Induction of hypertrophic chondrocyte-like phenotypes by oxidized LDL in cultured bovine articular chondrocytes through increase in oxidative stress

Osteoarthritis and Cartilage

Volumn 18, Issue 10, 2010, Pages 1284-1290

  Kishimoto, H ^a   Akagi, M ^a   Zushi, S ^a   Teramura, T ^b   Onodera, Y ^b   Sawamura, T ^c   Hamanishi, C ^a  

^a KINKI UNIVERSITY   (Japan)

^b KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Chondrocyte hypertrophy; COL10; LOX 1; Oxidative stress; Oxidized LDL; Runx2

Indexed keywords

ACETYLCYSTEINE; COLLAGEN TYPE 10; MESSENGER RNA; OXIDIZED LOW DENSITY LIPOPROTEIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX2;

ANIMAL EXPERIMENT; ARTICLE; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL DIFFERENTIATION; EXTRACELLULAR MATRIX; FEMALE; GROWTH PLATE; IMMUNOFLUORESCENCE TEST; NONHUMAN; OSTEOARTHRITIS; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

ACETYLCYSTEINE; ALKALINE PHOSPHATASE; ANIMALS; ANTIOXIDANTS; CARTILAGE, ARTICULAR; CATTLE; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE X; CORE BINDING FACTOR ALPHA 1 SUBUNIT; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HYDROGEN PEROXIDE; HYPERTROPHY; LIPOPROTEINS, LDL; MICROSCOPY, FLUORESCENCE; OXIDATIVE STRESS; PHENOTYPE; RNA, MESSENGER; SCAVENGER RECEPTORS, CLASS E;

EID: 77956884110     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2010.05.021     Document Type: Article

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