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Volumn 40, Issue 5, 2014, Pages 1003-1021

Quantification of liver iron with MRI: State of the art and remaining challenges

Author keywords

Liver iron; MR relaxometry; R2; R2 ; Susceptometry

Indexed keywords

DEFERASIROX; DEFERIPRONE; DEFEROXAMINE; FERRITIN; IRON; TRANSFERRIN;

EID: 84913607974     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.24584     Document Type: Article
Times cited : (223)

References (140)
  • 4
    • 0042866137 scopus 로고    scopus 로고
    • Physiology and molecular biology of dietary iron absorption
    • Miret S, Simpson RJ, McKie AT. Physiology and molecular biology of dietary iron absorption. Annu Rev Nutr 2003;23:283-301.
    • (2003) Annu Rev Nutr , vol.23 , pp. 283-301
    • Miret, S.1    Simpson, R.J.2    McKie, A.T.3
  • 5
    • 2542560427 scopus 로고    scopus 로고
    • Hereditary hemochromatosis-A new look at an old disease
    • Pietrangelo A. Hereditary hemochromatosis-a new look at an old disease. N Engl J Med 2004;350:2383-2397.
    • (2004) N Engl J Med , vol.350 , pp. 2383-2397
    • Pietrangelo, A.1
  • 6
    • 0037217987 scopus 로고    scopus 로고
    • Noninvasive measurement of iron: Report of an NIDDK workshop
    • Brittenham GM, Badman DG. Noninvasive measurement of iron: report of an NIDDK workshop. Blood 2003;101:15-19.
    • (2003) Blood , vol.101 , pp. 15-19
    • Brittenham, G.M.1    Badman, D.G.2
  • 7
    • 0029919699 scopus 로고    scopus 로고
    • Abdominal iron deposition: Metabolism, MR findings, and clinical importance
    • Siegelman ES, Mitchell DG, Semelka RC. Abdominal iron deposition: metabolism, MR findings, and clinical importance. Radiology 1996;199:13-22.
    • (1996) Radiology , vol.199 , pp. 13-22
    • Siegelman, E.S.1    Mitchell, D.G.2    Semelka, R.C.3
  • 8
    • 9244261562 scopus 로고    scopus 로고
    • Relaxation induced by ferritin: A better understanding for an improved MRI iron quantification
    • Gossuin Y, Muller RN, Gillis P. Relaxation induced by ferritin: a better understanding for an improved MRI iron quantification. NMR Biomed 2004;17:427-432.
    • (2004) NMR Biomed , vol.17 , pp. 427-432
    • Gossuin, Y.1    Muller, R.N.2    Gillis, P.3
  • 9
    • 78649306862 scopus 로고    scopus 로고
    • Magnetic resonance imaging quantification of liver iron
    • ix
    • Sirlin CB, Reeder SB. Magnetic resonance imaging quantification of liver iron. Magn Reson Imaging Clin N Am 2010;18:359-381, ix.
    • (2010) Magn Reson Imaging Clin N Am , vol.18 , pp. 359-381
    • Sirlin, C.B.1    Reeder, S.B.2
  • 10
    • 0016715330 scopus 로고
    • Difference between the two ironbinding sites of transferrin
    • Princiotto JV, Zapolski EJ. Difference between the two ironbinding sites of transferrin. Nature 1975;255:87-88.
    • (1975) Nature , vol.255 , pp. 87-88
    • Princiotto, J.V.1    Zapolski, E.J.2
  • 11
    • 34248337416 scopus 로고    scopus 로고
    • Iron overload syndromes and the liver
    • Batts KP. Iron overload syndromes and the liver. Mod Pathol 2007;20(Suppl 1):31-39.
    • (2007) Mod Pathol , vol.20 , pp. 31-39
    • Batts, K.P.1
  • 12
    • 9244220587 scopus 로고    scopus 로고
    • Single spin-echo proton transverse relaxometry of iron-loaded liver
    • St Pierre TG, Clark PR, Chua-Anusorn W. Single spin-echo proton transverse relaxometry of iron-loaded liver. NMR Biomed 2004;17:446-458.
    • (2004) NMR Biomed , vol.17 , pp. 446-458
    • St Pierre, T.G.1    Clark, P.R.2    Chua-Anusorn, W.3
  • 13
    • 77955508573 scopus 로고    scopus 로고
    • Hereditary hemochromatosis: Pathogenesis, diagnosis, and treatment
    • e391-392
    • Pietrangelo A. Hereditary hemochromatosis: pathogenesis, diagnosis, and treatment. Gastroenterology 2010;139:393-408, e391-392.
    • (2010) Gastroenterology , vol.139 , pp. 393-408
    • Pietrangelo, A.1
  • 14
    • 11244355277 scopus 로고    scopus 로고
    • Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance
    • St Pierre TG, Clark PR, Chua-anusorn W, et al. Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance. Blood 2005;105:855-861.
    • (2005) Blood , vol.105 , pp. 855-861
    • St Pierre, T.G.1    Clark, P.R.2    Chua-Anusorn, W.3
  • 16
    • 33646407268 scopus 로고    scopus 로고
    • Cardiac morbidity and mortality in deferoxamine- or deferiprone-treated patients with thalassemia major
    • Borgna-Pignatti C, Cappellini MD, De Stefano P, et al. Cardiac morbidity and mortality in deferoxamine- or deferiprone-treated patients with thalassemia major. Blood 2006;107:3733-3737.
    • (2006) Blood , vol.107 , pp. 3733-3737
    • Borgna-Pignatti, C.1    Cappellini, M.D.2    De, S.P.3
  • 17
    • 57049104663 scopus 로고    scopus 로고
    • Cardiac iron across different transfusion-dependent diseases
    • Wood JC. Cardiac iron across different transfusion-dependent diseases. Blood Rev 2008;22(Suppl 2):14-21.
    • (2008) Blood Rev , vol.22 , pp. 14-21
    • Wood, J.C.1
  • 18
    • 0033848697 scopus 로고    scopus 로고
    • EASL international consensus conference on haemochromatosis
    • Adams P, Brissot P, Powell LW. EASL International Consensus Conference on Haemochromatosis. J Hepatol 2000;33:485-504.
    • (2000) J Hepatol , vol.33 , pp. 485-504
    • Adams, P.1    Brissot, P.2    Powell, L.W.3
  • 20
    • 0034056296 scopus 로고    scopus 로고
    • Iron deposition and progression of disease in chronic hepatitis C. Role of interface hepatitis, portal inflammation, and HFE missense mutations
    • Pirisi M, Scott CA, Avellini C, et al. Iron deposition and progression of disease in chronic hepatitis C. Role of interface hepatitis, portal inflammation, and HFE missense mutations. Am J Clin Pathol 2000;113:546-554.
    • (2000) Am J Clin Pathol , vol.113 , pp. 546-554
    • Pirisi, M.1    Scott, C.A.2    Avellini, C.3
  • 21
    • 79959547265 scopus 로고    scopus 로고
    • Diagnosis and management of hemochromatosis: 2011 practice guideline by the American Association for the Study of Liver Diseases
    • Bacon BR, Adams PC, Kowdley KV, Powell LW, Tavill AS. Diagnosis and management of hemochromatosis: 2011 practice guideline by the American Association for the Study of Liver Diseases. Hepatology 2011;54:328-343.
    • (2011) Hepatology , vol.54 , pp. 328-343
    • Bacon, B.R.1    Adams, P.C.2    Kowdley, K.V.3    Powell, L.W.4    Tavill, A.S.5
  • 22
    • 0041382552 scopus 로고    scopus 로고
    • Iron as a co-morbid factor in nonhemochromatotic liver disease
    • Bonkovsky HL, Lambrecht RW, Shan Y. Iron as a co-morbid factor in nonhemochromatotic liver disease. Alcohol 2003;30:137-144.
    • (2003) Alcohol , vol.30 , pp. 137-144
    • Bonkovsky, H.L.1    Lambrecht, R.W.2    Shan, Y.3
  • 24
  • 25
    • 79955431601 scopus 로고    scopus 로고
    • Group H-CT Iron levels in hepatocytes and portal tract cells predict progression and outcomes of patients with advanced chronic hepatitis C
    • e1493
    • Lambrecht RW, Sterling RK, Naishadham D, et al., Group H-CT. Iron levels in hepatocytes and portal tract cells predict progression and outcomes of patients with advanced chronic hepatitis C. Gastroenterology 2011;140:1490-1500 e1493.
    • (2011) Gastroenterology , vol.140 , pp. 1490-1500
    • Lambrecht, R.W.1    Sterling, R.K.2    Naishadham, D.3
  • 27
  • 28
    • 0035725868 scopus 로고    scopus 로고
    • Practical management of iron overload
    • Porter JB. Practical management of iron overload. Br J Haematol 2001;115:239-252.
    • (2001) Br J Haematol , vol.115 , pp. 239-252
    • Porter, J.B.1
  • 29
    • 48949084181 scopus 로고    scopus 로고
    • Oral iron chelators and the treatment of iron overload in pediatric patients with chronic anemia
    • Vichinsky E. Oral iron chelators and the treatment of iron overload in pediatric patients with chronic anemia. Pediatrics 2008; 121:1253-1256.
    • (2008) Pediatrics , vol.121 , pp. 1253-1256
    • Vichinsky, E.1
  • 31
    • 0022656390 scopus 로고
    • Value of hepatic iron measurements in early hemochromatosis and determination of the critical iron level associated with fibrosis
    • Bassett ML, Halliday JW, Powell LW. Value of hepatic iron measurements in early hemochromatosis and determination of the critical iron level associated with fibrosis. Hepatology 1986;6:24- 29.
    • (1986) Hepatology , vol.6 , pp. 24-29
    • Bassett, M.L.1    Halliday, J.W.2    Powell, L.W.3
  • 32
    • 0034601375 scopus 로고    scopus 로고
    • Hepatic iron concentration and total body iron stores in thalassemia major
    • Angelucci E, Brittenham GM, McLaren CE, et al. Hepatic iron concentration and total body iron stores in thalassemia major. N Engl J Med 2000;343:327-331.
    • (2000) N Engl J Med , vol.343 , pp. 327-331
    • Angelucci, E.1    Brittenham, G.M.2    McLaren, C.E.3
  • 33
    • 78649903132 scopus 로고    scopus 로고
    • Controversies surrounding iron chelation therapy for MDS
    • Leitch HA. Controversies surrounding iron chelation therapy for MDS. Blood Rev 2011;25:17-31.
    • (2011) Blood Rev , vol.25 , pp. 17-31
    • Leitch, H.A.1
  • 34
    • 23744459788 scopus 로고    scopus 로고
    • MRI R2 and R2∗ mapping accurately estimates hepatic iron concentration in transfusiondependent thalassemia and sickle cell disease patients
    • Wood JC, Enriquez C, Ghugre N, et al. MRI R2 and R2∗ mapping accurately estimates hepatic iron concentration in transfusiondependent thalassemia and sickle cell disease patients. Blood 2005;106:1460-1465.
    • (2005) Blood , vol.106 , pp. 1460-1465
    • Wood, J.C.1    Enriquez, C.2    Ghugre, N.3
  • 35
    • 0017650343 scopus 로고
    • Familial hemochromatosis: Characteristics of the precirrhotic stage in a large kindred
    • Baltimore
    • Rowe JW, Wands JR, Mezey E, et al. Familial hemochromatosis: characteristics of the precirrhotic stage in a large kindred. Medicine (Baltimore) 1977;56:197-211.
    • (1977) Medicine , vol.56 , pp. 197-211
    • Rowe, J.W.1    Wands, J.R.2    Mezey, E.3
  • 39
    • 2442473448 scopus 로고    scopus 로고
    • Ultrasound-guided percutaneous liver biopsy: Indications, risks, and technique
    • Copel L, Sosna J, Kruskal JB, Kane RA. Ultrasound-guided percutaneous liver biopsy: indications, risks, and technique. Surg Technol Int 2003;11:154-160.
    • (2003) Surg Technol Int , vol.11 , pp. 154-160
    • Copel, L.1    Sosna, J.2    Kruskal, J.B.3    Kane, R.A.4
  • 40
    • 0033505032 scopus 로고    scopus 로고
    • Quantification of liver iron overload by T2 quantitative magnetic resonance imaging in thalassemia: Impact of chronic hepatitis C on measurements
    • Papakonstantinou O, Kostaridou S, Maris T, et al. Quantification of liver iron overload by T2 quantitative magnetic resonance imaging in thalassemia: impact of chronic hepatitis C on measurements. J Pediatr Hematol Oncol 1999;21:142-148.
    • (1999) J Pediatr Hematol Oncol , vol.21 , pp. 142-148
    • Papakonstantinou, O.1    Kostaridou, S.2    Maris, T.3
  • 41
    • 0034235835 scopus 로고    scopus 로고
    • Severity of iron overload in patients with sickle cell disease receiving chronic red blood cell transfusion therapy
    • Harmatz P, Butensky E, Quirolo K, et al. Severity of iron overload in patients with sickle cell disease receiving chronic red blood cell transfusion therapy. Blood 2000;96:76-79.
    • (2000) Blood , vol.96 , pp. 76-79
    • Harmatz, P.1    Butensky, E.2    Quirolo, K.3
  • 42
    • 36849004367 scopus 로고    scopus 로고
    • Liver biopsy results in patients with sickle cell disease on chronic transfusions: Poor correlation with ferritin levels
    • Karam LB, Disco D, Jackson SM, et al. Liver biopsy results in patients with sickle cell disease on chronic transfusions: poor correlation with ferritin levels. Pediatr Blood Cancer 2008;50: 62-65.
    • (2008) Pediatr Blood Cancer , vol.50 , pp. 62-65
    • Karam, L.B.1    Disco, D.2    Jackson, S.M.3
  • 43
    • 73949153192 scopus 로고    scopus 로고
    • Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury
    • Adamkiewicz TV, Abboud MR, Paley C, et al. Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury. Blood 2009;114:4632-4638.
    • (2009) Blood , vol.114 , pp. 4632-4638
    • Adamkiewicz, T.V.1    Abboud, M.R.2    Paley, C.3
  • 44
    • 0035132419 scopus 로고    scopus 로고
    • Noninvasive methods for quantitative assessment of transfusional iron overload in sickle cell disease
    • Brittenham GM, Sheth S, Allen CJ, Farrell DE. Noninvasive methods for quantitative assessment of transfusional iron overload in sickle cell disease. Semin Hematol 2001;38:37-56.
    • (2001) Semin Hematol , vol.38 , pp. 37-56
    • Brittenham, G.M.1    Sheth, S.2    Allen, C.J.3    Farrell, D.E.4
  • 45
    • 0030013529 scopus 로고    scopus 로고
    • The role of magnetic susceptibility in magnetic resonance imaging: MRI magnetic compatibility of the first and second kinds
    • Schenck JF. The role of magnetic susceptibility in magnetic resonance imaging: MRI magnetic compatibility of the first and second kinds. Med Phys 1996;23:815-850.
    • (1996) Med Phys , vol.23 , pp. 815-850
    • Schenck, J.F.1
  • 46
    • 0020465049 scopus 로고
    • Magnetic-susceptibility measurement of human iron stores
    • Brittenham GM, Farrell DE, Harris JW, et al. Magnetic-susceptibility measurement of human iron stores. N Engl J Med 1982; 307:1671-1675.
    • (1982) N Engl J Med , vol.307 , pp. 1671-1675
    • Brittenham, G.M.1    Farrell, D.E.2    Harris, J.W.3
  • 47
    • 34047197935 scopus 로고    scopus 로고
    • Noninvasive liver-iron measurements with a room-temperature susceptometer
    • Avrin WF, Kumar S. Noninvasive liver-iron measurements with a room-temperature susceptometer. Physiol Meas 2007;28:349- 361.
    • (2007) Physiol Meas , vol.28 , pp. 349-361
    • Avrin, W.F.1    Kumar, S.2
  • 48
    • 0842283228 scopus 로고    scopus 로고
    • Non-invasive assessment of hepatic iron stores by MRI
    • Gandon Y, Olivie D, Guyader D, et al. Non-invasive assessment of hepatic iron stores by MRI. Lancet 2004;363:357-362.
    • (2004) Lancet , vol.363 , pp. 357-362
    • Gandon, Y.1    Olivie, D.2    Guyader, D.3
  • 50
    • 0034971950 scopus 로고    scopus 로고
    • Imaging of diffuse liver disease
    • Mortele KJ, Ros PR. Imaging of diffuse liver disease. Semin Liver Dis 2001;21:195-212.
    • (2001) Semin Liver Dis , vol.21 , pp. 195-212
    • Mortele, K.J.1    Ros, P.R.2
  • 51
    • 80052688847 scopus 로고    scopus 로고
    • Quantification of liver iron content with CT-added value of dual-energy
    • Fischer MA, Reiner CS, Raptis D, et al. Quantification of liver iron content with CT-added value of dual-energy. Eur Radiol 2011;21:1727-1732.
    • (2011) Eur Radiol , vol.21 , pp. 1727-1732
    • Fischer, M.A.1    Reiner, C.S.2    Raptis, D.3
  • 52
    • 77449127465 scopus 로고    scopus 로고
    • Diffuse liver disease: Strategies for hepatic CT and MR imaging
    • Boll DT, Merkle EM. Diffuse liver disease: strategies for hepatic CT and MR imaging. Radiographics 2009;29:1591-1614.
    • (2009) Radiographics , vol.29 , pp. 1591-1614
    • Boll, D.T.1    Merkle, E.M.2
  • 53
    • 0021958402 scopus 로고
    • Increased hepatic density and phospholipidosis due to amiodarone
    • Goldman IS, Winkler ML, Raper SE, et al. Increased hepatic density and phospholipidosis due to amiodarone. AJR Am J Roentgenol 1985;144:541-546.
    • (1985) AJR Am J Roentgenol , vol.144 , pp. 541-546
    • Goldman, I.S.1    Winkler, M.L.2    Raper, S.E.3
  • 55
    • 33845959522 scopus 로고    scopus 로고
    • Liver imaging findings of Wilson's disease
    • Akpinar E, Akhan O. Liver imaging findings of Wilson's disease. Eur J Radiol 2007;61:25-32.
    • (2007) Eur J Radiol , vol.61 , pp. 25-32
    • Akpinar, E.1    Akhan, O.2
  • 56
    • 79951838524 scopus 로고    scopus 로고
    • Relaxivity-iron calibration in hepatic iron overload: Probing underlying biophysical mechanisms using a Monte Carlo model
    • Ghugre NR, Wood JC. Relaxivity-iron calibration in hepatic iron overload: probing underlying biophysical mechanisms using a Monte Carlo model. Magn Reson Med 2011;65:837-847.
    • (2011) Magn Reson Med , vol.65 , pp. 837-847
    • Ghugre, N.R.1    Wood, J.C.2
  • 57
    • 0036264295 scopus 로고    scopus 로고
    • Theory of nonexponential NMR signal decay in liver with iron overload or superparamagnetic iron oxide particles
    • Jensen JH, Chandra R. Theory of nonexponential NMR signal decay in liver with iron overload or superparamagnetic iron oxide particles. Magn Reson Med 2002;47:1131-1138.
    • (2002) Magn Reson Med , vol.47 , pp. 1131-1138
    • Jensen, J.H.1    Chandra, R.2
  • 58
    • 0034744087 scopus 로고    scopus 로고
    • On T2-shortening by weakly magnetized particles: The chemical exchange model
    • Brooks RA, Moiny F, Gillis P. On T2-shortening by weakly magnetized particles: the chemical exchange model. Magn Reson Med 2001;45:1014-1020.
    • (2001) Magn Reson Med , vol.45 , pp. 1014-1020
    • Brooks, R.A.1    Moiny, F.2    Gillis, P.3
  • 59
    • 0036893012 scopus 로고    scopus 로고
    • Anomalous nuclear magnetic relaxation of aqueous solutions of ferritin: An unprecedented first-order mechanism
    • Gossuin Y, Roch A, Muller RN, Gillis P, Lo Bue, F. Anomalous nuclear magnetic relaxation of aqueous solutions of ferritin: an unprecedented first-order mechanism. Magn Reson Med 2002; 48:959-964.
    • (2002) Magn Reson Med , vol.48 , pp. 959-964
    • Gossuin, Y.1    Roch, A.2    Muller, R.N.3    Gillis, P.4    Lo Bue, F.5
  • 60
    • 0027945442 scopus 로고
    • Hemochromatosis: Diagnosis and quantification of liver iron with gradient-echo MR imaging
    • Gandon Y, Guyader D, Heautot JF, et al. Hemochromatosis: diagnosis and quantification of liver iron with gradient-echo MR imaging. Radiology 1994;193:533-538.
    • (1994) Radiology , vol.193 , pp. 533-538
    • Gandon, Y.1    Guyader, D.2    Heautot, J.F.3
  • 63
    • 84859800294 scopus 로고    scopus 로고
    • Standardization of the quantification of iron concentration in the liver by magnetic resonance imaging
    • Alustiza JM, Emparanza JI, Aldazabal P, et al. [Standardization of the quantification of iron concentration in the liver by magnetic resonance imaging]. Radiologia 2012;54:149-154.
    • (2012) Radiologia , vol.54 , pp. 149-154
    • Alustiza, J.M.1    Emparanza, J.I.2    Aldazabal, P.3
  • 64
    • 51649122677 scopus 로고    scopus 로고
    • Quantitative liver iron measurement by magnetic resonance imaging: In vitro and in vivo assessment of the liver to muscle signal intensity and the R2∗ methods
    • Virtanen JM, Komu ME, Parkkola RK. Quantitative liver iron measurement by magnetic resonance imaging: in vitro and in vivo assessment of the liver to muscle signal intensity and the R2∗ methods. Magn Reson Imaging 2008;26:1175-1182.
    • (2008) Magn Reson Imaging , vol.26 , pp. 1175-1182
    • Virtanen, J.M.1    Komu, M.E.2    Parkkola, R.K.3
  • 65
    • 33745727596 scopus 로고    scopus 로고
    • Liver iron content assessment by routine and simple magnetic resonance imaging procedure in highly transfused patients
    • Rose C, Vandevenne P, Bourgeois E, Cambier N, Ernst O. Liver iron content assessment by routine and simple magnetic resonance imaging procedure in highly transfused patients. Eur J Haematol 2006;77:145-149.
    • (2006) Eur J Haematol , vol.77 , pp. 145-149
    • Rose, C.1    Vandevenne, P.2    Bourgeois, E.3    Cambier, N.4    Ernst, O.5
  • 66
    • 84864017879 scopus 로고    scopus 로고
    • Use of fat suppression in R(2) relaxometry with MRI for the quantification of tissue iron overload in beta-thalassemic patients
    • Papakonstantinou O, Foufa K, Benekos O, et al. Use of fat suppression in R(2) relaxometry with MRI for the quantification of tissue iron overload in beta-thalassemic patients. Magn Reson Imaging 2012;30:926-933.
    • (2012) Magn Reson Imaging , vol.30 , pp. 926-933
    • Papakonstantinou, O.1    Foufa, K.2    Benekos, O.3
  • 67
    • 39349091613 scopus 로고    scopus 로고
    • Magnetic resonance imaging assessment of excess iron in thalassemia, sickle cell disease and other iron overload diseases
    • Wood JC, Ghugre N. Magnetic resonance imaging assessment of excess iron in thalassemia, sickle cell disease and other iron overload diseases. Hemoglobin 2008;32:85-96.
    • (2008) Hemoglobin , vol.32 , pp. 85-96
    • Wood, J.C.1    Ghugre, N.2
  • 68
    • 0030911943 scopus 로고    scopus 로고
    • Hepatic hemosiderosis in non-human primates: Quantification of liver iron using different field strengths
    • Bulte JW, Miller GF, Vymazal J, Brooks RA, Frank JA. Hepatic hemosiderosis in non-human primates: quantification of liver iron using different field strengths. Magn Reson Med 1997;37: 530-536.
    • (1997) Magn Reson Med , vol.37 , pp. 530-536
    • Bulte, J.W.1    Miller, G.F.2    Vymazal, J.3    Brooks, R.A.4    Frank, J.A.5
  • 69
    • 0042808828 scopus 로고    scopus 로고
    • Bi-exponential proton transverse relaxation rate (R2) image analysis using RF field intensity-weighted spin density projection: Potential for R2 measurement of iron-loaded liver
    • Clark PR, Chua-anusorn W, St Pierre TG. Bi-exponential proton transverse relaxation rate (R2) image analysis using RF field intensity-weighted spin density projection: potential for R2 measurement of iron-loaded liver. Magn Reson Imaging 2003;21: 519-530.
    • (2003) Magn Reson Imaging , vol.21 , pp. 519-530
    • Clark, P.R.1    Chua-Anusorn, W.2    St Pierre, T.G.3
  • 70
    • 33747888911 scopus 로고    scopus 로고
    • Advances in white matter imaging: A review of in vivo magnetic resonance methodologies and their applicability to the study of development and aging
    • Wozniak JR, Lim KO. Advances in white matter imaging: a review of in vivo magnetic resonance methodologies and their applicability to the study of development and aging. Neurosci Biobehav Rev 2006;30:762-774.
    • (2006) Neurosci Biobehav Rev , vol.30 , pp. 762-774
    • Wozniak, J.R.1    Lim, K.O.2
  • 72
    • 0025230594 scopus 로고
    • Non-invasive quantitation of liver iron-overload by magnetic resonance imaging
    • Kaltwasser JP, Gottschalk R, Schalk KP, Hartl W. Non-invasive quantitation of liver iron-overload by magnetic resonance imaging. Br J Haematol 1990;74:360-363.
    • (1990) Br J Haematol , vol.74 , pp. 360-363
    • Kaltwasser, J.P.1    Gottschalk, R.2    Schalk, K.P.3    Hartl, W.4
  • 73
    • 0028278974 scopus 로고
    • Assessment of hepatic iron overload in thalassemic patients by magnetic resonance spectroscopy
    • Dixon RM, Styles P, al-Refaie FN, et al. Assessment of hepatic iron overload in thalassemic patients by magnetic resonance spectroscopy. Hepatology 1994;19:904-910.
    • (1994) Hepatology , vol.19 , pp. 904-910
    • Dixon, R.M.1    Styles, P.2    Al-Refaie, F.N.3
  • 74
    • 0036199279 scopus 로고    scopus 로고
    • Evaluation of iron overload by single voxel MRS measurement of liver T2
    • Wang ZJ, Haselgrove JC, Martin MB, et al. Evaluation of iron overload by single voxel MRS measurement of liver T2. J Magn Reson Imaging 2002;15:395-400.
    • (2002) J Magn Reson Imaging , vol.15 , pp. 395-400
    • Wang, Z.J.1    Haselgrove, J.C.2    Martin, M.B.3
  • 75
    • 79954605536 scopus 로고    scopus 로고
    • The effect of reducing repetition time TR on the measurement of liver R2 for the purpose of measuring liver iron concentration
    • Pavitt HL, Aydinok Y, El-Beshlawy A, et al. The effect of reducing repetition time TR on the measurement of liver R2 for the purpose of measuring liver iron concentration. Magn Reson Med 2011;65:1346-1351.
    • (2011) Magn Reson Med , vol.65 , pp. 1346-1351
    • Pavitt, H.L.1    Aydinok, Y.2    El-Beshlawy, A.3
  • 76
    • 84913618782 scopus 로고    scopus 로고
    • Multicenter validation of spin-density projection-assisted R2-MRI for the noninvasive measurement of liver iron concentration
    • Epub ahead of print
    • St-Pierre TG, El-Beshlawy A, Elalfy M, et al. Multicenter validation of spin-density projection-assisted R2-MRI for the noninvasive measurement of liver iron concentration. J Magn Reson Imaging [Epub ahead of print].
    • J Magn Reson Imaging
    • St-Pierre, T.G.1    El-Beshlawy, A.2    Elalfy, M.3
  • 77
    • 67650091408 scopus 로고    scopus 로고
    • Effect of Press and STEAM sequences on magnetic resonance spectroscopic liver fat quantification
    • Hamilton G, Middleton MS, Bydder M, et al. Effect of PRESS and STEAM sequences on magnetic resonance spectroscopic liver fat quantification. J Magn Reson Imaging 2009;30:145- 152.
    • (2009) J Magn Reson Imaging , vol.30 , pp. 145-152
    • Hamilton, G.1    Middleton, M.S.2    Bydder, M.3
  • 78
    • 80051586308 scopus 로고    scopus 로고
    • In vivo characterization of the liver fat (1)H MR spectrum
    • Hamilton G, Yokoo T, Bydder M, et al. In vivo characterization of the liver fat (1)H MR spectrum. NMR Biomed 2011;24:784-790.
    • (2011) NMR Biomed , vol.24 , pp. 784-790
    • Hamilton, G.1    Yokoo, T.2    Bydder, M.3
  • 79
    • 84913609987 scopus 로고    scopus 로고
    • Compartmental analysis of R2 measurements of hepatic lipid and iron in vivo using breath-hold multi-echo 1H spectroscopy (HISTO)
    • Montreal, Canada
    • Sharma P, Kitajima HD, Zhong X, Kalb B, Martin DR. Compartmental analysis of R2 measurements of hepatic lipid and iron in vivo using breath-hold multi-echo 1H spectroscopy (HISTO). In: Proc 19th Annual Meeting ISMRM, Montreal, Canada; 2011. p 738.
    • (2011) thAnnual Meeting ISMRM , pp. 738
    • Sharma, P.1    Kitajima, H.D.2    Zhong, X.3    Kalb, B.4    Martin, D.R.5
  • 80
    • 84904067094 scopus 로고    scopus 로고
    • Effect of gadolinium-based contrast agent on the relaxation properties of water and fat in human liver as measured in vivo by 1H MRS
    • Salt Lake City
    • Hamilton G, Middleton M, Cunha G, Sirlin C. Effect of gadolinium-based contrast agent on the relaxation properties of water and fat in human liver as measured in vivo by 1H MRS. In: Proc 21st Annual Meeting ISMRM, Salt Lake City; 2013. p 815.
    • (2013) st Annual Meeting ISMRM , pp. 815
    • Hamilton, G.1    Middleton, M.2    Cunha, G.3    Sirlin, C.4
  • 81
    • 77955290109 scopus 로고    scopus 로고
    • Separate MRI quantification of dispersed (ferritin-like) and aggregated (hemosiderin-like) storage iron
    • Jensen JH, Tang H, Tosti CL, et al. Separate MRI quantification of dispersed (ferritin-like) and aggregated (hemosiderin-like) storage iron. Magn Reson Med 2010;63:1201-1209.
    • (2010) Magn Reson Med , vol.63 , pp. 1201-1209
    • Jensen, J.H.1    Tang, H.2    Tosti, C.L.3
  • 82
    • 84892832121 scopus 로고    scopus 로고
    • MR characterization of hepatic storage iron in transfusional iron overload
    • Tang H, Jensen JH, Sammet CL, et al. MR characterization of hepatic storage iron in transfusional iron overload. J Magn Reson Imaging 2014;39:307-316.
    • (2014) J Magn Reson Imaging , vol.39 , pp. 307-316
    • Tang, H.1    Jensen, J.H.2    Sammet, C.L.3
  • 83
    • 84886769267 scopus 로고    scopus 로고
    • Multipeak fat-corrected complex R2∗ relaxometry: Theory, optimization, and clinical validation
    • Hernando D, Kramer HJ, Reeder SB. Multipeak fat-corrected complex R2∗ relaxometry: theory, optimization, and clinical validation. Magn Reson Med 2013;70:1319-1331.
    • (2013) Magn Reson Med , vol.70 , pp. 1319-1331
    • Hernando, D.1    Kramer, H.J.2    Reeder, S.B.3
  • 85
    • 55749111009 scopus 로고    scopus 로고
    • Myocardial T2∗ measurements in iron-overloaded thalassemia: An in vivo study to investigate optimal methods of quantification
    • He T, Gatehouse PD, Smith GC, Mohiaddin RH, Pennell DJ, Firmin DN. Myocardial T2∗ measurements in iron-overloaded thalassemia: An in vivo study to investigate optimal methods of quantification. Magn Reson Med 2008;60:1082-1089.
    • (2008) Magn Reson Med , vol.60 , pp. 1082-1089
    • He, T.1    Gatehouse, P.D.2    Smith, G.C.3    Mohiaddin, R.H.4    Pennell, D.J.5    Firmin, D.N.6
  • 86
    • 78650297326 scopus 로고    scopus 로고
    • Improved R2∗ measurement accuracy with absolute SNR truncation and optimal coil combination
    • Yin X, Shah S, Katsaggelos AK, Larson AC. Improved R2∗ measurement accuracy with absolute SNR truncation and optimal coil combination. NMR Biomed 2010;23:1127-1136.
    • (2010) NMR Biomed , vol.23 , pp. 1127-1136
    • Yin, X.1    Shah, S.2    Katsaggelos, A.K.3    Larson, A.C.4
  • 87
    • 84913619751 scopus 로고    scopus 로고
    • Improved pixel-by-pixel MRI R2∗ relaxometry by nonlocal means
    • Epub ahead of print
    • Feng Y, He T, Feng M, et al. Improved pixel-by-pixel MRI R2∗ relaxometry by nonlocal means. Magn Reson Med [Epub ahead of print].
    • Magn Reson Med
    • Feng, Y.1    He, T.2    Feng, M.3
  • 88
    • 84255178974 scopus 로고    scopus 로고
    • Estimation of liver T∗2 in transfusion-related iron overload in patients with weighted least squares T∗2 IDEAL
    • Vasanawala SS, Yu H, Shimakawa A, Jeng M, Brittain JH. Estimation of liver T∗2 in transfusion-related iron overload in patients with weighted least squares T∗2 IDEAL. Magn Reson Med 2012;67:183-190.
    • (2012) Magn Reson Med , vol.67 , pp. 183-190
    • Vasanawala, S.S.1    Yu, H.2    Shimakawa, A.3    Jeng, M.4    Brittain, J.H.5
  • 89
    • 77951585972 scopus 로고    scopus 로고
    • Phase and amplitude correction for multi-echo water-fat separation with bipolar acquisitions
    • Yu H, Shimakawa A, McKenzie CA, et al. Phase and amplitude correction for multi-echo water-fat separation with bipolar acquisitions. J Magn Reson Imaging 2010;31:1264-1271.
    • (2010) J Magn Reson Imaging , vol.31 , pp. 1264-1271
    • Yu, H.1    Shimakawa, A.2    Mckenzie, C.A.3
  • 90
    • 12144259379 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy to measure hepatic triglyceride content: Prevalence of hepatic steatosis in the general population
    • Szczepaniak LS, Nurenberg P, Leonard D, et al. Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population. Am J Physiol Endocrinol Metab 2005;288: 462-468.
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , pp. 462-468
    • Szczepaniak, L.S.1    Nurenberg, P.2    Leonard, D.3
  • 91
    • 84874225277 scopus 로고    scopus 로고
    • R2∗ estimation using inphase echoes in the presence of fat: The effects of complex spectrum of fat
    • Hernando D, Kuhn JP, Mensel B, et al. R2∗ estimation using "inphase" echoes in the presence of fat: the effects of complex spectrum of fat. J Magn Reson Imaging 2013;37:717-726.
    • (2013) J Magn Reson Imaging , vol.37 , pp. 717-726
    • Hernando, D.1    Kuhn, J.P.2    Mensel, B.3
  • 92
    • 0029118345 scopus 로고
    • Osteoporosis: Clinical assessment with quantitative MR imaging in diagnosis
    • Wehrli FW, Ford JC, Haddad JG. Osteoporosis: clinical assessment with quantitative MR imaging in diagnosis. Radiology 1995;196:631-641.
    • (1995) Radiology , vol.196 , pp. 631-641
    • Wehrli, F.W.1    Ford, J.C.2    Haddad, J.G.3
  • 93
    • 18244403164 scopus 로고    scopus 로고
    • Limits of detection of SPIO at 3.0 T using T2∗ relaxometry
    • Dahnke H, Schaeffter T. Limits of detection of SPIO at 3.0 T using T2∗ relaxometry. Magn Reson Med 2005;53:1202-1206.
    • (2005) Magn Reson Med , vol.53 , pp. 1202-1206
    • Dahnke, H.1    Schaeffter, T.2
  • 97
    • 84866605548 scopus 로고    scopus 로고
    • Effect of multipeak spectral modeling of fat for liver iron and fat quantification: Correlation of biopsy with MR imaging results
    • Kuhn JP, Hernando D, Munoz Del Rio A, et al. Effect of multipeak spectral modeling of fat for liver iron and fat quantification: correlation of biopsy with MR imaging results. Radiology 2012; 265:133-142.
    • (2012) Radiology , vol.265 , pp. 133-142
    • Kuhn, J.P.1    Hernando, D.2    Munoz Del Rio, A.3
  • 98
    • 0033816884 scopus 로고    scopus 로고
    • Postprocessing technique to correct for background gradients in image-based R∗(2) measurements
    • Fernandez-Seara MA, Wehrli FW. Postprocessing technique to correct for background gradients in image-based R∗(2) measurements. Magn Reson Med 2000;44:358-366.
    • (2000) Magn Reson Med , vol.44 , pp. 358-366
    • Fernandez-Seara, M.A.1    Wehrli, F.W.2
  • 99
    • 0036240237 scopus 로고    scopus 로고
    • Cerebral oxygen extraction fraction and cerebral venous blood volume measurements using MRI: Effects of magnetic field variation
    • An H, Lin W. Cerebral oxygen extraction fraction and cerebral venous blood volume measurements using MRI: effects of magnetic field variation. Magn Reson Med 2002;47:958-966.
    • (2002) Magn Reson Med , vol.47 , pp. 958-966
    • An, H.1    Lin, W.2
  • 100
    • 77955285465 scopus 로고    scopus 로고
    • Postprocessing correction for distortions in T2∗ decay caused by quadratic cross-slice B0 inhomogeneity
    • Yang X, Sammet S, Schmalbrock P, Knopp MV. Postprocessing correction for distortions in T2∗ decay caused by quadratic cross-slice B0 inhomogeneity. Magn Reson Med 2010;63:1258- 1268.
    • (2010) Magn Reson Med , vol.63 , pp. 1258-1268
    • Yang, X.1    Sammet, S.2    Schmalbrock, P.3    Knopp, M.V.4
  • 101
    • 67650097317 scopus 로고    scopus 로고
    • Rapid single-scan T2∗- mapping using exponential excitation pulses and image-based correction for linear background gradients
    • Baudrexel S, Volz S, Preibisch C, et al. Rapid single-scan T2∗- mapping using exponential excitation pulses and image-based correction for linear background gradients. Magn Reson Med 2009;62:263-268.
    • (2009) Magn Reson Med , vol.62 , pp. 263-268
    • Baudrexel, S.1    Volz, S.2    Preibisch, C.3
  • 102
    • 84865500545 scopus 로고    scopus 로고
    • R2∗ mapping in the presence of macroscopic B(0) field variations
    • Hernando D, Vigen KK, Shimakawa A, Reeder SB. R2∗ mapping in the presence of macroscopic B(0) field variations. Magn Reson Med 2012;68:830-840.
    • (2012) Magn Reson Med , vol.68 , pp. 830-840
    • Hernando, D.1    Vigen, K.K.2    Shimakawa, A.3    Reeder, S.B.4
  • 103
    • 18044399191 scopus 로고    scopus 로고
    • Cardiovascular T2-star (T2∗) magnetic resonance for the early diagnosis of myocardial iron overload
    • Anderson LJ, Holden S, Davis B, et al. Cardiovascular T2-star (T2∗) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J 2001;22:2171-2179.
    • (2001) Eur Heart J , vol.22 , pp. 2171-2179
    • Anderson, L.J.1    Holden, S.2    Davis, B.3
  • 104
    • 66549115170 scopus 로고    scopus 로고
    • R2∗ magnetic resonance imaging of the liver in patients with iron overload
    • Hankins JS, McCarville MB, Loeffler RB, et al. R2∗ magnetic resonance imaging of the liver in patients with iron overload. Blood 2009;113:4853-4855.
    • (2009) Blood , vol.113 , pp. 4853-4855
    • Hankins, J.S.1    McCarville, M.B.2    Loeffler, R.B.3
  • 105
    • 64249125576 scopus 로고    scopus 로고
    • MRI assessment of liver iron content in thalassamic patients with three different protocols: Comparisons and correlations
    • Christoforidis A, Perifanis V, Spanos G, et al. MRI assessment of liver iron content in thalassamic patients with three different protocols: comparisons and correlations. Eur J Haematol 2009; 82:388-392.
    • (2009) Eur J Haematol , vol.82 , pp. 388-392
    • Christoforidis, A.1    Perifanis, V.2    Spanos, G.3
  • 107
    • 0242365594 scopus 로고    scopus 로고
    • Interscanner reproducibility of cardiovascular magnetic resonance T2∗ measurements of tissue iron in thalassemia
    • Westwood MA, Anderson LJ, Firmin DN, et al. Interscanner reproducibility of cardiovascular magnetic resonance T2∗ measurements of tissue iron in thalassemia. J Magn Reson Imaging 2003;18:616-620.
    • (2003) J Magn Reson Imaging , vol.18 , pp. 616-620
    • Westwood, M.A.1    Anderson, L.J.2    Firmin, D.N.3
  • 108
    • 26444604415 scopus 로고    scopus 로고
    • Intercentre reproducibility of magnetic resonance T2∗ measurements of myocardial iron in thalassaemia
    • Westwood MA, Firmin DN, Gildo M, et al. Intercentre reproducibility of magnetic resonance T2∗ measurements of myocardial iron in thalassaemia. Int J Cardiovasc Imaging 2005;21:531-538.
    • (2005) Int J Cardiovasc Imaging , vol.21 , pp. 531-538
    • Westwood, M.A.1    Firmin, D.N.2    Gildo, M.3
  • 109
    • 33750030695 scopus 로고    scopus 로고
    • Thalassemia International Federation Heart TI multi-center validation of the transferability of the magnetic resonance T2∗ technique for the quantification of tissue iron
    • Tanner MA, He T, Westwood MA, Firmin DN, Pennell DJ, Thalassemia International Federation Heart TI. Multi-center validation of the transferability of the magnetic resonance T2∗ technique for the quantification of tissue iron. Haematologica 2006;91:1388-1391.
    • (2006) Haematologica , vol.91 , pp. 1388-1391
    • Tanner, M.A.1    He, T.2    Westwood, M.A.3    Firmin, D.N.4    Pennell, D.J.5
  • 110
    • 67650079955 scopus 로고    scopus 로고
    • Multicenter validation of the magnetic resonance T2∗ technique for segmental and global quantification of myocardial iron
    • Ramazzotti A, Pepe A, Positano V, et al. Multicenter validation of the magnetic resonance T2∗ technique for segmental and global quantification of myocardial iron. J Magn Reson Imaging 2009; 30:62-68.
    • (2009) J Magn Reson Imaging , vol.30 , pp. 62-68
    • Ramazzotti, A.1    Pepe, A.2    Positano, V.3
  • 111
    • 77955365667 scopus 로고    scopus 로고
    • International reproducibility of single breathhold T2∗ MR for cardiac and liver iron assessment among five thalassemia centers
    • Kirk P, He T, Anderson LJ, et al. International reproducibility of single breathhold T2∗ MR for cardiac and liver iron assessment among five thalassemia centers. J Magn Reson Imaging 2010; 32:315-319.
    • (2010) J Magn Reson Imaging , vol.32 , pp. 315-319
    • Kirk, P.1    He, T.2    Anderson, L.J.3
  • 112
    • 84878518118 scopus 로고    scopus 로고
    • The use of appropriate calibration curves corrects for systematic differences in liver R2∗ values measured using different software packages
    • Meloni A, Rienhoff HY Jr, Jones A, Pepe A, Lombardi M, Wood JC. The use of appropriate calibration curves corrects for systematic differences in liver R2∗ values measured using different software packages. Br J Haematol 2013;161:888-891.
    • (2013) Br J Haematol , vol.161 , pp. 888-891
    • Meloni, A.1    Rienhoff, H.Y.2    Jones, A.3    Pepe, A.4    Lombardi, M.5    Wood, J.C.6
  • 113
    • 84913605283 scopus 로고    scopus 로고
    • Robustness of R2∗ mapping for liver iron assessment at 1.5T and 3T
    • Salt Lake City
    • Qazi N, Hernando D, Reeder SB. Robustness of R2∗ mapping for liver iron assessment at 1.5T and 3T. In: Proc 21st Annual Meeting ISMRM, Salt Lake City; 2013.
    • (2013) stAnnual Meeting ISMRM
    • Qazi, N.1    Hernando, D.2    Reeder, S.B.3
  • 115
    • 84902508379 scopus 로고    scopus 로고
    • Hepatic iron quantification on 3 Tesla (3 T) magnetic resonance (MR): Technical challenges and solutions
    • Anwar M, Wood J, Manwani D, Taragin B, Oyeku SO, Peng Q. Hepatic iron quantification on 3 Tesla (3 T) magnetic resonance (MR): technical challenges and solutions. Radiol Res Pract 2013; 2013:628150.
    • (2013) Radiol Res Pract 2013 , pp. 628150
    • Anwar, M.1    Wood, J.2    Manwani, D.3    Taragin, B.4    Oyeku, S.O.5    Peng, Q.6
  • 116
    • 84863835374 scopus 로고    scopus 로고
    • Feasibility, reproducibility, and reliability for the T∗2 iron evaluation at 3 T in comparison with 1.5 T
    • Meloni A, Positano V, Keilberg P, et al. Feasibility, reproducibility, and reliability for the T∗2 iron evaluation at 3 T in comparison with 1.5 T. Magn Reson Med 2012;68:543-551.
    • (2012) Magn Reson Med , vol.68 , pp. 543-551
    • Meloni, A.1    Positano, V.2    Keilberg, P.3
  • 117
    • 84913616181 scopus 로고    scopus 로고
    • Single breathhold 3D radial imaging for R2∗ and fat fraction quantification in the liver
    • Salt Lake City
    • Taviani V, Johnson KM, Hernando D, Reeder SB. Single breathhold 3D radial imaging for R2∗ and fat fraction quantification in the liver. In: Proc 21st Annual Meeting ISMRM. Salt Lake City; 2013. p 2449.
    • (2013) Proc 21st Annual Meeting ISMRM , pp. 2449
    • Taviani, V.1    Johnson, K.M.2    Hernando, D.3    Reeder, S.B.4
  • 118
    • 84862821279 scopus 로고    scopus 로고
    • Cardiac T2 measurements in patients with iron overload: A comparison of imaging parameters and analysis techniques
    • Ou P, Zhao Y, Fawal SE, Banka P, Powell AJ. Cardiac T2 measurements in patients with iron overload: a comparison of imaging parameters and analysis techniques. Magn Reson Imaging 2012;30:641-648.
    • (2012) Magn Reson Imaging , vol.30 , pp. 641-648
    • Ou, P.1    Zhao, Y.2    Fawal, S.E.3    Banka, P.4    Powell, A.J.5
  • 119
    • 0027973923 scopus 로고
    • Theory of NMR signal behavior in magnetically inhomogeneous tissues: The static dephasing regime
    • Yablonskiy DA, Haacke EM. Theory of NMR signal behavior in magnetically inhomogeneous tissues: the static dephasing regime. Magn Reson Med 1994;32:749-763.
    • (1994) Magn Reson Med , vol.32 , pp. 749-763
    • Yablonskiy, D.A.1    Haacke, E.M.2
  • 120
    • 0028507749 scopus 로고
    • Effects of spatial distribution on proton relaxation enhancement by particulate iron oxide
    • Tanimoto A, Pouliquen D, Kreft BP, Stark DD. Effects of spatial distribution on proton relaxation enhancement by particulate iron oxide. J Magn Reson Imaging 1994;4:653-657.
    • (1994) J Magn Reson Imaging , vol.4 , pp. 653-657
    • Tanimoto, A.1    Pouliquen, D.2    Kreft, B.P.3    Stark, D.D.4
  • 122
    • 0028321471 scopus 로고
    • Microscopic susceptibility variation and transverse relaxation: Theory and experiment
    • Weisskoff RM, Zuo CS, Boxerman JL, Rosen BR. Microscopic susceptibility variation and transverse relaxation: theory and experiment. Magn Reson Med 1994;31:601-610.
    • (1994) Magn Reson Med , vol.31 , pp. 601-610
    • Weisskoff, R.M.1    Zuo, C.S.2    Boxerman, J.L.3    Rosen, B.R.4
  • 123
    • 0036660189 scopus 로고    scopus 로고
    • Effects of iron overload and hepatitis C virus positivity in determining progression of liver fibrosis in thalassemia following bone marrow transplantation
    • Angelucci E, Muretto P, Nicolucci A, et al. Effects of iron overload and hepatitis C virus positivity in determining progression of liver fibrosis in thalassemia following bone marrow transplantation. Blood 2002;100:17-21.
    • (2002) Blood , vol.100 , pp. 17-21
    • Angelucci, E.1    Muretto, P.2    Nicolucci, A.3
  • 124
    • 21244475972 scopus 로고    scopus 로고
    • Liver iron concentration evaluated by two magnetic methods: Magnetic resonance imaging and magnetic susceptometry
    • Carneiro AA, Fernandes JP, de Araujo DB, et al. Liver iron concentration evaluated by two magnetic methods: magnetic resonance imaging and magnetic susceptometry. Magn Reson Med 2005;54:122-128.
    • (2005) Magn Reson Med , vol.54 , pp. 122-128
    • Carneiro, A.A.1    Fernandes, J.P.2    De Araujo, D.B.3
  • 125
    • 75349104448 scopus 로고    scopus 로고
    • Diffusion-weighted MR imaging of the liver
    • Taouli B, Koh DM. Diffusion-weighted MR imaging of the liver. Radiology 2010;254:47-66.
    • (2010) Radiology , vol.254 , pp. 47-66
    • Taouli, B.1    Koh, D.M.2
  • 126
    • 85027929392 scopus 로고    scopus 로고
    • Evaluation of MR imaging with T1 and T2∗ mapping for the determination of hepatic iron overload
    • Henninger B, Kremser C, Rauch S, et al. Evaluation of MR imaging with T1 and T2∗ mapping for the determination of hepatic iron overload. Eur Radiol 2012;22:2478-2486.
    • (2012) Eur Radiol , vol.22 , pp. 2478-2486
    • Henninger, B.1    Kremser, C.2    Rauch, S.3
  • 127
    • 23044475721 scopus 로고    scopus 로고
    • Cardiac iron determines cardiac T2∗, T2, and T1 in the gerbil model of iron cardiomyopathy
    • Wood JC, Otto-Duessel M, Aguilar M, et al. Cardiac iron determines cardiac T2∗, T2, and T1 in the gerbil model of iron cardiomyopathy. Circulation 2005;112:535-543.
    • (2005) Circulation , vol.112 , pp. 535-543
    • Wood, J.C.1    Otto-Duessel, M.2    Aguilar, M.3
  • 128
    • 84883376884 scopus 로고    scopus 로고
    • In vivo comparison of myocardial T1 with T2 and T2∗ in thalassaemia major
    • Feng Y, He T, Carpenter JP, et al. In vivo comparison of myocardial T1 with T2 and T2∗ in thalassaemia major. J Magn Reson Imaging 2013;38:588-593.
    • (2013) J Magn Reson Imaging , vol.38 , pp. 588-593
    • Feng, Y.1    He, T.2    Carpenter, J.P.3
  • 129
    • 73349121926 scopus 로고    scopus 로고
    • Quantitative susceptibility map reconstruction from MR phase data using bayesian regularization: Validation and application to brain imaging
    • de Rochefort L, Liu T, Kressler B, et al. Quantitative susceptibility map reconstruction from MR phase data using bayesian regularization: validation and application to brain imaging. Magn Reson Med 2010;63:194-206.
    • (2010) Magn Reson Med , vol.63 , pp. 194-206
    • De Rochefort, L.1    Liu, T.2    Kressler, B.3
  • 130
    • 53549101684 scopus 로고    scopus 로고
    • Quantitative MR susceptibility mapping using piece-wise constant regularized inversion of the magnetic field
    • de Rochefort L, Brown R, Prince MR, Wang Y. Quantitative MR susceptibility mapping using piece-wise constant regularized inversion of the magnetic field. Magn Reson Med 2008;60:1003-1009.
    • (2008) Magn Reson Med , vol.60 , pp. 1003-1009
    • De Rochefort, L.1    Brown, R.2    Prince, M.R.3    Wang, Y.4
  • 131
    • 84855422550 scopus 로고    scopus 로고
    • Morphology enabled dipole inversion for quantitative susceptibility mapping using structural consistency between the magnitude image and the susceptibility map
    • Liu J, Liu T, de Rochefort L, et al. Morphology enabled dipole inversion for quantitative susceptibility mapping using structural consistency between the magnitude image and the susceptibility map. Neuroimage 2012;59:2560-2568.
    • (2012) Neuroimage , vol.59 , pp. 2560-2568
    • Liu, J.1    Liu, T.2    De Rochefort, L.3
  • 132
    • 84863522265 scopus 로고    scopus 로고
    • Quantitative susceptibility mapping (QSM) as a means to measure brain iron? A post mortem validation study
    • Langkammer C, Schweser F, Krebs N, et al. Quantitative susceptibility mapping (QSM) as a means to measure brain iron? A post mortem validation study. Neuroimage 2012;62:1593-1599.
    • (2012) Neuroimage , vol.62 , pp. 1593-1599
    • Langkammer, C.1    Schweser, F.2    Krebs, N.3
  • 133
    • 0028545115 scopus 로고
    • MR susceptometry: An external-phantom method for measuring bulk susceptibility from field-echo phase reconstruction maps
    • Holt RW, Diaz PJ, Duerk JL, Bellon EM. MR susceptometry: an external-phantom method for measuring bulk susceptibility from field-echo phase reconstruction maps. J Magn Reson Imaging 1994;4:809-818.
    • (1994) J Magn Reson Imaging , vol.4 , pp. 809-818
    • Holt, R.W.1    Diaz, P.J.2    Duerk, J.L.3    Bellon, E.M.4
  • 135
    • 10044235369 scopus 로고    scopus 로고
    • MRImeasurement of hepatic magnetic susceptibility-phantom validation and normal subject studies
    • Chu Z, Cohen AR, Muthupillai R, Chung T, Wang ZJ. MRImeasurement of hepatic magnetic susceptibility-phantom validation and normal subject studies. Magn Reson Med 2004;52:1318- 1327.
    • (2004) Magn Reson Med , vol.52 , pp. 1318-1327
    • Chu, Z.1    Cohen, A.R.2    Muthupillai, R.3    Chung, T.4    Wang, Z.J.5
  • 136
    • 0033210818 scopus 로고    scopus 로고
    • Magnetic resonance imaging measurement of volume magnetic susceptibility using a boundary condition
    • Wang ZJ, Li S, Haselgrove JC. Magnetic resonance imaging measurement of volume magnetic susceptibility using a boundary condition. J Magn Reson 1999;140:477-481.
    • (1999) J Magn Reson , vol.140 , pp. 477-481
    • Wang, Z.J.1    Li, S.2    Haselgrove, J.C.3
  • 137
    • 77649342535 scopus 로고    scopus 로고
    • Assessment of cardiac iron by MRI susceptometry and R2∗ in patients with thalassemia
    • Wang ZJ, Fischer R, Chu Z, et al. Assessment of cardiac iron by MRI susceptometry and R2∗ in patients with thalassemia. Magn Reson Imaging 2010;28:363-371.
    • (2010) Magn Reson Imaging , vol.28 , pp. 363-371
    • Wang, Z.J.1    Fischer, R.2    Chu, Z.3
  • 138
    • 84859790450 scopus 로고    scopus 로고
    • Simultaneous field and R2∗ mapping to quantify liver iron content using autoregressive moving average modeling
    • published erratum appears in J Magn Reson Imaging, early view
    • Taylor BA, Loeffler RB, Song R, McCarville MB, Hankins JS, Hillenbrand CM. Simultaneous field and R2∗ mapping to quantify liver iron content using autoregressive moving average modeling. J Magn Reson Imaging 2012;35:1125-1132 [published erratum appears in J Magn Reson Imaging, early view, doi 1110.1002/jmri.24135].
    • (2012) J Magn Reson Imaging , vol.35 , pp. 1125-1132
    • Taylor, B.A.1    Loeffler, R.B.2    Song, R.3    McCarville, M.B.4    Hankins, J.S.5    Hillenbrand, C.M.6
  • 139
    • 84883253342 scopus 로고    scopus 로고
    • Magnetic susceptibility as a B0 field strength independent MRI biomarker of liver iron overload
    • Hernando D, Cook RJ, Diamond C, Reeder SB. Magnetic susceptibility as a B0 field strength independent MRI biomarker of liver iron overload. Magn Reson Med 2013;70:648-656.
    • (2013) Magn Reson Med , vol.70 , pp. 648-656
    • Hernando, D.1    Cook, R.J.2    Diamond, C.3    Reeder, S.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.