Bile acid signaling in lipid metabolism: Metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1851, Issue 1, 2015, Pages 19-29

  Qi, Yunpeng ^a,b   Jiang, Changtao ^a   Cheng, Jie ^a,c   Krausz, Kristopher W ^a   Li, Tiangang ^c   Ferrell, Jessica M ^c   Gonzalez, Frank J ^a   Chiang, John Y L ^c  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c Northeastern Ohio Medical University   (United States)

Author keywords

bile acid metabolism; CYP7A1; farnesoid X receptor (FXR); lipidomics; tauro muricholic acid

Indexed keywords

3 HYDROXYACYL COENZYME A DEHYDROGENASE; ACETYL COENZYME A ACYLTRANSFERASE; BILE ACID; BIOLOGICAL MARKER; CD36 ANTIGEN; CERAMIDE; CHOLESTEROL 7ALPHA MONOOXYGENASE; ENOYL COENZYME A HYDRATASE; FARNESOID X RECEPTOR; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; LONG CHAIN 3 HYDROXYACYL COENZYME A DEHYDROGENASE; LYSOPHOSPHATIDYLCHOLINE; MESSENGER RNA; PALMITOYL COENZYME A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; SPHINGOMYELIN; TAURINE; TAURINE TRANSPORTER; TAURO BETA MURICHOLIC ACID; TAUROCHENODEOXYCHOLIC ACID; TAUROCHOLIC ACID; TAURODEOXYCHOLIC ACID; TAUROHYODEOXYCHOLIC ACID; TAUROURSODEOXYCHOLIC ACID; UNCLASSIFIED DRUG; CYP7A1 PROTEIN, MOUSE; GLUCOSE; TAUROMURICHOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE ACID SYNTHESIS; CONTROLLED STUDY; DIABETES MELLITUS; ELECTROSPRAY MASS SPECTROMETRY; FATTY ACID OXIDATION; FATTY LIVER; FEMALE; GENE OVEREXPRESSION; INSULIN RESISTANCE; LIPID DIET; LIPID METABOLISM; LIPIDOMICS; MALE; METABOLOMICS; MOUSE; NONHUMAN; OBESITY; QUADRUPOLE MASS SPECTROMETRY; SIGNAL TRANSDUCTION; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; GENETICS; HOMEOSTASIS; INTESTINE; LIVER; METABOLISM; METABOLOME; PHYSIOLOGY; PROCEDURES; RAT; TRANSGENIC MOUSE;

MUS;

ANIMALS; BILE ACIDS AND SALTS; CHOLESTEROL 7-ALPHA-HYDROXYLASE; DIABETES MELLITUS; DIET, HIGH-FAT; FEMALE; GLUCOSE; HOMEOSTASIS; INSULIN RESISTANCE; INTESTINES; LIPID METABOLISM; LIVER; MALE; METABOLOME; METABOLOMICS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OBESITY; RATS; SIGNAL TRANSDUCTION; TAUROCHOLIC ACID;

EID: 84911484567     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2014.04.008     Document Type: Article

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