Smg1 haploinsufficiency predisposes to tumor formation and inflammation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 4, 2013, Pages

  Roberts, Tara L ^a,b   Ho, Uda ^a   Luff, John ^a   Lee, C Soon ^c   Apte, Simon H ^a   MacDonald, Kelli P A ^a   Raggat, Liza J ^b   Pettit, Allison R ^b   Morrow, Carl A ^b   Waters, Michael J ^b   Chen, Phil ^a   Woods, Rick G ^a   Thomas, Gethin P ^b   Pierre, Liam St ^a   Farah, Camile S ^b   Clarke, Raymond A ^c   Brown, James A L ^d   Lavin, Martin F ^a,b  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c UNIVERSITY OF WESTERN SYDNEY   (Australia)

^d NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROTEIN; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SMG1 PROTEIN; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CANCER INCIDENCE; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CHRONIC INFLAMMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; GENOTYPE; HAPLOINSUFFICIENCY; HETEROZYGOTE; HOMOZYGOSITY; IMMUNE SYSTEM; LIFESPAN; LOSS OF FUNCTION MUTATION; LUNG ADENOCARCINOMA; LYMPHOMA; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; STRESS; T LYMPHOCYTE;

ANIMALS; BASE SEQUENCE; DISEASE MODELS, ANIMAL; DNA, COMPLEMENTARY; GENETIC PREDISPOSITION TO DISEASE; HAPLOINSUFFICIENCY; HEMATOLOGIC NEOPLASMS; HOMOZYGOTE; INFLAMMATION; LUNG NEOPLASMS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; NEOPLASMS, EXPERIMENTAL; PROTEIN-SERINE-THREONINE KINASES;

ANIMALIA; MUS;

EID: 84872842115     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1215696110     Document Type: Article

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