Overexpression of heme Oxygenase 1 causes cognitive decline and affects pathways for tauopathy in Mice

Journal of Alzheimer's Disease

Volumn 43, Issue 2, 2015, Pages 519-534

  Wang, Dayong ^a,b   Yang, Huia ^a,b   Yahui, Penga ^a,b   Tang, Lu ^a,b   Jin, Jianfeng ^a,b   He, Rongzhang ^a,b   Li, Yanze ^a,b   Zhang, Shuai ^a,b   Li, Lisha ^a,b   Zhou, You ^a,b   Li, Jing ^a,b   Ma, Ning ^a,b   Li, Jihong ^a,b   Li, Sijia ^a,b   Gao, Xu ^a,b   Luo, Shanshun ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b State Province Key Laboratories of Biomedicine Pharmaceutics of China   (China)

Author keywords

Alzheimer's disease; CDK5; heme oxygenase 1; iron; tau truncation; tauopathies

Indexed keywords

CYCLIN DEPENDENT KINASE 5; HEME OXYGENASE 1; IRON; REACTIVE OXYGEN METABOLITE; TAU PROTEIN; GLUTAMIC ACID; MESSENGER RNA; PROTOPORPHYRIN; PROTOPORPHYRIN COBALT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; LONG TERM CARE; MENTAL DETERIORATION; MORRIS WATER MAZE TEST; MOUSE; NERVE CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; TAUOPATHY; TRANSGENIC MOUSE; ANIMAL; BRAIN; C57BL MOUSE; COGNITIVE DEFECT; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MAZE TEST; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; REACTION TIME; SPATIAL LEARNING;

ANIMALS; BRAIN; COGNITION DISORDERS; CYCLIN-DEPENDENT KINASE 5; GENE EXPRESSION REGULATION; GLUTAMIC ACID; HEME OXYGENASE-1; HUMANS; IRON; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PHOSPHORYLATION; PROTOPORPHYRINS; REACTION TIME; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SPATIAL LEARNING; TAUOPATHIES;

EID: 84911913522     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-140567     Document Type: Article

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