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Volumn 16, Issue 2, 2014, Pages 540-543

Dehydroalanine-based diubiquitin activity probes

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; DEHYDROALANINE; DEUBIQUITINASE; DRUG DERIVATIVE; LYSINE; UBD PROTEIN, HUMAN; UBIQUITIN;

EID: 84896760735     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol403416w     Document Type: Article
Times cited : (84)

References (26)
  • 7
    • 82255181181 scopus 로고    scopus 로고
    • Altun, M.; et al. Chem. Biol. 2011, 18, 1401.
    • (2011) Chem. Biol. , vol.18 , pp. 1401
    • Altun, M.1
  • 15
    • 84896800438 scopus 로고    scopus 로고
    • While this manuscript was under preparation and under review, two papers were published reporting the preparation of di-Ub probes:
    • While this manuscript was under preparation and under review, two papers were published reporting the preparation of di-Ub probes:
  • 16
    • 84889020913 scopus 로고    scopus 로고
    • Zhuang and co-workers reported activity-based di-Ub probes (K48 and K63) by introducing Michael acceptor in the linker between the two Ubs. The authors mutated the desired Lys residue with Cys in the proximal Ub, which was reacted with the C-terminal of the other Ub bearing α-bromo-unsaturated ketone functionality. For more details
    • Zhuang and co-workers reported activity-based di-Ub probes (K48 and K63) by introducing Michael acceptor in the linker between the two Ubs. The authors mutated the desired Lys residue with Cys in the proximal Ub, which was reacted with the C-terminal of the other Ub bearing α-bromo-unsaturated ketone functionality. For more details see: Li, G.; Liang, Q.; Gong, P.; Tencer, A. H.; Zhuang, Z. Chem. Commun. 2014, 50, 216.
    • (2014) Chem. Commun. , vol.50 , pp. 216
    • Li, G.1    Liang, Q.2    Gong, P.3    Tencer, A.4    Zhuang, Z.5
  • 17
    • 84896780979 scopus 로고    scopus 로고
    • Kessler and co-workers reported di-Ub probes based on all eight different linkages in which the proximal Ub was linked by Cu(I)-catalyzed 1,4-triazole formation to the C terminus of the distal Ub bearing a reactive electrophile. For more details DOI: 10.1016/j.chembiol.2013.10.012
    • Kessler and co-workers reported di-Ub probes based on all eight different linkages in which the proximal Ub was linked by Cu(I)-catalyzed 1,4-triazole formation to the C terminus of the distal Ub bearing a reactive electrophile. For more details, see: McGouran, J. F.; Gaertner, S. R.; Altun, M.; Kramer, H. B.; Kessler, B. M. Chem. Biol. DOI: 10.1016/j.chembiol.2013.10.012.
    • Chem. Biol
    • McGouran, J.1    Gaertner, S.2    Altun, M.3    Kramer, H.4    Kessler, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.