Increased sensitivity to ionizing radiation by targeting the homologous recombination pathway in glioma initiating cells

Molecular Oncology

Volumn 8, Issue 8, 2014, Pages 1603-1615

  Lim, Yi Chieh ^a,b   Roberts, Tara L ^a,b   Day, Bryan W ^a   Stringer, Brett W ^a   Kozlov, Sergei ^a   Fazry, Shazrul ^a   Bruce, Zara C ^a   Ensbey, Kathleen S ^a   Walker, David G ^c   Boyd, Andrew W ^a   Lavin, Martin F ^a,b  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c WESLEY HOSPITAL   (Australia)

Author keywords

ATM inhibitor; DNA damage; DNA double strand break repair; Glioma initiating cell; Homologous recombination; Neural progenitor cell

Indexed keywords

1 (2 HYDROXY 4 MORPHOLIN 4 YL PHENYL)PHENYL METHANONE; 2 MORPHOLINO 6 (1 THIANTHRENYL) 4 PYRANONE; DNA; PROTEIN SERINE THREONINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER STEM CELL; CANCER SURVIVAL; CELL DEATH; CONTROLLED STUDY; DNA END JOINING REPAIR; GLIOMA; GLIOMA INITIATION CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; MOUSE; NONHUMAN; PROTEIN AGGREGATION; RADIOSENSITIVITY; RADIOSENSITIZATION;

EID: 84911982553     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2014.06.012     Document Type: Article

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