Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes

Hepatology

Volumn 42, Issue 6, 2005, Pages 1291-1299

  Dent, Paul ^a,b   Fang, Youwen ^a,b   Gupta, Seema ^c   Studer, Elaine ^b   Mitchell, Glint ^a   Spiegel, Sarah ^a   Hylemon, Philip B ^b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; BILE ACID CONJUGATE; CHENODEOXYCHOLIC ACID; DEOXYCHOLIC ACID; EPIDERMAL GROWTH FACTOR RECEPTOR; G PROTEIN COUPLED RECEPTOR; GLYCOCHENODEOXYCHOLIC ACID; GLYCOCHOLIC ACID; GLYCODEOXYCHOLIC ACID; GUANOSINE TRIPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PERTUSSIS TOXIN; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TAUROCHENODEOXYCHOLIC ACID; TAUROCHOLIC ACID; TAURODEHYDROCHOLIC ACID; TAUROURSODEOXYCHOLIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

ANIMALS; BILE ACIDS AND SALTS; CELLS, CULTURED; ENZYME ACTIVATION; GLYCOCHENODEOXYCHOLIC ACID; HEPATOCYTES; MALE; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PERTUSSIS TOXIN; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TAURODEOXYCHOLIC ACID;

EID: 32944455840     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.20942     Document Type: Article

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