Potential of the synthetic lethality principle

Science

Volumn 342, Issue 6160, 2013, Pages 809-811

  Nijman, Sebastian M B ^a   Friend, Stephen H ^b  

^a ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^b SAGE BIONETWORKS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; EPIDERMAL GROWTH FACTOR; MYC PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN P53; RAS PROTEIN; RETINOBLASTOMA PROTEIN; RETINOBLASTOMA PROTEIN 1; UNCLASSIFIED DRUG; TUMOR SUPPRESSOR PROTEIN;

CANCER; DISEASE TREATMENT;

CAENORHABDITIS ELEGANS; CARCINOGENESIS; DNA REPAIR; DROSOPHILA MELANOGASTER; FEEDBACK SYSTEM; GENE MUTATION; LETHALITY; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; SACCHAROMYCES CEREVISIAE; SHORT SURVEY; SIGNAL TRANSDUCTION; SYNTHETIC LETHALITY; ANIMAL; GENE TARGETING; GENE THERAPY; GENETICS; HUMAN; IMMUNOTHERAPY; LETHAL GENE; MODIFIER GENE; MOLECULARLY TARGETED THERAPY; MUTATION; NEOPLASMS; PROCEDURES; ARTICLE; METHODOLOGY;

ANIMALS; DROSOPHILA MELANOGASTER; GENE TARGETING; GENES, LETHAL; GENES, MODIFIER; GENETIC THERAPY; HUMANS; IMMUNOTHERAPY; MOLECULAR TARGETED THERAPY; MUTATION; NEOPLASMS; SACCHAROMYCES CEREVISIAE; TUMOR SUPPRESSOR PROTEINS;

EID: 84887662629     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1244669     Document Type: Short Survey

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