FoxO transcription factors support oxidative stress resistance in human chondrocytes

Arthritis and Rheumatology

Volumn 66, Issue 12, 2014, Pages 3349-3358

  Akasaki, Yukio ^a   Alvarez Garcia, Oscar ^a   Saito, Masahiko ^a   Caramés, Beatriz ^a   Iwamoto, Yukihide ^b   Lotz, Martin K ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECANASE 1; BECLIN 1; CASPASE 3; CASPASE 7; CATALASE; CHEMERIN; DNA; GLUTATHIONE PEROXIDASE 1; INTERLEUKIN 1BETA; REACTIVE OXYGEN METABOLITE; SIRTUIN 1; SMALL INTERFERING RNA; TERT BUTYL HYDROPEROXIDE; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1; CASPASE 9; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, HUMAN; FOXO3 PROTEIN, HUMAN; OXIDIZING AGENT;

ADOLESCENT; ADULT; APOPTOSIS; ARTICLE; CARTILAGE CELL; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; ENZYME SYNTHESIS; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MTT ASSAY; OSTEOARTHRITIS; OXIDATIVE STRESS; PLASMID; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; AGED; ARTICULAR CARTILAGE; AUTOPHAGY; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED; PHYSIOLOGY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; APOPTOSIS; AUTOPHAGY; CARTILAGE, ARTICULAR; CASPASE 3; CASPASE 9; CELL SURVIVAL; CHONDROCYTES; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1BETA; MIDDLE AGED; OXIDANTS; OXIDATIVE STRESS; RNA, SMALL INTERFERING; TERT-BUTYLHYDROPEROXIDE; YOUNG ADULT;

EID: 84912019205     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.38868     Document Type: Article

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