Kirchgessner, C.U.4    Gellert, M.5    Bonner, W.M.6
  • 52
    • 10944224673 scopus 로고    scopus 로고
    • INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair
    • COI: 1:CAS:528:DC%2BD2MXmsFyl, PID: 15607974
    • Morrison, A. J., Highland, J., Krogan, N. J., Arbel-Eden, A., Greenblatt, J. F., Haber, J. E., et al. (2004). INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. Cell, 119, 767–775.
    • (2004) Cell , vol.119 , pp. 767-775
    • Morrison, A.J.1    Highland, J.2    Krogan, N.J.3    Arbel-Eden, A.4    Greenblatt, J.F.5    Haber, J.E.6
  • 53
    • 10944233962 scopus 로고    scopus 로고
    • Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair
    • PID: 15607975
    • van Attikum, H., Fritsch, O., Hohn, B., & Gasser, S. M. (2004). Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair. Cell, 119, 777–788.
    • (2004) Cell , vol.119 , pp. 777-788
    • van Attikum, H.1    Fritsch, O.2    Hohn, B.3    Gasser, S.M.4
  • 54
    • 33846604273 scopus 로고    scopus 로고
    • HP1 proteins are essential for a dynamic nuclear response that rescues the function of perturbed heterochromatin in primary human cells
    • COI: 1:CAS:528:DC%2BD2sXhtFGhtLk%3D
    • Zhang, R., Liu, S. T., Chen, W., Bonner, M., Pehrson, J., Yen, T. J., et al. (2007). HP1 proteins are essential for a dynamic nuclear response that rescues the function of perturbed heterochromatin in primary human cells. Molecular Cell. Biology, 27, 949–962.
    • (2007) Molecular Cell. Biology , vol.27 , pp. 949-962
    • Zhang, R.1    Liu, S.T.2    Chen, W.3    Bonner, M.4    Pehrson, J.5    Yen, T.J.6
  • 55
    • 34748902384 scopus 로고    scopus 로고
    • Global chromatin compaction limits the strength of the DNA damage response
    • COI: 1:CAS:528:DC%2BD2sXhtFahsr7F, PID: 17893239
    • Murga, M., Jaco, I., Fan, Y., Soria, R., Martinez-Pastor, B., Cuadrado, M., et al. (2007). Global chromatin compaction limits the strength of the DNA damage response. Journal of Cell Biology, 178, 1101–1108.
    • (2007) Journal of Cell Biology , vol.178 , pp. 1101-1108
    • Murga, M.1    Jaco, I.2    Fan, Y.3    Soria, R.4    Martinez-Pastor, B.5    Cuadrado, M.6
  • 56
    • 77957738825 scopus 로고    scopus 로고
    • The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair
    • COI: 1:CAS:528:DC%2BC3cXht12isLjP, PID: 20876283
    • Xu, Y., Sun, Y., Jiang, X., Ayrapetov, M. K., Moskwa, P., Yang, S., et al. (2010). The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair. Journal of Cell Biology, 191, 31–43.
    • (2010) Journal of Cell Biology , vol.191 , pp. 31-43
    • Xu, Y.1    Sun, Y.2    Jiang, X.3    Ayrapetov, M.K.4    Moskwa, P.5    Yang, S.6
  • 58
    • 33746601439 scopus 로고    scopus 로고
    • Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway
    • COI: 1:CAS:528:DC%2BD28XnsFWqurg%3D, PID: 16862143
    • Ziv, Y., Bielopolski, D., Galanty, Y., Lukas, C., Taya, Y., Schultz, D. C., et al. (2006). Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway. Nature Cell Biology, 8, 870–876.
    • (2006) Nature Cell Biology , vol.8 , pp. 870-876
    • Ziv, Y.1    Bielopolski, D.2    Galanty, Y.3    Lukas, C.4    Taya, Y.5    Schultz, D.C.6
  • 59
    • 84875198804 scopus 로고    scopus 로고
    • Chromatin remodeling at DNA double-strand breaks
    • COI: 1:CAS:528:DC%2BC3sXktFakt7w%3D, PID: 23498941
    • Price, B. D., & D’Andrea, A. D. (2013). Chromatin remodeling at DNA double-strand breaks. Cell, 152, 1344–1354.
    • (2013) Cell , vol.152 , pp. 1344-1354
    • Price, B.D.1    D’Andrea, A.D.2
  • 60
    • 34247172850 scopus 로고    scopus 로고
    • Histone modifications in response to DNA damage
    • COI: 1:CAS:528:DC%2BD2sXksFahurY%3D, PID: 17306843
    • Altaf, M., Saksouk, N., & Cote, J. (2007). Histone modifications in response to DNA damage. Mutation Research, 618, 81–90.
    • (2007) Mutation Research , vol.618 , pp. 81-90
    • Altaf, M.1    Saksouk, N.2    Cote, J.3
  • 61
    • 79959947909 scopus 로고    scopus 로고
    • Chromatin response to DNA double-strand break damage
    • COI: 1:CAS:528:DC%2BC3MXotlCjsb8%3D, PID: 22122340
    • Bao, Y. (2011). Chromatin response to DNA double-strand break damage. Epigenomics, 3, 307–321.
    • (2011) Epigenomics , vol.3 , pp. 307-321
    • Bao, Y.1
  • 62
    • 66349130703 scopus 로고    scopus 로고
    • Chromatin dynamics coupled to DNA repair
    • COI: 1:CAS:528:DC%2BD1MXovF2jt7Y%3D, PID: 19218832
    • Huertas, D., Sendra, R., & Munoz, P. (2009). Chromatin dynamics coupled to DNA repair. Epigenetics, 4, 31–42.
    • (2009) Epigenetics , vol.4 , pp. 31-42
    • Huertas, D.1    Sendra, R.2    Munoz, P.3
  • 63
    • 84875085285 scopus 로고    scopus 로고
    • Connecting chromatin modifying factors to DNA damage response
    • COI: 1:CAS:528:DC%2BC3sXitFKisLk%3D, PID: 23348929
    • Lai, W., Li, H., Liu, S., & Tao, Y. (2013). Connecting chromatin modifying factors to DNA damage response. International Journal of Molecular Sciences, 14, 2355–2369.
    • (2013) International Journal of Molecular Sciences , vol.14 , pp. 2355-2369
    • Lai, W.1    Li, H.2    Liu, S.3    Tao, Y.4
  • 64
    • 84856278412 scopus 로고    scopus 로고
    • ATP-dependent chromatin remodeling in the DNA-damage response
    • COI: 1:CAS:528:DC%2BC38Xjt1Krt74%3D
    • Lans, H., Marteijn, J. A., & Vermeulen, W. (2012). ATP-dependent chromatin remodeling in the DNA-damage response. Epigenetics & Chromatin, 5, 4.
    • (2012) Epigenetics & Chromatin , vol.5 , pp. 4
    • Lans, H.1    Marteijn, J.A.2    Vermeulen, W.3
  • 65
    • 80052146061 scopus 로고    scopus 로고
    • Chromatin and the DNA damage response: the cancer connection
    • COI: 1:CAS:528:DC%2BC3MXhtVyqtL7F, PID: 21782533
    • Luijsterburg, M. S., & van Attikum, H. (2011). Chromatin and the DNA damage response: the cancer connection. Molecular Oncology, 5, 349–367.
    • (2011) Molecular Oncology , vol.5 , pp. 349-367
    • Luijsterburg, M.S.1    van Attikum, H.2
  • 67
    • 84878918708 scopus 로고    scopus 로고
    • The chromatin response to DNA breaks: leaving a mark on genome integrity
    • COI: 1:CAS:528:DC%2BC3sXhtFOqsrzM, PID: 23414304
    • Smeenk, G., & van Attikum, H. (2013). The chromatin response to DNA breaks: leaving a mark on genome integrity. Annual Review of Biochemistry, 82, 55–80.
    • (2013) Annual Review of Biochemistry , vol.82 , pp. 55-80
    • Smeenk, G.1    van Attikum, H.2
  • 68
    • 33748367886 scopus 로고    scopus 로고
    • Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction
    • COI: 1:CAS:528:DC%2BD28XptFWisLw%3D, PID: 16932743
    • Park, J. H., Park, E. J., Lee, H. S., Kim, S. J., Hur, S. K., Imbalzano, A. N., et al. (2006). Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction. EMBO Journal, 25, 3986–3997.
    • (2006) EMBO Journal , vol.25 , pp. 3986-3997
    • Park, J.H.1    Park, E.J.2    Lee, H.S.3    Kim, S.J.4    Hur, S.K.5    Imbalzano, A.N.6
  • 69
    • 67650725820 scopus 로고    scopus 로고
    • The biology of chromatin remodeling complexes
    • COI: 1:CAS:528:DC%2BD1MXos1Ghtbg%3D, PID: 19355820
    • Clapier, C. R., & Cairns, B. R. (2009). The biology of chromatin remodeling complexes. Annual Review of Biochemistry, 78, 273–304.
    • (2009) Annual Review of Biochemistry , vol.78 , pp. 273-304
    • Clapier, C.R.1    Cairns, B.R.2
  • 70
    • 0033994292 scopus 로고    scopus 로고
    • ATP-dependent chromatin-remodeling complexes
    • COI: 1:CAS:528:DC%2BD3cXhsVKms7c%3D
    • Vignali, M., Hassan, A. H., Neely, K. E., & Workman, J. L. (2000). ATP-dependent chromatin-remodeling complexes. Molecular Cell. Biology, 20, 1899–1910.
    • (2000) Molecular Cell. Biology , vol.20 , pp. 1899-1910
    • Vignali, M.1    Hassan, A.H.2    Neely, K.E.3    Workman, J.L.4
  • 71
    • 34247465955 scopus 로고    scopus 로고
    • SnapShot: chromatin remodeling complexes
    • COI: 1:CAS:528:DC%2BD2sXlvVGkurs%3D, PID: 17482554
    • Bao, Y., & Shen, X. (2007). SnapShot: chromatin remodeling complexes. Cell, 129, 632.
    • (2007) Cell , vol.129 , pp. 632
    • Bao, Y.1    Shen, X.2
  • 72
    • 33748272677 scopus 로고    scopus 로고
    • Interplay between Ino80 and Swr1 chromatin remodeling enzymes regulates cell cycle checkpoint adaptation in response to DNA damage
    • COI: 1:CAS:528:DC%2BD28XptlSnt7g%3D, PID: 16951256
    • Papamichos-Chronakis, M., Krebs, J. E., & Peterson, C. L. (2006). Interplay between Ino80 and Swr1 chromatin remodeling enzymes regulates cell cycle checkpoint adaptation in response to DNA damage. Genes and Development, 20, 2437–2449.
    • (2006) Genes and Development , vol.20 , pp. 2437-2449
    • Papamichos-Chronakis, M.1    Krebs, J.E.2    Peterson, C.L.3
  • 73
    • 34547907083 scopus 로고    scopus 로고
    • RSC functions as an early double-strand-break sensor in the cell’s response to DNA damage
    • COI: 1:CAS:528:DC%2BD2sXpt1Knsrk%3D, PID: 17689960
    • Liang, B., Qiu, J., Ratnakumar, K., & Laurent, B. C. (2007). RSC functions as an early double-strand-break sensor in the cell’s response to DNA damage. Current Biology, 17, 1432–1437.
    • (2007) Current Biology , vol.17 , pp. 1432-1437
    • Liang, B.1    Qiu, J.2    Ratnakumar, K.3    Laurent, B.C.4
  • 74
    • 84884557189 scopus 로고    scopus 로고
    • Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage
    • COI: 1:CAS:528:DC%2BC3sXhslertrnL, PID: 24029917
    • Seeber, A., Dion, V., & Gasser, S. M. (2013). Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage. Genes and Development, 27, 1999–2008.
    • (2013) Genes and Development , vol.27 , pp. 1999-2008
    • Seeber, A.1    Dion, V.2    Gasser, S.M.3
  • 75
    • 33645228528 scopus 로고    scopus 로고
    • Increased DNA damage sensitivity and apoptosis in cells lacking the Snf5/Ini1 subunit of the SWI/SNF chromatin remodeling complex
    • COI: 1:CAS:528:DC%2BD28XivFSrtrw%3D
    • Klochendler-Yeivin, A., Picarsky, E., & Yaniv, M. (2006). Increased DNA damage sensitivity and apoptosis in cells lacking the Snf5/Ini1 subunit of the SWI/SNF chromatin remodeling complex. Molecular Cell. Biology, 26, 2661–2674.
    • (2006) Molecular Cell. Biology , vol.26 , pp. 2661-2674
    • Klochendler-Yeivin, A.1    Picarsky, E.2    Yaniv, M.3
  • 76
    • 56549100855 scopus 로고    scopus 로고
    • Mammalian SWI/SNF chromatin remodeling complexes are required to prevent apoptosis after DNA damage
    • COI: 1:CAS:528:DC%2BD1cXhsVCmsr7J
    • Park, J. H., Park, E. J., Hur, S. K., Kim, S., & Kwon, J. (2009). Mammalian SWI/SNF chromatin remodeling complexes are required to prevent apoptosis after DNA damage. DNA Repair (Amst), 8, 29–39.
    • (2009) DNA Repair (Amst) , vol.8 , pp. 29-39
    • Park, J.H.1    Park, E.J.2    Hur, S.K.3    Kim, S.4    Kwon, J.5
  • 77
    • 34648834736 scopus 로고    scopus 로고
    • Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double-strand breaks
    • PID: 17762868
    • van Attikum, H., Fritsch, O., & Gasser, S. M. (2007). Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double-strand breaks. EMBO Journal, 26, 4113–4125.
    • (2007) EMBO Journal , vol.26 , pp. 4113-4125
    • van Attikum, H.1    Fritsch, O.2    Gasser, S.M.3
  • 78
    • 23044479628 scopus 로고    scopus 로고
    • Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair
    • COI: 1:CAS:528:DC%2BD2MXmslGhtbY%3D, PID: 16024655
    • Chai, B., Huang, J., Cairns, B. R., & Laurent, B. C. (2005). Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair. Genes and Development, 19, 1656–1661.
    • (2005) Genes and Development , vol.19 , pp. 1656-1661
    • Chai, B.1    Huang, J.2    Cairns, B.R.3    Laurent, B.C.4
  • 79
    • 65549113750 scopus 로고    scopus 로고
    • CBP/p300-mediated acetylation of histone H3 on lysine 56
    • COI: 1:CAS:528:DC%2BD1MXivVKnsbc%3D, PID: 19270680
    • Das, C., Lucia, M. S., Hansen, K. C., & Tyler, J. K. (2009). CBP/p300-mediated acetylation of histone H3 on lysine 56. Nature, 459, 113–117.
    • (2009) Nature , vol.459 , pp. 113-117
    • Das, C.1    Lucia, M.S.2    Hansen, K.C.3    Tyler, J.K.4
  • 80
    • 22444448143 scopus 로고    scopus 로고
    • A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response
    • COI: 1:CAS:528:DC%2BD2MXmtVersr0%3D, PID: 16015338
    • Masumoto, H., Hawke, D., Kobayashi, R., & Verreault, A. (2005). A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response. Nature, 436, 294–298.
    • (2005) Nature , vol.436 , pp. 294-298
    • Masumoto, H.1    Hawke, D.2    Kobayashi, R.3    Verreault, A.4
  • 81
    • 78249276172 scopus 로고    scopus 로고
    • Hdac3 is essential for the maintenance of chromatin structure and genome stability
    • COI: 1:CAS:528:DC%2BC3cXhsValtLrM, PID: 21075309
    • Bhaskara, S., Knutson, S. K., Jiang, G., Chandrasekharan, M. B., Wilson, A. J., Zheng, S., et al. (2010). Hdac3 is essential for the maintenance of chromatin structure and genome stability. Cancer Cell, 18, 436–447.
    • (2010) Cancer Cell , vol.18 , pp. 436-447
    • Bhaskara, S.1    Knutson, S.K.2    Jiang, G.3    Chandrasekharan, M.B.4    Wilson, A.J.5    Zheng, S.6
  • 82
    • 84874399937 scopus 로고    scopus 로고
    • Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice
    • COI: 1:CAS:528:DC%2BC3sXjsFKmtL0%3D, PID: 23287868
    • Dovey, O. M., Foster, C. T., Conte, N., Edwards, S. A., Edwards, J. M., Singh, R., et al. (2013). Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice. Blood, 121, 1335–1344.
    • (2013) Blood , vol.121 , pp. 1335-1344
    • Dovey, O.M.1    Foster, C.T.2    Conte, N.3    Edwards, S.A.4    Edwards, J.M.5    Singh, R.6
  • 83
    • 77956341931 scopus 로고    scopus 로고
    • Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining
    • COI: 1:CAS:528:DC%2BC3cXhtVyiu73E, PID: 20802485
    • Miller, K. M., Tjeertes, J. V., Coates, J., Legube, G., Polo, S. E., Britton, S., et al. (2010). Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining. Nature Structural and Molecular Biology, 17, 1144–1151.
    • (2010) Nature Structural and Molecular Biology , vol.17 , pp. 1144-1151
    • Miller, K.M.1    Tjeertes, J.V.2    Coates, J.3    Legube, G.4    Polo, S.E.5    Britton, S.6
  • 84
    • 53149137486 scopus 로고    scopus 로고
    • Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
    • COI: 1:CAS:528:DC%2BD1cXht1GlsL3F, PID: 18835033
    • Wang, R. H., Sengupta, K., Li, C., Kim, H. S., Cao, L., Xiao, C., et al. (2008). Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell, 14, 312–323.
    • (2008) Cancer Cell , vol.14 , pp. 312-323
    • Wang, R.H.1    Sengupta, K.2    Li, C.3    Kim, H.S.4    Cao, L.5    Xiao, C.6
  • 85
    • 77951498720 scopus 로고    scopus 로고
    • A cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repair
    • COI: 1:CAS:528:DC%2BC3cXjtFSmur0%3D, PID: 20224553
    • Lee, H. S., Park, J. H., Kim, S. J., Kwon, S. J., & Kwon, J. (2010). A cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repair. EMBO Journal, 29, 1434–1445.
    • (2010) EMBO Journal , vol.29 , pp. 1434-1445
    • Lee, H.S.1    Park, J.H.2    Kim, S.J.3    Kwon, S.J.4    Kwon, J.5
  • 86
    • 0032252209 scopus 로고    scopus 로고
    • NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities
    • COI: 1:CAS:528:DyaK1MXjslahsg%3D%3D, PID: 9885572
    • Xue, Y., Wong, J., Moreno, G. T., Young, M. K., Cote, J., & Wang, W. (1998). NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities. Molecular Cell, 2, 851–861.
    • (1998) Molecular Cell , vol.2 , pp. 851-861
    • Xue, Y.1    Wong, J.2    Moreno, G.T.3    Young, M.K.4    Cote, J.5    Wang, W.6
  • 87
    • 0032538293 scopus 로고    scopus 로고
    • The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities
    • COI: 1:CAS:528:DyaK1cXntVSlsr0%3D, PID: 9790534
    • Zhang, Y., LeRoy, G., Seelig, H. P., Lane, W. S., & Reinberg, D. (1998). The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities. Cell, 95, 279–289.
    • (1998) Cell , vol.95 , pp. 279-289
    • Zhang, Y.1    LeRoy, G.2    Seelig, H.P.3    Lane, W.S.4    Reinberg, D.5
  • 88
    • 0032578762 scopus 로고    scopus 로고
    • Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex
    • COI: 1:CAS:528:DyaK1cXntlKjtbk%3D, PID: 9804427
    • Tong, J. K., Hassig, C. A., Schnitzler, G. R., Kingston, R. E., & Schreiber, S. L. (1998). Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex. Nature, 395, 917–921.
    • (1998) Nature , vol.395 , pp. 917-921
    • Tong, J.K.1    Hassig, C.A.2    Schnitzler, G.R.3    Kingston, R.E.4    Schreiber, S.L.5
  • 89
    • 0037453706 scopus 로고    scopus 로고
    • MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer
    • COI: 1:CAS:528:DC%2BD3sXjtlOqsL8%3D, PID: 12705869
    • Fujita, N., Jaye, D. L., Kajita, M., Geigerman, C., Moreno, C. S., & Wade, P. A. (2003). MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer. Cell, 113, 207–219.
    • (2003) Cell , vol.113 , pp. 207-219
    • Fujita, N.1    Jaye, D.L.2    Kajita, M.3    Geigerman, C.4    Moreno, C.S.5    Wade, P.A.6
  • 90
    • 77956870690 scopus 로고    scopus 로고
    • Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4. [Research Support, Non-U.S. Gov’t]
    • COI: 1:CAS:528:DC%2BC3cXpslOit7c%3D, PID: 20693977
    • Polo, S. E., Kaidi, A., Baskcomb, L., Galanty, Y., & Jackson, S. P. (2010). Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4. [Research Support, Non-U.S. Gov’t]. EMBO Journal, 29(18), 3130–3139. doi:10.1038/emboj.2010.188.
    • (2010) EMBO Journal , vol.29 , Issue.18 , pp. 3130-3139
    • Polo, S.E.1    Kaidi, A.2    Baskcomb, L.3    Galanty, Y.4    Jackson, S.P.5
  • 91
    • 79955130385 scopus 로고    scopus 로고
    • NuRD alert! NuRD regulates the DNA damage response
    • COI: 1:CAS:528:DC%2BC3MXkvF2gurc%3D, PID: 22122276
    • Smeenk, G., & van Attikum, H. (2011). NuRD alert! NuRD regulates the DNA damage response. Epigenomics, 3, 133–135.
    • (2011) Epigenomics , vol.3 , pp. 133-135
    • Smeenk, G.1    van Attikum, H.2
  • 92
    • 77956379478 scopus 로고    scopus 로고
    • The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage
    • COI: 1:CAS:528:DC%2BC3cXhtFyhu7fM, PID: 20805324
    • Larsen, D. H., Poinsignon, C., Gudjonsson, T., Dinant, C., Payne, M. R., Hari, F. J., et al. (2010). The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage. Journal of Cell Biology, 190, 731–740.
    • (2010) Journal of Cell Biology , vol.190 , pp. 731-740
    • Larsen, D.H.1    Poinsignon, C.2    Gudjonsson, T.3    Dinant, C.4    Payne, M.R.5    Hari, F.J.6
  • 93
    • 0033517797 scopus 로고    scopus 로고
    • Molecular association between ATR and two components of the nucleosome remodeling and deacetylating complex, HDAC2 and CHD4
    • COI: 1:CAS:528:DyaK1MXmsFaqurc%3D, PID: 10545197
    • Schmidt, D. R., & Schreiber, S. L. (1999). Molecular association between ATR and two components of the nucleosome remodeling and deacetylating complex, HDAC2 and CHD4. Biochemistry, 38, 14711–14717.
    • (1999) Biochemistry , vol.38 , pp. 14711-14717
    • Schmidt, D.R.1    Schreiber, S.L.2
  • 94
    • 33748054298 scopus 로고    scopus 로고
    • ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage
    • COI: 1:CAS:528:DC%2BD28XotlCgtLY%3D, PID: 16931761
    • Dornan, D., Shimizu, H., Mah, A., Dudhela, T., Eby, M., O’Rourke, K., et al. (2006). ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage. Science, 313, 1122–1126.
    • (2006) Science , vol.313 , pp. 1122-1126
    • Dornan, D.1    Shimizu, H.2    Mah, A.3    Dudhela, T.4    Eby, M.5    O’Rourke, K.6
  • 95
    • 0034594978 scopus 로고    scopus 로고
    • A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage
    • COI: 1:CAS:528:DC%2BD3cXhvVymu7w%3D, PID: 10716435
    • Tanaka, H., Arakawa, H., Yamaguchi, T., Shiraishi, K., Fukuda, S., Matsui, K., et al. (2000). A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage. Nature, 404, 42–49.
    • (2000) Nature , vol.404 , pp. 42-49
    • Tanaka, H.1    Arakawa, H.2    Yamaguchi, T.3    Shiraishi, K.4    Fukuda, S.5    Matsui, K.6
  • 96
    • 1642280957 scopus 로고    scopus 로고
    • UV-induced ataxia-telangiectasia-mutated and Rad3-related (ATR) activation requires replication stress
    • COI: 1:CAS:528:DC%2BD2cXhvFCht7g%3D, PID: 14742437
    • Ward, I. M., Minn, K., & Chen, J. (2004). UV-induced ataxia-telangiectasia-mutated and Rad3-related (ATR) activation requires replication stress. Journal of Biological Chemistry, 279, 9677–9680.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 9677-9680
    • Ward, I.M.1    Minn, K.2    Chen, J.3
  • 97
    • 17644432403 scopus 로고    scopus 로고
    • Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint
    • COI: 1:CAS:528:DC%2BD3cXksVGnt78%3D, PID: 10859164
    • Liu, Q., Guntuku, S., Cui, X. S., Matsuoka, S., Cortez, D., Tamai, K., et al. (2000). Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint. Genes and Development, 14, 1448–1459.
    • (2000) Genes and Development , vol.14 , pp. 1448-1459
    • Liu, Q.1    Guntuku, S.2    Cui, X.S.3    Matsuoka, S.4    Cortez, D.5    Tamai, K.6
  • 98
    • 0034312277 scopus 로고    scopus 로고
    • Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts
    • COI: 1:CAS:528:DC%2BD3cXotFOju7k%3D, PID: 11069891
    • Guo, Z., Kumagai, A., Wang, S. X., & Dunphy, W. G. (2000). Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts. Genes and Development, 14, 2745–2756.
    • (2000) Genes and Development , vol.14 , pp. 2745-2756
    • Guo, Z.1    Kumagai, A.2    Wang, S.X.3    Dunphy, W.G.4
  • 99
    • 0043032435 scopus 로고    scopus 로고
    • Human claspin is required for replication checkpoint control
    • COI: 1:CAS:528:DC%2BD3sXlvFOnt7g%3D, PID: 12766152
    • Chini, C. C., & Chen, J. (2003). Human claspin is required for replication checkpoint control. Journal of Biological Chemistry, 278, 30057–30062.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 30057-30062
    • Chini, C.C.1    Chen, J.2
  • 100
    • 33745639254 scopus 로고    scopus 로고
    • Identification of conserved pathways of DNA-damage response and radiation protection by genome-wide RNAi
    • PID: 16824923
    • van Haaften, G., Romeijn, R., Pothof, J., Koole, W., Mullenders, L. H., Pastink, A., et al. (2006). Identification of conserved pathways of DNA-damage response and radiation protection by genome-wide RNAi. Current Biology, 16, 1344–1350.
    • (2006) Current Biology , vol.16 , pp. 1344-1350
    • van Haaften, G.1    Romeijn, R.2    Pothof, J.3    Koole, W.4    Mullenders, L.H.5    Pastink, A.6
  • 101
    • 84903789589 scopus 로고    scopus 로고
    • Mta2 promotes Tipin-dependent maintenance of replication fork integrity
    • COI: 1:CAS:528:DC%2BC2cXhsFantb3L, PID: 24830473
    • Errico, A., Aze, A., & Costanzo, V. (2014). Mta2 promotes Tipin-dependent maintenance of replication fork integrity. Cell Cycle, 13, 2120–2128.
    • (2014) Cell Cycle , vol.13 , pp. 2120-2128
    • Errico, A.1    Aze, A.2    Costanzo, V.3
  • 102
    • 80053984327 scopus 로고    scopus 로고
    • Activation of Hif1alpha by the prolylhydroxylase inhibitor dimethyoxalyglycine decreases radiosensitivity
    • COI: 1:CAS:528:DC%2BC3MXhtl2mt7bP, PID: 22016813
    • Ayrapetov, M. K., Xu, C., Sun, Y., Zhu, K., Parmar, K., D’Andrea, A. D., et al. (2011). Activation of Hif1alpha by the prolylhydroxylase inhibitor dimethyoxalyglycine decreases radiosensitivity. PLoS One, 6, e26064.
    • (2011) PLoS One , vol.6 , pp. e26064
    • Ayrapetov, M.K.1    Xu, C.2    Sun, Y.3    Zhu, K.4    Parmar, K.5    D’Andrea, A.D.6
  • 103
    • 84885663744 scopus 로고    scopus 로고
    • Histone deacetylase regulation of ATM-mediated DNA damage signaling
    • COI: 1:CAS:528:DC%2BC3sXhsFOhurvN, PID: 23939379
    • Thurn, K. T., Thomas, S., Raha, P., Qureshi, I., & Munster, P. N. (2013). Histone deacetylase regulation of ATM-mediated DNA damage signaling. Molecular Cancer Therapeutics, 12, 2078–2087.
    • (2013) Molecular Cancer Therapeutics , vol.12 , pp. 2078-2087
    • Thurn, K.T.1    Thomas, S.2    Raha, P.3    Qureshi, I.4    Munster, P.N.5
  • 105
    • 84878269070 scopus 로고    scopus 로고
    • CHD4 in the DNA-damage response and cell cycle progression: not so NuRDy now
    • PID: 23697937
    • O’Shaughnessy, A., & Hendrich, B. (2013). CHD4 in the DNA-damage response and cell cycle progression: not so NuRDy now. Biochemical Society Transactions, 41, 777–782.
    • (2013) Biochemical Society Transactions , vol.41 , pp. 777-782
    • O’Shaughnessy, A.1    Hendrich, B.2
  • 106
    • 84863166648 scopus 로고    scopus 로고
    • Chromodomain helicase DNA-binding protein 4 (CHD4) regulates homologous recombination DNA repair, and its deficiency sensitizes cells to poly(ADP-ribose) polymerase (PARP) inhibitor treatment
    • COI: 1:CAS:528:DC%2BC38Xisl2ksrg%3D, PID: 22219182
    • Pan, M. R., Hsieh, H. J., Dai, H., Hung, W. C., Li, K., Peng, G., et al. (2012). Chromodomain helicase DNA-binding protein 4 (CHD4) regulates homologous recombination DNA repair, and its deficiency sensitizes cells to poly(ADP-ribose) polymerase (PARP) inhibitor treatment. Journal of Biological Chemistry, 287, 6764–6772.
    • (2012) Journal of Biological Chemistry , vol.287 , pp. 6764-6772
    • Pan, M.R.1    Hsieh, H.J.2    Dai, H.3    Hung, W.C.4    Li, K.5    Peng, G.6
  • 107
    • 84861895067 scopus 로고    scopus 로고
    • A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure
    • COI: 1:CAS:528:DC%2BC38XmtVCis7Y%3D, PID: 22531782
    • Luijsterburg, M. S., Acs, K., Ackermann, L., Wiegant, W. W., Bekker-Jensen, S., Larsen, D. H., et al. (2012). A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure. EMBO Journal, 31, 2511–2527.
    • (2012) EMBO Journal , vol.31 , pp. 2511-2527
    • Luijsterburg, M.S.1    Acs, K.2    Ackermann, L.3    Wiegant, W.W.4    Bekker-Jensen, S.5    Larsen, D.H.6
  • 108
    • 80052209365 scopus 로고    scopus 로고
    • Mi-2/NuRD complex function is required for normal S phase progression and assembly of pericentric heterochromatin
    • COI: 1:CAS:528:DC%2BC3MXht1SisL3M, PID: 21737684
    • Sims, J. K., & Wade, P. A. (2011). Mi-2/NuRD complex function is required for normal S phase progression and assembly of pericentric heterochromatin. Molecular Biology of the Cell, 22, 3094–3102.
    • (2011) Molecular Biology of the Cell , vol.22 , pp. 3094-3102
    • Sims, J.K.1    Wade, P.A.2
  • 110
    • 84873420524 scopus 로고    scopus 로고
    • The MTA family proteins as novel histone H3 binding proteins
    • PID: 23286669
    • Wu, M., Wang, L., Li, Q., Li, J., Qin, J., & Wong, J. (2013). The MTA family proteins as novel histone H3 binding proteins. Cell Bioscience, 3, 1.
    • (2013) Cell Bioscience , vol.3 , pp. 1
    • Wu, M.1    Wang, L.2    Li, Q.3    Li, J.4    Qin, J.5    Wong, J.6
  • 111
    • 47349107760 scopus 로고    scopus 로고
    • ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
    • COI: 1:CAS:528:DC%2BD1cXpsFOgt7c%3D, PID: 18657500
    • Goodarzi, A. A., Noon, A. T., Deckbar, D., Ziv, Y., Shiloh, Y., Lobrich, M., et al. (2008). ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Molecular Cell, 31, 167–177.
    • (2008) Molecular Cell , vol.31 , pp. 167-177
    • Goodarzi, A.A.1    Noon, A.T.2    Deckbar, D.3    Ziv, Y.4    Shiloh, Y.5    Lobrich, M.6
  • 112
    • 0242552447 scopus 로고    scopus 로고
    • Emerging roles of MTA family members in human cancers
    • COI: 1:CAS:528:DC%2BD3sXhtVSjtrrO
    • Kumar, R., Wang, R. A., & Bagheri-Yarmand, R. (2003). Emerging roles of MTA family members in human cancers. Seminar in Oncology, 30, 30–37.
    • (2003) Seminar in Oncology , vol.30 , pp. 30-37
    • Kumar, R.1    Wang, R.A.2    Bagheri-Yarmand, R.3
  • 113
    • 84881476164 scopus 로고    scopus 로고
    • Repression of NR4A1 by a chromatin modifier promotes docetaxel resistance in PC-3 human prostate cancer cells
    • COI: 1:CAS:528:DC%2BC3sXhtVyqt77J, PID: 23831020
    • Yu, L., Su, Y. S., Zhao, J., Wang, H., & Li, W. (2013). Repression of NR4A1 by a chromatin modifier promotes docetaxel resistance in PC-3 human prostate cancer cells. FEBS Letters, 587, 2542–2551.
    • (2013) FEBS Letters , vol.587 , pp. 2542-2551
    • Yu, L.1    Su, Y.S.2    Zhao, J.3    Wang, H.4    Li, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.