Activation of the Nrf2/HO-1 antioxidant pathway contributes to the protective effects of lycium barbarum polysaccharides in the rodent retina after ischemia-reperfusion-induced damage

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  He, Meihua ^a,b   Pan, Hong ^a,b   Chang, Raymond Chuen Chung ^c,d   So, Kwok Fai ^c,d,e   Brecha, Nicholas C ^f,g,h   Pu, Mingliang ^a,b  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b PEKING UNIVERSITY   (China)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

^e JINAN UNIVERSITY   (China)

^f UNIVERSITY OF HONG KONG   (Hong Kong)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEME OXYGENASE 1; POLYSACCHARIDE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFICACY; IMMUNOFLUORESCENCE TEST; INTRAOCULAR HYPERTENSION; LYCIUM BARBARUM; MALE; NERVE CELL; NEUROPROTECTION; NONHUMAN; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; RETINA AMACRINE CELL; RETINA BIPOLAR GANGLION CELL; RETINA INJURY; SIGNAL TRANSDUCTION; TREATMENT DURATION;

AMACRINE CELLS; ANIMALS; APOPTOSIS; CELL NUCLEUS; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HEME OXYGENASE-1; LYCIUM; MALE; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROTEIN TRANSPORT; RATS; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; RETINA; RETINAL GANGLION CELLS; SIGNAL TRANSDUCTION;

EID: 84896455283     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0084800     Document Type: Article

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