메뉴 건너뛰기




Volumn 30, Issue 7, 2012, Pages 926-933

Use of fat suppression in R2 relaxometry with MRI for the quantification of tissue iron overload in beta-thalassemic patients

Author keywords

Fat suppression; Iron overload; MRI; R2 relaxometry; Thalassemia

Indexed keywords

DEFERIPRONE; DEFEROXAMINE; FERRITIN; IRON; LIPID;

EID: 84864017879     PISSN: 0730725X     EISSN: 18735894     Source Type: Journal    
DOI: 10.1016/j.mri.2012.03.002     Document Type: Article
Times cited : (22)

References (35)
  • 1
    • 23744459788 scopus 로고    scopus 로고
    • MRI R2 and R2* mapping accurately estimates hepatic iron concentration in transfusion-dependent thalassemia and sickle cell disease patients
    • Wood C., Enriquez C., Ghugre N., et al. MRI R2 and R2* mapping accurately estimates hepatic iron concentration in transfusion-dependent thalassemia and sickle cell disease patients. Blood 2005, 106:1460-1465.
    • (2005) Blood , vol.106 , pp. 1460-1465
    • Wood, C.1    Enriquez, C.2    Ghugre, N.3
  • 2
    • 11244355277 scopus 로고    scopus 로고
    • Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance
    • St Pierre T.G., Clark P.R., Chua-anusorn W., et al. Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance. Blood 2005, 105:855-861.
    • (2005) Blood , vol.105 , pp. 855-861
    • St Pierre, T.G.1    Clark, P.R.2    Chua-anusorn, W.3
  • 3
    • 31944446136 scopus 로고    scopus 로고
    • R2 relaxometry with MRI for the quantification of tissue iron overload in beta- thalassemic patients
    • Alexopoulou E., Stripeli F., Baras P., et al. R2 relaxometry with MRI for the quantification of tissue iron overload in beta- thalassemic patients. J Magn Reson Imaging 2006, 23:163-170.
    • (2006) J Magn Reson Imaging , vol.23 , pp. 163-170
    • Alexopoulou, E.1    Stripeli, F.2    Baras, P.3
  • 4
    • 4544301060 scopus 로고    scopus 로고
    • Magnetic resonance imaging in the evaluation of iron overload in patients with beta thalassemia and sickle cell disease
    • Voskaridou E., Douskou M., Terpos E., et al. Magnetic resonance imaging in the evaluation of iron overload in patients with beta thalassemia and sickle cell disease. Br J Haematol 2004, 126:736-742.
    • (2004) Br J Haematol , vol.126 , pp. 736-742
    • Voskaridou, E.1    Douskou, M.2    Terpos, E.3
  • 5
    • 7944230624 scopus 로고    scopus 로고
    • Myocardiac iron clearance during reversal of siderotic cardiomyopathy with intravenous desferrioxamine: a prospective study using T2* cardiovascular magnetic resonance
    • Anderson L.J., Westwood M.A., Holden S., et al. Myocardiac iron clearance during reversal of siderotic cardiomyopathy with intravenous desferrioxamine: a prospective study using T2* cardiovascular magnetic resonance. Br J Haematol 2004, 127:348-355.
    • (2004) Br J Haematol , vol.127 , pp. 348-355
    • Anderson, L.J.1    Westwood, M.A.2    Holden, S.3
  • 6
    • 29744439189 scopus 로고    scopus 로고
    • Measurement and mapping of liver iron concentrations using magnetic resonance imaging
    • St Pierre T.G., Clark P.R., Chua- anusorn W. Measurement and mapping of liver iron concentrations using magnetic resonance imaging. Ann NY Sci 2005, 1054:379-385.
    • (2005) Ann NY Sci , vol.1054 , pp. 379-385
    • St Pierre, T.G.1    Clark, P.R.2    Chua-anusorn, W.3
  • 7
    • 33845900683 scopus 로고    scopus 로고
    • Four-year evaluation of myocardial and liver iron assessed prospectively with serial MR scans in young patients with beta thalassemia major: comparison between different chelation regimens
    • Christoforidis A., Haritandi A., Tsiatra I., et al. Four-year evaluation of myocardial and liver iron assessed prospectively with serial MR scans in young patients with beta thalassemia major: comparison between different chelation regimens. Eur J Haematol 2007, 78:52-55.
    • (2007) Eur J Haematol , vol.78 , pp. 52-55
    • Christoforidis, A.1    Haritandi, A.2    Tsiatra, I.3
  • 8
    • 34547732864 scopus 로고    scopus 로고
    • Improved transverse relaxation rate measurement techniques for the assessment of hepatic myocardial iron content
    • Song R., Cohen A.R., Song H.K. Improved transverse relaxation rate measurement techniques for the assessment of hepatic myocardial iron content. J Magn Reson Imaging 2007, 26:208-214.
    • (2007) J Magn Reson Imaging , vol.26 , pp. 208-214
    • Song, R.1    Cohen, A.R.2    Song, H.K.3
  • 9
    • 0028365239 scopus 로고
    • Precision, accuracy and image plane uniformity in NMR relaxation time imaging on a 1.5T whole body MR imaging system
    • Andersen C., Jensen F.T. Precision, accuracy and image plane uniformity in NMR relaxation time imaging on a 1.5T whole body MR imaging system. Magn Reson Imaging 1994, 12:775-784.
    • (1994) Magn Reson Imaging , vol.12 , pp. 775-784
    • Andersen, C.1    Jensen, F.T.2
  • 10
    • 33750030695 scopus 로고    scopus 로고
    • Multicenter validation of the transferability of the magnetic resonance T2* technique for the quantification of tissue iron
    • Tanner M.A., He T., Westwood M.A., et al. Multicenter validation of the transferability of the magnetic resonance T2* technique for the quantification of tissue iron. Haematologica 2006, 91:1388-1391.
    • (2006) Haematologica , vol.91 , pp. 1388-1391
    • Tanner, M.A.1    He, T.2    Westwood, M.A.3
  • 11
    • 64249125576 scopus 로고    scopus 로고
    • MRI assessment of liver iron content in thalassemic patients with three different protocols: comparisons and correlations
    • Christoforidis A., Perifanis V., Spanos G., et al. MRI assessment of liver iron content in thalassemic patients with three different protocols: comparisons and correlations. Eur J Haematol 2009, 82:388-392.
    • (2009) Eur J Haematol , vol.82 , pp. 388-392
    • Christoforidis, A.1    Perifanis, V.2    Spanos, G.3
  • 12
    • 0842283228 scopus 로고    scopus 로고
    • Non-invasive assessment of hepatic iron stores by MRI
    • Gandon Y., Olivié D., Guyader D., et al. Non-invasive assessment of hepatic iron stores by MRI. The Lancet 2004, 363:357-362.
    • (2004) The Lancet , vol.363 , pp. 357-362
    • Gandon, Y.1    Olivié, D.2    Guyader, D.3
  • 13
    • 9144273737 scopus 로고    scopus 로고
    • MR quantification of hepatic iron concentration
    • Alústiza J., Artetxe J., Castiella A., et al. MR quantification of hepatic iron concentration. Radiology 2004, 230:479-484.
    • (2004) Radiology , vol.230 , pp. 479-484
    • Alústiza, J.1    Artetxe, J.2    Castiella, A.3
  • 14
    • 30344471110 scopus 로고    scopus 로고
    • Iron chelation treatment with combined therapy with deferiprone and deferoxamine: a 12-month trial
    • Kattamis A., Ladis V., Berdousi H., et al. Iron chelation treatment with combined therapy with deferiprone and deferoxamine: a 12-month trial. Blood Cells Mol Dis 2006, 36:21-25.
    • (2006) Blood Cells Mol Dis , vol.36 , pp. 21-25
    • Kattamis, A.1    Ladis, V.2    Berdousi, H.3
  • 15
    • 78649306862 scopus 로고    scopus 로고
    • Magnetic resonance imaging quantification of liver iron
    • Sirlin C.B., Reeder S.B. Magnetic resonance imaging quantification of liver iron. Magn Reson Imaging Clin N Am 2010, 18:359-381.
    • (2010) Magn Reson Imaging Clin N Am , vol.18 , pp. 359-381
    • Sirlin, C.B.1    Reeder, S.B.2
  • 16
    • 33846452882 scopus 로고    scopus 로고
    • Liver fat: effect of hepatic iron deposition on evaluation with opposed-phase MR imaging
    • Westphalen A., Qayyum A., Yeh B., et al. Liver fat: effect of hepatic iron deposition on evaluation with opposed-phase MR imaging. Radiology 2007, 242:450-455.
    • (2007) Radiology , vol.242 , pp. 450-455
    • Westphalen, A.1    Qayyum, A.2    Yeh, B.3
  • 17
    • 39549097104 scopus 로고    scopus 로고
    • Liver fat and iron at in-phase and opposed-phase MR imaging
    • Alústiza J.M., Castiella A. Liver fat and iron at in-phase and opposed-phase MR imaging. Radiology 2008, 246:641.
    • (2008) Radiology , vol.246 , pp. 641
    • Alústiza, J.M.1    Castiella, A.2
  • 18
    • 65249141150 scopus 로고    scopus 로고
    • Assessment of iron distribution between liver, spleen, pancreas, bone marrow and myocardium by means of R2 relaxometry with MRI in patients with β-thalassemia major
    • Papakonstantinou O., Alexopoulou E., Economopoulos N., Benekos O., Kattamis A., Kostaridou S., et al. Assessment of iron distribution between liver, spleen, pancreas, bone marrow and myocardium by means of R2 relaxometry with MRI in patients with β-thalassemia major. J Magn Reson Imaging 2009, 29:853-859.
    • (2009) J Magn Reson Imaging , vol.29 , pp. 853-859
    • Papakonstantinou, O.1    Alexopoulou, E.2    Economopoulos, N.3    Benekos, O.4    Kattamis, A.5    Kostaridou, S.6
  • 19
    • 36348960664 scopus 로고    scopus 로고
    • MRI evaluation of tissue iron burden in patients with β-thalassemia major
    • Argyropoulou M.I., Astrakas A. MRI evaluation of tissue iron burden in patients with β-thalassemia major. Pediatr Radiol 2007, 37:1191-1200.
    • (2007) Pediatr Radiol , vol.37 , pp. 1191-1200
    • Argyropoulou, M.I.1    Astrakas, A.2
  • 20
    • 36348940441 scopus 로고    scopus 로고
    • Liver, bone marrow, pancreas and pituitary gland iron overload in young and adult thalassemic patients: a T2 relaxometry study
    • Argyropoulou M.I., Kiortsis D.N., Astrakas L., Metafratzi Z., Chalissos N., Efremidis S.C. Liver, bone marrow, pancreas and pituitary gland iron overload in young and adult thalassemic patients: a T2 relaxometry study. Eur Radiol 2007, 17:3025-3030.
    • (2007) Eur Radiol , vol.17 , pp. 3025-3030
    • Argyropoulou, M.I.1    Kiortsis, D.N.2    Astrakas, L.3    Metafratzi, Z.4    Chalissos, N.5    Efremidis, S.C.6
  • 21
    • 0842287261 scopus 로고    scopus 로고
    • Magnetic resonance screening of iron status in transfusion-dependent beta-thalassemia patients
    • Ooi G.C., Khong P.L., Chan G.C., et al. Magnetic resonance screening of iron status in transfusion-dependent beta-thalassemia patients. Br J Haematol 2004, 124:385-390.
    • (2004) Br J Haematol , vol.124 , pp. 385-390
    • Ooi, G.C.1    Khong, P.L.2    Chan, G.C.3
  • 22
    • 38549150853 scopus 로고    scopus 로고
    • A T2* magnetic resonance imaging study of pancreatic iron overload in thalassemia major
    • Au W., Lam W., Chu W., et al. A T2* magnetic resonance imaging study of pancreatic iron overload in thalassemia major. Haematologica 2008, 93:116-119.
    • (2008) Haematologica , vol.93 , pp. 116-119
    • Au, W.1    Lam, W.2    Chu, W.3
  • 23
    • 0033042948 scopus 로고    scopus 로고
    • MR imaging of pancreatic changes in patients with transfusion-dependent beta-thalassemia major
    • Midiri M., Lo Casto A., Sparacia G., et al. MR imaging of pancreatic changes in patients with transfusion-dependent beta-thalassemia major. AJR Am J Roentgenol 1999, 173:187-192.
    • (1999) AJR Am J Roentgenol , vol.173 , pp. 187-192
    • Midiri, M.1    Lo Casto, A.2    Sparacia, G.3
  • 24
    • 34248654567 scopus 로고    scopus 로고
    • The pancreas in beta-thalassemia major: MR imaging features and correlation with iron stores and glucose disturbances
    • Papakonstantinou O., Ladis V., Kostaridou S., et al. The pancreas in beta-thalassemia major: MR imaging features and correlation with iron stores and glucose disturbances. Eur Radiol 2007, 17:1535-1543.
    • (2007) Eur Radiol , vol.17 , pp. 1535-1543
    • Papakonstantinou, O.1    Ladis, V.2    Kostaridou, S.3
  • 25
    • 34547135935 scopus 로고    scopus 로고
    • Bone marrow changes in beta-thalassemia major: quantitative MR imaging findings and correlation with iron stores
    • Drakonaki E., Maris T., Papadakis A., Karantanas A. Bone marrow changes in beta-thalassemia major: quantitative MR imaging findings and correlation with iron stores. Eur Radiology 2007, 17:2079-2087.
    • (2007) Eur Radiology , vol.17 , pp. 2079-2087
    • Drakonaki, E.1    Maris, T.2    Papadakis, A.3    Karantanas, A.4
  • 27
    • 84863993743 scopus 로고    scopus 로고
    • Hepatic MR imaging for in vivo differentiation of steatosis, iron deposition and combined storage disorder: single-ratio in/opposed phase analysis vs dual-ratio Dixon discrimination
    • [in press]
    • Bashir M.R., Merkle E.M., Smith A.D., Boll D.T. Hepatic MR imaging for in vivo differentiation of steatosis, iron deposition and combined storage disorder: single-ratio in/opposed phase analysis vs dual-ratio Dixon discrimination. Eur J Radiol 2011, [in press].
    • (2011) Eur J Radiol
    • Bashir, M.R.1    Merkle, E.M.2    Smith, A.D.3    Boll, D.T.4
  • 28
    • 77950613420 scopus 로고    scopus 로고
    • Pilot study assessing differentiation of steatosis hepatis, hepatic iron overload, and combined disease using two-point Dixon MRI at 3 T: in vitro and in vivo results of a 2D decomposition technique
    • Boll D.T., Marin D., Redmon G.M., Zink S.I., Merkle E.M. Pilot study assessing differentiation of steatosis hepatis, hepatic iron overload, and combined disease using two-point Dixon MRI at 3 T: in vitro and in vivo results of a 2D decomposition technique. Am J Roentgenol 2010, 194:965-971.
    • (2010) Am J Roentgenol , vol.194 , pp. 965-971
    • Boll, D.T.1    Marin, D.2    Redmon, G.M.3    Zink, S.I.4    Merkle, E.M.5
  • 29
    • 0023522025 scopus 로고
    • RLSQ: T1, T2 and ρ calculations, combining ratios and least squares
    • In Den Kleef J.J.E., Cuppen J.J.M. RLSQ: T1, T2 and ρ calculations, combining ratios and least squares. Magn Reson Imaging 1987, 5:513-524.
    • (1987) Magn Reson Imaging , vol.5 , pp. 513-524
    • In Den Kleef, J.J.E.1    Cuppen, J.J.M.2
  • 30
    • 77953809119 scopus 로고    scopus 로고
    • Assessment of liver fat quantification in the presence of iron
    • Bydder M., Shiehmorteza M., Yokoo T., et al. Assessment of liver fat quantification in the presence of iron. Magn Reson Imaging 2010, 28:767-776.
    • (2010) Magn Reson Imaging , vol.28 , pp. 767-776
    • Bydder, M.1    Shiehmorteza, M.2    Yokoo, T.3
  • 31
    • 78649278546 scopus 로고    scopus 로고
    • Quantification of liver fat with magnetic resonance imaging
    • Reeder S.B., Sirlin C.B. Quantification of liver fat with magnetic resonance imaging. Magn Reson Imaging Clin N Am 2010, 18:337-357.
    • (2010) Magn Reson Imaging Clin N Am , vol.18 , pp. 337-357
    • Reeder, S.B.1    Sirlin, C.B.2
  • 32
    • 59649107524 scopus 로고    scopus 로고
    • T2* relaxometry in liver, pancreas, and spleen in a healthy cohort of one hundred twenty-nine subjects-correlation with age, gender, and serum ferritin
    • Schwenzer N.F., Machann J., Haap M.M., Martirosian P., Schraml C., Liebig G., et al. T2* relaxometry in liver, pancreas, and spleen in a healthy cohort of one hundred twenty-nine subjects-correlation with age, gender, and serum ferritin. Invest Radiol 2008, 43:854-860.
    • (2008) Invest Radiol , vol.43 , pp. 854-860
    • Schwenzer, N.F.1    Machann, J.2    Haap, M.M.3    Martirosian, P.4    Schraml, C.5    Liebig, G.6
  • 33
    • 77950442762 scopus 로고    scopus 로고
    • Pancreatic iron loading predicts cardiac iron loading in thalassemia major
    • Noetzli L.J., Papudesi J., Coates T.D., Wood J.C. Pancreatic iron loading predicts cardiac iron loading in thalassemia major. Blood 2009, 114:4021-4026.
    • (2009) Blood , vol.114 , pp. 4021-4026
    • Noetzli, L.J.1    Papudesi, J.2    Coates, T.D.3    Wood, J.C.4
  • 34
    • 0028821746 scopus 로고
    • Assessment of liver iron overload by T2-quantitative magnetic resonance imaging: correlation of T2-QMRI measurements with serum ferritin and histologic grading of siderosis
    • Papakonstantinou O.G., Maris T.G., Kostaridou V., Gouliamos A.D., Koutoulas G.K., Kalovidouris A.E., et al. Assessment of liver iron overload by T2-quantitative magnetic resonance imaging: correlation of T2-QMRI measurements with serum ferritin and histologic grading of siderosis. Magn Reson Imaging 1995, 13:967-977.
    • (1995) Magn Reson Imaging , vol.13 , pp. 967-977
    • Papakonstantinou, O.G.1    Maris, T.G.2    Kostaridou, V.3    Gouliamos, A.D.4    Koutoulas, G.K.5    Kalovidouris, A.E.6
  • 35
    • 0028839871 scopus 로고
    • The Rician distribution of noisy MRI data
    • Gudbjartsson H., Patz S. The Rician distribution of noisy MRI data. Magn Reson Med 1995, 34:910.
    • (1995) Magn Reson Med , vol.34 , pp. 910
    • Gudbjartsson, H.1    Patz, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.