Iron overload in the liver diagnostic and quantification

European Journal of Radiology

Volumn 61, Issue 3, 2007, Pages 499-506

  Alústiza, Jose M ^a   Castiella, Agustin ^a   De Juan, Maria D ^a   Emparanza, Jose I ^a   Artetxe, Jose ^a   Uranga, Maite ^a  

^a OSATEK   (Spain)

Author keywords

Hemochromatosis 761.659; Liver biopsy 761.1261; Liver diseases 761.659; Magnetic resonance (MR) comparative studies 761.121411, 761.121412

Indexed keywords

BIOLOGICAL ORGANS; DISEASES; GENETIC ENGINEERING; IRON; MAGNETIC RESONANCE;

HEMOCHROMATOSIS; HEPATIC IRON QUANTIFICATION; LIVER BIOPSY; MAGNETIC RESONANCE (MR) COMPARATIVE STUDIES;

BIOPSY;

DIAGNOSTIC PROCEDURE; GENETIC ANALYSIS; HEMOCHROMATOSIS; HUMAN; IRON OVERLOAD; LIVER BIOPSY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; REPRODUCIBILITY; REVIEW; SYSTEMATIC REVIEW; VALIDATION PROCESS;

HEMOCHROMATOSIS; HUMANS; IRON; LIVER; MAGNETIC RESONANCE IMAGING;

EID: 33847184238     PISSN: 0720048X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejrad.2006.11.012     Document Type: Review

References (33)

1. Brittenham G.M., and Badman D.G. Noninvasive measurement of iron: report of an NIDDK workshop. Blood 101 1 (2003) 15-19 Epub August 29, 2002, Review
2. ÓNeil J., and Powell L. Clinical aspects of hemochromatosis. Semin Liver Dis 25 4 (2005) 381-391 Review
3. Sherlock S., and Dooley J. Diseases of the liver and biliary system. 11th ed. (2002), Blackwell Scientific Publications, Oxford pp. 399-411
4. Pietrangelo A. Hereditary hemochromatosis-A new look at an old disease. N Engl J Med 350 (2004) 2383-2397
5. Siegelman E.S., and Mitchell D.G. In: Semelka R.C. (Ed). Abdominal iron deposition: metabolism, MR findings, and clinical importance. Radiology 199 1 (1996) 13-22
6. Tavill A.S. Diagnosis and management of hemochromatosis. Hepatology 33 5 (2001) 1321-1328
7. EASL International Consensus Conference on Haemochromatosis. J Hepatol 33 3 (2000) 485-504 Review
8. Gandon Y., Olivié D., Guyader D., et al. Non-invasive assessment of hepatic iron stores by MRI. The Lancet 363 9406 (2004) 357-362
9. Porter J.B. Liver iron measurement by MRI. Blood 105 2 (2005) 437
10. Feder J.N., Gnirke A., Thomas W., et al. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet 13 4 (1996) 399-408
11. Beutler E. The HFE Cys282Tyr mutation as a necessary but not sufficient cause of clinical hereditary hemochromatosis. Blood 101 9 (2003) 3347-3350
12. Le Gac G., Dupradeau F.Y., Mura C., et al. Phenotypic expression of the C282Y/Q283P compound heterozygosity in HFE and molecular modeling of the Q283P mutation effect. Blood Cells Mol Dis 30 3 (2003) 231-237
13. De Juan D., Reta A., Castiella A., et al. HFE gene mutations analysis in Basque hereditary haemochromatosis patients and controls. Eur J Hum Genet 9 12 (2001) 961-964
14. Lazarescu A., Snively B.M., and Adams P.C. Phenotype variation in C282Y homozygotes for the hemochromatosis gene. Clin Gastroenterol Hepatol 3 10 (2005) 1043-1046
15. Powell L.W., Dixon J.L., Ramm G.A., et al. Screening for hemochromatosis in asymptomatic subjects with or without a family history. Arch Intern Med 166 (2006) 269-270
16. Bonkovsky H.L., Rubin R.B., Cable E.E., et al. Hepatic iron concentration: noninvasive estimation by means of MR imaging techniques. Radiology 212 1 (1999) 227-234
17. Jensen P.D. Evaluation of iron overload. Br J Haematol 124 6 (2004) 697-711 Rew.
18. St Pierre T.G., Clark P.R., Chua-anusorn W., et al. Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance. Blood 105 2 (2005) 855-861 Epub July 15, 2004
19. Rose C., Vandevenne P., et al. Liver iron content assessment by routine and simple magnetic resonance imaging procedure in highly transfused patients. Eur J Haematol 77 (2006) 145-149
20. Anderson L.J., Holden S., et al. Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J 22 (2001) 2171-2179
21. Papakonstantinou O., Kostaridou S., et al. Quantification of liver iron overload by T2 quantitative magnetic resonance imaging in Thalassemia: impact of chronic hepatitis c on measurements. J Pediatr Hematol/Oncol 21 2 (1999) 142-148 March/April
22. Westwood M.A., Anderson L.J., et al. Interscanner reproducibility of cardiovascular magnetic resonance T2* measurements of tissue iron in thalassemia. J Magn Resonan Imag 18 (2003) 616-620
23. Westwood M.A., Anderson L.J., et al. A single breath-hold multiecho T2* cardiovascular magnetic resonance technique for diagnosis of myocardial iron overload. J Magn Resonan Imag 18 (2003) 33-39
24. * mapping accurately estimates hepatic iron concentration in transfusion-dependent thalassemia and sickle cell disease patients. Blood 106 4 (2005) 1460-1465
25. Alústiza J.M., Artetxe J., Castiella A., et al. MR quantification of hepatic iron concentration. Radiology 230 (2004) 479-484
26. Gandon Y., Guyader D., Heautot J.F., et al. Hemochromatosis: diagnosis and quantification of liver iron with gradient-echo MR imaging. Radiology 193 2 (1994) 533-538
27. Ernst O., Sergent G., Bonvarlet P., et al. Hepatic iron overload: diagnosis and quantification with MR imaging. AJR 168 5 (1997) 1205-1208
28. Ernst O., Rose C., Sergent G., et al. Hepatic iron overload: quantification with MR imaging at 1.5 T. AJR 172 4 (1999) 1141-1142
29. Gandon Y. Iron and liver. Available at: http://www.radio.univ-rennes1.fr.
30. Alústiza JM, Emparanza JI, et al. Phantom for the standardisation of the quantification of liver iron concentration (LIC) using MRI. The European Iron Club (EIC). 28th-29th September 2006; Barcelona, Spain. Abstracts Book. P-072.
31. St. Pierre TG, Jeffrey GP, Rossi E, et al. A new model for predicting venesection therapy requirements in hereditary hemochromatosis using non-invasive liver iron concentration measurement. Blood (ASH Annual Meeting Abstracts) 2005; 106:Abst.3596.
32. Edwards C.Q., and Kushner J.P. Screening for hemochromatosis. N Engl J Med 328 22 (1993) 1616-1620
33. Castiella A., Alústiza J.M., et al. Hereditary Hemochromatosis. N Engl J Med 351 12 (2004) 1263-1264