Muricholic bile acids are potent regulators of bile acid synthesis via a positive feedback mechanism

Journal of Internal Medicine

Volumn 275, Issue 1, 2014, Pages 27-38

  Hu, X ^a   Bonde, Y ^a   Eggertsen, G ^a   Rudling, M ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Antagonist; Apical sodium dependent bile acid transporter; Fibroblast growth factor 15; Muricholic acid; Steroid 12 alpha hydroxylase

Indexed keywords

AMPICILLIN; BILE ACID; CHENODEOXYCHOLIC ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLIC ACID; DEOXYCHOLIC ACID; FARNESOID X RECEPTOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 15; LITHOCHOLIC ACID; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC THERAPY; ARTICLE; BILE ACID SYNTHESIS; BILE DUCT LIGATION; BILIARY EXCRETION; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GERMFREE ANIMAL; INTESTINE; LIVER; MASS FRAGMENTOGRAPHY; MOUSE; NONHUMAN; PHENOTYPE; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANTAGONIST; APICAL SODIUM-DEPENDENT BILE ACID TRANSPORTER; FIBROBLAST GROWTH FACTOR 15; MURICHOLIC ACID; STEROID 12-ALPHA HYDROXYLASE;

AMPICILLIN; ANIMALS; ANTI-BACTERIAL AGENTS; BILE ACIDS AND SALTS; CHOLESTEROL 7-ALPHA-HYDROXYLASE; CHOLIC ACIDS; FEEDBACK, PHYSIOLOGICAL; FEMALE; FIBROBLAST GROWTH FACTORS; INTESTINES; LIVER; MICE; MICE, KNOCKOUT; MODELS, ANIMAL; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STEROID 12-ALPHA-HYDROXYLASE; SYMPORTERS;

EID: 84890214004     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/joim.12140     Document Type: Article

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