Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 6, 2011, Pages 2222-2227

  James, Terrence W ^a   Frias Staheli, Natalia ^a,e   Bacik, John Paul ^a   Levingston Macleod, Jesica M ^a   Khajehpour, Mazdak ^b   García Sastre, Adolfo ^a,c,d   Mark, Brian L ^a  

^a Department of Microbiology ^*  (United States)

^b UNIVERSITY OF MANITOBA   (Canada)

^c Division of Infectious Diseases   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Bunyavirus; Crimean Congo haemorrhagic fever virus; Innate immunity; Viral deubiquitinase; Viral immune evasion

Indexed keywords

INTERFERON STIMULATED GENE 15; PROTEIN; PROTEINASE; UBIQUITIN; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CROSS REACTION; CRYSTAL STRUCTURE; ENZYME SPECIFICITY; EUKARYOTE; NAIRO VIRUS; NONHUMAN; OVARY TUMOR; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; UBIQUITINATION; YEAST;

CRYSTALLOGRAPHY, X-RAY; CYTOKINES; FEMALE; HEMORRHAGIC FEVER VIRUS, CRIMEAN-CONGO; HUMANS; OVARIAN NEOPLASMS; PEPTIDE HYDROLASES; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; UBIQUITIN; UBIQUITINS; VIRAL PROTEINS;

CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS; EUKARYOTA; NAIROVIRUS; ORTHOBUNYAVIRUS;

EID: 79952290477     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1013388108     Document Type: Article

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