-
2
-
-
84875886251
-
Regulation of A20 and other OTU deubiquitinases by reversible oxidation
-
Kulathu Y., Garcia F.J., Mevissen T.E.T., Busch M., Arnaudo N., Carroll K.S., Barford D., Komander D. Regulation of A20 and other OTU deubiquitinases by reversible oxidation. Nat Commun 2013, 4:1569.
-
(2013)
Nat Commun
, vol.4
, pp. 1569
-
-
Kulathu, Y.1
Garcia, F.J.2
Mevissen, T.E.T.3
Busch, M.4
Arnaudo, N.5
Carroll, K.S.6
Barford, D.7
Komander, D.8
-
3
-
-
84871699184
-
Deubiquitinases as a signaling target of oxidative stress
-
Cotto-Rios X.M., Békés M., Chapman J., Ueberheide B., Huang T.T. Deubiquitinases as a signaling target of oxidative stress. Cell Rep 2012, 2:1475-1484.
-
(2012)
Cell Rep
, vol.2
, pp. 1475-1484
-
-
Cotto-Rios, X.M.1
Békés, M.2
Chapman, J.3
Ueberheide, B.4
Huang, T.T.5
-
4
-
-
84856708042
-
Phosphorylation-dependent activity of the deubiquitinase DUBA
-
Huang O.W., Ma X., Yin J., Flinders J., Maurer T., Kayagaki N., Phung Q., Bosanac I., Arnott D., Dixit V.M., et al. Phosphorylation-dependent activity of the deubiquitinase DUBA. Nat Struct Mol Biol 2012, 19:171-175.
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 171-175
-
-
Huang, O.W.1
Ma, X.2
Yin, J.3
Flinders, J.4
Maurer, T.5
Kayagaki, N.6
Phung, Q.7
Bosanac, I.8
Arnott, D.9
Dixit, V.M.10
-
5
-
-
84880931087
-
Deubiquitylases from genes to organism
-
Clague M.J., Barsukov I., Coulson J.M., Liu H., Rigden D.J., Urbé S. Deubiquitylases from genes to organism. Physiol Rev 2013, 93:1289-1315.
-
(2013)
Physiol Rev
, vol.93
, pp. 1289-1315
-
-
Clague, M.J.1
Barsukov, I.2
Coulson, J.M.3
Liu, H.4
Rigden, D.J.5
Urbé, S.6
-
6
-
-
68049084674
-
Breaking the chains: structure and function of the deubiquitinases
-
Komander D., Clague M.J., Urbé S. Breaking the chains: structure and function of the deubiquitinases. Nat Rev Mol Cell Biol 2009, 10:550-563.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 550-563
-
-
Komander, D.1
Clague, M.J.2
Urbé, S.3
-
7
-
-
84878832998
-
OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis
-
Mevissen T.E.T., Hospenthal M.K., Geurink P.P., Elliott P.R., Akutsu M., Arnaudo N., Ekkebus R., Kulathu Y., Wauer T., Oualid El F., et al. OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis. Cell 2013, 154:169-184.
-
(2013)
Cell
, vol.154
, pp. 169-184
-
-
Mevissen, T.E.T.1
Hospenthal, M.K.2
Geurink, P.P.3
Elliott, P.R.4
Akutsu, M.5
Arnaudo, N.6
Ekkebus, R.7
Kulathu, Y.8
Wauer, T.9
Oualid, E.F.10
-
8
-
-
84555218153
-
The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types
-
Faesen A.C., Luna-Vargas M.P.A., Geurink P.P., Clerici M., Merkx R., van Dijk W.J., Hameed D.S., Oualid El F., Ovaa H., Sixma T.K. The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types. Chem Biol 2011, 18:1550-1561.
-
(2011)
Chem Biol
, vol.18
, pp. 1550-1561
-
-
Faesen, A.C.1
Luna-Vargas, M.P.A.2
Geurink, P.P.3
Clerici, M.4
Merkx, R.5
van Dijk, W.J.6
Hameed, D.S.7
Oualid El, F.8
Ovaa, H.9
Sixma, T.K.10
-
9
-
-
84907358982
-
Screening of DUB activity and specificity by MALDI-TOF mass spectrometry
-
Ritorto M.S., Ewan R., Perez-Oliva A.B., Knebel A., Buhrlage S.J., Wightman M., Kelly S.M., Wood N.T., Virdee S., Gray N.S., et al. Screening of DUB activity and specificity by MALDI-TOF mass spectrometry. Nat Commun 2014, 5:4763.
-
(2014)
Nat Commun
, vol.5
, pp. 4763
-
-
Ritorto, M.S.1
Ewan, R.2
Perez-Oliva, A.B.3
Knebel, A.4
Buhrlage, S.J.5
Wightman, M.6
Kelly, S.M.7
Wood, N.T.8
Virdee, S.9
Gray, N.S.10
-
10
-
-
39049183044
-
Regulation and function of IKK and IKK-related kinases
-
Hacker H., Karin M. Regulation and function of IKK and IKK-related kinases. Sci Signal 2006, 2006:re13-re13.
-
(2006)
Sci Signal
, vol.2006
, pp. re13-re13
-
-
Hacker, H.1
Karin, M.2
-
11
-
-
16344378618
-
Cell biology. Kinasing and clipping down the NF-κB trail
-
van Oers N.S.C., Chen Z.J. Cell biology. Kinasing and clipping down the NF-κB trail. Science 2005, 308:65-66.
-
(2005)
Science
, vol.308
, pp. 65-66
-
-
van Oers, N.S.C.1
Chen, Z.J.2
-
12
-
-
84858113865
-
No one can whistle a symphony alone - how different ubiquitin linkages cooperate to orchestrate NF-κB activity
-
Schmukle A.C., Walczak H. No one can whistle a symphony alone - how different ubiquitin linkages cooperate to orchestrate NF-κB activity. J Cell Sci 2012, 125:549-559.
-
(2012)
J Cell Sci
, vol.125
, pp. 549-559
-
-
Schmukle, A.C.1
Walczak, H.2
-
13
-
-
0032135131
-
SUMO-1 modification of IκBα Inhibits NF-κB activation
-
Desterro J.M., Rodriguez M.S., Hay R.T. SUMO-1 modification of IκBα Inhibits NF-κB activation. Mol Cell 1998, 2:233-239.
-
(1998)
Mol Cell
, vol.2
, pp. 233-239
-
-
Desterro, J.M.1
Rodriguez, M.S.2
Hay, R.T.3
-
14
-
-
78651488457
-
Interferon-stimulated gene 15 and the protein ISGylation system
-
Zhang D., Zhang D-E. Interferon-stimulated gene 15 and the protein ISGylation system. J Interferon Cytokine Res 2011, 31:119-130.
-
(2011)
J Interferon Cytokine Res
, vol.31
, pp. 119-130
-
-
Zhang, D.1
Zhang, D.-E.2
-
15
-
-
46249115827
-
Interferon-inducible antiviral effectors
-
Sadler A.J., Williams B.R.G. Interferon-inducible antiviral effectors. Nat Rev Immunol 2008, 8:559-568.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 559-568
-
-
Sadler, A.J.1
Williams, B.R.G.2
-
17
-
-
67649391002
-
Ubiquitination, ubiquitin-like modifiers, and deubiquitination in viral infection
-
Isaacson M.K., Ploegh H.L. Ubiquitination, ubiquitin-like modifiers, and deubiquitination in viral infection. Cell Host Microbe 2009, 5:559-570.
-
(2009)
Cell Host Microbe
, vol.5
, pp. 559-570
-
-
Isaacson, M.K.1
Ploegh, H.L.2
-
19
-
-
23744434659
-
A deubiquitinating enzyme encoded by HSV-1 belongs to a family of cysteine proteases that is conserved across the family Herpesviridae
-
Kattenhorn L.M., Korbel G.A., Kessler B.M., Spooner E., Ploegh H.L. A deubiquitinating enzyme encoded by HSV-1 belongs to a family of cysteine proteases that is conserved across the family Herpesviridae. Mol Cell 2005, 19:547-557.
-
(2005)
Mol Cell
, vol.19
, pp. 547-557
-
-
Kattenhorn, L.M.1
Korbel, G.A.2
Kessler, B.M.3
Spooner, E.4
Ploegh, H.L.5
-
20
-
-
29744463885
-
A deubiquitinating activity is conserved in the large tegument protein of the herpesviridae
-
Schlieker C., Korbel G.A., Kattenhorn L.M., Ploegh H.L. A deubiquitinating activity is conserved in the large tegument protein of the herpesviridae. J Virol 2005, 79:15582-15585.
-
(2005)
J Virol
, vol.79
, pp. 15582-15585
-
-
Schlieker, C.1
Korbel, G.A.2
Kattenhorn, L.M.3
Ploegh, H.L.4
-
21
-
-
29744463886
-
The papain-like protease from the severe acute respiratory syndrome coronavirus is a deubiquitinating enzyme
-
Lindner H.A., Fotouhi-Ardakani N., Lytvyn V., Lachance P., Sulea T., Ménard R. The papain-like protease from the severe acute respiratory syndrome coronavirus is a deubiquitinating enzyme. J Virol 2005, 79:15199-15208.
-
(2005)
J Virol
, vol.79
, pp. 15199-15208
-
-
Lindner, H.A.1
Fotouhi-Ardakani, N.2
Lytvyn, V.3
Lachance, P.4
Sulea, T.5
Ménard, R.6
-
22
-
-
29744455503
-
The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity
-
Barretto N., Jukneliene D., Ratia K., Chen Z., Mesecar A.D., Baker S.C. The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity. J Virol 2005, 79:15189-15198.
-
(2005)
J Virol
, vol.79
, pp. 15189-15198
-
-
Barretto, N.1
Jukneliene, D.2
Ratia, K.3
Chen, Z.4
Mesecar, A.D.5
Baker, S.C.6
-
23
-
-
77950806384
-
Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases
-
Clementz M.A., Chen Z., Banach B.S., Wang Y., Sun L., Ratia K., Baez-Santos Y.M., Wang J., Takayama J., Ghosh A.K., et al. Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases. J Virol 2010, 84:4619-4629.
-
(2010)
J Virol
, vol.84
, pp. 4619-4629
-
-
Clementz, M.A.1
Chen, Z.2
Banach, B.S.3
Wang, Y.4
Sun, L.5
Ratia, K.6
Baez-Santos, Y.M.7
Wang, J.8
Takayama, J.9
Ghosh, A.K.10
-
24
-
-
79952290477
-
Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease
-
James T.W., Frias-Staheli N., Bacik J-P., Levingston Macleod J.M., Khajehpour M., García-Sastre A., Mark B.L. Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:2222-2227.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 2222-2227
-
-
James, T.W.1
Frias-Staheli, N.2
Bacik, J.-P.3
Levingston Macleod, J.M.4
Khajehpour, M.5
García-Sastre, A.6
Mark, B.L.7
-
25
-
-
79952301200
-
Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains
-
Akutsu M., Ye Y., Virdee S., Chin J.W., Komander D. Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:2228-2233.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 2228-2233
-
-
Akutsu, M.1
Ye, Y.2
Virdee, S.3
Chin, J.W.4
Komander, D.5
-
26
-
-
0034711403
-
Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease
-
Orth K., Xu Z., Mudgett M.B., Bao Z.Q., Palmer L.E., Bliska J.B., Mangel W.F., Staskawicz B., Dixon J.E. Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease. Science 2000, 290:1594-1597.
-
(2000)
Science
, vol.290
, pp. 1594-1597
-
-
Orth, K.1
Xu, Z.2
Mudgett, M.B.3
Bao, Z.Q.4
Palmer, L.E.5
Bliska, J.B.6
Mangel, W.F.7
Staskawicz, B.8
Dixon, J.E.9
-
27
-
-
27944471038
-
Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-κB activation
-
Zhou H., Monack D.M., Kayagaki N., Wertz I., Yin J., Wolf B., Dixit V.M. Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-κB activation. J Exp Med 2005, 202:1327-1332.
-
(2005)
J Exp Med
, vol.202
, pp. 1327-1332
-
-
Zhou, H.1
Monack, D.M.2
Kayagaki, N.3
Wertz, I.4
Yin, J.5
Wolf, B.6
Dixit, V.M.7
-
28
-
-
33745186215
-
Chlamydia trachomatis-derived deubiquitinating enzymes in mammalian cells during infection
-
Misaghi S., Balsara Z.R., Catic A., Spooner E., Ploegh H.L., Starnbach M.N. Chlamydia trachomatis-derived deubiquitinating enzymes in mammalian cells during infection. Mol Microbiol 2006, 61:142-150.
-
(2006)
Mol Microbiol
, vol.61
, pp. 142-150
-
-
Misaghi, S.1
Balsara, Z.R.2
Catic, A.3
Spooner, E.4
Ploegh, H.L.5
Starnbach, M.N.6
-
29
-
-
0023039206
-
Synthesis and characterization of ubiquitin ethyl ester, a new substrate for ubiquitin carboxyl-terminal hydrolase
-
Wilkinson K.D., Cox M.J., Mayer A.N., Frey T. Synthesis and characterization of ubiquitin ethyl ester, a new substrate for ubiquitin carboxyl-terminal hydrolase. Biochemistry 1986, 25:6644-6649.
-
(1986)
Biochemistry
, vol.25
, pp. 6644-6649
-
-
Wilkinson, K.D.1
Cox, M.J.2
Mayer, A.N.3
Frey, T.4
-
30
-
-
0032539582
-
Kinetic and mechanistic studies on the hydrolysis of ubiquitin C-terminal 7-amido-4-methylcoumarin by deubiquitinating enzymes
-
Dang L.C., Melandri F.D., Stein R.L. Kinetic and mechanistic studies on the hydrolysis of ubiquitin C-terminal 7-amido-4-methylcoumarin by deubiquitinating enzymes. Biochemistry 1998, 37:1868-1879.
-
(1998)
Biochemistry
, vol.37
, pp. 1868-1879
-
-
Dang, L.C.1
Melandri, F.D.2
Stein, R.L.3
-
31
-
-
0032499752
-
Expressed protein ligation: a general method for protein engineering
-
Muir T.W., Sondhi D., Cole P.A. Expressed protein ligation: a general method for protein engineering. Proc Natl Acad Sci USA 1998, 95:6705-6710.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6705-6710
-
-
Muir, T.W.1
Sondhi, D.2
Cole, P.A.3
-
32
-
-
0035903538
-
A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14
-
Borodovsky A., Kessler B.M., Casagrande R., Overkleeft H.S., Wilkinson K.D., Ploegh H.L. A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14. EMBO J 2001, 20:5187-5196.
-
(2001)
EMBO J
, vol.20
, pp. 5187-5196
-
-
Borodovsky, A.1
Kessler, B.M.2
Casagrande, R.3
Overkleeft, H.S.4
Wilkinson, K.D.5
Ploegh, H.L.6
-
33
-
-
10744227299
-
Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins
-
Hemelaar J., Borodovsky A., Kessler B.M., Reverter D., Cook J., Kolli N., Gan-Erdene T., Wilkinson K.D., Gill G., Lima C.D., et al. Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins. Mol Cell Biol 2004, 24:84-95.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 84-95
-
-
Hemelaar, J.1
Borodovsky, A.2
Kessler, B.M.3
Reverter, D.4
Cook, J.5
Kolli, N.6
Gan-Erdene, T.7
Wilkinson, K.D.8
Gill, G.9
Lima, C.D.10
-
34
-
-
34547093612
-
Active-site directed probes to report enzymatic action in the ubiquitin proteasome system
-
Ovaa H. Active-site directed probes to report enzymatic action in the ubiquitin proteasome system. Nat Rev Cancer 2007, 7:613-620.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 613-620
-
-
Ovaa, H.1
-
35
-
-
78650446183
-
Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin
-
Oualid El F., Merkx R., Ekkebus R., Hameed D.S., Smit J.J., de Jong A., Hilkmann H., Sixma T.K., Ovaa H. Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin. Angew Chem Int Ed Engl 2010, 49:10149-10153.
-
(2010)
Angew Chem Int Ed Engl
, vol.49
, pp. 10149-10153
-
-
Oualid El, F.1
Merkx, R.2
Ekkebus, R.3
Hameed, D.S.4
Smit, J.J.5
de Jong, A.6
Hilkmann, H.7
Sixma, T.K.8
Ovaa, H.9
-
36
-
-
0031038169
-
Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome
-
Lam Y.A., Xu W., DeMartino G.N., Cohen R.E. Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome. Nature 1997, 385:737-740.
-
(1997)
Nature
, vol.385
, pp. 737-740
-
-
Lam, Y.A.1
Xu, W.2
DeMartino, G.N.3
Cohen, R.E.4
-
37
-
-
84874612259
-
On terminal alkynes that can react with active-site cysteine nucleophiles in proteases
-
Ekkebus R., van Kasteren S.I., Kulathu Y., Scholten A., Berlin I., Geurink P.P., de Jong A., Goerdayal S., Neefjes J., Heck A.J.R., et al. On terminal alkynes that can react with active-site cysteine nucleophiles in proteases. J Am Chem Soc 2013, 135:2867-2870.
-
(2013)
J Am Chem Soc
, vol.135
, pp. 2867-2870
-
-
Ekkebus, R.1
van Kasteren, S.I.2
Kulathu, Y.3
Scholten, A.4
Berlin, I.5
Geurink, P.P.6
de Jong, A.7
Goerdayal, S.8
Neefjes, J.9
Heck, A.J.R.10
-
38
-
-
0036775490
-
Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family
-
Borodovsky A., Ovaa H., Kolli N., Gan-Erdene T., Wilkinson K.D., Ploegh H.L., Kessler B.M. Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family. Chem Biol 2002, 9:1149-1159.
-
(2002)
Chem Biol
, vol.9
, pp. 1149-1159
-
-
Borodovsky, A.1
Ovaa, H.2
Kolli, N.3
Gan-Erdene, T.4
Wilkinson, K.D.5
Ploegh, H.L.6
Kessler, B.M.7
-
39
-
-
84876105929
-
Covalent inhibition of SUMO and ubiquitin-specific cysteine proteases by an in situ thiol-alkyne addition
-
Sommer S., Weikart N.D., Linne U., Mootz H.D. Covalent inhibition of SUMO and ubiquitin-specific cysteine proteases by an in situ thiol-alkyne addition. Bioorg Med Chem 2013, 21:2511-2517.
-
(2013)
Bioorg Med Chem
, vol.21
, pp. 2511-2517
-
-
Sommer, S.1
Weikart, N.D.2
Linne, U.3
Mootz, H.D.4
-
41
-
-
82255181181
-
Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes
-
Altun M., Kramer H.B., Willems L.I., McDermott J.L., Leach C.A., Goldenberg S.J., Kumar K.G.S., Konietzny R., Fischer R., Kogan E., et al. Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes. Chem Biol 2011, 18:1401-1412.
-
(2011)
Chem Biol
, vol.18
, pp. 1401-1412
-
-
Altun, M.1
Kramer, H.B.2
Willems, L.I.3
McDermott, J.L.4
Leach, C.A.5
Goldenberg, S.J.6
Kumar, K.G.S.7
Konietzny, R.8
Fischer, R.9
Kogan, E.10
-
42
-
-
84867193114
-
Ubiquitin-based probes prepared by total synthesis to profile the activity of deubiquitinating enzymes
-
de Jong A., Merkx R., Berlin I., Rodenko B., Wijdeven R.H.M., Atmioui El D., Yalçin Z., Robson C.N., Neefjes J.J., Ovaa H. Ubiquitin-based probes prepared by total synthesis to profile the activity of deubiquitinating enzymes. ChemBioChem 2012, 13:2251-2258.
-
(2012)
ChemBioChem
, vol.13
, pp. 2251-2258
-
-
de Jong, A.1
Merkx, R.2
Berlin, I.3
Rodenko, B.4
Wijdeven, R.H.M.5
Atmioui El, D.6
Yalçin, Z.7
Robson, C.N.8
Neefjes, J.J.9
Ovaa, H.10
-
43
-
-
84904637945
-
Using chemistry to investigate the molecular consequences of protein ubiquitylation
-
Abeywardana T., Pratt M.R. Using chemistry to investigate the molecular consequences of protein ubiquitylation. ChemBioChem 2014, 15:1547-1554.
-
(2014)
ChemBioChem
, vol.15
, pp. 1547-1554
-
-
Abeywardana, T.1
Pratt, M.R.2
-
44
-
-
0027944205
-
Synthesis of proteins by native chemical ligation
-
Dawson P.E., Muir T.W., Clark-Lewis I., Kent S.B. Synthesis of proteins by native chemical ligation. Science 1994, 266:776-779.
-
(1994)
Science
, vol.266
, pp. 776-779
-
-
Dawson, P.E.1
Muir, T.W.2
Clark-Lewis, I.3
Kent, S.B.4
-
45
-
-
71049127491
-
Synthesis of 4-mercapto-L-lysine derivatives: potential building blocks for sequential native chemical ligation
-
Pasunooti K.K., Yang R., Vedachalam S., Gorityala B.K., Liu C-F., Liu X-W. Synthesis of 4-mercapto-L-lysine derivatives: potential building blocks for sequential native chemical ligation. Bioorg Med Chem Lett 2009, 19:6268-6271.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 6268-6271
-
-
Pasunooti, K.K.1
Yang, R.2
Vedachalam, S.3
Gorityala, B.K.4
Liu, C.-F.5
Liu, X.-W.6
-
46
-
-
78649575597
-
Total chemical synthesis of di-ubiquitin chains
-
Kumar K.S.A., Spasser L., Erlich L.A., Bavikar S.N., Brik A. Total chemical synthesis of di-ubiquitin chains. Angew Chem Int Ed Engl 2010, 49:9126-9131.
-
(2010)
Angew Chem Int Ed Engl
, vol.49
, pp. 9126-9131
-
-
Kumar, K.S.A.1
Spasser, L.2
Erlich, L.A.3
Bavikar, S.N.4
Brik, A.5
-
47
-
-
84910092035
-
Total chemical synthesis of ubiquitin, ubiquitin mutants and derivatives thereof
-
13/823,728
-
Ovaa H, Oualid El F, Merkx R: Total chemical synthesis of ubiquitin, ubiquitin mutants and derivatives thereof. US Patent Application US 13/823,728, 2010-09-15.
-
(2010)
, vol.728
-
-
Ovaa, H.1
Oualid El, F.2
Merkx, R.3
-
48
-
-
67650620318
-
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes
-
Reyes-Turcu F.E., Ventii K.H., Wilkinson K.D. Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes. Annu Rev Biochem 2009, 78:363-397.
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 363-397
-
-
Reyes-Turcu, F.E.1
Ventii, K.H.2
Wilkinson, K.D.3
-
49
-
-
84863449135
-
Profiling ubiquitin linkage specificities of deubiquitinating enzymes with branched ubiquitin isopeptide probes
-
Iphöfer A., Kummer A., Nimtz M., Ritter A., Arnold T., Frank R., van den Heuvel J., Kessler B.M., Jänsch L., Franke R. Profiling ubiquitin linkage specificities of deubiquitinating enzymes with branched ubiquitin isopeptide probes. ChemBioChem 2012, 13:1416-1420.
-
(2012)
ChemBioChem
, vol.13
, pp. 1416-1420
-
-
Iphöfer, A.1
Kummer, A.2
Nimtz, M.3
Ritter, A.4
Arnold, T.5
Frank, R.6
van den Heuvel, J.7
Kessler, B.M.8
Jänsch, L.9
Franke, R.10
-
50
-
-
84890859198
-
Deubiquitinating enzyme specificity for ubiquitin chain topology profiled by di-ubiquitin activity probes
-
McGouran J.F., Gaertner S.R., Altun M., Kramer H.B., Kessler B.M. Deubiquitinating enzyme specificity for ubiquitin chain topology profiled by di-ubiquitin activity probes. Chem Biol 2013, 20:1447-1455.
-
(2013)
Chem Biol
, vol.20
, pp. 1447-1455
-
-
McGouran, J.F.1
Gaertner, S.R.2
Altun, M.3
Kramer, H.B.4
Kessler, B.M.5
-
51
-
-
84889020913
-
Activity-based diubiquitin probes for elucidating the linkage specificity of deubiquitinating enzymes
-
Li G., Liang Q., Gong P., Tencer A.H., Zhuang Z. Activity-based diubiquitin probes for elucidating the linkage specificity of deubiquitinating enzymes. Chem Commun (Camb) 2014, 50:216-218.
-
(2014)
Chem Commun (Camb)
, vol.50
, pp. 216-218
-
-
Li, G.1
Liang, Q.2
Gong, P.3
Tencer, A.H.4
Zhuang, Z.5
-
52
-
-
84896760735
-
Dehydroalanine-based diubiquitin activity probes
-
Haj-Yahya N., Hemantha H.P., Meledin R., Bondalapati S., Seenaiah M., Brik A. Dehydroalanine-based diubiquitin activity probes. Org Lett 2014, 16:540-543.
-
(2014)
Org Lett
, vol.16
, pp. 540-543
-
-
Haj-Yahya, N.1
Hemantha, H.P.2
Meledin, R.3
Bondalapati, S.4
Seenaiah, M.5
Brik, A.6
-
53
-
-
84899659989
-
A native chemical ligation handle that enables the synthesis of advanced activity-based probes: diubiquitin as a case study
-
Mulder M.P.C., Oualid El F., Beek Ter J., Ovaa H. A native chemical ligation handle that enables the synthesis of advanced activity-based probes: diubiquitin as a case study. ChemBioChem 2014, 15:946-949.
-
(2014)
ChemBioChem
, vol.15
, pp. 946-949
-
-
Mulder, M.P.C.1
Oualid El, F.2
Beek Ter, J.3
Ovaa, H.4
-
54
-
-
84871298878
-
Conformational stabilization of ubiquitin yields potent and selective inhibitors of USP7
-
Zhang Y., Zhou L., Rouge L., Phillips A.H., Lam C., Liu P., Sandoval W., Helgason E., Murray J.M., Wertz I.E., et al. Conformational stabilization of ubiquitin yields potent and selective inhibitors of USP7. Nat Chem Biol 2013, 9:51-58.
-
(2013)
Nat Chem Biol
, vol.9
, pp. 51-58
-
-
Zhang, Y.1
Zhou, L.2
Rouge, L.3
Phillips, A.H.4
Lam, C.5
Liu, P.6
Sandoval, W.7
Helgason, E.8
Murray, J.M.9
Wertz, I.E.10
-
55
-
-
84873085753
-
A strategy for modulation of enzymes in the ubiquitin system
-
Ernst A., Avvakumov G., Tong J., Fan Y., Zhao Y., Alberts P., Persaud A., Walker J.R., Neculai A-M., Neculai D., et al. A strategy for modulation of enzymes in the ubiquitin system. Science 2013, 339:590-595.
-
(2013)
Science
, vol.339
, pp. 590-595
-
-
Ernst, A.1
Avvakumov, G.2
Tong, J.3
Fan, Y.4
Zhao, Y.5
Alberts, P.6
Persaud, A.7
Walker, J.R.8
Neculai, A.-M.9
Neculai, D.10
|